• Herbal Formula Science
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• v.10 no.2
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• pp.189-197
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• 2002

The inhibitory effects of ethanol extract of Radex Angelica uchiyamana, on LPS- or IFN- plus LPS-induced production of NO, and $TNF-{\alpha}$, and expression of iNOS and COX-2 were investigated in the activated RAW 264.7 cells. This extract significantly inhibited the production of NO and $TNF-{\alpha}$, and suppressed the expression of iNOS and COX-2 in a dose-dependent manner. These results show that ethanol extract of Radex Angelica uchiyamana may explain some known biological activities including anti-inflammatory effect, and is of considerable benefit in the treatment for NO and pro-inflammatory cytokine overproduction related immunological diseases.

• Journal of Korean Medical classics
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• v.34 no.2
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• pp.45-62
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• 2021

Objectives : To study the characteristics and meaning of the division pharmaceutical method in the Donguibogam through analysis of formulas that apply such method. Methods : Each formula applying the division method within the Donguibogam was analyzed Results & Conclusions : In the Donguibogam, medicinals to which the division pharmaceutical method was applied were baizhu[白朮], cangzhu[蒼朮], zhiqiao[枳殼], wuzhuyu[吳茱萸], xiangfuzi[香附子], chuanlianzi[川練子], huangbo[黃柏], etc. Formulas where this method was used were few, while the four methods that were used, together with the Center represents the principle of the five phases. The formulas that applied the division method usually did not adopt the tablet or decoction form, which means they were meant to treat slowly, treating deficiency or stagnation diseases due to problems in the middle-lower body such as the Spleen, Liver and Kidney. It could be said that compared to other more common formulas, this was a unique method. The division pharmaceutical method allows for usage of a wider variety of processing methods compared to single ingredient formulas, while there is lower chance of interference among the different types of processing. Another benefit is that the properties of the main medicinal ingredient could be preserved as much as possible. In addition, the division method allows for the main ingredient and the processed ingredient to interact exclusively, after which the processed medicinal is eliminated leaving only the main ingredient. This allows for maximum improvement of the main ingredient. The division method includes the principles of formula composition as well, whose concept could be positioned between single ingredient formulas and common formulas.

• Magazine of the Korean Society of Agricultural Engineers
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• v.11 no.3
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• pp.1742-1748
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• 1969

This is a method to determine the boundary line of reservoir flooding area which will be purchased. Until now, flood water level was used as the boundary line. By lowering this line from flood water level, purchasing cost of reservoir flooding area can be cut down. Sometimes, temporary flooding of arable land outside the boundary occurs. During the life of reservoir, flood damage to crop product on of this land must be indemified with net berefit from arable land between the bovndary line and normal water level. Following is the basic formula to determine the line. (Estimated flood damage to crop production of land outside the boundary line $\leqq$ Estimated net beneift from land between the boundary line and normal water level.) Minimum difference between both sides is needed to minimize the purchasing area. Flood damage and net benefit are estimated by hydrologic estimation with rainfall data and crop production estimation.

• Journal of Medicine and Life Science
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• v.18 no.1
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• pp.1-10
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• 2021

Omega-3 fatty acids (eicosapentaenoic acid [EPA] and docosahexaenoic acid [DHA]) may be beneficial for the primary and secondary prevention of cardiovascular events (CVEs), especially in patients with myocardial infarction or heart failure with reduced ejection fraction. For this purpose, one to two seafood meals per week is preferentially recommended. Omega-3 fatty acids with a high-dose EPA formula (4 g/day) may be more effective than EPA+DHA mixed supplements for the secondary prevention of CVE. Krill oil also contains omega-3 fatty acids, but at a much lower dose compared to fish oil. Supplemental vitamins and minerals have not shown the preventive effects on CVE in prospective, and randomized clinical trials, except for one Chinese study showing the stroke prevention effects of folic acid. The clinical benefit of chelation therapy in reducing CVEs is uncertain.

• Journal of Korean Society of Transportation
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• v.27 no.2
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• pp.199-206
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• 2009

In relation with economical efficiency analysis on investment evaluation of transportation system, among vehicle operating cost saving benefit that is applied to general preliminary assessment guidelines and investment evaluation guidelines, oil expense calculated data which concentrated and analyze on the relationship between oil consumption amount on running state and running speed. For uninterrupted flow which does not have stopped delay due to traffic signal, consideration for reduction benefit is possible due to the changes of running speed and travel time however, for interrupted flow which the stopping occurs due to signal control on actual signal intersection has no consideration for stopping delay time reduction and stopping rate improvement thus reflection of reality on improved effect analysis is difficult. Therefore, this research makes a framework to analyze benefits that reflects the features of signalized intersections by benefits associated with decrease of stopping delay time with existing research and developing vehicle operating cost calculation model formula. Vehicle operating cost has been redefined considering the stopping delay time by applying the oil consumption amount at idling and the economical benefit between conventional model and newly developed model when applied for the optimization of traffic signal system on the two roads in Seosan city has been analyzed comparative. While the importance of traffic system maintenance is being emphasized due to the increase of congested areas on roads, it is expected to assist in more realistic economical analysis which reflect the delay improvement through the presentation of an economic analysis model that considers the features of signalized intersections in signal optimization system improvements and effect analysis of congestion improvement projects`.

• Herbal Formula Science
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• v.10 no.2
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• pp.225-241
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• 2002

The inhibitory effects of Injinseulki including extracts of melanian snail plus phytomedicinal plants on $CCl_4$-induced fibrosis, $IFN-{\gamma}$ plus LPS-induced production of NO, PMA-stimulated production $O_2$, and tacrine-induced hepatic injury were investigated in rats, RAW 264.7 or HepG2 cells. The ethanol extracts of melanian snail significantly inhibited tarcrine-induced inury of HepG2 cells. Injinseulki inhibited the production of NO and $O_2$ in a dose-dependent manner in activated RAW 264.7 macrophages. Injinseulki significantly inhibited chemical-induced fibrosis in Rats. These results show that Injinseulki including extracts of melanian snail plus phytomedicinal plants may explain some known biological activities of Injinseulki including their anti-inflammatory and anti-fibrotic effect, and is of considerable benefit in the treatment for live diseases.

• KIEAE Journal
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• v.13 no.1
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• pp.9-15
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• 2013

This study aims to analyze, by forming an experimental area of artificial soil green area that is of equal scale and analyzing the characteristics of runoff water in accordance with the cross-section configuration, applied the benefits in an actual multi-housing case study complex. In examining the measurement test results of the runoff water infiltration amount and surface runoff amount of a low-profile type green area(Dish type) and a general type green area(Mound type), Dish type was seen to have 1.5-times higher runoff water infiltration amount than Mound type during heavy rainfalls and showed about a 50% reduction with respect to the surface runoff amount. In other words, artificial soil green area offers the benefit of reduction of surface runoff amount and suggests, in actuality even with a change to the cross-sectional configuration of artificial soil green area alone at the time of construction of multi-housings, the possibility of benefits and reduction of costs spent on existing rainwater management facilities.

• Pediatric Gastroenterology, Hepatology & Nutrition
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• v.22 no.4
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• pp.330-340
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• 2019

Human breast milk contains numerous biomolecules. Human milk oligosaccharides (HMOs) are the third most abundant component of breast milk, after lactose and lipids. Amongst the synthetized HMOs, 2'-fucosyllactose (2'-FL) and lacto-N-neotetraose (LNnT) are widely studied and are considered safe for infant nutrition. Several studies have reported the health benefits of HMOs, which include modulation of the intestinal microbiota, anti-adhesive effect against pathogens, modulation of the intestinal epithelial cell response, and development of the immune system. The amount and diversity of HMOs are determined by the genetic background of the mothers (HMO secretors or non-secretors). The non-secretor mothers secrete lower HMOs than secretor mothers. The breastfed infants of secretor mothers gain more health benefit than those of non-secretor mothers. In conclusion, supplementation of infant formula with 2'-FL and LNnT is a promising innovation for infant nutrition.

• Journal of the Institute of Electronics Engineers of Korea SD
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• v.47 no.6
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• pp.22-34
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• 2010

Existing image scalers generally adopt simple interpolation methods such as bilinear method to take cost-benefit, or highly complex architectures to achieve high quality resulting images. However, demands for a low power, low cost, and high performance image scaler become more important because of emerging high quality mobile contents. In this paper we propose the novel low power hardware architecture for a high quality raster scan image scaler. The proposed scaler architecture enhances the existing cubic interpolation look-up table architecture by reducing and optimizing memory access and hardware components. The input data buffer of existing image scaler is replaced with line memories to reduce the number of memory access that is critical to power consumption. The cubic interpolation formula used in existing look-up table architecture is also rearranged to reduce the number of the multipliers and look-up table size. Finally we analyze the optimized parameter sets of look-up table, which is a trade-off between quality of result image and hardware size.

• Journal of Sensor Science and Technology
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• v.29 no.5
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• pp.324-327
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• 2020

The impact of output conductance (g_o) on the short-circuit current-gain cut-off frequency (f_T) in In_0.8Ga_0.2As high-electron-mobility transistors (HEMTs) on an InP substrate was investigated. An attempted was made to extract the values of f_T in a simplified small-signal model (SSM) of the HEMTs, derive an analytical formula for f_T in terms of the extrinsic model parameters of the simplified SSM, which are related to the intrinsic model parameters of a general SSM, and verify its validity for devices with L_g from 260 to 25 nm. In long-channel devices, the effect of the intrinsic output conductance (g_oi) on f_T was negligible. This was because, from the simplified SSM perspective, three model parameters, such as g_{m_ext}, C_{gs_ext} and C_{gd_ext}, were weakly dependent on g_oi. However, in short-channel devices, g_oi was found to play a significant role in degrading f_T as L_g was scaled down. The increase in g_oi in short-channel devices caused a considerable reduction in g_{m_ext} and an overall increase in the total extrinsic gate capacitance, yielding a decrease in f_T with g_oi. Finally, the results were used to infer how f_T is influenced by g_oi in HEMTs, emphasizing that improving electrostatic integrity is also critical importance to benefit fully from scaling down L_g.