• Interdisciplinary Bio Central
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• 제3권3호
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• pp.12.1-12.3
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• 2011

Bioinformatics tools and databases are useful for understanding and processing various biological data. Numerous resources are being published each year. It is not a trivial task to find up-to-date relevant tools and databases. Moreover, no server is available to provide comprehensive coverage on bioinformatics resources in all biological fields. Here, we present a directory server called IntoPub that provides information on web resources. First, we downloaded XML-formatted abstracts containing web URLs from the NCBI PubMed database by using 'ESearch-EFetch' function in the NCBI E-utilities. The information is obtained from abstracts in the PubMed by extracting 'www' or 'http' prefixes. Then, we cu-rate the downloaded abstracts both in automatic and manual fashion. As of July 2011, the IntoPub database has 12,118 abstracts containing web URLs from 174 journals. Our anal-ysis shows that the number of abstracts containing web resources has increased signifi-cantly every year. The server has been tested by many biologists from several countries to get opinion on user satisfaction, usefulness, practicability, and ease of use since January 2010. In the IntoPub web server, users can easily find relevant bioinformatics resources, as compared to searching in PubMed. IntoPub will continue to update and incorporate new web resources from PubMed and other literature databases. IntoPub, available at http://into.kobic.re.kr/, is updated every day.

• 한국축산식품학회지
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• 제43권2호
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• pp.197-219
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• 2023

Rabbit meat has high nutritional and dietetic characteristics, but its consumption rate is comparatively lower than other meat types. The nutritional profile of rabbit meat, by comparison with beef, pork, and poultry, is attributed to relatively higher proportions of n-3 fatty acids and low amounts of intramuscular fat, cholesterol, and sodium, indicating its consumption may provide health benefits to consumers. But, the quality attributes of rabbit meat can be originated from different factors such as genetics, environment, diet, rearing system, pre-, peri-, and post-slaughter conditions, and others. Different rabbit breeds and the anatomical location of muscles may also affect the nutritional profile and physicochemical properties of rabbit meat. However, adequate information about the effect of those two factors on rabbit meat is limited. Therefore, cumulative information on nutritional composition and carcass and meat quality attributes of rabbit meat in terms of different breeds and muscle types and associated factors is more important for the production and processing of rabbits. Moreover, some studies reported that rabbit meat proteins exhibited angiotensin-converting enzyme inhibitory characteristics and antioxidant properties. The aim of this review is to elucidate the determinants of rabbit meat quality of different breeds and its influencing factors. In addition, the proven biological activities of rabbit meat are introduced to ensure consumer satisfaction.

• Mass Spectrometry Letters
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• 제5권1호
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• pp.16-23
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• 2014

Liquid chromatography based mass spectrometry (LC-MS) is a key technology for analyzing highly complex and dynamic proteome samples. With highly accurate and sensitive LC-MS analysis of complex proteome samples, efficient data processing is another critical issue to obtain more information from LC-MS data. A typical proteomic data processing starts with protein database search engine which assigns peptide sequences to MS/MS spectra and finds proteins. Although several search engines, such as SEQUEST and MASCOT, have been widely used, there is no unique standard way to interpret MS/MS spectra of peptides. Each search engine has pros and cons depending on types of mass spectrometers and physicochemical properties of peptides. In this study, we describe a novel data process pipeline which identifies more peptides and proteins by correcting precursor ion mass numbers and unifying multi search engines results. The pipeline utilizes two open-source software, iPE-MMR for mass number correction, and iProphet to combine several search results. The integrated pipeline identified 25% more proteins in mouse epididymal adipose tissue compared with the conventional method. Also the pipeline was validated using control and colitis induced colon tissue. The results of the present study shows that the integrated pipeline can efficiently identify increased number of proteins compared to the conventional method which can be a breakthrough in identification of a potential biomarker candidate.

• 대한의용생체공학회:의공학회지
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• 제16권2호
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• pp.201-208
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• 1995

The information obtained from the analysis of respiratory muscle elecromyographic (EMG) activities provides a mean for studying muscular activity in relation to the ventilatory process. Thus, in order to comprehend the airflow pattern and its brain control, signal processing is required to characterize respiratory muscle activity. This paper presents a computerized method for the analysis of the electrical activity of the respiratory muscles of premature lambs, and focuses upon the automatic determination of respiratory timing points such as onset and cessation points of the burst activity. Based on experimental results, reliable timing points can be obtained using the proposed methodology.

• 감성과학
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• 제5권3호
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• pp.11-20
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• 2002

There are Two new models developed for objective evaluation of fabric color patterns by applying a multiple regression analysis and an adaptive foray-rule-based system. The physical features of fabric color patterns are extracted through digital image processing and the emotional features are collected based on the psychological experiments of Soen[3, 4]. The principle physical features are hue, saturation, intensity and the texture of color patterns. The emotional features arc represented thirteen pairs of adverse adjectives. The multiple regression analyses and the adaptive fuzzy system are used as a tool to analyze the relations between physical and emotional features. As a result, both of the proposed models show competent performance for the approximation and the similar linguistic interpretation to the Soen's psychological experiments.

• Journal of Computing Science and Engineering
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• 제4권4호
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• pp.350-367
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• 2010

Microarray technology is an interdisciplinary technique that promises a revolutionary progress toward better health and improved quality of life. The paper focuses on the development of an efficient software package, equipped with already well-known methods; also some new methods are proposed that will allow the processing and analysis of thousands of genes on microarray images. The microarray analysis software package (called SmartArray), newly proposed in this paper verifies, through microarray analysis, dramatic changes in the mRNA, protein, and activity level in the rat retina during light deprivation, which have been demonstrated in previous biological experiments. The analysis results demonstrate that SmartArray can successfully find many changes in gene expression levels in each subarray and classify them according to their significance.

• 대한의용생체공학회:의공학회지
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• 제15권1호
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• pp.63-70
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• 1994

A medical image workstation was developed using multimedia technique. The system based on PC-486DX was designed to acquire medical images produced by medical imaging instruments and related audio information, that is, doctors'reporting results. Input int'ormation was processed and analyzed, then the results were presented in the form of graph and animation. All the informations of the system were hierarchically related with the image as the apex. Processing and Analysis algorithms were implemented so that the diagnostic accuracy could be improved. The diagnosed id'ormation can be transferred for patient diagnosis through LAN (local area network).

• 대한의용생체공학회:의공학회지
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• 제5권1호
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• pp.85-92
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• 1984

A new architecture of the Digital Scan Converter (DSC) for the linear-scan ultrasound medical imaging systems is proposed and its hardware implementation is reported. While the conventional DSC merely displays the acquisited data and does nor allow access to the frame memory, it is possible, in the new system, to access to the frame memory for further imaging processing so as to obtain useful information for medical diagnosis. Image processing can be performed either by a special pupose processor, or by VAX 11/780. The system is made to operate asyncronously to increase the frame rate with tags assigned to the data. The proposed DSC was designed to be used without much modification for the sector scan system as well.

• 대한의용생체공학회:학술대회논문집
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• 대한의용생체공학회 1997년도 춘계학술대회
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• pp.195-198
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• 1997

A medical information management system for small to medium sized clinics and hospitals is developed. The system is designed to process, analyze and manage each patient's clinical record using database technique. The structure of the database was determined and implemented through careful and rigorous study of medical practices in Korea and, therefore, reflects the needs of information management in Korean medical community. Furthermore, a sophisticated inference engine that can deduce possible diseases from the result of medical examination is added to the system to provide doctors with a guideline in medical diagnoses.

• International Journal of Advanced Culture Technology
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• 제5권2호
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• pp.98-105
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• 2017

Smartphones are fast growing in the IT market and are the most influential devices in our daily life. Smartphones are being studied for their use in body sensor networks with excellent processing power and wireless communication technology. In this paper, we propose a coordinator design that provides data collection, classification, and display using based on Android-smartphone in multiple sensor nodes. The coordinator collects data of sensor nodes that measure biological patterns using wireless communication technologies such as Bluetooth and NFC. The coordinator constructs a network using a multiple-level scheduling algorithm for efficient data collection at multiple sensor nodes. Also, to support different protocols between heterogeneous sensors, a data sheet recording wireless communication protocol information is used. The designed coordinator used Arduino to test the performance of multiple sensor node environments.