• 대한화장품학회:학술대회논문집
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• 대한화장품학회 2003년도 IFSCC Conference Proceeding Book II
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• pp.139-144
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• 2003

Using GC/MS and GC/Olfactmetry analysis, we identified two vinyl ketones such as 1-Octen-3-one (OEO) and cis-1, 5-Octadien-3-one (ODO) as key materials in axillary odor. OEO and ODO showed a strong metallic odor and low odor threshold. These two materials were occurred from the reaction of unsaturated long fatty acids in lipids and the iron ion in our body's metabolism. Then, it was recognized that Morus alba (Japanese name, Kuwa) extract, one of the plant extract, showed a very good effect to control the generation of these vinyl ketones due to its remarkable anti-oxidization effects.

• 대한화장품학회지
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• 제35권3호
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• pp.219-228
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• 2009

1.0 wt% triclosan과 0.4 wt% 죽염을 함유한 바디워시의 액취 등에 미치는 효과에 대한 연구를 위하여 in vitro 항균시험 및 무작위 배정, 이중맹검, 교차설계로 진행한 임상시험을 실시하였다. 1.0 wt% triclosan과 0.4 wt% 죽염을 함유한 바디워시는 Corynebacterium glutamicum, Corynebacterium xerosis, Corynebacterium jeikeium를 균주로 한 in vitro 항균 실험에서 모두 우수한 항균 효과가 있었다. 1.0 wt% triclosan과 0.4 wt% 죽염을 함유한 바디워시는 액취를 전반적으로 유의성 있게 감소시켰고 그 효과는 최소 9 h 동안 지속되었다. 1.0 wt% triclosan과 0.4 wt% 죽염을 함유한 바디워시는 액와 균수를 유의성 있게 감소시켰고 그 효과는 최소 9 h 동안 지속되었다. 임상시험 기간 동안 피시험자 전체에서 이상반응 증상은 나타나지 않았다. 결론적으로 1.0 wt% triclosan과 0.4 wt% 죽염을 함유한 바디워시는 액취에 대한 감소효과와 피부 안전성이 우수하였다.

• Archives of Plastic Surgery
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• 제39권2호
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• pp.143-149
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• 2012

Background : Axillary osmidrosis is characterized by an unpleasant odor, profuse sweating, and in some instances, staining of clothes that may socially and psychologically impair affected individuals. Various types of surgical procedures have been developed for the treatment of axillary osmidrosis. This study was undertaken to evaluate the effectiveness of subcutaneous pulsed neodymium: yttrium-aluminum-garnet (Nd-YAG) laser treatment for the treatment of axillary osmidrosis. Methods : Twenty-nine patients with axillary osmidrosis were included in this study. Patients were categorized according to the results of an axillary malodor grading system, and a subcutaneous pulsed Nd-YAG laser was applied to all patients. The treatment area for the appropriate distribution of laser energy was determined using the iodine starch test (Minor's test) against a grid pattern composed of $2{\times}2cm$ squares. The endpoint of exposure was 300 to 500 J for each grid, depending on the preoperative evaluation results. The results were evaluated by measurement of axillary malodor both pre- and postoperatively using the grading system and iodine starch test. Results : The average follow-up period was 12.8 months. Nineteen patients had a fair-to-good result and ten patients had poor results. The postoperative Minor's test demonstrated that there were remarkable improvements for patients with mild to moderate symptoms. Complications including superficial second degree burns (n=3) were treated in a conservative manner. A deep second degree burn (n=1) was treated by a surgical procedure. Conclusions : Subcutaneous pulsed Nd-YAG laser has many advantages and is an effective noninvasive treatment for mild to moderate axillary osmidrosis.

• 대한화장품학회:학술대회논문집
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• 대한화장품학회 2003년도 IFSCC Conference Proceeding Book II
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• pp.110-116
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• 2003

We have developed a high performance powder, which has a quenching efficacy not only for short-chain fatty acids and amines, but also for vinyl ketones (l-octen-3-one, cis-l,5-octadien-3-one), newly found as other key compounds in axillary malodor. By investigating various powders known to have a quenching efficacy, we finally developed a highly porous silica bead containing magnesium oxide. We found that the superior deodorant effect performed by this powder was the result of multiple effects due to both an excellent physical adsorption capability from its high porosity and a specific adsorption of vinyl ketones by magnesium in the powder. An antiperspirant formulation containing both this powder and a Morus alba extract showed good efficacy as a deodorant.