• 동의생리병리학회지
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• 제30권6호
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• pp.385-396
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• 2016

It is a fact that the existing pharmacological research method is difficult to explain the effect and mechanism of action of herbal formula of Korean medicine. We are now very pleased with the development of modern science and the development of a methodology for studying herbal formula characterized by network targets and multi-component therapeutics over the human body. In this review, systems pharmacology or network pharmacology is demonstrated how these are applied to explain the effectiveness of herbal medicine. The post-genomic era provides a unique opportunity for the two fields to understand and benefit from each other. In particular, recent research trends, research methodology, useful databases and results of research on herbal formula are introduced. China already has a policy of scientific development of traditional chinese medicine (TCM) and the development of Chinese medicine industry with a focus on herbal formula research at national level, and in Korea, it is urgent to support and nurture the methodology appropriate to the characteristics of the herbal formula in order to study the safety and efficacy of Korean medicine.

• Pediatric Gastroenterology, Hepatology & Nutrition
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• 제19권3호
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• pp.153-161
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• 2016

This paper covers algorithms for the management of regurgitation, constipation and infantile colic in infants. Anti-regurgitation formula may be considered in infants with troublesome regurgitation, while diagnostic investigations or drug therapy are not indicated in the absence of warning signs. Although probiotics have shown some positive evidence for the management of functional gastrointestinal disorders (FGIDs), the evidence is not strong enough to make a recommendation. A partially hydrolyzed infant formula with prebiotics and ${\beta}$-palmitate may be considered as a dietary intervention for functional constipation in formula fed infants. Lactulose has been shown to be effective and safe in infants younger than 6 months that are constipated. Macrogol (polyethylene glycol, PEG) is not approved for use in infants less than 6 months of age. However, PEG is preferred over lactulose in infants >6 months of age. Limited data suggests that infant formula with a partial hydrolysate, galacto-oligosaccharides/fructo-oligosaccharides, added ${\beta}$-palmitate may be of benefit in reducing infantile colic in formula fed infants in cases where cow's milk protein allergy (CMPA) is not suspected. Evidence suggests that the use of extensively hydrolyzed infant formula for a formula-fed baby and a cow's milk free diet for a breastfeeding mother may be beneficial to decrease infantile colic if CMPA is suspected. None of the FGIDs is a reason to stop breastfeeding.

• 한국소음진동공학회:학술대회논문집
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• 한국소음진동공학회 2008년도 추계학술대회논문집
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• pp.303-310
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• 2008

In Korea, the current noise impact assessment has not yet considered the vertical noise propagation property by buildings and other obstacles. And noise control plan has been established without conducting the economic assessment for the noise control facilities. A noise map is used to calculate the noise level based on a theoretical formula or an empirical formula, and also predict the characteristics of vertical propagation by linking with a geometry data. And It is Possible to analyze cost-effect of noise control facilities by consider installation costs. In this study, we addressed the application of noise map for noise impact assessment and cost-effect analysis of noise control facilities.

• 한국축산식품학회지
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• 제42권3호
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• pp.351-371
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• 2022

Milk fats are present as globules emulsified in the aqueous phase of milk and stabilized by a delicate membrane architecture called milk fat globule membrane (MFGM). The unique structure and composition of the MFGM play an important role in fat digestion and the metabolic programming of neonates. The objective of this review is to compare the structure, composition, and physicochemical characteristics of fat globules in human milk, bovine milk, and infant formula. It provides an overview of the fat digestion process and enzymes in healthy infants, and describes the possible roles of the MFGM in association with factors affecting fat digestion. Lastly, the health benefits of the MFGM on infant nutrition and future perspectives are discussed with a focus on brain development, metabolic response, and gut health.

• Pediatric Gastroenterology, Hepatology & Nutrition
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• 제21권1호
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• pp.28-33
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• 2018

Purpose: To evaluate the efficacy of synbiotic formula with partial whey hydrolysate and high magnesium content in infants presenting with functional constipation. Methods: Sixty-five infants with functional constipation were included. Forty infants were treated during one month with parental reassurance and the intervention formula and were compared to a control group of 25 infants treated with parental reassurance only. Parents completed a quality of life (QoL) questionnaire at baseline and during the last week of the study. Results: At inclusion, stool characteristics and QoL were similar in both groups. The control group was slightly older than the intervention group ($7.5{\pm}3.9$ vs. $6.2{\pm}3.6$ weeks). At onset, stool composition was "hard and tight" (Bristol stool scale 1 and 2) in all infants. After one month, stool composition remained unchanged in the control group except in two infants that developed "creamy" stools (Bristol stool scale type 3 and 4). In the intervention group, stools remained "hard and tight" in 27.5%, and became "creamy" in 47.5%, "loose" (Bristol stool scale type 5) in 22.5% and "watery" (Bristol stool type 6 and 7) in 2.5%. The benefit of the intervention formula was estimated to be "very important" in 70%. The median scores for QoL improved significantly in the intervention group for all parameters and for one in the control group. Conclusion: The intervention formula significantly improved functional constipation resulting in a better QoL of the parents and infants.

• 한국안전학회지
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• 제20권1호
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• pp.113-118
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• 2005

This study delivers the actual condition of investment for industrial accident prevention based on survey of 500 construction sites from 'reports far industry safety and health' published by Korea Occupational Safety & Health Agency (KOSHA). The various research techniques were used such as technical statistic analysis for construction industry, cost comparison of industrial accident prevention and accident loss. A formula was deduced to calculate accident loss and accident frequency by accident prevention cost through regression analysis.

• 대한안전경영과학회지
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• 제7권5호
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• pp.9-18
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• 2005

This study delivers the actual condition of investment for industrial accident prevention based on survey of 526 construction sites. The various research techniques were used such as technical statistic analysis for construction industry, construction and civil engineering works, cost comparison of industrial accident prevention and accident loss. A formula was deduced to calculate accident loss and accident frequency by accident prevention cost through regression analysis.

• 대한안전경영과학회지
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• 제7권5호
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• pp.19-30
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• 2005

This study delivers the actual condition of investment for industrial accident prevention based on survey of 526 construction sites. The various research techniques were used such as technical statistic analysis for construction industry, construction and civil engineering works, cost comparison of industrial accident prevention and accident loss. A formula was deduced to calculate accident loss and accident frequency by accident prevention cost through regression analysis.

• 응용통계연구
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• 제28권4호
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• pp.721-739
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• 2015

향후 고령사회에서 노후소득보장의 중요성은 소득양극화로 더 확대될 것으로 예상된다. 우리나라의 대표적 사회보장 제도인 국민연금은 대다수 국민들의 노후 소득보장과 함께 소득재분배를 담당하고 있다. Kim (2002), Kim 등 (2003), 그리고 Hong (2013) 등이 국민연금의 소득재분배 기능이 미흡할 수 있음을 보였지만 최근 Choi (2015)은 그 원인이 국민연금 기본연금액 산식의 구조적 취약점에 기인한다는 의견을 제기하였다. 본고는 현재 국민연금의 약 300만 노령연금수급자를 중심으로 개인별 이력자료와 2013 재정계산의 장기재정추계에서 관련 세대의 2014년 이후 수급에 대한 분석으로 국민연금 초기 수급자들의 생애순혜택에 의한 소득재분배 측정 결과를 제시하고 있다. 수급자 이력자료에 나타난 소득대체율로 측정한 소득재분배는 누진적이지만 그것은 초기 가입자들의 특성상 소득분위별 가입기간의 차이가 적기 때문인 것으로 설명된다. 남은 생애기간에 대한 급여를 장기재정추계 모형으로 보완하여 측정한 생애 순혜택은 크게 역진적으로 나타난다. 소득계층별 가입기간의 차이가 더 큰 이후 세대들에서는 그 역진성이 더 확대될 것으로 예상되어 국민연금의 소득재분배에 대한 재검토가 요청된다.

• 정보관리학회지
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• 제22권3호
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• pp.147-162
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• 2005

기업이나 연구소 등에서 운영하는 전문도서관의 경제적 가치 평가에 대한 필요성이 제기됨에 따라 본 연구는 전문도서관 주요 서비스의 가치평가에 대한 새로운 접근방법을 제시하였다. 선행연구의 이론과 모형에 타당성 평가를 통하여 본 연구에 적용할 편익측정요소와 분석방법을 도출하였으며, 적합성 평가는 보편타당성과 적용가능성을 기준으로 삼았다. 서비스에 어떤 유형의 자원(물적 자원 또는 인적 자원)이 사용되었는지에 따라 측정요소와 방법론을 달리 적용하였으며, 이를 토대로 전문도서관 주요 서비스의 가치평가를 위한 산출식을 제시하였다. 전문도서관 서비스의 경제적 가치평가를 위한 분석모형 개발은 서비스의 가치에 대한 객관적 입증이 가능해져서 전문도서관의 진정한 가치를 알릴 수 있는 계기가 될 수 있을 것으로 사료된다.