• KSBB Journal
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• v.14 no.3
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• pp.284-290
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• 1999

Glucose fed-batch culture was studied to improve cellulose productivity by Acetobacter xylinum BRC5. When initial glucose concentrations in batch cultures were less than 20 g/L, yield coefficients of cellulose (Yp/s) remained a constant value of 0.21 g cellulose/g glucose. But a low yield coefficient, Yp/s=0.13 was obtained from an initial glucose concentration of 40 g/L. Since initial high glucose concentrations in batch culture resulted in low yields of cellulose, constant fed-batch cultures were carried out. The optimal feed rate for fed-batch culture was 2.22 g glucose/L.h. In constant fed-batch culture without DO control, 10 g/L of cellulose was obtained from 40 g/L of glucose with this feed rate, which was approximately two fold higher than that of the batch culture with the same initial glucose concentration. In DO stat plus fed-batch culture, the highest cellulose productivity could be obtained when dissolved oxygen level was controlled at 10% of air saturation, and cellulose productivity increased about 1.5 times compared with that of the culture without DO control.

• Proceedings of the Society of Korea Industrial and System Engineering Conference
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• 2002.05a
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• pp.387-396
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• 2002

Batch processes are a significant class of processes in the process industry and play an important role in the production of high quality speciality materials. Examples include the production of semiconductors, chemicals, pharmaceuticals, and biochemicals. With on-line sensors connected to most batch processes, massive amounts of data are being collected routinely during the batch on easily measured process variables such as temperatures, pressures, and flowrates. In this paper, multivariate SPC charts for on-line monitoring of the progress of new batches are developed which utilize the information in the on-line measurements in real-time. We propose the formation of statistical model which describes the normal operation of a batch at each time interval during the batch operation. An on-line monitoring scheme based on the proposed method can handle both cross-correlation among process variables at any one time and auto-correlation over time. And the control limits for the monitoring charts are established from sound statistical framework unlike previous researches which use the external reference distribution. The proposed charts perform real-time, on-line monitoring to ensure that the batch is progressing in a manner that will lead to a high-quality product or to detect and indicate faults that can be corrected prior to completion of the batch. This approach is capable of tracking the progress of new batch runs, identifying the time periods in which the fault occurred and detecting underlying cause.

• Bulletin of the Korean Space Science Society
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• 2008.10a
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• pp.34.2-34.2
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• 2008

The batch least square filter is widely used for ground estimations. However, in orbit determination (OD) under inaccurate initial conditions and few measurement data the performance by the batch least square filter can lead an unstable results. To complement weak part of the batch filter, the batch unscented transformation without any linearization process is developed by ACL (Astrodynamics and Control Laboratory) in YONSEI University. In this paper, the batch unscented transformation is introduced and applied to satellite orbit determination using Satellite Laser Ranging (SLR) data. Only range of the satellite measured from ground tracking stations is used for measurement data. The results of simulation test are compared with those of the weighted batch least square filter for various initial states errors (position and velocity). Simulation results show that the batch unscented transformation is comparable or slightly superior to batch least square filter in the orbit determination.

• Journal of the Korea Institute of Building Construction
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• v.13 no.6
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• pp.565-578
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• 2013

Batch production is common in repetitive construction projects, and it is not unusual for different batch sizes to be used by contractors in one project. While several scheduling methods, such as the Linear Scheduling Method (LSM) and the Repetitive Scheduling Method (RSM) have been proposed and used, no mathematical method for repetitive construction projects has been developed, and it is difficult to consider different batch sizes with the existing methods. An original mathematical algorithm for scheduling repetitive projects with different batch sizes is proposed in this study. This algorithm is illustrated with assumptions of resource continuity and single path in a project and introduces new terms, control batch and critical batch. The algorithm logics and mathematical equations are validated by comparison with the outcomes from a graphical scheduling approach through a simple and practical hypothetic project. As a result, it is expected that the proposed algorithm can be easily adapted and extended to computer software for scheduling, and can be a starting point for research on batch size management in repetitive construction projects.

• Journal of Korean Institute of Industrial Engineers
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• v.33 no.2
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• pp.246-253
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• 2007

All of the machines in a production line can be classified into bottleneck and non-bottleneck machines. A bottleneck is a resource whose capacity limits the throughput of the whole production facility. This paper addresses a batch sizing problem at the bottleneck machine. Traditionally, most batch sizing decisions have been made based on the EOQ (economic order quantity) model where setup and inventory costs are considered while throughput rate is assumed to be given. However, since batch size affects the capacity of the bottleneck machine, the throughput rate may not be constant. As the batch size increases, the frequency of the setup decreases. The saved setup time can be transferred to processing time, which results in higher throughput. But, the larger batch size may also result in longer lead time and larger WIP inventory level. This paper presents an alternative method to determine batch size at the bottleneck machine in a manufacturing line. A linear search algorithm is introduced to find optimal throughput rate and batch size at the same time. Numerical examples are provided to see how the proposed method works and to investigate the effects of some parameters.

• Biotechnology and Bioprocess Engineering:BBE
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• v.5 no.5
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• pp.340-344
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• 2000

Microbial oxidation of D-sorbitol to L-sorbose by Acetobacter suboxydans is of commercial importance since it is the only biochemical process in vitamin C synthesis. The main bottleneck in the batch oxidation of sorbitol to sorbose is that the process is severely inhibited by sorbitol. Suitable fed-batch fermentation designs can eliminate the inherent substrate inhibition and improve sorbose productivity. Fed-batch sorbose fermentations were conducted by using two nutrient feeding strategies. For fed-batch fermentation with pulse feeding, highly concentrated sorbitor (600g/L) along with other nutrients were fed intermittently in four pulses of 0.5 liter in response to the increased DO signal. The fed-batch fermentation was over in 24h with a sorbose productivity of 13.40g/L/h and a final sorbose concentration of 320.48g/L. On the other hand, in fed-batch fermentation with multiple feeds, two pulse feeds of 0.5 liter nutrient medium containing 600g/L sorbitol was followed by the addition of 1.5 liter nutrient medium containing 600g/L sorbitol at a constant feed rate of 0.36L/h till the full working capacity of the reactor. The fermentation was completed in 24h with an enhanced sorbose productivity of 15.09g/L/h and a sorbose concentration of 332.60g/L. The sorbose concentration and productivity obtained by multiple feeding of nutrients was found to be higher than that obtained by pulse feeding and was therefore a better strategy for fed-batch sorbose fermentation.

• Journal of Institute of Control, Robotics and Systems
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• v.18 no.3
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• pp.285-294
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• 2012

Using bearing measurement only, target motion state is not directly obtained so that TMA (Target Motion Analysis) is needed for this situation. TMA is a nonlinear estimation technique used in passive SONAR systems. Also it is the one of important techniques for underwater combat management systems. TMA can be divided to two parts: batch estimation and sequential estimation. It is preferable to use sequential estimation for reducing computational load as well as adaptively to target maneuvers, batch estimation is still required to attain target initial state vector for convergence of sequential estimation. Selection of batch time interval which depends on observability is critical in TMA performance. Batch estimation in general utilizes predetermined batch time interval. In this paper, we propose a new method called the BTIS (Batch Time Interval and Initial State Estimation). The proposed BTIS estimates target initial status and determines the batch time interval sequentially by using a bank of GMM-TS (Gaussian Mixture Measurement-Track Splitting) filters. The performance of the proposal method is verified by a Monte Carlo simulation study.

• Nuclear Engineering and Technology
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• v.56 no.3
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• pp.907-915
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• 2024

Various core designs with multi-batch fuel management (FM) are proposed and optimized for an innovative small modular reactor (iSMR), focusing on enhancing the inherent safety and neutronic performance. To achieve soluble-boron-free (SBF) operation, cylindrical centrally-shielded burnable absorbers (CSBAs) are utilized, reducing the burnup reactivity swing in both two- and three-batch FMs. All 69 fuel assemblies (FAs) are loaded with 2-cylindrical CSBA. Furthermore, the neutron economy is improved by deploying a truly-optimized PWR (TOP) lattice with a smaller fuel radius, optimized for neutron moderation under the SBF condition. The fuel shuffling and CSBA loading patterns are proposed for both 2- and 3-batch FM with the aim to lower the core leakage and achieve favorable power profiles. Numerical results show that both FM configurations achieve a small reactivity swing of about 1000 pcm and the power distributions are within the design criteria. The average discharge burnup in the two-batch core is comparable to three-batch commercial PWR like APR-1400. The proposed checker-board CR pattern with extended fingers effectively assures cold shutdown in the two-batch FM scenario, while in the three-batch FM, three N-1 scenarios are failed. The whole evaluation process is conducted using Monte Carlo Serpent 2 code in conjunction with ENDF/B-VII.1 nuclear library.

• Journal of Microbiology and Biotechnology
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• v.8 no.3
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• pp.203-207
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• 1998

Fed-batch fermentations with different feeding media were carried out in order to increase the productivity of invertase expression using a recombinant Saccharomyces cerevisiae containing plasmid pRB58. Two batch cultures showed the expression of the SUC2 gene at a low concentration of glucose, suggesting that glucose concentration could be used as a control variable in a fed-batch operation mode. In the fed-batch culture by feeding the basal medium, cell mass and specific invertase activity did not increase much as compared with the simple batch culture. A series of fed-batch cultures revealed that the sucrose-supplemented medium increased cell mass whereas the enriched medium did specific invertase activity. To capitalize on the synergism of the sucrose-supplemented medium and the enriched medium, the sucrose-supplemented enriched medium was used as a feeding medium. The fed-batch culture using this medium resulted in a 2.4-fold increase in cell mass and a 1.9-fold enhancement in specific invertase activity compared with those of the batch culture. The increase in cell mass and specific invertase activity led to a marked increase in total invertase activity, 250U/ml, which was 6.3 times higher than that of the batch culture.

• Journal of the Korea Institute of Information Security & Cryptology
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• v.20 no.1
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• pp.17-31
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• 2010

In VANET (Vehicular Ad hoc NETwork), vehicles can efficiently verify a large number of signatures efficiently using batch verification techniques. However, batch verification performed independently in each vehicle raises many redundant verification cost. Although, an RSU (Road Side Unit) can perform the batch verification as a proxy to reduce this cost, it additionally requires an efficient method to identify invalid signatures when the batch verification fails. In this paper, we analyze several ways of constructing a distributed batch verification system, and propose an efficient distributed batch verification system in which participating vehicles perform batch verification in a distributive manner for a small size signature set. In our proposed system, each node can report the batch verification result or the identified invalid signatures list and the RSU who received these reports can identify the invalid signatures and efficiently exclude them.