• Clinical Endoscopy
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• 제55권1호
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• pp.58-66
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• 2022

Background/Aims: Anastomotic leakage after esophageal surgery remains a feared complication. During the last decade, management of this complication changed from surgical revision to a more conservative and endoscopic approach. However, the treatment remains controversial as the indications for conservative, endoscopic, and surgical approaches remain non-standardized. Methods: Between 2010 and 2020, all patients who underwent Ivor Lewis esophagectomy for underlying malignancy were included in this study. The data of 28 patients diagnosed with anastomotic leak were further analyzed. Results: Among 141 patients who underwent resection, 28 (19.9%) developed an anastomotic leak, eight (28.6%) of whom died. Thirteen patients were treated with endoluminal vacuum therapy (EVT), seven patients with self-expanding metal stents (SEMS) four patients with primary surgery, one patient with a hemoclip, and three patients were treated conservatively. EVT achieved closure in 92.3% of the patients with a large defect and no EVT-related complications. SEMS therapy was successful in clinically stable patients with small defect sizes. Conclusions: EVT can be successfully applied in the treatment of anastomotic leakage in critically ill patients, while SEMS should be limited to clinically stable patients with a small defect size. Surgery is only warranted in patients with sepsis with graft necrosis.

• 자원환경지질
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• 제32권2호
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• pp.169-175
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• 1999

The water leakage of reservoir embankment usually occurs through water vein, which gives little influence on the embankment in a normal state. However, the embankment can be destroyed when the water level of reservoir increases with heavy rain in summer. Investigating the water vein and its path is therefore very important from the viewpoint of disater prevention and embankment protection. This paper presents survey results of one-meter-depth ground temperature and multi-point temperature logging in an embankment in Japan to delineate water veins and permeable formations. Four water veins have been predicted in the embankment by comparing measured one-meter-depth ground temperatures with the background ones which have no effect of water vein. The multi-point temperature logging was carried out in the borehole drilled at one of the predicted water veins. Depth and thickness of the permeable formation in the borehole can be determined from temperature restoration ratios with elapsed time. From these results we can find that the water leakage of reservoir embankment mainly occurs in sandy soil formation in the embankment.

• 자원환경지질
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• 제46권2호
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• pp.105-121
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• 2013

본 연구에서는 원격탐사, 전기비저항탐사, 전기전도도탐사(전자기탐사), 시추공 영상촬영법을 융합하여 효과적인 제방의 안정성 및 누수 평가 방법을 서산 A지구 방조제에 적용하여 제시하였다. Landsat ETM+열적외선 밴드를 사용하여 방조제 부근에서 다른 온도의 해수와 담수가 혼합되는 양상을 통해 누수의 존재, 규모 및 기간을 유추하였다. 전기비저항탐사를 방조제를 따라 실시하여 평균비저항 값 83.197 ${\Omega}$-m이하를 보이는 이상대의 수평적 수직적 분포를 확인하였다. 간조와 만조 시의 전기전도도 값의 분석을 통해 배경치의 영향을 최소화한 수평적 이상대 분포를 확인하였다. 시추공영상촬영을 통해 파쇄대의 수직적 분포양상과 기존 탐사법의 정확도를 확인하였다. 그 결과 전체 제방의 연장 중 41.7%에서 세 수평적 이상대 탐사법의 중첩구간이 확인되었으며, 시추공에서 확인된 수직적 파쇄양상을 고려할 때 누수구간이 제방단면의 중심부를 따라 상당부분 수평적으로 연장이 되어 방대한 양의 누수가 존재할 가능성이 높을 것으로 사료된다. 네 탐사법의 융합적 접근은 각 탐사방법이 가지고 있는 장점을 부각하고 단점을 보완하여 수평적 및 수직적인 누수구간과 기간의 확인 및 판별이 가능하고, 시추공에서 확인된 수직적 파쇄양상의 수평적 연장성을 예측하는데 높은 신뢰도를 보인다 할 수 있다.

• Journal of Radiation Protection and Research
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• 제46권3호
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• pp.127-133
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• 2021

Background: Phosphogypsum is material produced as a byproduct in fertilizer industry and is generally used for building materials. This material may contain enhanced radium-226 (²²⁶Ra) activity concentration compared to its natural concentration that may lead to indoor radon accumulation. Therefore, an accurate measurement method is proposed in this study to determine ²²⁶Ra activity concentration in phosphogypsum sample, considering the potential radon leakage from the sample container. Materials and Methods: The International Atomic Energy Agency (IAEA) phosphogypsum reference material was used as a sample in this study. High-purity germanium (HPGe) gamma spectrometry was used to measure the activity concentration of the ²²⁶Ra decay products, i.e., ²¹⁴Bi and ²¹⁴Pb. Marinelli beakers sealed with three different sealing methods were used as sample containers. Due to the potential leakage of radon from the Marinelli beaker (MB), correction to the activity concentration resulted in gamma spectrometry is needed. Therefore, the leaked fraction of radon escaped from the sample container was calculated and added to the gamma spectrometry measured values. Results and Discussion: Total activity concentration of ²²⁶Ra was determined by summing up the activity concentration from gamma spectrometry measurement and calculated concentration from radon leakage correction method. The results obtained from ²¹⁴Bi peak were 723.4 ± 4.0 Bq·kg^-1 in MB1 and 719.2 ± 3.5 Bq·kg^-1 in MB2 that showed about 5% discrepancy compared to the certified activity. Besides, results obtained from ²¹⁴Pb peak were 741.9 ± 3.6 Bq·kg^-1 in MB1 and 740.1 ± 3.4 Bq·kg^-1 in MB2 that showed about 2% difference compared to the certified activity measurement of ²²⁶Ra concentration activity. Conclusion: The results show that radon leakage correction was calculated with insignificant discrepancy to the certified values and provided improvement to the gamma spectrometry. Therefore, measuring ²²⁶Ra activity concentration in TENORM (technologically enhanced naturally occurring radioactive material) sample using radon leakage correction can be concluded as a convenient and accurate method that can be easily conducted with simple calculation.

• 한국정보처리학회:학술대회논문집
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• 한국정보처리학회 2020년도 춘계학술발표대회
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• pp.455-457
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• 2020

Recent studies demonstrate that deep learning model is easily biased by trained with unbalanced datasets. For example, the deep network can be trained to make a prediction by background feature instead the real target's feature. For those problem, a measurement called leakage was introduced to digitize this tendency. In this paper, we propose augmentation strategy which are used generally in computer vision problem to remedy this bias problem and we showed a simple augmentation methods have a effect to this task with experiments.

• Applied Microscopy
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• 제27권2호
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• pp.121-130
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• 1997

It has been demonstrated that majority of cells in the mammalian body such as myocytes and epithelial cells of skin and intestine respond to mechanical force or environmental factors and exhibit partial disruption of cell membrane, i. e., cell wounding, even in a physiological condition. Myocardial cells are rather apt to be wounded than other cells since they are definitely exposed to mechanical stress by contraction-relaxation and blood flow. However, the mechanism how myocardial cells protect themselves against cell wounding is not yet clarified. On this background, the present study was performed to elucidate whether albumin leakage is related to cell wounding and to assess whether diltiazem, a potent calcium channel blocker, is beneficial in isoproterenol-induced cell wounding in the heart. Hearts isolated from New Zealand White rabbits ($1.5\sim2.0kg$ body weight, n=20) were perfused with Tyrode solution by Langendorff technique. After stabilization of baseline hemodynamics, the hearts were subjected to bolus administration of isoproterenol and diltiazem as following order: $1.6{\mu}M$ isoproterenol at zero min (the beginning point): $16{\mu}M$ diltiazem at 20min; $1.6{\mu}M$ isoproterenol at 25min; $16{\mu}M$ isoproterenol at 45 min; $160{\mu}M$ diltiazem at 65 min; $16{\mu}M$ isoproterenol at 70 min. During all experiments, the left ventricular function was recorded, albumin leakage in the coronary effluents was analyzed by electrophoresis and Western blot, and myocardial cell membranes were examined by conventional transmission electron microscopy. Data were analyzed by t-test and linear regression test. Isoproterenol significantly increased the inotropic and chronotropic contractions, coronary flow, and frequency of arrhythmia, however, diltiazem did not influence on hemodynamics except decrease in the frequency of arrhythmia and a slight decrease in contractility. Isoproterenol also resulted partial disruption of myocardial cell membrane and inclose in albumin leakage, while diltiazem pretreatment showed number of electron-dense plaques in the cell membrane and a tendency of decrease in albumin leakage. These results indicate that albumin leakage may be an indirect index of cell wounding in the heart and diltiazem nay be beneficial to protect myocardial cells against isoproterenol-induced cell wounding. It is likely that diltiazem promotes resealing process of the cell membrane.

• Nuclear Engineering and Technology
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• 제56권3호
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• pp.893-899
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• 2024

In a secondary cooling system of a sodium-cooled fast reactor (SFR), rapid detection of hydrogen due to sodium-water reaction (SWR) caused by water leakage from a heat exchanger tube of a steam generator (SG) is important in terms of safety and property protection of the SFR. For hydrogen detection, the hydrogen detectors using atomic transmission phenomenon of hydrogen within Ni-membrane were used in Japanese proto-type SFR "Monju". However, during the plant operation, detection signals of water leakage were observed even in the situation without SWR concerning temperature up and down in the cooling system. For this reason, the study of a new hydrogen detector has been carried out to improve stability, accuracy and reliability. In this research, the authors focus on the difference in composition of hydrogen and the difference between the background hydrogen under normal plant operation and the one generated by SWR and theoretically estimate the hydrogen behavior in liquid sodium by using ultra-accelerated quantum chemical molecular dynamics (UA-QCMD). Based on the estimation, dissolved H or NaH, rather than molecular hydrogen (H₂), is the predominant form of the background hydrogen in liquid sodium in terms of energetical stability. On the other hand, it was found that hydrogen molecules produced by the sodium-water reaction can exist stably as a form of a fine bubble concerning some confinement mechanism such as a NaH layer on their surface. At the same time, we observed experimentally that the fine H₂ bubbles exist stably in the liquid sodium, longer than previously expected. This paper describes the comparison between the theoretical estimation and experimental results based on hydrogen form in sodium in the development of the new hydrogen detector in Japan.

• 한국재난관리표준학회지
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• 제2권3호
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• pp.39-46
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• 2009

소형루프 전자탐사는 지하매질의 전기비저항 분포를 비파괴적으로 영상화하는 효과적인 탐사방법이다. 하지만, 측정자료에 대한 정량적인 해석과 심도별 단면을 획득하기 위해서는 측정자료의 품질이 매우 중요하다. 본 연구에서는 소형루프 전자탐사 자료 획득 시 주변 배경잡음을 함께 측정하여 정량적 해석을 어렵게 하는 Bias noise를 제거하는 방법을 제시하였다. 이를 통해 잡음의 영향이 크게 감소한 신뢰성 있는 자료를 획득할 수 있었다. 이와 함께 측정자료로부터 전기비저항 영상을 간단하게 산출할 수 있는 겉보기 비저항 산출기법을 제시하였다. 본 연구에서 제시된 방법을 서로 다른 지하수위 조건을 가진 인공 모의지반 실험 사이트에 적용하였으며, 이를 통해 소형루프 전자탐사가 누수와 같이 지하수위 조건이 다른 지역을 탐지하는데 효과적인 방법임을 확인하였다.

• 한국환경농학회지
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• 제39권3호
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• pp.273-279
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• 2020

BACKGROUND: After transplanting, the recent abnormal low temperature caused physiological disorders of pepper seedlings. This study was conducted to evaluate the effects of UV-A LED, a physical elicitor, on the chilling tolerance of pepper seedlings. METHODS AND RESULTS: Seedlings were continuously irradiated with 370 and 385 nm UV-A LEDs with 30 W·m^-2 for 6 d. After that, seedlings were exposed to 4℃ for 6 h and then recovered under the normal growing condition for 2 d. There were no significant differences in growth characteristics of UV-A treatments compared to the control. Fv/Fm values of two UV-A treatments were below 0.8. Electrolyte leakage in the control was increased by chilling stress, while 385 nm UV-A had the significantly lowest value. Total phenolic content and antioxidant capacity of two UV-A treatments significantly increased due to UV-A radiation. However, total phenolic content and antioxidant capacity of the control increased due to chilling stress and tended to decrease again during the recovery time. CONCLUSION: We confirmed that UV-A light was effective to induce the chilling tolerance of pepper seedling, and the supplemental radiation of 385 nm UV-A LED before transplanting could be used as a cultivation technique to produce high quality pepper seedlings.

• 지질공학
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• 제4권2호
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• pp.219-229
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• 1994

균열 암반내 지하수 흐름은 공간적으로 불규칙하게 분포하는 균열 발달 상태에 영향을 받으므로 균질의 등방성 피압 대수층에 적용이 가능한 Theis식으로는 균열 암반 대수층의 수리지질학적 특성을 똑바로 이해할 수 없다. 본 연구에서는 지하수 흐름의 프락탈(Fractal)모델을 발전시킨 누수를 포함하는 프락탈모델의 이론적은 배경 및 수리상수 산출 방법을 제시하고,개발된 모델을 야외자료에 적용시켰다. 상기 모델은 홍천과 유성지역에서 수행된 양수시험 자료에 적용시킨 결과, 동일한 수리상수 값으로 양수정과 관측정에서의 관측된 수위하강 곡선과 이론적인 수위하강 곡선이 잘 일치하는 결과를 얻었다. 홍천 지역과 유성 지역의 시험공 주위의 프락탈 차원은 1.9로 구해졌으며, 이것은 이들 지역의 지하수 흐름이 2차원보다 약간 작은 프락탈 차원을 보인다는 것을 지시한다.