• Proceedings of the Materials Research Society of Korea Conference
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• 2009.05a
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• pp.13.2-13.2
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• 2009

Electrostatic printing either it is drop-on-demand or continuous has immense applications in non-contact printing systems such as solar cells, flexible printed circuits, RFIDs and bio applications. In this paper a laboratory manufactured nozzle has been designed for the experimental investigation of electrostatic dripping and atomization of liquid. Dripping and atomization conditions such as voltage, nozzle tip diameter, distance between counter electrode and flowrate has been indentified for the designed nozzle. Furthermore it is also demonstrated that the diameter of a generated droplet could be reduced from a significantly large size to a narrow size distribution which can be controlled by volumetric flow rate and applied voltage. This study will help in classify the conditions between different electrostatic dripping mode such as drop-on-demand formation, jet mode and finally the atomization mode based on the laboratory fabricated nozzle head.

• Journal of the Semiconductor & Display Technology
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• v.20 no.3
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• pp.125-130
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• 2021

Scaffold is used to produce bio sensor. Scaffold is required high dimensional accuracy. 3D printer is used to manufacture scaffold. 3D printer can't detect defect during printing. Defect detection is very important in scaffold printing. Real-time defect detection is very necessary on industry. In this paper, we proposed the method for real-time scaffold defect detection. Real-time defect detection model is produced using CNN(Convolution Neural Network) algorithm. Performance of the proposed model has been verified through evaluation. Real-time defect detection system are manufactured on hardware. Experiments were conducted to detect scaffold defects in real-time. As result of verification, the defect detection system detected scaffold defect well in real-time.

• Journal of Korea Technical Association of The Pulp and Paper Industry
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• v.45 no.1
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• pp.1-5
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• 2013

Printing papers published in between 1950's and 1990's were treated with three methods such as distilled water washing, $CaCO_3$ solution washing and methyl cellulose solution coating for improving their conservational properties. Accelerated aging with $80^{\circ}C$ and 80% RH for 14 days was applied to the testing papers. Results showed that distilled water and $CaCO_3$ washing kept increased pH even after accelerated aging, but did not improve folding endurances for 1950's-60's papers. Methyl cellulose treatment did not increased pH of the old papers, but increased folding endurances remarkably for 1950's-60's papers even after accelerated aging. It suggests that methyl cellulose treatment after $CaCO_3$ washing should give improvements both in pH and folding endurance.

• Journal of the Korean Society of Manufacturing Process Engineers
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• v.21 no.4
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• pp.107-113
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• 2022

At present, it is possible to manufacture electrodes down to several micrometers (~ ㎛) using inkjet printing technology owing to the development of precision ejection heads. Inkjet printing technology is also used in the manufacturing of bio-sensors, electronic sensors, and flexible displays. To reduce the difference between the electrode design/simulation performance and actual printing pattern performance, it is necessary to analyze and optimize the processable area of the ink material, which is a fluid. In this study, process optimization was conducted to manufacture an IDE pattern and fabricate an impedance sensor. A total of 25 IDE patterns were produced, with five for each lamination process. Electrode line width and height changes were measured by stacking the designed IDE pattern with a nanoparticle-based conductive ink multilayer. Furthermore, the optimal process area for securing a performance close to the design result was analyzed through impedance and capacitance. It was observed that the increase in the height of stack layer 4 was the lowest at 4.106%, and the increase in capacitance was measured to be the highest at 44.08%. The proposed stacking process pattern, which is optimized in terms of uniformity, reproducibility, and performance, can be efficiently applied to bio-applications such as biomaterial sensing with an impedance sensor.

• JSTS:Journal of Semiconductor Technology and Science
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• v.7 no.3
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• pp.133-139
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• 2007

Future MEMS systems will be composed of larger varieties of devices with very different functionality such as electronics, mechanics, optics and bio-chemistry. Integration technology of heterogeneous devices must be developed. This article first deals with the current development trend of new fabrication technologies; those include self-assembling of parts over a large area, wafer-scale encapsulation by wafer-bonding, nano imprinting, and roll-to-roll printing. In the latter half of the article, the concept towards the heterogeneous integration of devices and functionality into micro/nano systems is described. The key idea is to combine the conventional top-down technologies and the novel bottom-up technologies for building nano systems. A simple example is the carbon nano tube interconnection that is grown in the via-hole of a VLSI chip. In the laboratory level, the position-specific self-assembly of nano parts on a DNA template was demonstrated through hybridization of probe DNA segments attached to the parts. Also, bio molecular motors were incorporated in a micro fluidic system and utilized as a nano actuator for transporting objects in the channel.

• Biotechnology and Bioprocess Engineering:BBE
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• v.9 no.2
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• pp.137-142
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• 2004

In this study, a simple procedure is described for patterning biotin on a glass substrate and then selectively immobilizing proteins of interest onto the biotin-patterned surface. Microcontact printing (CP) was used to generate the micropattern of biotin and to demonstrate the selective immobilization of proteins by using enhanced green fluorescent protein (EGFP) as a model protein, of which the C-terminus was fused to a core streptavidin (cSA) gene of Streptomyces avidinii. Confocal fluorescence microscopy was used to visualize the pattern of the immobilized protein (EGFP-cSA), and surface plasmon resonance was used to characterize biological activity of the immobilized EGFP-cSA. The results suggest that this strategy, which consists of a combination of $\mu$CP and cSA-fused proteins. is an effective way for fabricating biologically active substrates that are suitable for a wide variety of applications. one such being the use in protein-protein assays.

• Journal of Biomedical Engineering Research
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• v.39 no.1
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• pp.22-29
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• 2018

Intervertebral disc(IVD) mainly consists of Annulus fibrosus(AF) and Nucleus pulposus(NP), playing a role of distributing a mechanical load on vertebral body. IVD tissue engineering has been developed the methods to achieve anatomic morphology and restoration of biological function. The goal of present study is to identify the possibilities for creating a substitute of IVD the morphology and biological functions are the same as undamaged complete IVD. To fabricate the AF and NP combine biphasic IVD tissue, AF tissue scaffolds have been printed by 3D bio-printing system with natural biomaterials and NP tissues have been prepared by scaffold-free culture system. We evaluated whether the combined structure of 3D printed AF scaffold and scaffold-free NP tissue construct could support the architecture and cell functions as IVD tissue. 3D printed AF scaffolds were printed with 60 degree angle stripe patterned lamella structure(the inner-diameter is 5mm, outer-diameter is 10 mm and height is 3 mm). In the cytotoxicity test, the 3D printed AF scaffold showed good cell compatibility. The results of histological and immunohistochemical staining also showed the newly synthesized collagens and glycosaminoglycans, which are specific makers of AF tissue. And scaffold-free NP tissue actively synthesized glycosaminoglycans and type 2 collagen, which are the major components of NP tissue. When we combined two engineered tissues to realize the IVD, combined biphasic tissues showed a good integration between the two tissues. In conclusion, this study describes the fabrication of Engineered biphasic IVD tissue by using enable techniques of tissue engineering. This fabricated biphasic tissue would be used as a model system for the study of the native IVD tissue. In the future, it may have the potential to replace the damaged IVD in the future.

• Korean Chemical Engineering Research
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• v.55 no.1
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• pp.1-6
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• 2017

More addition of calcium carbonate in printing paper allows savings of the wood fibers and the drying energy. Pre-flocculation of GCC (ground calcium carbonate) using functional polymers was known as the best available technology to make high loaded paper until now, and it allowed less reduction of the paper essential properties such as tensile strength and smoothness at higher GCC content. However, pre-flocculated GCC became unstable in size under the continued agitation in the mill. Therefore, pre-flocculation method was modified in such a way that the in-situ calcium carbonate was formed between the GCC particles of the pre-flocculated GCC, and the resultant became more stable in size, which we named as HCC (hybrid calcium carbonate). HCC turned out to make high tensile strength and smoothness as much as the pre-flocculated GCC and gave much better size stability against stirring. Furthermore, HCC gave high bulk that pre-flocculation could not make.

• Journal of the Korean Society for Precision Engineering
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• v.31 no.12
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• pp.1067-1076
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• 2014

To date, biomedical application of three-dimensional (3D) printing technology remains one of the most important research topics and business targets. A wide range of approaches have been attempted using various 3D printing systems with general materials and specific biomaterials. In this review, we provide a brief overview of the biomedical applications using 3D printing techniques, such as surgical tool, medical device, prosthesis, and tissue engineering scaffold. Compared to the other applications of 3D printed products, the scaffold fabrication should be performed with careful selection of bio-functional materials. In particular, we describe how the biomaterials can be processed into 3D printed scaffold and applied to tissue engineering area.

• Journal of the Korean Society of Manufacturing Process Engineers
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• v.18 no.8
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• pp.1-7
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• 2019

Materials that can be used for 3D printing have been developed in terms of phase and functionality. Materials should also be easily printed with high accuracy. In recent years, the concept of 4D printing has been extended to materials whose physical properties such as shape or volume can change depending on the environment. Typically, such high-performance 3D printing materials include bio-inks and inks for sensors. This study deals with the optimization of the manufacturing method to improve the functional properties of the pressure sensitive material, which can be used as a sensor based on change of the resistance according to the pressure. Specifically, the number of milling for dispersion, the ratio of hardener for controlling elasticity, and the content of MWCNTs were optimized. As a result, a method of manufacturing a highly sensitive pressure-sensitive ink capable of use in 3D printing was introduced.