• 센서학회지
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• 제26권5호
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• pp.342-347
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• 2017

We present a precision instrument amplifier (IA) designed for bio-potential acquisition. The proposed IA employs a capacitively coupled instrument amplifier (CCIA) structure to achieve a rail-to-rail input common-mode range and low gain error. A positive feedback loop is applied to boost the input impedance. Also, DC servo loop (DSL) with pseudo resistors is adopted to suppress electrode offset for bio-potential sensing. The proposed amplifier was designed in a $0.18{\mu}m$ CMOS technology with 1.8V supply voltage. Simulation results show the integrated noise of $1.276{\mu}Vrms$ in a frequency range from 0.01 Hz to 1 KHz, 65dB SNR, 118dB CMRR, and $58M{\Omega}$ input impedance respectively. The total current of IA is $38{\mu}A$. It occupies $740{\mu}m$ by $1300{\mu}m$ including the passive on-chip low pass filter.

• 한국염색가공학회:학술대회논문집
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• 한국염색가공학회 2008년도 제39차 학술발표회
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• pp.131-132
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• 2008

Several squarylium dyes, derived from benzothiazole and indoles, were synthesized as a potential NIR dyes with absorption in the 700-900 nm region. These chromophores were induced much more bathochromic shift in the absorption maximum of the compound relative to the neutral parent squarylium dyes which we were described before. The squaryliums offer a convenient way of linking the dye to functional substrates and may be an advantage to be potential chromophores for NIR-absorbing, NIR-Cut-off filter, PDT(Photo Dynamic Therapy) materials.

• 한국군사과학기술학회지
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• 제27권4호
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• pp.516-527
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• 2024

Rapid, early, accurate detection and identification of the various pathogenic agents associated with the development of biological weapons is critical in preventing loss of life and limiting the impact of these organisms when used against civilian or military targets. The aim of this study was to produce a system for the simple, rapid, accurate and simultaneous detection and identification of Ricin, Botulinum toxin B and Staphylococcal enterotoxin B as a proof of principle for developing field appropriate reverse transcription loop-mediated isothermal amplification systems for the accurate identification of potential biological threats. These systems were designed to facilitate the identification of potential threats even in remote or resource-limited locations.

• 센서학회지
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• 제16권2호
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• pp.115-119
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• 2007

We report electrokinetic streaming potential detection in a microchannel. Streaming potential, one of the representative electrokinetic phenomena, becomes noticeable either when the channel size reduces or when the concentration of electrolyte reduces. We suggest a triangular-shaped microchannel to enhance streaming potential. The triangular-shaped microchannel shows better performance than the straight one in terms of streaming potential. Couple of possible methods to enhance streaming potential is also discussed. Moreover, this type of channel and phenomenon can be applied to biological sensor application and energy transduction.

• Bulletin of the Korean Chemical Society
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• 제30권4호
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• pp.857-862
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• 2009

We model lattice-mismatched group III-V semiconductor $In_{x}Ga_{1-x}$ alloys with the three-parameter anharmonic Kirkwood-Keating potential, which includes realistic distortion effect by introducing anharmonicity. Although the potential parameters were determined based on optical properties of the binary parent alloys InAs and GaAs, simulated dielectric functions, reflectance, and Raman spectra of alloys agree excellently with experimental data for any arbitrary atomic composition. For a wide range of atomic composition, InAs- and GaAs-bond retain their respective properties of binary parent crystals despite lattice and charge mismatch. It implies that use of the anharmonic Kirkwood-Keating potential may provide an optimal model system to investigate diverse and unique optical properties of quantum dot heterostructures by circumventing potential parameter searches for particular local structures.

• Bulletin of the Korean Chemical Society
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• 제35권11호
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• pp.3377-3380
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• 2014

• Bulletin of the Korean Chemical Society
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• 제34권2호
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• pp.689-691
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• 2013

• 한국식물생명공학회:학술대회논문집
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• 한국식물생명공학회 2006년도 한국육종학회 공동심포지엄 및 학술대회
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• pp.21.1-21.1
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• 2006

• 대한의용생체공학회:의공학회지
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• 제23권5호
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• pp.405-412
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• 2002

경락에서의 침구효과 원리는 침 자극이 인체의 저하된 기능상태로부터 각성상태, 응급상태, 국부적 쇼크 상태로 만들어줌으로써 인체의 전반적 생리기능이 새로운 평형을 이룰 수 있도록 하는데 있다. 그러나, 서양의학에서는 침구치료효과를 시술자의 생체에너지(기) 전달에 의한 효과보다는 단순한 침자극에 의한 신경-내분비-면역 계통의 작용과 반응으로 간주하고있다. 따라서 침구치료의 효과가 침 자극에 의한 경락의 작용임을 확인하고, 시술방법에 따른 전위 변화를 분석하기 위해서 경혈과 비경혈, 절연자침과 비절연자침, 보법과 사법으로 자극했을 때의 전위변화를 측정한 결과, 각각 다른 반응이 나타났다. 이는 동일 경락에서 침구의 작용효과는 단순한 침 자극에 의한 효과뿐만 아니라, 시술자의 생체에너지 전달에 의해 복합적으로 반응할 수 있음을 의미한다. 임상실험을 분석한 결과, 시술방법에 따른 경락에서의 전위 변화는 해당 경락의 허실과 해당장기의 건강상태에 따라 다르게 나타나고 있어서, 경락의 허실상태를 진단할 수 있는 진단 파라메터로서의 유의성을 확인하였다.

• Asian-Australasian Journal of Animal Sciences
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• 제22권4호
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• pp.483-491
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• 2009

In vitro produced porcine embryos have potential application in reproductive biotechnology. However, their development potential has been very low. This study evaluated the in vitro developmental ability and quality of cloned and parthenogenetic porcine embryos having 2-4 cells or 5-8 cells on Day 2 of in vitro culture. Analysis of results showed that 2 to 4 cell embryos had higher ability to form blastocysts than 5 to 8 cell embryos (p<0.05). Blastocysts produced from culture of 2 to 4 cell embryos also contained higher cell numbers and had lower BAX:BCLxL transcript ratio than those produced from 5 to 8 cell embryos (p<0.05), thereby suggesting 2 to 4 cell embryos have higher development potential. Further investigation revealed that 5 to 8 cell embryos had higher incidence (100${\pm}$0.0%) of blastomeric fragmentation than 2 to 4 cell embryos (15.2${\pm}$5.5% for parthenogenetic and 27.7${\pm}$7.1% for cloned embryos). This suggests that low development potential of 5 to 8 cell embryos was associated with blastomeric fragmentation. In conclusion, we have shown that morphological selection of embryos based on cell number on Day 2 of in vitro culture could offer a practical and valuable non-invasive means to select good quality porcine embryos.