• Title/Summary/Keyword: attrition rate

Search Result 52, Processing Time 0.021 seconds

The Characteristic Changes of Electromagnetic Wave Absorption in Fe-based Nanocrystalline P/M Sheet by the Additions of BaTiO3 Powder and Dispersant (BaTiO3 분말과 분산제 첨가에 따른 Fe계 나노결정 P/M시트의 전자파흡수 특성변화)

  • Kim, Mi-Rae;Cho, Hyeon-Jeong;Park, Won-Wook
    • Journal of Powder Materials
    • /
    • v.15 no.1
    • /
    • pp.53-57
    • /
    • 2008
  • The amorphous $Fe_{73}Si_{16}B_7Nb_3Cu_1$(at%) alloy strip was pulverized using a jet mill and an attrition mill to get flake-shaped powder. The flake powder was mixed with dielectric $BaTiO_3$ powder and its dispersant to increase the permittivity. The powders covered with dielectric powders and its dispersant were mixed with a binder and a solvent and then tape-cast to form sheets. The absorbing properties of the sheets were measured to investigate the roles of the dielectric powder and its dispersant. The results showed that the addition of $BaTiO_3$ powders and its dispersant improved the absorbing properties of the sheets noticeably. The powder sheet mixed with 5 wt% of $BaTiO_3$ powder and 1 wt% of dispersant showed the best electromagnetic wave absorption rate because of the increase of the permittivity and the electrical resistance.

An Integrative Approach to Precision Cancer Medicine Using Patient-Derived Xenografts

  • Cho, Sung-Yup;Kang, Wonyoung;Han, Jee Yun;Min, Seoyeon;Kang, Jinjoo;Lee, Ahra;Kwon, Jee Young;Lee, Charles;Park, Hansoo
    • Molecules and Cells
    • /
    • v.39 no.2
    • /
    • pp.77-86
    • /
    • 2016
  • Cancer is a heterogeneous disease caused by diverse genomic alterations in oncogenes and tumor suppressor genes. Despite recent advances in high-throughput sequencing technologies and development of targeted therapies, novel cancer drug development is limited due to the high attrition rate from clinical studies. Patient-derived xenografts (PDX), which are established by the transfer of patient tumors into immunodeficient mice, serve as a platform for co-clinical trials by enabling the integration of clinical data, genomic profiles, and drug responsiveness data to determine precisely targeted therapies. PDX models retain many of the key characteristics of patients' tumors including histology, genomic signature, cellular heterogeneity, and drug responsiveness. These models can also be applied to the development of biomarkers for drug responsiveness and personalized drug selection. This review summarizes our current knowledge of this field, including methodologic aspects, applications in drug development, challenges and limitations, and utilization for precision cancer medicine.

Thermal Decompostion of Methane Using Catalyst in a Fluidized Bed Reactor (유동층반응기에서 촉매를 이용한 메탄 열분해)

  • Jang, Hyun-Tae;Lee, Ji-Yun;Cha, Wang-Seog
    • Journal of the Korea Academia-Industrial cooperation Society
    • /
    • v.9 no.2
    • /
    • pp.487-492
    • /
    • 2008
  • In this paper, Thermocatalytic decomposition of methane in a fluidized bed reactor (FBR) was studied. The technical approach is based on a single-step decomposition of methane over carbon catalyst in air/water vapor free environment. The factors affecting methane decompostion catalyst activity in methane decomposition reactions were examined. The fluidization phenomena in a gas-fluidized bed of catalyst was determined by the analysis of pressure fluctuation properties, and the results were confirmed with characteristics of methane decomposition. The effect of parameters on the H2 yield was examined for methane decompostion. The decompstion rate was affected by the fluidization quality such as mobility, U-Umf, carbon attrition, elutriation and effectiveness density of fluidization gas.

An Efficient Overlay Multicast Scheduling for Composite Stream in P2P Environment (P2P 환경에서 복합 스트림 서비스를 위한 효율적인 오버레이 멀티캐스트 스케줄링)

  • Kim, Jong-Gyung;Choi, Sung-Uk
    • Journal of the Korea Society of Computer and Information
    • /
    • v.13 no.6
    • /
    • pp.233-241
    • /
    • 2008
  • The overlay multicast that has been recently presented as an alternative for the IP multicast needs scheduling method that can apply the system resource and the network bandwidth for the many users. We propose a efficient overlay multicasting network policy for multimedia services with composite stream service topology. And in order to evaluate the ability of the proposed scheme's performance, We test the performance of multi_casting nodes with RTT values, the bandwidth attrition rate for building the network topology and MOR effects with Overcast[5] The result of simulation shows improves about $8{\sim}20%$ of performance.

  • PDF

A Study on the Psychological Responses by the change of Illuminance and Color temperature in LED (LED 광원의 색온도와 조도 변화에 따른 심리반응 연구)

  • Yi, Yon-Soo;Ha, Mi-Kyoung
    • Korean Institute of Interior Design Journal
    • /
    • v.21 no.6
    • /
    • pp.129-136
    • /
    • 2012
  • As the importance of eco-friendly and energy saving issues are emphasized in lighting as consciousness about energy saving is elated worldwide, demand for natural resources such as gas increases, supply of LED lighting is spread. Owing to white LED's development and price fall. It is expected to LED High Luminance Emitting Diode. LED's brightness and long life-time that surpass fluorescent light in the latest as well as is used by back light source of thin film LCD, low electric power attrition rate by advantage do and widen the market at the world lighting lamp market that is potential market. Accordingly, study about suitability of LED lighting is activated but space that apply actual LED lighting fixtures yet is less and advanced researches about LED fixtures' applied apaces are slight compared to existing light source up to now because is not many on this. The result of the experiment shows similar tendency with the existing light sources'. Through a psychological reaction experiment in the LED lighting experiencing space that can control of color temperature and lighting level, this study is wished to use to the data for lighting design of space that LED lighting fixtures are applied hereafter.

  • PDF

Fractures of implant fixtures: a retrospective clinical study

  • Yu, Han-Chang;Kim, Young-Kyun
    • Maxillofacial Plastic and Reconstructive Surgery
    • /
    • v.42
    • /
    • pp.13.1-13.6
    • /
    • 2020
  • Background: The aim of this study was to evaluate the factors that may affect implant fixture fractures. Methods: Patients who experienced implant fixture removal at Seoul National University Bundang Hospital from 2007 to 2015 due to implant fixture fracture were included. Implant/crown ratio, time of implant fracture, clinical symptoms before implant fracture, treatment of fractured implants, and the success and survival rate of the replaced implants were evaluated retrospectively. Results: Thirteen implants were fractured in 12 patients. Patient mean age at the time of fracture was 59.3 years. Of the 13 implants, 7 implants were placed at our hospital, and 6 were placed at a local clinic. The mean crown/implant ratio was 0.83:1. The clinical symptoms before fracture were screw loosening in five implants, marginal bone loss in five implants, and the presence of peri-implant diseases in five implants. All the fractured implants were removed, and 12 out of the 13 sites were re-implanted. Parafunctions were observed in two patients: one with bruxism and one with attrition due to a strong chewing habit. Conclusions: Several clinical symptoms before the fracture of an implant can predict implant fixture failure. Therefore, if these clinical symptoms are observed, appropriate treatments can be taken before more serious complications result.

A Study on the Fabrication of Reinforced Reaction Bonded Alumina Ceramics (반응결합 강화 알루미나세라믹스의 제조에 관한 연구)

  • 김일수;강민수;박정현
    • Journal of the Korean Ceramic Society
    • /
    • v.35 no.4
    • /
    • pp.311-318
    • /
    • 1998
  • The reaction bonded alumina ceramics with reinforced particles which have low shrinkage were pro-duced by blending of SiC or TiC or ZrO2 powders to the mixture of Al metal and Al2O3 powder. The powd-ers were attrition milled isostantically pressed and preheated tio 110$0^{\circ}C$ with a heating rate of $1.5^{\circ}C$/min The specimens were then sintered at the temperature range 1500 to 1$600^{\circ}C$ for 5 hours with a heating rate of 5$^{\circ}C$/min. The specimens showed 5-9% weight gain and 2-9% dimensional expansion through the complete oxidation of Al after preheating up to 11--$^{\circ}C$ the overall dimensional change of the specimens after the reaction sintering at 1500-1$600^{\circ}C$ was 6-12% The maximum densities were 92% theoretical. The fine grain-ed(average grain size :0.4 ${\mu}{\textrm}{m}$) microstructure were observed in the specimen with ZrO2 and SiC. But the microstructure of specimen with TiC was relatively coarse.(average grain size : 2.1 ${\mu}{\textrm}{m}$) The mullite phase was formed by the reaction of Al2O3 and SiO2 in a specimen with SiC. In the TiC contained specimen TiC was oxidized into TiO2 and finally reacted with Al2O3 to form Al2TiO5 during sintering.

  • PDF

Outcomes of Surgical Repair for Truncus Arteriosus: A 30-Year Single-Center Experience

  • Yu Ri Lee;Dong-Hee Kim;Eun Seok Choi;Tae-Jin Yun;Chun Soo Park
    • Journal of Chest Surgery
    • /
    • v.56 no.2
    • /
    • pp.75-86
    • /
    • 2023
  • Background: We investigated the long-term outcomes of truncus arteriosus repair at a single institution with a 30-year study period. Methods: Patients who underwent repair of truncus arteriosus between 1993 and 2022 were reviewed retrospectively. Factors associated with early mortality, overall attrition, and reintervention were identified using appropriate statistical methods. Results: In total, 42 patients were enrolled in this study. The median age and weight at repair were 26 days and 3.5 kg, respectively. Thirty patients (71.4%) underwent 1-stage repair. There were 8 early deaths (19%). In the univariable analysis, undergoing surgery before 2011 was associated with early mortality (p=0.031). The overall survival rate at 10 years was 73.8%. In the multivariable analysis, significant truncal valve (TrV) dysfunction (p=0.010), longer cardiopulmonary bypass time (p=0.018), and the earlier era of surgery (p=0.004) were identified as risk factors for overall mortality. During follow-up, 47 reinterventions were required in 27 patients (64.3%). The freedom from all-cause reintervention rate at 10 years was 23.6%. In the multivariable analysis, associated arch obstruction (p<0.001) and significant TrV dysfunction (p=0.011) were identified as risk factors for all-cause reintervention. Arch obstruction (p=0.027) and a number of TrV cusps other than 3 (p=0.014) were identified as risk factors for right ventricle to pulmonary artery (RV-PA) reintervention, and significant TrV dysfunction was identified as a risk factor for TrV reintervention (p=0.002). Conclusion: Despite recent improvements in survival outcomes after repair of truncus arteriosus, RV-PA or TrV reinterventions were required in a significant number of patients during follow-up.

Modeling of Solid Circulation in a Fluidized-Bed Dry Absorption and Regeneration System for CO2 Removal from Flue Gas (연소기체로부터 CO2 회수를 위한 건식 유동층 흡수-재생 공정의 고체순환 모사)

  • Choi, Jeong-Hoo;Park, Ji-Yong;Yi, Chang-Keun;Jo, Sung-Ho;Son, Jae-Ek;Ryu, Chong Kul;Kim, Sang-Done
    • Korean Chemical Engineering Research
    • /
    • v.43 no.2
    • /
    • pp.286-293
    • /
    • 2005
  • An interpretation on the solid circulation characteristics in a fluidized-bed process has been carried out as a first step to simulate the dry entrained-bed absorption and bubbling-bed regeneration system for $CO_2$ removal from flue gas. A particle population balance has been developed to determine the solid flow rates and particle size distributions in the process. Effects of principal process parameters have been discussed in a laboratory scale process (absorption column: 25 mm i.d., 6 m in height; regeneration column: 0.1 m i.d., 1.2 m in height). The particle size distributions in absorption and regeneration columns were nearly the same. As gas velocity or static bed height in the absorption column increased, soild circulation rate and feed rate of fresh sorbent increased, however, mean particle diameter decreased in the absorption column. As cut diameter of the cyclone of the absorption column increased, solid circulation rate decreased, whereas feed rate of fresh sorbent and mean particle diameter in the absorption column increased. As attrition coefficient of sorbent particle increased, solid circulation rate and feed rate of fresh sorbent increased but mean particle diameter in the absorption column decreased.

Effect of Sintering Temperature on the Thermoelectric Properties of Bismuth Antimony Telluride Prepared by Spark Plasma Sintering (방전플라즈마 소결법으로 제조된 Bismuth Antimony Telluride의 소결온도에 따른 열전특성)

  • Lee, Kyoung-Seok;Seo, Sung-Ho;Jin, Sang-Hyun;Yoo, Bong-Young;Jeong, Young-Keun
    • Korean Journal of Materials Research
    • /
    • v.22 no.6
    • /
    • pp.280-284
    • /
    • 2012
  • Bismuth antimony telluride (BiSbTe) thermoelectric materials were successfully prepared by a spark plasma sintering process. Crystalline BiSbTe ingots were crushed into small pieces and then attrition milled into fine powders of about 300 nm ~ 2${\mu}m$ size under argon gas. Spark plasma sintering was applied on the BiSbTe powders at 240, 320, and $380^{\circ}C$, respectively, under a pressure of 40 MPa in vacuum. The heating rate was $50^{\circ}C$/min and the holding time at the sintering temperature was 10 min. At all sintering temperatures, high density bulk BiSbTe was successfully obtained. The XRD patterns verify that all samples were well matched with the $Bi_{0.5}Sb_{1.5}Te_{3}$. Seebeck coefficient (S), electric conductivity (${\sigma}$) and thermal conductivity (k) were evaluated in a temperature range of $25{\sim}300^{\circ}C$. The thermoelectric properties of BiSbTe were evaluated by the thermoelectric figure of merit, ZT (ZT = $S^2{\sigma}T$/k). The grain size and electric conductivity of sintered BiSbTe increased as the sintering temperature increased but the thermal conductivity was similar at all sintering temperatures. Grain growth reduced the carrier concentration, because grain growth reduced the grain boundaries, which serve as acceptors. Meanwhile, the carrier mobility was greatly increased and the electric conductivity was also improved. Consequentially, the grains grew with increasing sintering temperature and the figure of merit was improved.