• 제목/요약/키워드: biochemical research

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Bioprocess Optimization - a Challenge

  • PANDA;TAPOBRATA;P.S.R.BABU;J.A.KUMARI;D.S.RAO;K.THEODORE;K.JAGANNANDHA-RAO;S.SIVA-KESAVA;A.KAPAT;S.R.NAIR;J.SINHA;R.SREENIVAS;G.LAKSHMI-PRASANNA;V.VENKATA-DASU;P.ARTHUR-FELSE;G.S.NAIDU;B.GOKUL;S.UMA;K.SRIVIDYA;R.V.MURALIDHAR;K.BALAMURUGAN;K.CHANDRASEKHAR;M.PAZOUKI
    • Journal of Microbiology and Biotechnology
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    • 제7권6호
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    • pp.367-372
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    • 1997
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The Influence of Bisphenol A on the Thyroid Hormone System in vivo

  • Cho, Mi-Young;Jung, Ki-Kyung;Nam, Kyung-Tak;Kang, Ju-Hye;Kang, Seog-Youn;Chung, Hye-Joo;Kim, Ju-Il;Lee, Young-Don;Na, Han-Kwang
    • 대한약학회:학술대회논문집
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    • 대한약학회 2003년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.1
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    • pp.185.3-186
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    • 2003
  • It is well-known that bisphenol A(BPA), an industrial raw material for polycarbonate and epoxy resins, shows estrogenic activity. Recent research from our laboratory has shown that SPA disrupts interaction between thyroid hormone and its receptor in a non-competitive manner, and alters the thyroid-hormone dependent expression of growth hormone(GH) and prolactin(PRL). (omitted)

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THE EFFECT OF BISPHENOL A ON THE THYROID HORMONE SYSTEM FOR THE ESTABLISHMENT OF SCREENING METHOD OF ENDOCRINE DISRUPTORS

  • Cho, Mi-Young;Lim, Myung-Sin;Lee, Young-Choi;Jung, Ki-Kyung;Nam, Kyung-Tak;Kim, Tae-Gyun;Kang, Ju-Hye;Kang, Seog-Youn;Kim, Seung-Hee
    • 한국독성학회:학술대회논문집
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    • 한국독성학회 2002년도 Molecular and Cellular Response to Toxic Substances
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    • pp.162-162
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    • 2002
  • There has been many findings of natural, environmental or manufactered nonsteroidal substances shown to have estrogenic activity. Since estrogens affect reproduction and cellular development to cause disease in people or animals, chronic exposure may have a major impact on health.(omitted)

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고려홍삼의 지용성 분획에 의한 세로토닌 방출의 억제 (Inhibition of Perotonin Release by Lipophilic Fraction From Korean Red Ginseng)

  • Rhee, Man-Hee;Park, Kyeong-Mee;Park, Hwa-Jin;Nam, Ki-Yeul;Park, Ki-Hyun
    • Journal of Ginseng Research
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    • 제17권2호
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    • pp.127-130
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    • 1993
  • Lipophilic Fraction (LF) from Panax ginseng C.A. Meyer strongly inhibited human platelet aggregations induced by thrombin. When platelets were prelabeled with 5-hydroxy[G-$^3$H]-tryptamine (serotonin) and then stimulated by thrombin, LF inhibited the release of serotonin in a dose-dependent manner. From this result, we suggest that LF have antiplatelet and antimigraine functions by inhibiting the release of serotonin.

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한우의 연령에 따른 혈액 및 혈청 화학치 분석 (Hematological and biochemical analysis of Korean indigenous cattle according to the ages)

  • 조현웅;고원석;손향원;이미진;송희종;박진호
    • 한국동물위생학회지
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    • 제31권1호
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    • pp.137-147
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    • 2008
  • Investigations for hematologic and biochemical values and the differential count of WBC for Korean indigenous cattle (KIC)is rarely performed. Therefore, when the index of complete blood counts (CBC) and biochemical analysis of KIC was requested, it had many difficulties to make the results for blood condition since the standard hematologic and biochemical values of KIC are lacking. In the present study, we have investigated the hematologic and biochemical values and the differential count of WBC for blood of total 252 KIC and 17 striped cattle (SC) as a control. As a result, the mean values of RBC and platelet of KIC were significantly decreased by age (P<0.05). The mean values of RBC, HCT, MCV and MCHC between KIC and SC of the same age (2 - 3 years) showed the statistical significance (P<0.05). Also, in the WBC of KIC, the mean values were decreased according to the age from $12.8{\times}10^3/{\mu}l$ under 1 year to $8.5{\times}10^3/{\mu}l$ over 5 years. In the differential count of WBC of KIC, it showed generally the rates of 45% lymphocyte and 35% segmented neutrophil. In the biochemical analysis, the mean values of BUN and globulin were significantly increased according to the age (P<0.05). Additionally, in comparative analysis between pregnant and non-pregnant group of KIC, the mean values of Hg and HCT in pregnant group were significantly decreased (P<0.05). In conclusion, data obtained from this study may be valuable as a standard for interpretation of the results in hematologic and biochemical analysis of KIC.