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뇌·신경과학 분야 연구결과의 임상 적용을 위한 방안 (Strategies for Clinical Application of Neuroscience Findings)

  • 조한별;김영훈;염아림;윤수정
    • 생물정신의학
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    • 제22권3호
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    • pp.113-117
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    • 2015
  • Psychiatry has progressed with neurobiological basis, providing individually tailored treatment, preventing mental illness, and managing public mental health. Foundational knowledge that may contribute to the development of psychiatry and neuroscience has been attained through continual national and international investment in research. However, this knowledge obtained from neurobiological research is not being applied to clinical practice proactively. This may be due to a lack of support for translational research connecting neuroscience with clinical practice, and a lack of development and availability of educational programs for clinical psychiatrists. To solve these problems, it is essential to support translational research conducted by clinicians and to establish an appropriate reward system. Considering the direction of progress in psychiatry and the demand from clinicians, appropriate investment in research and education programs that provide neurobiological knowledge applicable to clinical practice is required. Researchers and educators must also communicate and collaborate to deliver neurobiological findings effectively.

지반 그라우팅에 의한 상부구조물의 안전성 분석 (Stability Analysis of Upper Structures by Soil Grouting)

  • 황철성
    • 한국안전학회지
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    • 제28권4호
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    • pp.58-65
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    • 2013
  • Transportation and further expansion of social infrastructure was needed along the development of urbanization and population concentration. To use the underground space due to the lack of availability of land, it is inevitable to intersect between present structure and tunnel during construction. Soil grouting is one of the ground improvement methods to reinforce weak soil around the underground structures by injection of grouting liquid. Some of central columns of an upper structure are damaged during injection of grouting liquid by injection pressure. To investigate and improve the stability of the tunnel, three dimensional analysis are performed with full construction stages which includes the construction of present underpass, damaging columns of the underpass, reinforcing the columns by H-pile and shear walls, and excavation and construct tunnel. The arrangement of grouting holes such as curtain and horizontal type affects largely to the stability of upper structure and horizontal arrangement diminish the shear forces which is the cause of damage of central columns. The liquid injection type of reinforcement for tunnel is not recommended while the presence of upper structure with columns. Wall type reinforcing is utilize for permant support of upper structures which is affected by grouting injection pressure. H-pile is utilize for temporary support, but not for permanent since the sharing of shear forces is not much to shear wall during tunnel construction.

Introducing the Latest 3GPP Specifications and their Potential for Future AMI Applications

  • Koumadi, Koudjo M.;Park, Byong-seok;Myoung, Nogil
    • KEPCO Journal on Electric Power and Energy
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    • 제2권2호
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    • pp.245-251
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    • 2016
  • Despite the exponential throughput improvement in mobile communications systems, their ability to satisfy requirements of state-of-the-art and future applications of advanced metering infrastructure (AMI) is still under investigation. Challenges are mainly due to the inadequacy of third generation partnership project (3GPP) networks to support large amounts of devices simultaneously, while the number of AMI end-devices and the frequency of their data transmission increase with new AMI-based applications. In this introductory survey, innovative and future AMI applications and their communication requirements are first reviewed. Then, we identify challenges of 3GPP long term evolution (LTE) in enabling future AMI applications. More importantly, the latest improvements to LTE-A standard release 12 and 13 are reviewed and analyzed with regards to their potential to improve the quality of LTE-enabled AMI. It is found that 3GPP enhancements on machine type communications (MTC) standards will significantly enhance AMI communications. Beyond MTC specifications, non-MTC-specific enhancements such as carrier aggregation and multi-connectivity for user equipment will also contribute greatly to improving reliability and availability of AMI devices. The paper's focus is towards improved backhaul support for innovative and future AMI applications, beyond traditional automatic meter reading.

Nitric Oxide Donor 첨가가 구리 결핍 배아의 발달과 Nitric Oxide 하위 신호전달체계에 미치는 영향 (Effects of Nitric Oxide Donor Supplementation on Copper Deficient Embryos and Nitric Oxide-Mediated Downstream Signaling)

  • 양수진
    • Journal of Nutrition and Health
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    • 제41권8호
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    • pp.691-700
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    • 2008
  • 본 연구는 착상 후 단계의 쥐 배아와 난황낭을 대상으로 구리 결핍이 NO 하부 신호전달체계에 영향을 주는지를 알아보기 위한 것으로, 연구 결과는 다음과 같이 요약할 수 있다. 첫째, 구리 결핍은 정상적인 배아 및 난황낭 발달을 억제하고, NO의 생물학적 이용도와 아세틸콜린에 대한 NO dose-response를 낮추었다. 둘째, 구리 결핍은 NO의 하부 신호전달 물질인 cGMP 수준을 감소시켰으나, NO/cGMP 하부 신호전달체계 표적 중 하나인 P-VASP에는 영향을 미치지 않았다. 셋째, 구리 결핍 배양액에 NO donor를 첨가하는 것은 구리 결핍 배아와 난황낭의 기형 발생 빈도를 구리 정상군과 비슷한 수준으로 개선시켰다. 넷째, NO donor 첨가는 구리 결핍군에서 감소되었던 cGMP의 농도를 유의적으로 증가시켰지만, P-VASP에는 영향을 미치지 않았다. 상기 연구 결과들은 구리 결핍으로 인한 NO의 생물학적 이용도의 감소가 기형발생의 주요 발생 기전이라는 것을 뒷 받침하고 있다. 또한, 임상적으로 임신 기간 중 적절한 구리 섭취의 중요성을 강조한다.

Spatial and temporal trends in food security during the COVID-19 pandemic in Asia Pacific countries: India, Indonesia, Myanmar, and Vietnam

  • Yunhee Kang;Indira Prihartono;Sanghyo Kim;Subin Kim;Soomin Lee;Randall Spadoni;John McCormack;Erica Wetzler
    • Nutrition Research and Practice
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    • 제18권1호
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    • pp.149-164
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    • 2024
  • BACKGROUND/OBJECTIVES: The economic recession caused by the coronavirus disease 2019 pandemic disproportionately affected poor and vulnerable populations globally. Better uunderstanding of vulnerability to shocks in food supply and demand in the Asia Pacific region is needed. SUBJECTS/METHODS: Using secondary data from rapid assessment surveys during the pandemic response (n = 10,420 in mid-2020; n = 6,004 in mid-2021) in India, Indonesia, Myanmar, and Vietnam, this study examined the risk factors for reported income reduction or job loss in mid-2021 and the temporal trend in food security status (household food availability, and market availability and affordability of essential items) from mid-2020 to mid-2021. RESULTS: The proportion of job loss/reduced household income was highest in India (60.4%) and lowest in Indonesia (39.0%). Urban residence (odds ratio [OR] range, 2.20-4.11; countries with significant results only), female respondents (OR range, 1.40-1.69), engagement in daily waged labor (OR range, 1.54-1.68), and running a small trade/business (OR range, 1.66-2.71) were significantly associated with income reduction or job loss in three out of 4 countries (all P < 0.05). Food stock availability increased significantly in 2021 compared to 2020 in all four countries (OR range, 1.91-4.45) (all P < 0.05). Availability of all essential items at markets increased in India (OR range, 1.45-3.99) but decreased for basic foods, hygiene items, and medicine in Vietnam (OR range, 0.81-0.86) in 2021 compared to 2020 (all P < 0.05). In 2021, the affordability of all essential items significantly improved in India (OR range, 1.18-3.49) while the affordability of rent, health care, and loans deteriorated in Indonesia (OR range, 0.23-0.71) when compared to 2020 (all P < 0.05). CONCLUSIONS: Long-term social protection programs need to be carefully designed and implemented to address food insecurity among vulnerable groups, considering each country's market conditions, consumer food purchasing behaviors, and financial support capacity.

대학도서관 교수·학습지원 서비스에 대한 사서 인식분석 (Analysis of Librarians' Perception of Teaching and Learning Support Services of Academic Libraries)

  • 최예진;나민경;이지연
    • 한국문헌정보학회지
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    • 제57권2호
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    • pp.51-77
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    • 2023
  • 본 연구는 대학구성원의 교수·학습 활동을 위해 대학도서관에서 지원해야 하는 서비스의 방향성을 모색하기 위하여 교수학습센터와 대학도서관에서 제공하고 있는 교수·학습 관련 활동 현황을 파악하고, 대학도서관 사서를 대상으로 인터뷰를 통해 교수·학습 지원활동에 대한 인식을 분석하였다. 질적 데이터의 내용분석 결과, 도서관 서비스 영역에서는 교수·학습지원, 서비스 제공방식, 관계 강화와 관련된 실무자들의 인식을 파악할 수 있었으며, 도서관 역할 인식 영역에서는 도서관 역할에 대한 타 부서 인식, 도서관 역할 정립, 도서관 투자 확대로 나누어 이에 대한 실무자들의 인식을 파악할 수 있었다. 이에 본 연구에서는 대학도서관의 교수·학습지원 서비스의 방향성으로 '전공 및 학과 전담 서비스에 대한 홍보 강화', '교육자로서 사서의 역량 강화', '디지털 정보자원에 대한 리터러시 강화', '기초소양 함양 프로그램의 개발 및 운영에 있어 도서관의 역할 강화', '휴먼라이브러리의 운영', '도서관 공간의 다양한 활용 모색' 등을 제시하였다.

자치단체지역의 자연환경관리를 위한 보전지역 설정 (Conservation Area Designation Method for Natural Environmental Management in a Rural Local Government)

  • 이관규;성현찬;최재용
    • 한국환경복원기술학회지
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    • 제10권5호
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    • pp.1-9
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    • 2007
  • Local government with abundant natural resources should consider the nature conservation oriented planning process for the sustainable development. With this regard, the aim of this study is to provide a substantial methodology to support the decision-making process to designate the conservation areas. The objectives of the proposed methodology is to conserve natural resources in the local government's territory through quantitatively assessing the values of the natural resources based on various ecological factors such as topography, flora and fauna. In order to test the usability of the method, Gangneung City in Kangwon-Do is selected considering the latest data availability. Based on the assessment process land use of the subjected city could be categorized into 4 levels of conservative area, conservative level 1 area, conservative level 2 area, and conservative level 3 area. Among them, conservative area and conservative level 1 area could be combined as natural resources conservation area and the others could be regarded as buffer and transitional area. Especially conservation area is surrounded by conservation level 2 area. Conclusively, the GIS methods adopted in this could be the efficient illustrative tool to assess the local natural resource values with the central government established nature-environmental information systems.

Investigation of neural network-based cathode potential monitoring to support nuclear safeguards of electrorefining in pyroprocessing

  • Jung, Young-Eun;Ahn, Seong-Kyu;Yim, Man-Sung
    • Nuclear Engineering and Technology
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    • 제54권2호
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    • pp.644-652
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    • 2022
  • During the pyroprocessing operation, various signals can be collected by process monitoring (PM). These signals are utilized to diagnose process states. In this study, feasibility of using PM for nuclear safeguards of electrorefining operation was examined based on the use of machine learning for detecting off-normal operations. The off-normal operation, in this study, is defined as co-deposition of key elements through reduction on cathode. The monitored process signal selected for PM was cathode potential. The necessary data were produced through electrodeposition experiments in a laboratory molten salt system. Model-based cathodic surface area data were also generated and used to support model development. Computer models for classification were developed using a series of recurrent neural network architectures. The concept of transfer learning was also employed by combining pre-training and fine-tuning to minimize data requirement for training. The resulting models were found to classify the normal and the off-normal operation states with a 95% accuracy. With the availability of more process data, the approach is expected to have higher reliability.

Effect of Information Capital Readiness on Business Performance in Indonesian MSMEs: Does Online Market Orientation Matter?

  • TJAHJADI, Bambang;SOEWARNO, Noorlailie;GUNAWAN, Gabriella Monica
    • The Journal of Asian Finance, Economics and Business
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    • 제7권12호
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    • pp.267-274
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    • 2020
  • The focus of this study is to investigate the mediating role of online market orientation on information capital readiness-business performance relationship. The construct of information capital readiness is rarely researched. The readiness here refers to the availability of information capital needed to support strategy execution. As quantitative research, this study employs the partial least squares structural equation modeling (PLS-SEM) to test the hypotheses. Data was collected using questionnaires from the owners/managers of the micro, small, and medium-sized enterprises (MSMEs) in the East Java Province, Indonesia. As many as 433 respondents had participated. The result indicates that information capital readiness directly and positively affects business performance. Further analysis reveals that online market orientation partially mediates information capital readiness-business performance relationship. In conclusion, this study suggests that the owners/managers of the MSMEs should improve their information capital readiness to support online market orientation strategy so that it can improve their business performance. This is the first study that brings together the issues of information capital readiness and online market orientation as the antecedents of business performance in the Indonesian MSMEs research setting. The mediating role of online market orientation is rarely explored in previous studies.

OpenGL ES 2.0 API 기반 가변길이 명령어 설계 (Design of a Variable-Length Instruction based on a OpenGL ES 2.0 API)

  • 이광엽
    • 전기전자학회논문지
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    • 제12권2호
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    • pp.118-123
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    • 2008
  • 최근 Khronos에서 OpenGL ES 2.0 API 표준을 배포 하면서 임베디드 시스템의 그래픽 프로세서에서 능률적인 쉐이더 프로그램이 가능하게 되었다. 그 결과 모바일 기기에서도 OpenGL ES 2.0을 지원하는 그래픽 프로세서를 요구하게 되었다. OpenGL ES 2.0을 지원하기 위해서 명령어의 길이의 증가가 요구되고, 이는 메모리 용량의 증가를 초래한다. 본 논문에서는 효율적으로 명령어를 사용하는 새로운 명령어를 제안한다. 이 명령어는 가변 길이 방법과 유닛구조를 채택한 명령어 구조이다. 제안된 명령어 구조는 OpenGL ES 2.0 API를 지원하고 명령어 필드 낭비를 줄일 수 있도록 최대 4개의 32비트 유닛 명령어가 가변적으로 조합되어 수행된다.

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