• Asian Pacific Journal of Cancer Prevention
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• 제17권1호
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• pp.353-356
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• 2016

Background: This study used receiver operating characteristic curve to analyze Surveillance, Epidemiology and End Results (SEER) for glassy cell carcinoma data to identify predictive models and potential disparities in outcome. Materials and Methods: This study analyzed socio-economic, staging and treatment factors. For risk modeling, each factor was fitted by a generalized linear model to predict the cause specific survival. Area under the receiver operating characteristic curves (ROCs) were computed. Similar strata were combined to construct the most parsimonious models. A random sampling algorithm was used to estimate modeling errors. Risk of glassy cell carcinoma death was computed for the predictors for comparison. Results: There were 79 patients included in this study. The mean follow up time (S.D.) was 37 (32.8) months. Female patients outnumbered males 4:1. The mean (S.D.) age was 54.4 (19.8) years. SEER stage was the most predictive factor of outcome (ROC area of 0.69). The risks of cause specific death were, respectively, 9.4% for localized, 16.7% for regional, 35% for the un-staged/others category, and 60% for distant disease. After optimization, separation between the regional and unstaged/others category was removed with a higher ROC area of 0.72. Several socio-economic factors had small but measurable effects on outcome. Radiotherapy had not been used in 90% of patients with regional disease. Conclusions: Optimized SEER stage was predictive and useful in treatment selection. Underuse of radiotherapy may have contributed to poor outcome.

• Asian Pacific Journal of Cancer Prevention
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• 제15권8호
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• pp.3699-3704
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• 2014

Background: This study aimed to determine knowledge, attitudes and believes about cervical cancer and human papilloma virus (HPV) vaccination with related factors in Turkish university students. Materials and Methods: This descriptive and cross sectional study was conducted between June-July 2013 in Hitit University located in Corum, a rural area to the East of Ankara. The population consisted of 550 university students who were training in first and last year from Faculties of Economics, Theology and Health. We reached 463 volunteer students without selection. The study of data was collected with a 44 item questionaire covering socio-demographic features, knowledge, attitudes and beliefs about cervical cancer, HPV and vaccination. Also for this study ethic committee report was taken from Bozok University. Data were evaluated with the SPSS 17.0 programme using the Ki kare test with P<0.05 accepted as statistically significant. Results: It was seen that there was a statistically significant variation between classrooms and departments of students with knowledge about cervical cancer and human papilloma virus and vaccine (p<0.001; p<0.01; p<0.05). Also we found low attitudes to thinking about taking HPV vaccination of girls and their children in the future. Conclusions: In light of the study findings; it was concluded that knowledge levels, beliefs and attitudes of the university students about cervical cancer, HPV infection and HPV vaccination were low.

• Asian Pacific Journal of Cancer Prevention
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• 제17권6호
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• pp.2883-2888
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• 2016

Background: Breast cancer (BC) is a serious lifestyle disease. There are several prognostic biomarkers like nuclear receptors whose over-expression is associated with BC characteristics. These biomarkers can be blocked by compounds with anti-cancer potential but selection must be made on the basis of no adverse side effects. This study is focused on finding of compounds from a plant source garlic. Materials and Methods: Twenty compounds from garlic and five targets considered involved in BC were retrieved from Pubchem database and Protein Data Bank respectively. They were docked using Accelrys Discovery Studio (DS) 4.0. The compounds which showed interaction were checked for drug likeliness. Results: Docking studies and ADMET evaluation revealed twelve compounds to be active against the targets. All the compounds displayed highly negative dock scores which indicated good interactions. Conclusions: The results of this study should help researchers and scientists in the pharmaceutical field to identify drugs based on garlic.

• 대한간호학회지
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• 제29권4호
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• pp.917-928
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• 1999

The purpose of this study was to explore the subjective opinions related to of smoking cessation behavior of smokers. The research period was from Nov. 1, 1998 to May. 7. 1999. The research method used was Q-methodology. The process of the research was as follows : 1. Collection of concourse The statement of self-reference was derived from face to face interviews with 15 adult smokers Statement were categorized by researcher according to semantics 2. Extraction of Q-sample 30 of the self reference statement from categories of the Q-population were selected. 3. Selection of P-sample 31 of smokers were selected by consideration of diversity in sociodemographic background. 4. Based on a 1 to 9 point scale, the selected university students were made to participate in Q-sorting. 5. Analysis of Q-type was obtained by use of the QUANAL program. The results of this study reavealed as follows : There are three type of smoking cessation behavior of Korean smokers. 1. The first type focused on one's own initiative to smoking cessation. 2. The second type focused on environmental factor related to smoking cessation. 3. The third type was habitual smoker. They adhere to smoke and are not ready to smoking cessation. It is suggested that the results of this study may contribute to the development strategies for the purpose of increasing the incidence of smoking cessation of smokers

• 대한정형도수물리치료학회지
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• 제24권1호
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• pp.39-46
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• 2018

Background: In most human lives, 80 percent have problems with the ankle and can be solved with a treatment that is objective in proper assessment. Discrepacts in the ankle are also associated with walking patterns and affect hip and knee joints. An evaluation of hip flexion and extensor muscles was performed to check the strength of hip joints after ankle sprain patients application of arthesis. Methods: In the hospital in Bucheon, 20 outpatients who visited the hospital for treatment with ankle sprain were tested with 10 male and 10 female patients. The criteria for selection of the study subjects were randomly divided into those with joint movement techniques applied to the ankle joints and those with conservative physical therapy. Results: In applying arthrography and preservation physical therapy to patients with ankle sprain, a difference in muscle strength between hip flexion and extensor was noted in post-evaluation comparisons. There were significant differences in the assessment of walking speed and walking time between the two counties in the gait analysis assessment (p<.05). Conclusion: Studies have shown that applying arthrography to people with ankle sprain has a greater therapeutic effect than using conservative physical therapy.

• 한국농촌건축학회논문집
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• 제5권3호
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• pp.22-33
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• 2003

I recognized necessity of the space planning to three-generation dwelling because of preservation of wholesome society sense of values of the younger generation indicated often to the point at issue by the change to nuclear family of present and by way to hand down thought of respect for the aged which is our traditional public morals. I wish to present basic data for storage space planning that resident's request and consciousness are reflected in such background. I investigated records in general concept, which is utilization pattern of storage space to achieve the function of these culture intermediation. The object of research is three-generation dwelling, such as 3L-K and 3L-DK as national residences that appear most generally in chongju city. The method of research was question investigation method to write utilization actual conditions and requirement of storage space directly. So I proposed suitable planning to resident's life style analyzing frequency, percentage and average distribution. When supply apartment house hereafter, it should be reflected wide selection by resident's characteristic and needed systematic storage space planning in consideration of user mainly. Also continuous and diversified researches that can improve quality of residence are required.

• 한국조경학회지
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• 제36권1호
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• pp.12-27
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• 2008

The purpose of this plan was to introduce the imaginary environment concept to modem environment design which was drawn by comparison of historic and cultural landscape. An area of $19,056m^2$ in I1-ja mountain water reservoir, located in 94 Dun-Chon-Dong, Gangdong-Gu, Seoul was selected for this planning. The concepts of Barrier-Free Design and Universal Design were introduced in order to accept the demands of various social classes. Based on the results of natural and cultural environment, Animism, Heaven, Earth and Man Theory and Yin-Yang and the Five Elements Theory these concepts were introduced for the philosophical background. Concept planning, topic selection, space planning and axis establishment were conducted during the framework step of the plan. Circulation planning, planting planning, facility and pavement planning, and light planning were conducted during the initial planning step. Lastly, detailed designing was performed for the major spaces. In addition, the imaginary environment concept was applied, ranging from the structural aspect of the space to designing factors of the facility in order to achieve placeness and practicality. In conclusion, this may be the first case design applying the imaginary environment concept to the environmental design with natural environment factors such as animals, plants, terrains and climate, and cultural such as cities, places, time, thoughts and symbols which are all factors to be considered in the existing environment design.

• 제어로봇시스템학회:학술대회논문집
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• 제어로봇시스템학회 2000년도 제15차 학술회의논문집
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• pp.493-493
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• 2000

Multi-valued decision making for transitional stochastic events was newly derived based on conditional probability of database. The two values (on-off) decision making method without transition had been proposed by one of the author in a previous work for a purpose of realizing human on-off decision making. The current method is an extension of the previous on-off decision making. By combining the conditional probability and the transitional probability, the closed form of the algorithm for the multi-valued transitional decision making was derived. The proposed multi-valued decision making was successfully applied to the determination of the five levels of the vigilance of a subject during the EEG recording; awake stage, drowsy stage and sleeping stages (stage 1, stage 2/3, REM (rapid eye movement)). The method for determining the vigilance level can be directly usable for the two purposes; selection of awake EEG segments for automatic EEG interpretation, and determination of sleep stages through sleep EEG. The proposed multi-valued decision making with a mathematical background of the probability can be applicable widely, in industries and in medical fields for purposes of the multi-valued decision making.

• Fisheries and Aquatic Sciences
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• 제20권6호
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• pp.8.1-8.18
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• 2017

Background: Metallothionein (MT) is a multifunctional protein playing important roles in homeostatic regulation and detoxification of metals. Mollusk species have been considered as useful sentinel platforms for MT-based biomarker approaches, and they have been reported to display an extraordinary structural diversity of MT proteins. However, potential diversity of molluskan MTs has not been fully explored and recent updates have suggested the need of revision of evolutionary hypothesis for molluskan MTs. Results: Based on bioinformatic analysis and phylogenetic evidences, novel divergence mechanisms and paths were hypothesized in both gastropod and bivalve MT groups. Our analyses are suggestive of the taxon- or lineage-specific domain multiplication/duplication from the ancestral or prototypic MT. Diversification and selection of molluskan MTs might be driven by the needs for acquiring metal selectiveness, specialized novel function, and improved capacity of metal detoxification under environmentally stressed conditions. Conclusion: The structural diversity and variations of molluskan MTs are significantly larger than previously understood. Undoubtedly, molluskan MTs have undergone dynamic divergent processes in their evolutionary histories, giving rise to the great diversity of domain structures in extant MT isoforms. Novel evolutionary paths for molluskan MTs newly proposed in this review could shed additional light onto the revision of the hypothesis for evolutionary differentiation of MTs in the molluskan lineage.

• 대한물리치료과학회지
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• 제27권2호
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• pp.88-95
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• 2020

Background: In the present study to investigate the immediate effects of standing position of the trunk stabilization exercise on Guillain-Barre syndrome patient's balance and gait abilities were examined. Design: Case report and conducted as a single-blind. Methods: Standing position of trunk stabilization exercise was conducted for five Guillain-Barre syndrome patient's who met the selection criteria were recruited. The subjects were conducted conservative exercise and trunk stabilization exercise. Conservative exercise was implemented for thirty min, five times for 8 weeks, and trunk stabilization exercise was implemented for 15 min. The participants' balance was measured via force plate (COP), functional reach test (FRT), timed up and go test (TUG), gait was measured using the 10 m walk test, and 6 minute walk test. Results: After training, the change values of the balance and gait ability in the subjects were significantly greater than pre-test. participants showed significant improvements in COP, FRT, TUG, 10 m walk test and 6 minute walk test pre and post the training (p<0.05). Conclusions: standing position of the trunk stabilization exercise was effective on Guillain-Barre syndrome patient's balance (COP, FRT, TUG) and gait (10 m walk test and 6 minute walk test) abilities were examined.