• Journal of Acupuncture Research
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• v.19 no.6
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• pp.184-192
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• 2002

Objective : This study is designed to find out the effects of Carthmi-Flos Herbal acupuncture therapy on shoulder pain. Methods : Under the assumption that Bee-venom Therapy may be effective for treatment seborrheic dermatitis, Bee-venom acupuncture was injected subcutaneously into the lesion including Gv24(神庭), Gv23(上星), Gv22, Gv20(白會), B4(供差), B5(五處), B6(承光), S8(頭維), etc. Results : 1. Female patients were 18 cases and these were more 12 cases than male patients. Fifty aged patients were the most(11 cases, 36.7%). 2. Below 1 month duration of disease was the most(14 cases 46.7%). 3. The effects of treatment by condition of patients was follows : After treatment, Grade IV was decreased 26.7%, Grade III was decreased 6.6% and Grade II was increased 23.3%. 4. The effects of treatment by Duration was follow : Below 1 month & 1 month to 6 month were improved highly. 5. In evaluating of satisfaction, exellent was 6 cases, and good was 19 cases. The percentage of above good was 83.3%. Conclusions : According to the results, Carthmi-Flos Herbal acupuncture may be good effects on the decrease of shoulder pain.

• Journal of Korean Medicine Rehabilitation
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• v.19 no.3
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• pp.47-67
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• 2009

Objectives : To research the trend of the study related to pharmacopuncture about musculoskeletal and nervous diseases in China and to make a comparison with clinical application on pharmacopuncture about musculoskeletal and nervous diseases in China and Korea. Methods : I reviewed and analyzed four Chinese Journals relating pharmacopucture from 2004 to 2008 and two Korean Journals relating pharmacopuncture from 1999 to 2008. Results : The following results were obtained in this study. 1. The pharmacopuncture was often used for diseases of spines and joints. 2. In the medicine of pharmacopuncture, Salviae Miltiorrhizae Radix, Angelicae Gigantis Radix were mainly used in China, and Bee-venom in Korea. 3. As a method of needling, local acupoint and Ashi-point were mainly ueed in both China and Korea. 4. In combined treatments, acupuncture, electronic acupuncture, Chuna, heating acupuncture were mainly used in China, and acupuncture, herb medicine, physiotherapy in Korea. 5. In the case of control group study, compared with other treatments pharmacopuncture was not verified the superiority of effectiveness in China, but in Korea, the effectiveness of a pharmacopuncture could be compared with that of others and the effectivenss of different pharmacopuncture could be compared. Conclusions : As seen above, in Korea, clinician should carry out clinical application about musculoskeletal and nervous diseases with various herbal injections besides Bee-venom. And I think that it will be starting point to use Salviae Miltiorrhizae Radix and Angelicae Gigantis Radix that were often used in China.

• The Journal of Churna Manual Medicine for Spine and Nerves
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• v.2 no.1
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• pp.59-67
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• 2007

Objective : Poly neuropathy is disease that reveals musle relaxation or sensory disorder, and Myopathy is disease that reveals musle weakness, wasting, pain. These diseases occur in the lower or upper limbs. This is the clinical report about Poly neuropathy or Myopathy estimated patients. Method : Patients were treated by acupuncture, herb medicine, bee venom herbal-acupuncture, moxibustion. We evaluated the improvement of symptoms with ROM(Range of Motion) and MCR(Medical Research Council) standard. Result : Symptoms that patients have at admission improved and disappered gradually with oriental medicine therapy. Observing the change of ROM and MCR standard, they indicated us improvement of disease. Conclusion : We achived a desirable result from treatment of peripheral neuropathy or myopathy estimated patients. However, further studies are required to prove the effect of oriental medicine treatment.

• The Journal of Internal Korean Medicine
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• v.39 no.2
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• pp.192-200
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• 2018

Objective: The purpose of this clinical study is to report the case of a 79-year-old man with weakness of the right lower limb due to postzoster femoral nerve palsy. Methods: A patient was treated with Korean medicine, including herbal medication, acupuncture, electro-acupuncture, and bee-venom, during 17 days of hospitalization. We evaluated the improvements of symptoms using manual muscle testing (MMT) and measuring the change in walking distance. Results: After 17 days of Korean medicine treatment, there was improvement in the patient's symptoms. MMT improved from 3- to 5, and walking distance improved from 2 spaces to 120 spaces. Conclusions: This study suggested that Korean medical treatment might be effective in the patient's recovery from postzoster femoral nerve palsy.

• Journal of Physiology & Pathology in Korean Medicine
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• v.26 no.6
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• pp.842-848
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• 2012

This study was performed to investigate the acupuncture & moxibustion therapy of the Wei symptom(痿證) in order to find out the clinical possibility. We investigated the acupuncture & moxibustion therapy of Wei symptom through six books published after 1993, searched sites as like 'Oasis', 'Pubmed', 'RISS', 'KISS', 'NDSL' and 'Google scholar'. Acupuncture & moxibustion prescriptions recorded in the orietal medicine literatures that were published before and after 1993 had a similar basis. Since 2000, in the clinical papers on the wei symptom searched from domestic journal, sa-am and dong's acupuncture therapy were mainly applied, but papers were confined in a case study. Since the mid-2000s, the clinical effectiveness of bee venom and electroacupuncture therapy on the wei symptom were uncovered, but the researches about the chracteristics in accordance with acupoints are more required. Since 2010, the mechanism of the bee venom and electroacupuncture on the wei symptom was revealed in animal experiments. On this basis, the systematic clinical studies beyond case paer or pilot study is(are) needed. The development of various treatment implements as like electroacupuncture, pharmacopuncture was required to access the incurable disease like wei syptom, and the efforts of providing evidence through systemic clinical trials are needed.

• Journal of Acupuncture Research
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• v.34 no.1
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• pp.39-48
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• 2017

Objectives : This study examined the effects of Korean medicine treatment in three patients following rotator cuff repair. Methods : Patients were treated with acupuncture, bee venom, moxibustion, and herbal medicine. Treatments were performed for an average of 3 weeks. A numeric rating scale (NRS) and range of motion (ROM) were used for evaluation of treatment effects. Results : The NRS score decreased and the ROM increased after treatment. In Case 1, the NRS score decreased from 10 to 6; flexion increased from $25^{\circ}$ to $180^{\circ}$ and abduction increased from $35^{\circ}$ to $180^{\circ}$. In Case 2, the NRS score decreased from 10 to 7; flexion increased from $30^{\circ}$ to $125^{\circ}$ and abduction increased from $15^{\circ}$ to $100^{\circ}$. In Case 3, the NRS score decreased from 10 to 3; flexion increased from $40^{\circ}$ to $120^{\circ}$ and abduction increased from $60^{\circ}$ to $95^{\circ}$. Conclusion : Korean medicine treatment following rotator cuff repair was effective in decreasing the NRS score and increasing ROM. Although the study only involved 3 cases, Korean medicine treatment may reduce the duration of rehabilitation.

• Korean Journal of Acupuncture
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• v.23 no.2
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• pp.19-27
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• 2006

Objectives: Although Korean Acupuncture (KA) in Korean Medicine (KM) shares its origins with Traditional Chinese Medicine (TCM), it has made its own contribution to the field of acupuncture and general medicine. This study reviews characteristics of KA. Methods: Representative theories of KA were reviewed in light of a constitutionally individualized and practically integrated approach. Individualized approach in KA is based on constitutional energy traits recognized in Saam, Taegeuk, and Eight Constitution acupuncture theories. New practically integrated therapeutic modalities, such as herbal, and bee venom acupunctures, have also been developed in KA. Results: As a form of natural medicine, KA along with KM put emphasis on the vitality and self-correcting mechanism of an individual, which led to the refinement of constitutional approach. KA along with KM theories features a summarized understanding and practical application of integrated therapeutics, which produced creative development of new modalities. Conclusions: KA is expected to make significant contributions to the individualized and practical medicine, based on basic research and clinical trials.

• Korean Journal of Acupuncture
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• v.28 no.1
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• pp.139-155
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• 2011

Objectives : To research trends of studies on treatments of knee osteoarthritis in Korean medicine. Methods : Domestic theses, published from 2000 to 2010, mentioning the treatments of knee osteoarthritis in Korean medicine were reviewed and analyzed. This study researched 79 theses and classified again according to the fields of the treatment. Results : The results were obtained as below ; 1. Studies on pharmacoacupuncture account for 41% of the total (32cases/79cases). The target of treatments had changed from pain alleviation and anti-inflammation to cartilage-protection since 2006. 2. Herbal Drug, Bee Venom, Cervi Cornu Parvum pharmacoacupuncture, Taping Therapy and Tai-Chi Exercise program were more effective than others. Moreover research on exercise program such as Tai-Chi has been increasing. 3. Some Herbal Drug (Glycyrrhizae Radix, Angelicae Gigantis Radix, Achyrantis Radix, Paeoniae Radix, Eucommiae Cortex and so on) were mainly used to investigate the effect on cartilage protection, pain relief and anti-inflammation in laboratory test. 4. Acupuncture including individualized, local acupoints and constitution acupuncture were effective than others in pain alleviation and symptom relief. 5. Pharmacoacupuncture Bee Venom were effective in recovery of joint function and pain relief while Buthus martensii Karsch, Homnis Placenta and Cervi Cornu Parvum were effective in cartilage protection and recovery. 6. Moxibustion was efficient to reduce joint pain and partly increase ROM (range of motion) of knee joint, but was not efficient to recover the function of knee joint. Conclusions : These results indicate that research trends on knee osteoarthritis were changed from symptomatic treatment (pain alleviation and anti-inflammation) to conservative treatment (cartilage protection and recovery).

• Journal of Acupuncture Research
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• v.23 no.2
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• pp.33-46
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• 2006

Alzheimer's disease (AD) is the most prevalent form of neurodegenerative disease associated with aging in the human population. This disease is characterized by the extracellular deposition of beta-amyloid peptide $(A{\beta})$ in cerebral plaques. $A{\beta}$ is derived from the ${\beta}-amyloid$ precursor protein (APP) by the enzymes, ${\beta}-$ and ${\eta}o-secretase$. Compounds that ${\beta}-$ or ${\eta}o-secretase$ inhibit activity, can reduce the production of $A{\beta}$ peptides, and thus have therapeutic potential in the treatment of AD. Increasing body of evidence has been demonstrated that Bee Venom(BV) Acupuncture could compete with complex protein involving in multiple step of $NF-{\kappa}B$ activation and exert the anti-inflammatory potential of combined inhibition of the prostanoid and nitric oxide synthesis systems by inhibition of IKK and $NF-{\kappa}B$. In this study, I investigated possible effects of BV on memory dysfunction caused by lipopolysaccharide (LPS) and $A{\beta}$ through inhibition of secretases activities and $A{\beta}$ aggregation. I examined the improving effect of BV on the LPS (2.5 mg/Kg, i.p.)-induced memory dysfunction using passive avoidance response and water maze tests in the mice. BV (0.84, $1.67\;{\mu}g/ml$) reversed the LPS-induced memorial dysfunction in dose dependent manner. BV also dose-dependently attenuated LPS-induced ${\beta}$ and ${\eta}o-secretase$ activities in cerebral cortex and hippocampus of the mice brain. This study therefore suggests that BV acupuncture method may be useful for prevention of development or progression of AD.

• Journal of Acupuncture Research
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• v.18 no.6
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• pp.161-170
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• 2001

목적 : 본 연구는 최근 임상에서 많이 사용하는 봉독약침액의 nitric oxide (NO)에 대한 소거효과를 분석하기 위하여 실행되었다. 방법 : 양성대조군으로 비타민과 실험군으로 국산 봉독과 미국산 봉독에 NO를 분비하는 S-nitroso-N-acetylpenicillamine (SNAP)을 투여한 후 NO의 농도를 540 nm 파장의 자외선 흡수량을 측정하여 평가하였다. 결과 : 국산 봉독은 $100{\mu}g/m{\ell}$에서 SNAP 처리 1.5, 3, 6 및 12시간에 대조군 (100%)과 비교하여 각각 $86.7{\pm}1.5,\;103.8{\pm}1.9,\;88.3{\pm}2.9$ 및 85.6{\pm}3.2%$의 잔류 NO 농도를 보였고, 1.5, 6 및 12시간에서 유의한 NO 소거 효과를 나타냈다. 미국산 봉독에서는 각각 $74.0{\pm}2.2,\;66.5{\pm}10.9,\;86.1{\pm}2.8$ 및 $59.1{\pm}3.8%$로 모든 시간에서 유의한 결과를 보였다. 결론 : 이상의 봉독의 NO 소거효과는 봉독 약침액이 임상에서 동통, 종창, 등에 치료에 사용하는 작용기전의 하나로 사료된다.