• Title/Summary/Keyword: autoimmunogenic potential

Search Result 3, Processing Time 0.016 seconds

Investigation of autoimmunogenic potential of GX-12, a New anti-HIV DNA Vaccine, by popliteal lymph node assay and autoantibody induction

  • Kang, Kyung-Koo;Park, Min-Seul;Baik, Dae-Hyun;Lee, Dong-Sup;Park, Jae-Hun;Ahn, Byoung-Ok;Kim, Won-Bae
    • Proceedings of the Korean Society of Toxicology Conference
    • /
    • 2002.11b
    • /
    • pp.178-179
    • /
    • 2002
  • GX-12 is a naked DNA vaccine developed by Dong-A Pharmaceutical Company, Green Cross Company and Genexine for the treatment of HIV infection. GX-12 consists of four separate plasmids. This study was performed to investigate the autoimmunogenic potential of GX-12 using primary and secondary PLNA method, and to examine the induction of autoantibodies in mice immunized with GX-12.(omitted)

  • PDF

Assessment of autoimmunogenic potential of autoimmune disease inducing chmecals using the popliteal lymph node assay

  • Kim, Hyung-Soo;Juno H. Eom;Kim, Jin-Ho;Chung, Seung-Tae;Park, Jae-Hyun;Kang, Sun-Kyung;Kim, Dong-Sub
    • Proceedings of the Korean Society of Toxicology Conference
    • /
    • 2001.05a
    • /
    • pp.113-113
    • /
    • 2001
  • The popliteal lymph node assay (PLNA) was proposed to predict autoimmunogenic potential of xenobiotics. This study was conducted to establish the popliteal lymph node assay(PLNA) and to investigate the measurement of lymphocyte subsets can be utilized as an additional parameter in PLNA.(omitted)

  • PDF