• Asian Pacific Journal of Cancer Prevention
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• 제17권6호
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• pp.2895-2899
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• 2016

Background: Increasing breast cancer (BC) incidence rates have been reported from India; causal factors for this increased incidence are not understood and diagnosis is mostly in advanced stages. Trivandrum exhibits the highest BC incidence rates in India. This study aimed to estimate trends in incidence by age from 2005-2014, to predict rates through 2020 and to assess the stage at diagnosis of BC in Trivandrum. Materials and Methods: BC cases were obtained from the Population Based Cancer Registry, Trivandrum. Distribution of stage at diagnosis and incidence rates of BC [Age-specific (ASpR), crude (CR) and age-standardized (ASR)] are described and employed with a joinpoint regression model to estimate average annual percent changes (AAPC) and a Bayesian model to estimate predictive rates. Results: BC accounts for 31% (2681/8737) of all female cancers in Trivandrum. Thirty-five percent (944/2681) are <50 years of age and only 9% present with stage I disease. Average age increased from 53 to 56.4 years (p=0.0001), CR (per $10^5$ women) increased from 39 (ASR: 35.2) to 55.4 (ASR: 43.4), AAPC for CR was 5.0 (p=0.001) and ASR was 3.1 (p=0.001). Rates increased from 50 years. Predicted ASpR is 174 in 50-59 years, 231 in > 60 years and overall CR is 80 (ASR: 57) for 2019-20. Conclusions: BC, mostly diagnosed in advanced stages, is rising rapidly in South India with large increases likely in the future; particularly among post-menopausal women. This increase might be due to aging and/or changes in lifestyle factors. Reasons for the increased incidence and late stage diagnosis need to be studied.

• 한국임상수의학회지
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• 제33권2호
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• pp.102-106
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• 2016

More than 20 years after the first report of porcine reproductive and respiratory syndrome virus (PRRSV) in Korea, the disease is still having major impact on domestic pig health and relevant industries. Although ELISA tests are commonly used by veterinarians to guide herd management, data on diagnostic performance of the test in field settings are very limited. The objective of this study was to evaluate two commercially available PRRSV ELISA (IDEXX PRRS X3 ELISA and Bionote PRRSV ELISA 4.0) to detect antibodies against PRRSV on serum samples. To this end, a total of 1,108 sera were recruited from 35 swine farms located in Gyeonggi province and tested at the Gyeonggi Province Veterinary Service Center. All tests were performed according to the manufacturer's instructions, by laboratory technicians who routinely perform PRRS testing on blood samples. Samples were collected from two sources of swine populations with different PRRS prevalence; 60 samples (5.4%) were originated from breeding farms and the remaining 1,048 samples (94.6%) were from farrow-to-finish farms. We applied Bayesian latent class model (LCM) for two-tests in the two-population when the accuracy of the gold standard is not available. The model estimated that Bionote ELISA was a bit more specific but slightly less sensitive. The estimated sensitivity and specificity of the IDEXX ELISA were 99.8% (95% CI 98.1-100%) and 86.4% (95% CI 81.4-96.5%), respectively. Sensitivity, specificity, positive predictive value and negative predictive value for Bionote kit were 98.7% (95% CI 92.8-100%), 89.8% (95% CI 86.2-93.1%), 93.8% (95% CI 91.5-96.0%), and 97.8% (95% CI 87.1-100%), respectively. Based on the Bayesian 95% credible intervals, the sensitivity and specificity of the two ELISAs were not significantly different each other when assuming that two kits were imperfect, indicating that two kits performed equally well in terms of sensitivity and specificity in our filed setting.

• 한국정보과학회:학술대회논문집
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• 한국정보과학회 2005년도 가을 학술발표논문집 Vol.32 No.2 (2)
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• pp.550-552
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• 2005

유비쿼터스 환경의 발달과 함께 모바일 장비에서 수집되어지는 컨텍스트 로그를 활용한 연구가 활발히 진행되고 있다. 하지만 기존의 컨텍스트 정보를 사용한 연구는 사용자 모델링에 그 초점을 맞추거나 단순하게 수집된 정보를 정리하여 한눈에 알아보기 쉽게 보여주는 정도에 그치고 있다. 본 논문에서는 사용자에게 새로운 서비스를 제공하기 위한 방법으로서 모바일 컨텍스트 로그와 외부 센서를 통해 정보를 수집하여 학습한 베이지안 네트워크를 이용하여 랜드마크를 찾아내는 예측 모델을 제안한다. 베이지안 네트워크 설계는 사전에 수집된 컨텍스트 정보를 요일과 주별로 분류하여 각각에 대한 베이지안 네트워크를 cross validation하여 랜드마크 예측에 대한 정확도를 평가하였다. 그리고 분류에서 가장 많이 사용하고 있는 SVM 방법을 사용하여 제안한 방법과의 성능을 비교평가하였다. 랜드마크 예측에 대한 정확도는 주간별로 설계한 베이지안 네트워크보다 요일별로 설계한 베이지안 네트워크가 랜드마크를 예측하는데 정화도가 높음을 확인하였고, 베이지안 네트워크를 사용한 방법이 SVM을 사용한 방법보다. 예측에 한 정확성이 우수하였다.

• 품질경영학회지
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• 제26권1호
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• pp.201-212
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• 1998

A methodology of the safety analysis on the fusion power plant is introduced. It starts with the understanding of the physics and engineering of the plant followed by the assessment of the tritium inventory and flow rate. We a, pp.y the probabilistic risk assessment. An event tree that explains the propagation of the accident is constructed and then it is translated in to an influence diagram, that is accident is constructed and then it is translated in to an influence diagram, that is statistically equivalent so far as the parameter updating is concerned. We follow the Bayesian a, pp.oach where model parameters are treated as random variables. We briefly discuss the parameter updating scheme, and finally develop the methodology to obtain the predictive distribution of time to next severe accident.

• 한국인터넷방송통신학회논문지
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• 제12권5호
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• pp.229-235
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• 2012

경제적인 국제화가 심화되어 세계경제가 통합화되는 환경에서 기업 및 개인, 금융기관 등의 외환거래 참가가들에게 외환거래로 인한 환위험의 회피방안이 무엇보다 절실하다. 이 방안을 마련하기 위하여 본 연구에서는 환율, 주가와 같은 시계열데이터의 모형추정에 적합한 은닉마아코프모델을 통해 단기 환율의 예측모형을 추정하고 이를 통해 향후 예측에 적용한다. 실제의 원/달러 환율데이터를 적용하여 최적의 모형이 추정된다면 이를 통해 향후의 일정기간의 운동양태의 예측이 가능할 것이다. 은닉마아코프모형의 추정을 위하여 베이지안정보기준을 통해 모형의 상태수를 정확하게 추정하는지를 확인하였으며 추정되는 모형으로 예측한 결과 실제 운동양태와 예측에 있어 두 곡선의 운동양태가 유사함을 확인하였다.

• 한국지형학회지
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• 제26권3호
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• pp.53-67
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• 2019

The purpose of this study is to identify the quality of landslide susceptibility in a landslide-prone area (Jinbu-myeon, Gangwon-do, South Korea) by spatial prediction modeling approach and compare the results obtained. For this goal, a landslide inventory map was prepared mainly based on past historical information and aerial photographs analysis (Daum Map, 2008), as well as some field observation. Altogether, 550 landslides were counted at the whole study area. Among them, 182 landslides are debris flow and each group of landslides was constructed in the inventory map separately. Then, the landslide inventory was randomly selected through Excel; 50% landslide was used for model analysis and the remaining 50% was used for validation purpose. Total 12 contributing factors, such as slope, aspect, curvature, topographic wetness index (TWI), elevation, forest type, forest timber diameter, forest crown density, geology, landuse, soil depth, and soil drainage were used in the analysis. Moreover, to find out the co-relation between landslide causative factors and incidents landslide, pixels were divided into several classes and frequency ratio for individual class was extracted. Eventually, six landslide susceptibility maps were constructed using the Bayesian Predictive Discriminant (BPD), Empirical Likelihood Ratio (ELR), and Linear Regression Method (LRM) models based on different category dada. Finally, in the cross validation process, landslide susceptibility map was plotted with a receiver operating characteristic (ROC) curve and calculated the area under the curve (AUC) and tried to extract success rate curve. The result showed that Bayesian, likelihood and linear models were of 85.52%, 85.23%, and 83.49% accuracy respectively for total data. Subsequently, in the category of debris flow landslide, results are little better compare with total data and its contained 86.33%, 85.53% and 84.17% accuracy. It means all three models were reasonable methods for landslide susceptibility analysis. The models have proved to produce reliable predictions for regional spatial planning or land-use planning.

• 한국정보통신학회:학술대회논문집
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• 한국정보통신학회 2012년도 추계학술대회
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• pp.547-549
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• 2012

경제적인 국제화가 심화되어 세계경제가 통합화되는 환경에서 기업 및 개인 금융기관 등의 외환 거래 참가자들에게 회환거래로 인한 환위험의 회피방안이 무엇보다 절실하다. 이 방안을 마련하기 위해서 본 연구에서는 환율, 주가와 같은 시계열데이터의 모형추정에 적합한 모델을 통해 단기 환율의 예측모형을 추정하고 이를 통해 향 후 예측에 적용한다. 실제의 환율 데이터를 통하여 최적의 모형이 추정된다면 이를 통해 향후의 일정기간의 운동양태의 예측이 가능할 것이다. 은닉마아코프모형의 추정을 위하여 베이지안정보기준을 통해 모형의 상태 수를 정확하게 추정하는지를 확인하였으며 추정되는 모형으로 예측한 결과 실제 운동양태와 예측에 있어 두 곡선의 운동양태가 유사함을 확인하였다.

• Animal Bioscience
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• 제37권4호
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• pp.622-630
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• 2024

Objective: Pig breeders cannot obtain phenotypic information at the time of selection for sow lifetime productivity (SLP). They would benefit from obtaining genetic information of candidate sows. Genomic data interpreted using deep learning (DL) techniques could contribute to the genetic improvement of SLP to maximize farm profitability because DL models capture nonlinear genetic effects such as dominance and epistasis more efficiently than conventional genomic prediction methods based on linear models. This study aimed to investigate the usefulness of DL for the genomic prediction of two SLP-related traits; lifetime number of litters (LNL) and lifetime pig production (LPP). Methods: Two bivariate DL models, convolutional neural network (CNN) and local convolutional neural network (LCNN), were compared with conventional bivariate linear models (i.e., genomic best linear unbiased prediction, Bayesian ridge regression, Bayes A, and Bayes B). Phenotype and pedigree data were collected from 40,011 sows that had husbandry records. Among these, 3,652 pigs were genotyped using the PorcineSNP60K BeadChip. Results: The best predictive correlation for LNL was obtained with CNN (0.28), followed by LCNN (0.26) and conventional linear models (approximately 0.21). For LPP, the best predictive correlation was also obtained with CNN (0.29), followed by LCNN (0.27) and conventional linear models (approximately 0.25). A similar trend was observed with the mean squared error of prediction for the SLP traits. Conclusion: This study provides an example of a CNN that can outperform against the linear model-based genomic prediction approaches when the nonlinear interaction components are important because LNL and LPP exhibited strong epistatic interaction components. Additionally, our results suggest that applying bivariate DL models could also contribute to the prediction accuracy by utilizing the genetic correlation between LNL and LPP.

• Steel and Composite Structures
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• 제47권6호
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• pp.759-779
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• 2023

The paper proposes two hybrid metaheuristic optimization and artificial neural network (ANN) methods for the close prediction of the ultimate axial compressive capacity of concentrically loaded concrete filled double skin steel tube (CFDST) columns. Two metaheuristic optimization, namely genetic algorithm (GA) and particle swarm optimization (PSO), approaches enable the dynamic training architecture underlying an ANN model by optimizing the number and sizes of hidden layers as well as the weights and biases of the neurons, simultaneously. The former is termed as GA-ANN, and the latter as PSO-ANN. These techniques utilize the gradient-based optimization with Bayesian regularization that enhances the optimization process. The proposed GA-ANN and PSO-ANN methods construct the predictive ANNs from 125 available experimental datasets and present the superior performance over standard ANNs. Both the hybrid GA-ANN and PSO-ANN methods are encoded within a user-friendly graphical interface that can reliably map out the accurate ultimate axial compressive capacity of CFDST columns with various geometry and material parameters.

• Tuberculosis and Respiratory Diseases
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• 제67권2호
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• pp.105-112
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• 2009

Background: Solitary pulmonary nodules (SPN) are encountered incidentally in 0.2% of patients who undergo chest X-ray or chest CT. Although SPN has malignant potential, it cannot be treated surgically by biopsy in all patients. The first stage is to determine if patients with SPN require periodic observation and biopsy or resection. An important early step in the management of patients with SPN is to estimate the clinical pretest probability of a malignancy. In every patient with SPN, it is recommended that clinicians estimate the pretest probability of a malignancy either qualitatively using clinical judgment or quantitatively using a validated model. This study examined whether Bayesian analysis or multiple logistic regression analysis is more predictive of the probability of a malignancy in SPN. Methods: From January 2005 to December 2008, this study enrolled 63 participants with SPN at the Kangnam Sacred Hospital. The accuracy of Bayesian analysis and Bayesian analysis with a FDG-PET scan, and Multiple logistic regression analysis was compared retrospectively. The accurate probability of a malignancy in a patient was compared by taking the chest CT and pathology of SPN patients with <30 mm at CXR incidentally. Results: From those participated in study, 27 people (42.9%) were classified as having a malignancy, and 36 people were benign. The result of the malignant estimation by Bayesian analysis was 0.779 (95% confidence interval [CI], 0.657 to 0.874). Using Multiple logistic regression analysis, the result was 0.684 (95% CI, 0.555 to 0.796). This suggests that Bayesian analysis provides a more accurate examination than multiple logistic regression analysis. Conclusion: Bayesian analysis is better than multiple logistic regression analysis in predicting the probability of a malignancy in solitary pulmonary nodules but the difference was not statistically significant.