• Journal of Biomedical Engineering Research
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• v.12 no.3
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• pp.191-202
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• 1991

This paper describes ECG data compression algorithm using neural network. As a learning method, we use back error propagation algorithm. ECG data compression is performed using learning ability of neural network. CSE database, which is sampled 12bit digitized at 500samp1e/sec, is selected as a input signal. In order to reduce unit number of input layer, we modify sampling ratio 250samples/sec in QRS complex, 125samples/sec in P & T wave respectively. hs a input pattern of neural network, from 35 points backward to 45 points forward sample Points of R peak are used.

• Genomics & Informatics
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• v.4 no.3
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• pp.125-128
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• 2006

We present an openfree hypertext (also known as wiki) web cluster called BioCC. BioCC is a novel wiki farm that lets researchers create hundreds of biological web sites. The web sites form an organic information network. The contents of all the sites on the BioCC wiki farm are modifiable by anonymous as well as registered users. This enables biologists with diverse backgrounds to form their own Internet bio-communities. Each community can have custom-made layouts for information, discussion, and knowledge exchange. BioCC aims to form an ever-expanding network of openfree biological knowledge databases used and maintained by biological experts, students, and general users. The philosophy behind BioCC is that the formation of biological knowledge is best achieved by open-minded individuals freely exchanging information. In the near future, the amount of genomic information will have flooded society. BioGG can be an effective and quickly updated knowledge database system. BioCC uses an opensource wiki system called Mediawiki. However, for easier editing, a modified version of Mediawiki, called Biowiki, has been applied. Unlike Mediawiki, Biowiki uses a WYSIWYG (What You See Is What You Get) text editor. BioCC is under a share-alike license called BioLicense (http://biolicense.org). The BioCC top level site is found at http://bio.cc/

• Proceedings of the Korean Society of Applied Entomolohy Conference
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• 2001.05a
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• pp.61-61
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• 2001

• 한국생물공학회:학술대회논문집
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• 2000.04a
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• pp.442-445
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• 2000

Amphiphilic polyurethane(APU) particle is a polymeric surfactant, and could increase the solubility of 2-methylnaphthalene significantly. 2-Methylnaphthalene was recovered by the precipitation of APU particles and was degraded by Acinetobacter sp. K2-2. APU particle was recovered and reused after treatment of triethylamine.

• Genomics & Informatics
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• v.3 no.2
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• pp.47-51
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• 2005

Molecular mechanisms of biological processes are typically represented as 'pathways' that have a graph­analogical network structure. However, due to the diversity of topics that pathways cover, their constituent biological entities are highly diverse and the semantics is embedded implicitly. The kinds of interactions that connect biological entities are likewise diverse. Consequently, how to model or process pathway data is not a trivial issue. In this review article, we give an overview of the challenges in pathway database development by taking the INOH project as an example.

• The Journal of the Institute of Internet, Broadcasting and Communication
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• v.20 no.2
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• pp.165-170
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• 2020

The spiking neural network operates in a different mechanism than the existing neural network. The existing neural network transfers the output value to the next neuron via an activation function that does not take into account the biological mechanism for the input value to the neuron that makes up the neural network. In addition, there have been good results using deep structures such as VGGNet, ResNet, SSD and YOLO. spiking neural networks, on the other hand, operate more like the biological mechanism of real neurons than the existing activation function, but studies of deep structures using spiking neurons have not been actively conducted compared to in-depth neural networks using conventional neurons. This paper proposes the method of loading an deep neural network model made from existing neurons into a conversion tool and converting it into a spiking deep neural network through the method of replacing an existing neuron with a spiking neuron.

• Proceedings of the Korean Society of Potoscience Conference
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• 2005.06a
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• pp.54-54
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• 2005

• The Journal of the Korea Contents Association
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• v.15 no.10
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• pp.616-625
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• 2015

Currently, oriental medicine research is focused with modern research technology and validate it's various biochemical effect by combining with molecular biology technology. But there are few searching system for finding biochemical mechanism which is related to major compounds in oriental medicine. In this research, we aimed developing korean herb database based on text-mining system by analyzing PubMed data. We have developed prototype system for searching chemical, gene and biological relation in oriental medicine. It is characterized by modern oriental medicine research trend with major chemical, gene and protein information. Analysis results can be searched on the prototype system with visualization of the biological interactions.

• Science of Emotion and Sensibility
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• v.20 no.2
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• pp.161-170
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• 2017

Emotion affects many parts of human life such as learning ability, behavior and judgment. It is important to understand human nature. Emotion can only be inferred from facial expressions or gestures, what it actually is. In particular, emotion is difficult to classify not only because individuals feel differently about emotion but also because visually induced emotion does not sustain during whole testing period. To solve the problem, we acquired bio-signals and extracted features from those signals, which offer objective information about emotion stimulus. The emotion pattern classifier was composed of unsupervised learning algorithm with hidden nodes and feature vectors. Restricted Boltzmann machine (RBM) based on probability estimation was used in the unsupervised learning and maps emotion features to transformed dimensions. The emotion was characterized by non-linear classifiers with hidden nodes of a multi layer neural network, named deep belief network (DBN). The accuracy of DBN (about 94 %) was better than that of back-propagation neural network (about 40 %). The DBN showed good performance as the emotion pattern classifier.

• Interdisciplinary Bio Central
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• v.5 no.1
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• pp.1.1-1.8
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• 2013

High quality publicly-available transcriptomic data representing relationships in gene expression across a diverse set of biological conditions is used as a context network to explore transcriptomics of the CNS. The context network, 18367Hu-matrix, contains pairwise Pearson correlations for 22,215 human genes across18,637 human tissue samples1. To do this, we compute a network derived from biological samples from CNS cells and tissues, calculate clusters of co-expressed genes from this network, and compare the significance of these to clusters derived from the larger 18367Hu-matrix network. Sorting and visualization uses the publicly available software, MetaOmGraph (http://www.metnetdb.org/MetNet_MetaOm-Graph.htm). This identifies genes that characterize particular disease conditions. Specifically, differences in gene expression within and between two designations of glial cancer, astrocytoma and glioblastoma, are evaluated in the context of the broader network. Such gene groups, which we term outlier-networks, tease out abnormally expressed genes and the samples in which this expression occurs. This approach distinguishes 48 subnetworks of outlier genes associated with astrocytoma and glioblastoma. As a case study, we investigate the relationships among the genes of a small astrocytoma-only subnetwork. This astrocytoma-only subnetwork consists of SVEP1, IGF1, CHRNA3, and SPAG6. All of these genes are highly coexpressed in a single sample of anaplastic astrocytoma tumor (grade III) and a sample of juvenile pilocytic astrocytoma. Three of these genes are also associated with nicotine. This data lead us to formulate a testable hypothesis that this astrocytoma outlier-network provides a link between some gliomas/astrocytomas and nicotine.