• MALSORI
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• no.66
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• pp.41-59
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• 2008

Knowledge in linguistic rhythm of the target language plays a major role in foreign language proficiency. This study attempts to discover valid rhythm features that can be utilized in automatic assessment of non-native English pronunciation. Eight previously proposed and two novel rhythm metrics are investigated with 360 English read speech tokens obtained from 27 Korean learners and 9 native speakers. It is found that some of the speech-rate normalized interval measures and above-word level metrics are effective enough to be further applied for automatic scoring as they are significantly correlated with speakers' proficiency levels. It is also shown that metrics need to be dynamically selected depending upon the structure of target sentences. Results from a preliminary auto-scoring experiment through a Multi Regression analysis suggest that appropriate control of unexpected input utterances is also desirable for better performance.

• Bulletin of the Korean Chemical Society
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• v.29 no.5
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• pp.921-927
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• 2008

Discovery of $\alpha$-glucosidase inhibitors has been actively pursued with the aim to develop therapeutics for the treatment of diabetes and the other carbohydrate mediated diseases. As a method for the discovery of new novel inhibitors of $\alpha$-glucosidase, we have addressed the performance of the computer-aided drug design protocol involving the homology modeling of $\alpha$-glucosidase and the structure-based virtual screening with the two docking tools: FlexX and the automated and improved AutoDock implementing the effects of ligand solvation in the scoring function. The homology modeling of $\alpha$-glucosidase from baker’s yeast provides a high-quality 3-D structure enabling the structure-based inhibitor design. Of the two docking programs under consideration, AutoDock is found to be more accurate than FlexX in terms of scoring putative ligands to the extent of 5-fold enhancement of hit rate in database screening when 1% of database coverage is used as a cutoff. A detailed binding mode analysis of the known inhibitors shows that they can be stabilized in the active site of $\alpha$- glucosidase through the simultaneous establishment of the multiple hydrogen bond and hydrophobic interactions. The present study demonstrates the usefulness of the automated AutoDock program with the improved scoring function as a docking tool for virtual screening of new $\alpha$-glucosidase inhibitors as well as for binding mode analysis to elucidate the activities of known inhibitors.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2013.10a
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• pp.173-176
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• 2013

This paper's questions, and an automatic scoring system written in HTML, and XML-based system that is at issue, the issue questions in a convenient offline automatically how to register, Easy to manage questions of issues, questions and problems of merging the PC and the mobile device in a place that can be obtained without taking the test system study. Server systems, and real-time registration questions merging problem, such as difficulty adjusting to the test required to build the system. Clients communicate with the server using the mobile device and the PC is required to take the exam in the View application, and responses are sent for treatment research.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2014.10a
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• pp.370-372
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• 2014

This study questions, and an automatic scoring system written in HTML, and XML-based system that is at issue, the issue questions in a convenient offline automatically how to register, Easy to manage questions of issues, questions and problems of merging the PC and the mobile device in a place that can be obtained without taking the test system study. Server systems, and real-time registration questions merging problem, such as difficulty adjusting to the test required to build the system. Clients communicate with the server using the mobile device and the PC is required to take the exam in the View application, and responses are sent for treatment research.

• Journal of the Korea Society of Computer and Information
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• v.24 no.11
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• pp.127-133
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• 2019

SQL is the most common language in data processing. Therefore, most of the colleges offer SQL in their curriculum. In this research, an auto scoring SQL test is proposed for the efficient results of SQL education. The system was treated with algorithms instead of using expensive DBMS(Data Base Management System) for automatic scoring, and satisfactory results were produced. For this system, the test question bank was established out of 'personnel management' and 'academic management'. It provides users with different sets of test each time. Scoring was done by dividing tables into two sections. The one that does not change the table(select) and the other that actually changes the table(update, insert, delete). In the case of a search, the answer and response were executed at first and then the results were compared and processed, the user's answers are evaluated by comparing the table with the correct answer. Modification, insertion, and deletion of table actually changes the data table, so data was restored by using ROLLBACK command. This system was implemented and tested 772 times on the 88 students in Computer Information Division of our college. The results of the implementation show that the average scoring time for a test consisting of 10 questions is 0.052 seconds, and the performance of this system is distinguished considering that multiple responses cannot be processed at the same time by a human grader, we want to develop a problem system that takes into account the difficulty of the problem into account near future.

• The Korean Journal of Cytopathology
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• v.9 no.2
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• pp.139-146
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• 1998

The AutoPap 300 QC System is an automated device for the analysis and classification of conventional cervical cytology slides for quality control purpose. These studies evaluated the sensitivity of the AutoPap 300 QC System, and estimated morphologic features other than epithelial abnormality to identify a high quality control(QC) score with the AutoPap 300 QC System. The sensitivity of the AutoPap 300 QC System at 10% review rate for 210 cases of cervicovaginal cytology with low grade squamous intraepithelial lesion(LSIL) and higher grade lesion was assessed, and compared with a 10% random rescreening. The morphologic features, such as presence of endocervical component, dirty background, atrophy, abnormal ceil size, and celluiarity of single atypical cells were estimated in 45 cases of no review and 30 cases of QC review cases. The AutoPap 300 QC System identified 119(56.7%) out of 210 cases with LSIL and higher grade lesion at 10% review rate. It was more sensitive to squamous cell lesions$(50{\sim}62%)$ than to glandular lesions(10%). The dirty background and the scanty cellularity of single atypical cells were significantly related to low QC score. Conclusively, AutoPap 300 QC System is superior to human random rescreen for the identification of false negative smears. The upgrading of this device is required to enhance the defection of glandular lesion and certain Inadequate conditions of the slides.

• Toxicological Research
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• v.18 no.4
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• pp.369-374
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• 2002

The present study was performed to validate an automated image analysis system (Loats Automated Micronucleus Scoring System) for the mouse bone marrow micronucleus assay, comparing with conventional microscopic scoring. Two studies were conducted to provide slides for a comparison of micro-nucleated polychromatic erythrocytes (MNPCEs) values collected manually to those collected by the auto-mated system. Test article A was used as an example of a compound negative for the induction of micronuclei and test article B was wed as a micronucleus-inducing agent to elicit a positive response. Cyclophosphamide was included to provide an positive control in two studies. Bone marrow samples were collected 24 h after administration of test article A and B in male ICR mice. The cells were fixed with absolute methanol and stained with May-Grunwald and Giemsa. The number of MNPCEs was determined by the analysis of 1000 total PCEs per bone marrow sample. In addition to micronucleus scoring, an index of bone marrow toxicity based on PCE ratio (% of PCEs to total erythrocytes) was determined for each sample. The automated and manual scoring was similar when the MNPCEs incidence induced by each test article was less than 10. However manual scoring was able to effectively enumerate micronucleated PCEs in mouse bone marrow when MNPCEs incidence was more than 10, such as cyclophosphamide treatment. Conversely, PCE ratio was superior in computer-assisted image analysis. Taken together, it is suggested that improvement of the automated image analysis may be necessary to render the automatic scoring as sensitive as manual scoring for routine counting of micronuclei, especially because it is superior in objectivity and high throughput scoring.

• Korean Journal of Radiology
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• v.22 no.11
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• pp.1764-1776
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• 2021

Objective: This study aimed to validate a deep learning-based fully automatic calcium scoring (coronary artery calcium [CAC]_auto) system using previously published cardiac computed tomography (CT) cohort data with the manually segmented coronary calcium scoring (CAC_hand) system as the reference standard. Materials and Methods: We developed the CAC_auto system using 100 co-registered, non-enhanced and contrast-enhanced CT scans. For the validation of the CAC_auto system, three previously published CT cohorts (n = 2985) were chosen to represent different clinical scenarios (i.e., 2647 asymptomatic, 220 symptomatic, 118 valve disease) and four CT models. The performance of the CAC_auto system in detecting coronary calcium was determined. The reliability of the system in measuring the Agatston score as compared with CAC_hand was also evaluated per vessel and per patient using intraclass correlation coefficients (ICCs) and Bland-Altman analysis. The agreement between CAC_auto and CAC_hand based on the cardiovascular risk stratification categories (Agatston score: 0, 1-10, 11-100, 101-400, > 400) was evaluated. Results: In 2985 patients, 6218 coronary calcium lesions were identified using CAC_hand. The per-lesion sensitivity and false-positive rate of the CAC_auto system in detecting coronary calcium were 93.3% (5800 of 6218) and 0.11 false-positive lesions per patient, respectively. The CAC_auto system, in measuring the Agatston score, yielded ICCs of 0.99 for all the vessels (left main 0.91, left anterior descending 0.99, left circumflex 0.96, right coronary 0.99). The limits of agreement between CAC_auto and CAC_hand were 1.6 ± 52.2. The linearly weighted kappa value for the Agatston score categorization was 0.94. The main causes of false-positive results were image noise (29.1%, 97/333 lesions), aortic wall calcification (25.5%, 85/333 lesions), and pericardial calcification (24.3%, 81/333 lesions). Conclusion: The atlas-based CAC_auto empowered by deep learning provided accurate calcium score measurement as compared with manual method and risk category classification, which could potentially streamline CAC imaging workflows.

• Tribology and Lubricants
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• v.39 no.5
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• pp.173-182
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• 2023

The composite planetary gear reducer, a power transmission component of armored vehicles, operates at a high torque and is used in severe environments such as mountain, gravel or unpaved roads. Therefore, they must be designed and manufactured to have high durability. To design such a planetary gear reducer, there are numerous specifications to validate, such as selecting the module and the number of teeth of each gear satisfied the requirements, and calculating gear specifications and durability strength. Because planetary gears constitute a combination of several gears, there are many restrictions and interferences in selecting the number of teeth and addendum modification coefficients, and designing the tooth shape. Developing an auto design program is necessary to design various planetary gears more conveniently and quickly. In this study, a planetary gear reducer design software, widely used in various machines and armored vehicles, was developed. This design software can automatically select the number of teeth and modules of the gears, calculate specifications and quickly evaluate its fatigue durability strength and scoring failure according to the planetary gear reducer design theory.

• Journal of the Korean Orthopaedic Association
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• v.55 no.2
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• pp.135-142
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• 2020

Purpose: This paper presents the long term follow-up results of arthroscopic partial repair for massive irreparable rotator cuff tears using a biceps long head auto graft. Materials and Methods: Forty-one patients with massive irreparable rotator cuff tear, who underwent arthroscopic repair, were reviewed retrospectively. Patients who underwent arthroscopic partial repair using a biceps long head auto graft were assigned to group 1, and patients in group 2 underwent arthroscopic partial repair alone. Patients with a less than 50% partial tear of the long head biceps tendon were included in this study. The clinical scores were measured using a visual analogue pain scale (VAS) for pain, range of motion (ROM), The University of California, Los Angeles shoulder score (UCLA), American Shoulder and Elbow Surgeons Shoulder Score (ASES), and Korean Shoulder Scoring System (KSS) scores preoperatively and at the final follow-up. The acromiohumeral interval (AHI) was measured using plain radiographs taken preoperatively and at the final follow-up, and re-tear was evaluated using postoperative ultrasound or magnetic resonance imaging at the last follow-up. Results: The mean age of the patients was 62.1±12.7 years, and the mean follow-up period was 90.3±16.8 months. No significant differences in the VAS and ROM (forward flexion, external rotation, internal rotation) were found between the two groups (p=0.179, p=0.129, p=0.098, p=0.155, respectively). The UCLA (p=0.041), ASES (p=0.023), and KSS (p=0.019) scores showed functional improvements in group 1 compared to group 2. At the last follow-up, the measured AHI values were 9.46±0.41 mm and 6.86±0.64 mm in group 1 and 2, respectively (p=0.032). Re-tear was observed in six out of 21 cases (28.6%) in group 1 and nine out of 20 cases (45.0%) in group 2; the retear rate was significantly lower in group 1 than in group 2 (p=0.011). Conclusion: Arthroscopic partial repair for a massive irreparable rotator cuff tear using a biceps long head auto graft has significant clinical usefulness in functional recovery and decreases the re-tear rates after surgery than arthroscopic partial repair alone, showing favorable results after a long-term follow-up.