• Title/Summary/Keyword: bio technology

Search Result 5,501, Processing Time 0.037 seconds

Schottky Barrier MOSFETs with High Current Drivability for Nano-regime Applications

  • Jang, Moon-Gyu;Kim, Yark-Yeon;Jun, Myung-Sim;Choi, Chel-Jong;Kim, Tae-Youb;Park, Byoung-Chul;Lee, Seong-Jae
    • JSTS:Journal of Semiconductor Technology and Science
    • /
    • v.6 no.1
    • /
    • pp.10-15
    • /
    • 2006
  • Various sizes of erbium/platinum silicided n/p-type Schottky barrier metal-oxide-semiconductor field effect transistors (SB-MOSFETs) are manufactured from $20{\mu}m$ to 10nm. The manufactured SB-MOSFETs show excellent DIBL and subthreshold swing characteristics due to the existence of Schottky barrier between source and channel. It is found that the minimization of trap density between silicide and silicon interface and the reduction of the underlap resistance are the key factors for the improvement of short channel characteristics. The manufactured 10 nm n-type SBMOSFET showed $550{\mu}A/um$ saturation current at $V_{GS}-V_T$ = $V_{DS}$ = 2V condition ($T_{ox}$ = 5nm) with excellent short channel characteristics, which is the highest current level compared with reported data.

Thermal behavior of Flame Retardant Filled PLA-WF Bio-Composites

  • Choi, Seung-Woo;Lee, Byoung-Ho;Kim, Hyun-Joong;Kim, Hee-Soo
    • Journal of the Korean Wood Science and Technology
    • /
    • v.37 no.2
    • /
    • pp.155-163
    • /
    • 2009
  • This study examined the thermal stability of PLA-WF bio-composites. Wood flour (WF)-filled PLA bio-composites were reinforced with the flame retardants, Melamine pyrophosphate (MPP), resorcinol bis (diphenyl phosphate) (RDP) and zinc borate (ZB). The flame retardant was compounded with PLA and natural biodegradable filler. The thermal properties of the biodegradable polymer and bio-composites reinforced with the flame retardant were measured and analyzed by DSC, DMA and TGA. The results showed that the flame retardant-reinforced biodegradable bio-composite exhibited improved thermal properties.

A Study on Development of Ubiquitous Bio-Sensors for Increasing Energy Efficiency (에너지 효용 증대를 위한 바이오 센서 개발에 관한 연구)

  • Han, Seung-Hoon
    • Journal of the Korean Solar Energy Society
    • /
    • v.28 no.6
    • /
    • pp.58-63
    • /
    • 2008
  • It is essential to investigate the structure and the main characteristic of Home USN (Ubiquitous Sensor Network) technologies in built ubiquitous environment while designing bio-sensors. For this study, Thermistor elements and Thermopile black body have been selected to implement ubiquitous technologies for bio-sensors and wireless network such as WiBro has been used to transfer sensing data to the BSN (Bio-Sensor Network) gateway. It is certain that efficiency of ubiquitous space design is improved if main components of each specific sensor network are analyzed precisely in digital way and corresponding communication modules are prepared accordingly. Ubiquitous technology, in conclusion, has to be applied not only with systematical mechanism or electronic setting but in human-centered atmosphere as well, keeping with deep consideration for bio-housing service factors in eco-friendly surrounding.

Status and Prospect of 3D Bio-Printing Technology (3D 바이오 프린팅 기술 현황과 응용)

  • Kim, Sung Ho;Yeo, Ki Baek;Park, Min Kyu;Park, Joung Soon;Ki, Mi Ran;Pack, Seung Pil
    • KSBB Journal
    • /
    • v.30 no.6
    • /
    • pp.268-274
    • /
    • 2015
  • 3D printing technology has been used in various fields such as materials science, manufacturing, education, and medical field. A number of research are underway to improve the 3D printing technology. Recently, the use of 3D printing technology for fabricating an artificial tissue, organ and bone through the laminating of cell and biocompatible material has been introduced and this could make the conformity with the desired shape or pattern for producing human entire organs for transplantation. This special printing technique is known as "3D Bio-Printing", which has potential in biomedical application including patient-customized organ out-put. In this paper, we describe the current 3D bio-printing technology, and bio-materials used in it and present it's practical applications.

Synthesis and Herbicidal Activities of Hydantoin Derivatives Possessing Amide Subgroup (아미드 치환체를 갖는 히단토인계 화합물의 합성과 제초활성 연구)

  • Ko, Young-Kwan;Chung, Keun-Hoe;Ryu, Jae-Wook;Woo, Jae-Chun;Koo, Dong-Wan;Choi, Jung-Sub;Kim, Jun-Young;Kim, Tae-Joon;Kwon, Oh-Yeon;Chung, Bong-Jin;Kim, Dae-Whang
    • The Korean Journal of Pesticide Science
    • /
    • v.10 no.2
    • /
    • pp.153-156
    • /
    • 2006
  • As an ongoing research program for the development of environmentally friendly new herbicide, several hydantoin derivatives 5a - 5i possessing amide subgroup were synthesized and shown to have interesting herbicidal activities exhibiting symptoms as Protoporphyrinogen IX oxidase inhibitor under postemergence upland greenhouse screening. Among derivatives tested, compound 5h showed superior herbicidal activity against upland problem weed, digitaria sanguinalis and aeschynomene indica to reference compound fluthiacet-methyl.

A Fusion Tag to Fold on: The S-Layer Protein SgsE Confers Improved Folding Kinetics to Translationally Fused Enhanced Green Fluorescent Protein

  • Ristl, Robin;Kainz, Birgit;Stadlmayr, Gerhard;Schuster, Heinrich;Pum, Dietmar;Messner, Paul;Obinger, Christian;Schaffer, Christina
    • Journal of Microbiology and Biotechnology
    • /
    • v.22 no.9
    • /
    • pp.1271-1278
    • /
    • 2012
  • Genetic fusion of two proteins frequently induces beneficial effects to the proteins, such as increased solubility, besides the combination of two protein functions. Here, we study the effects of the bacterial surface layer protein SgsE from Geobacillus stearothermophilus NRS 2004/3a on the folding of a C-terminally fused enhanced green fluorescent protein (EGFP) moiety. Although GFPs are generally unable to adopt a functional confirmation in the bacterial periplasm of Escherichia coli cells, we observed periplasmic fluorescence from a chimera of a 150-amino-acid N-terminal truncation of SgsE and EGFP. Based on this finding, unfolding and refolding kinetics of different S-layer-EGFP chimeras, a maltose binding protein-EGFP chimera, and sole EGFP were monitored using green fluorescence as indicator for the folded protein state. Calculated apparent rate constants for unfolding and refolding indicated different folding pathways for EGFP depending on the fusion partner used, and a clearly stabilizing effect was observed for the SgsE_C fusion moiety. Thermal stability, as determined by differential scanning calorimetry, and unfolding equilibria were found to be independent of the fused partner. We conclude that the stabilizing effect SgsE_C exerts on EGFP is due to a reduction of degrees of freedom for folding of EGFP in the fused state.

Melanin-concentrating Hormone-1 Receptor (MCH-1) Antagonism of the Leaves Extract from Morus alba

  • Oh, Byung-Koo;Oh, Kwang-Seok;Lee, Sung-Hou;Seo, Ho-Won;Choi, Yeon-Hee;Choi, Jae-Seok;Kim, Young-Sup;Lee, Byung-Ho;Kwon, Kwang-Il;Ryu, Shi-Yong
    • Natural Product Sciences
    • /
    • v.15 no.1
    • /
    • pp.27-31
    • /
    • 2009
  • The present study was performed to investigate the binding affinity of the ethanol extract from the leaves of Morus alba (EMA) and some EMA related plant materials (EMA-D, EMA-DM) for melanin-concentrating hormone-1 receptor (MCH-1) and also to examine the antagonistic effect of them for the recombinant MCH-1 receptor expressed in CHO cells. EMA, dichloromethane fraction (EMA-D) and EMA-DM exhibited high affinity for mammalian MCH receptor in receptor binding assays ($IC_{50}$ value: 2.3, 1.6 and $1.0{\mu}g/ml$, respectively). Other plant materials (MMA-D, MMA-DM) obtained from methanol extracts from the leaves of Morus alba (MMA) also exhibited high affinity for mammalian MCH receptor, even though the $IC_{50}$ values of them were lower than those of EMA-D and EMA-DM. In Chinese hamster ovary (CHO) cells expressing human MCH-1, EMA-DM and EMA-D significantly inhibited MCH-induced intracellular $Ca^{2+}$ increase ($IC_{50}$ values: 16.5 and $22.7{\mu}g/ml$, respectively). These results clearly indicate that the ethanol extract from the leaves of Morus alba (EMA) and some EMA related plant materials (EMA-D, EMA-DM) are novel selective MCH-1 receptor antagonist, respectively.