• Proceedings of the Acoustical Society of Korea Conference
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• 1998.06c
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• pp.291-296
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• 1998

In the experiment carried out on 20 college students, recorded were frontal, temporal and occipital EEG, skin conductance response, skin conductance level, heart rate and respiration rate during listening to two music fragments with different affective valences and white noise administered immediately after negative visual stimulation. Analysis of physiological patterns observed during the experiment suggests that affective auditory stimulation with music is able to selectively modulate autonomic and cortical activity evoked by preceding aversive visual stimulation and to restore initial baseline levels. On other hand, physiological responses to white noise, which does not possess emotion-eliciting capabilities, evokes response typical for orienting reaction after the onset of a stimulus and is rapidly followed by habituation. Observed responses to white noise were similar to those specific to attention only and had no evidence for any emotion-related processes. Interpretation of the obtained data is considered in terms of the role of emotional and orienting significance of stimuli, dependence of effects on the background physiological activation level and time courses of attention and emotion processes. Physiological parameters are summarized with regard to their potential utility in differentiation of psychological processes induced by auditory stimuli.

• Proceedings of the Korean Society for Emotion and Sensibility Conference
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• 2001.11a
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• pp.91-95
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• 2001

In this study, we estimated the behavior of the diversity of physiological responses under varied physical environmental factors by measuring variations of heart rate variability (HRV), an index of activity of cardiac autonomic control. Seven healthy young male adults consented and participated in the study. The environmental conditions consisted of thermal, lighting, and acoustic conditions. Two components of HRV were measured. one was the low frequency (LF) component of HRV, which provided a quantitative index of the sympathetic and parasympathetic (vagal) activities controlling the heart rate (HR). The other component measured was the high frequency (HF) component, which provided an index of the vagal tone. The percent contribution of physical environmental factors to the variations in HRV indices were calculated by ANOVA. The contribution of physical environmental factors to the variations in HR was higher than the contribution of HF and LF. However, the contribution of these factors was lower than the contribution related with individual difference in all indices. This result showed that the individual diversity of physiological responses is not a negligible quantity.

• Science of Emotion and Sensibility
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• v.11 no.4
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• pp.637-644
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• 2008

Human emotion has been tried to be recognized by physiological measurements in developing emotion machine enabling to understand and react to user's emotion. This study is to find the time-dependent physiological measurements and their variation characteristics for discriminating emotions according to dimensional emotion model. Ten university students were asked to watch sixteen prepared images to evoke different emotions. Their subjective emotions and autonomic nervous responses such as ECG (electrocardiogram), PPG (photoplethysmogram), GSR (Galvanic skin response), RSP (respiration), and SKT(skin temperature) were measured during experiment. And these responses were analyzed into HR(Heart Rate), Respiration Rate, GSR amplitude average, SKT amplitude average, PPG amplitude, and PTT(Pulse Transition Time). TDPs(Time dependent parameters) defined as the delay, the activation, the half recovery and the full recovery of respective physiological signal in this study have been determined and statistically compared between variations from different emotions. The significant tendencies in TDP were shown between emotions. Therefore, TDP may provide useful measurements with emotion recognition.

• The Journal of Korean Medicine
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• v.38 no.3
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• pp.1-12
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• 2017

Objectives: To interpret the meanings of Ryodoraku data and to use it as diagnosis tool, study on relationship between Ryodoraku and autonomic nervous reaction (ANR) has to be preceded prior to disease studies. This study aims to observe the change of Ryodoraku characteristics with ANR caused by treadmill exercise via a feasibility study. Methods: The electric current at 24 Ryodoraku points(H1~H6 at left/right wrists and F1~F6 at left/right feet) and vital signs were measured at rest, immediately after the treadmill exercise test, and at later recovery times(10min, 20min, 30min, 60min, 120min after the exercise test). The calculated Ryodoraku scores (RSs) were analyzed using repeated ANOVA test. Results: The RSs in the wrist Ryodoraku points were significantly increased immediately after the exercise (p<.05) and at 10min recovery time (p<.01), and no significant differences were found during the rest of the experimental sets. To the contrary, the RSs in the feet Ryodoraku points showed less difference throughout all the measurement time. Conclusions: The Ryodoraku characteristics change more sensitively in the wrists than in the feet in accordance with the previously reported sweat gland responses of the treadmill exercise. This is the first feasibility study to observe the change of Ryodoraku characteristics caused by treadmill exercise, and it shows the Ryodoraku characteristics are in accordance with known ANS responses.

• Journal of Korean Biological Nursing Science
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• v.17 no.2
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• pp.159-168
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• 2015

Purpose: The purpose of this study was to determine the effects of auricular acupressure on menstrual pain, difficulties in daily life, negative feelings and autonomic nervous responses among college students. Methods: A Randomized Controlled Trial design was used. The treatment group A (n=12) receivedauricular acupressure therapy on the first or second day of their menstrual period. Treatment group B (n=18) regularly received an auricular acupressure therapy once a week for a month. The control group (n=19) received no auricular acupressure therapy. An independent t-test was used to examine pre-post test differences in the group. The ANOVA and Scheffe test were used to examine pre-post test differences among the group. Results: Subjects in treatment group A showed significantly less menstrual pain, difficulties in daily life, and negative feelings than the control group did. The participants in treatment group B also showed significantly less difficulties in daily life and negative feelings than the control group. Conclusion: The findings support that auricular acupressure therapy on menstrual periods is effective in controlling menstrual pain, difficulties in daily life, and negative feelings. As the method is simple, it would be useful for female students to learn to use this method to alleviate the symptoms related to menstruation through self care.

• Journal of Life Science
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• v.34 no.5
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• pp.320-332
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• 2024

The aims of this study were to compare the differences in hemodynamics between cigarette smoking and using heated tobacco products (HTPs) and to determine the acute effects of using HTPs on cardiac autonomic regulation. Another goal was to examine the acute cardiac autonomic responses when using different tobacco sticks in HTPs. Sixteen healthy male smokers completed an open-label, randomized, crossover trial consisting of non-smoking (NS), cigarette smoking, and the use of two different HTPs (IQOS with HEETS; lil SOLID with Fiit). Sub-trials, which included NS, lil SOLID with Fiit, and lil SOLID with HEET, were performed on eight smokers among the total subjects. Hemodynamic variables, such as systolic blood pressure (SBP) and diastolic blood pressure (DBP), and heart rate variability were measured before, during, and 30 minutes after using each tobacco product. Using HTPs resulted in a significant increase in both SBP and DBP, comparable to smoking cigarettes. Cardiac sympathetic activity significantly increased, and cardiac vagal tone (CVT) significantly decreased after acute exposure to HTP aerosol, similar to the effects of cigarette smoke exposure. Furthermore, differences in the withdrawal of CVT were observed when using different tobacco sticks in the same HTPs. The findings of this study indicate that acute exposure to HTP aerosol increases the hemodynamic burden and disrupts cardiac autonomic balance, similar to exposure to cigarette smoke. Moreover, depending on the type of tobacco stick inserted into the HTP device, acute withdrawal of CVT may have been enhanced.

• Biomedical Science Letters
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• v.13 no.2
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• pp.119-125
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• 2007

It is widely known that protein tyrosine kinases (PTKs) are involved in controlling many biological processes such as cell growth, differentiation, proliferation, survival and apoptosis. An $\alpha3\beta4$ subunit combination acts as a major functional acetylcholine receptor (nAChRs) in male rat major pelvic ganglion (MPG) neurons, and their activation induces fast inward currents and intracellular calcium increases. Recently it has been reported that the activity of acetylcholine receptors (AChRs) in some neurons can be negatively regulated by PTKs. However, the exact mechanism of regulation of nAChRs by PTKs is poorly understood. Therefore, we examined the potential role particular in nAChR by PTK using electrophysiology and calcium imaging in male rat MPG neurons. ACh induced inward currents and $(Ca^{2+})_i$ increases in MPG neurons, concomitantly. These responses were inhibited by more than 90% in $Na^+$- or $Ca^{2+}$- free solution. $\alpha$-conotoxin AuIB, a selective $\alpha3\beta4$ nAChR blocket, inhibited ACh-induced inward currents. Genistein (10 $\mu$M), a broad-spectrum tyrosine kinase inhibitor, markedly decreased ACh-induced currents and $Ca^{2+}$ transients, whereas 10 $\mu$M genistin, an inactive analogue, had little effect. Overall these data suggest that the activities of $\alpha3\beta4$ AChRs in MPG neurons are positively regulated by PTK. In conclusion, trosine kinase may be one of the key factors in the regulation of $\alpha3\beta4$ nAChRs in rat MPG neurons, which may play an important roles in the autonomic neuronal function such as synaptic transmission, autonomic reflex, and neuronal plasticity.

• Journal of the Ergonomics Society of Korea
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• v.21 no.3
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• pp.35-46
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• 2002

In this study, emotion changes were induced by four imaginations- pleasantness, unpleasantness, arousal, relaxation and it was examined using subjective evaluation and analysis of the physiological signals of the central and autonomic nerve systems whether the intended emotions were appropriately achieved, and whether these emotion changes could be distinguished from the analysis of physiological signals. Each of the four imaginations was implemented on 32 subjects for 30 seconds, while that Electroencephalogram (EEG), Eelectrocardiogram (RSP) were measured, and a subjective evaluation was implemented following the completion of the measurement. The analysis of the subjective evaluation revealed that the subjects underwent the four clearly differentiated imaginations, and the pleasantness level was classified into four imagination stages, pleasantness>relaxation>arousal=comfort>unpleasantness, and arousal level was classified into four imagination stages in the order of arousal>unpleasantness${\approx}$pleasantness>comfort>relaxation. The analysis of the EEG revealed that three stages of pleasantness level, pleasantness>relaxation=arousal=comfort>unpleasantness were classified from the values of ${\alpha}/{\alpha}+{\beta}\;and\;{\beta}/{\alpha}+{\beta}$, and about tour distinguishable stages of arousal level were obtained from the autonomic nervous system responses following the order of arousal>unpleasantness${\approx}$pleasantness> comfort> relaxation. It was found that intended emotion could be induced from the imagination, and these induced emotion changes could be differentiated using the physiological signals of the EEG and autonomic nervous system.

• Journal of Korean Traditional Oncology
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• v.16 no.1
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• pp.15-31
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• 2011

Objective : The study aims to investigate the effect of moxibustion treatments on autonomic nervous system function of cancer patients through the evaluation of heart rate variability (HRV) biofeedback testing. Materials and Methods : Six cancer patients from inpatient care unit of Dunsan Oriental Hospital, Daejeon University were given three moxibustion treatment sessions every other day over one week period on five Oriental Medicine meridian points CV4, CV6, CV12, KD1, and PC8. HRV biofeedback was conducted before and after each treatment sessions. Three areas of analyses were done from the test conducted; Time Domain Analysis, Frequency Domain Analysis and Autonomic Nervous System (ANS) balance analysis. Results : Time Domain Analysis has shown increased Standard Deviation of all Normal R-R Intervals (SDNN), and decreased Mean Heart Rate and Physical Stress Index (PSI) levels, with statistical significance (P<0.05). In Frequency Domain Analysis, series of moxa treatments have increased Total Power (TP), Very Low Frequency Oscillation Power (VLF), High Frequency Oscillation Power (HF), normalized HF values while decreasing Low Frequency Oscillation Power (LF), normalized LF and LF/HF ratio with statistical significance (P<0.05). The values of ANS activity, ANS balance, Stress resistance, Stress index, have also shown significant changes. For cardiac stability stroke volume power (SP) and Blood Vessel Tension (BVT) were followed, which were both increased after treatment. All changes were statistically significant (P<0.05). Conclusion : The results have shown a positive correlation between the moxibustion treatments and autonomic nervous system responses on cancer patients through the HRV biofeedback testing. This study suggests possible application of moxibustion treatments for managing ANS functions of cancer patients, although additional studies with larger population are necessary to confirm the data.

• Proceedings of the Korean Society for Emotion and Sensibility Conference
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• 2000.11a
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• pp.73-80
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• 2000

The paper is addressed to the topic of physiological response-specificity in disgust induced by visual stimulation. The purpose of this study was to evaluate reproducibility of physiological reactivity pattern during disgust elicited by the International Affective Pictures System (IAPS) in 2 experiments. Twenty-nine subjects participated in the first experiment with 3 visual stimulation sessions with disgust-eliciting slides (3 slides in each 1 min long session). In the second experiment disgust-eliciting slides from the IAPS were presented to 42 subjects in 2 sessions (one slide for 1 min). Spectral power of frontal EEG, skin conductance (SCL, SCR and NS.SCR), heart rate(HR), heart period variability(HPV) and respiration rate were recorded. Visual stimulation evoked 1:.n deceleration, higher power of high frequency component of HPV, increased SCL and NS.SCR frequency, frontal slow alpha blocking and moderate increase in fast beta power in most of the sessions in both experiments. However in the second experiment the EEG pattern associated with disgust showed inconsistent shifts in fast alpha and slow beta bands, but was marked by higher power of theta activity. Our data in both experiments emphasizes presence of disgust-specific profiles of autonomic and at the less extent EEG responses in visual stimulation context. Discussed are potential behavioral mechanisms leading to observed physiological manifestations in disgust elicited by visual stimulation. The results support the consideration that disgust is an withdrawal type negative valence emotion associated with relatively low autonomic arousal (low HR, low amplitude SCRs with relatively high NS.SCR frequency) and moderate EEG activation signs. Obtained data showed more consistent reproducibility of disgust-specific autonomic rather than EEG response patterns during visual stimulation design.