• 제목/요약/키워드: attrition rate

검색결과 52건 처리시간 0.025초

BaTiO3 분말과 분산제 첨가에 따른 Fe계 나노결정 P/M시트의 전자파흡수 특성변화 (The Characteristic Changes of Electromagnetic Wave Absorption in Fe-based Nanocrystalline P/M Sheet by the Additions of BaTiO3 Powder and Dispersant)

  • 김미래;조현정;박원욱
    • 한국분말재료학회지
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    • 제15권1호
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    • pp.53-57
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    • 2008
  • The amorphous $Fe_{73}Si_{16}B_7Nb_3Cu_1$(at%) alloy strip was pulverized using a jet mill and an attrition mill to get flake-shaped powder. The flake powder was mixed with dielectric $BaTiO_3$ powder and its dispersant to increase the permittivity. The powders covered with dielectric powders and its dispersant were mixed with a binder and a solvent and then tape-cast to form sheets. The absorbing properties of the sheets were measured to investigate the roles of the dielectric powder and its dispersant. The results showed that the addition of $BaTiO_3$ powders and its dispersant improved the absorbing properties of the sheets noticeably. The powder sheet mixed with 5 wt% of $BaTiO_3$ powder and 1 wt% of dispersant showed the best electromagnetic wave absorption rate because of the increase of the permittivity and the electrical resistance.

An Integrative Approach to Precision Cancer Medicine Using Patient-Derived Xenografts

  • Cho, Sung-Yup;Kang, Wonyoung;Han, Jee Yun;Min, Seoyeon;Kang, Jinjoo;Lee, Ahra;Kwon, Jee Young;Lee, Charles;Park, Hansoo
    • Molecules and Cells
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    • 제39권2호
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    • pp.77-86
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    • 2016
  • Cancer is a heterogeneous disease caused by diverse genomic alterations in oncogenes and tumor suppressor genes. Despite recent advances in high-throughput sequencing technologies and development of targeted therapies, novel cancer drug development is limited due to the high attrition rate from clinical studies. Patient-derived xenografts (PDX), which are established by the transfer of patient tumors into immunodeficient mice, serve as a platform for co-clinical trials by enabling the integration of clinical data, genomic profiles, and drug responsiveness data to determine precisely targeted therapies. PDX models retain many of the key characteristics of patients' tumors including histology, genomic signature, cellular heterogeneity, and drug responsiveness. These models can also be applied to the development of biomarkers for drug responsiveness and personalized drug selection. This review summarizes our current knowledge of this field, including methodologic aspects, applications in drug development, challenges and limitations, and utilization for precision cancer medicine.

유동층반응기에서 촉매를 이용한 메탄 열분해 (Thermal Decompostion of Methane Using Catalyst in a Fluidized Bed Reactor)

  • 장현태;이지윤;차왕석
    • 한국산학기술학회논문지
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    • 제9권2호
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    • pp.487-492
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    • 2008
  • 본 논문은 유동층반응기에서 메탄 열분해에 의한 수소 생산과 탄소 생성에 대한 연구를 수행하였다. 환경에 대한 영향을 최소화한 상태에서 one-step에 의한 메탄의 전환반응을 메탄 분해촉매활성에 영향을 미치는 인자에 대하여 연구하였다. 측정된 압력요동특성치의 해석을 통하여 유동층 열분해촉매의 유동화현상을 측정하였으며, 유동화특성에 따른 메탄열분해능을 측정하였다. 메탄의 분해능는 생성되는 수소의 농도로부터 측정하였다. 유동층의 특성인 층내 입자 이동성, U-Umf, 마모, 비산유출, 유동화가스의 효율밀도에 따른 분해효율에 미치는 영향을 고찰하였다.

P2P 환경에서 복합 스트림 서비스를 위한 효율적인 오버레이 멀티캐스트 스케줄링 (An Efficient Overlay Multicast Scheduling for Composite Stream in P2P Environment)

  • 김종경;최성욱
    • 한국컴퓨터정보학회논문지
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    • 제13권6호
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    • pp.233-241
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    • 2008
  • 최근 IP 멀티캐스팅 대신에 각광을 받고 있는 오버레이 멀티캐스팅은 다수의 사용자를 위하여 서버의 자원과 네트워크의 대역폭을 효율적으로 활용할 수 있는 스케줄링 기법이 필요하다. 따라서 본 논문에서는 효율적인 멀티미디어 서비스를 위하여 오버레이 멀티캐스팅 환경에서의 복합스트림 토폴로지 정책을 제안한다. 본 논문의 성능 평가를 위하여 본 논문과 유사성을 가진 Overcast[5]와 비교하여 멀티캐스트에 참여한 노드들의 RTT(Round Trip Time) 수치, 트리 구축시간에 따른 대역폭 소모량 측정, 그리고 수행시간에 따른 MOR 영향 실험을 하였다. 그 결과 약 $8{\sim}20%$의 성능의 향상을 보여 주었다.

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LED 광원의 색온도와 조도 변화에 따른 심리반응 연구 (A Study on the Psychological Responses by the change of Illuminance and Color temperature in LED)

  • 이연수;하미경
    • 한국실내디자인학회논문집
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    • 제21권6호
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    • pp.129-136
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    • 2012
  • As the importance of eco-friendly and energy saving issues are emphasized in lighting as consciousness about energy saving is elated worldwide, demand for natural resources such as gas increases, supply of LED lighting is spread. Owing to white LED's development and price fall. It is expected to LED High Luminance Emitting Diode. LED's brightness and long life-time that surpass fluorescent light in the latest as well as is used by back light source of thin film LCD, low electric power attrition rate by advantage do and widen the market at the world lighting lamp market that is potential market. Accordingly, study about suitability of LED lighting is activated but space that apply actual LED lighting fixtures yet is less and advanced researches about LED fixtures' applied apaces are slight compared to existing light source up to now because is not many on this. The result of the experiment shows similar tendency with the existing light sources'. Through a psychological reaction experiment in the LED lighting experiencing space that can control of color temperature and lighting level, this study is wished to use to the data for lighting design of space that LED lighting fixtures are applied hereafter.

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Fractures of implant fixtures: a retrospective clinical study

  • Yu, Han-Chang;Kim, Young-Kyun
    • Maxillofacial Plastic and Reconstructive Surgery
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    • 제42권
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    • pp.13.1-13.6
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    • 2020
  • Background: The aim of this study was to evaluate the factors that may affect implant fixture fractures. Methods: Patients who experienced implant fixture removal at Seoul National University Bundang Hospital from 2007 to 2015 due to implant fixture fracture were included. Implant/crown ratio, time of implant fracture, clinical symptoms before implant fracture, treatment of fractured implants, and the success and survival rate of the replaced implants were evaluated retrospectively. Results: Thirteen implants were fractured in 12 patients. Patient mean age at the time of fracture was 59.3 years. Of the 13 implants, 7 implants were placed at our hospital, and 6 were placed at a local clinic. The mean crown/implant ratio was 0.83:1. The clinical symptoms before fracture were screw loosening in five implants, marginal bone loss in five implants, and the presence of peri-implant diseases in five implants. All the fractured implants were removed, and 12 out of the 13 sites were re-implanted. Parafunctions were observed in two patients: one with bruxism and one with attrition due to a strong chewing habit. Conclusions: Several clinical symptoms before the fracture of an implant can predict implant fixture failure. Therefore, if these clinical symptoms are observed, appropriate treatments can be taken before more serious complications result.

반응결합 강화 알루미나세라믹스의 제조에 관한 연구 (A Study on the Fabrication of Reinforced Reaction Bonded Alumina Ceramics)

  • 김일수;강민수;박정현
    • 한국세라믹학회지
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    • 제35권4호
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    • pp.311-318
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    • 1998
  • The reaction bonded alumina ceramics with reinforced particles which have low shrinkage were pro-duced by blending of SiC or TiC or ZrO2 powders to the mixture of Al metal and Al2O3 powder. The powd-ers were attrition milled isostantically pressed and preheated tio 110$0^{\circ}C$ with a heating rate of $1.5^{\circ}C$/min The specimens were then sintered at the temperature range 1500 to 1$600^{\circ}C$ for 5 hours with a heating rate of 5$^{\circ}C$/min. The specimens showed 5-9% weight gain and 2-9% dimensional expansion through the complete oxidation of Al after preheating up to 11--$^{\circ}C$ the overall dimensional change of the specimens after the reaction sintering at 1500-1$600^{\circ}C$ was 6-12% The maximum densities were 92% theoretical. The fine grain-ed(average grain size :0.4 ${\mu}{\textrm}{m}$) microstructure were observed in the specimen with ZrO2 and SiC. But the microstructure of specimen with TiC was relatively coarse.(average grain size : 2.1 ${\mu}{\textrm}{m}$) The mullite phase was formed by the reaction of Al2O3 and SiO2 in a specimen with SiC. In the TiC contained specimen TiC was oxidized into TiO2 and finally reacted with Al2O3 to form Al2TiO5 during sintering.

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Outcomes of Surgical Repair for Truncus Arteriosus: A 30-Year Single-Center Experience

  • Yu Ri Lee;Dong-Hee Kim;Eun Seok Choi;Tae-Jin Yun;Chun Soo Park
    • Journal of Chest Surgery
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    • 제56권2호
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    • pp.75-86
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    • 2023
  • Background: We investigated the long-term outcomes of truncus arteriosus repair at a single institution with a 30-year study period. Methods: Patients who underwent repair of truncus arteriosus between 1993 and 2022 were reviewed retrospectively. Factors associated with early mortality, overall attrition, and reintervention were identified using appropriate statistical methods. Results: In total, 42 patients were enrolled in this study. The median age and weight at repair were 26 days and 3.5 kg, respectively. Thirty patients (71.4%) underwent 1-stage repair. There were 8 early deaths (19%). In the univariable analysis, undergoing surgery before 2011 was associated with early mortality (p=0.031). The overall survival rate at 10 years was 73.8%. In the multivariable analysis, significant truncal valve (TrV) dysfunction (p=0.010), longer cardiopulmonary bypass time (p=0.018), and the earlier era of surgery (p=0.004) were identified as risk factors for overall mortality. During follow-up, 47 reinterventions were required in 27 patients (64.3%). The freedom from all-cause reintervention rate at 10 years was 23.6%. In the multivariable analysis, associated arch obstruction (p<0.001) and significant TrV dysfunction (p=0.011) were identified as risk factors for all-cause reintervention. Arch obstruction (p=0.027) and a number of TrV cusps other than 3 (p=0.014) were identified as risk factors for right ventricle to pulmonary artery (RV-PA) reintervention, and significant TrV dysfunction was identified as a risk factor for TrV reintervention (p=0.002). Conclusion: Despite recent improvements in survival outcomes after repair of truncus arteriosus, RV-PA or TrV reinterventions were required in a significant number of patients during follow-up.

연소기체로부터 CO2 회수를 위한 건식 유동층 흡수-재생 공정의 고체순환 모사 (Modeling of Solid Circulation in a Fluidized-Bed Dry Absorption and Regeneration System for CO2 Removal from Flue Gas)

  • 최정후;박지용;이창근;조성호;손재익;류청걸;김상돈
    • Korean Chemical Engineering Research
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    • 제43권2호
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    • pp.286-293
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    • 2005
  • 기체 수송층 흡수탑과 기포 유동층 재생탑으로 구성된 $CO_2$ 회수 공정에 대한 해석의 첫 단계로 이 공정에서 고체 순환특성을 해석하였다. 흡수제 고체 입자에 대한 입도별 물질수지를 해석하여 공정의 흐름에서 고체 흐름량과 입도 분포를 결정하였다. 실험실 규모 공정(흡수탑: 직경 25 mm, 높이 6 m; 재생탑: 직경 0.1 m, 높이 1.2 m)에서 고체순환특성을 모사하였다. 흡수탑의 입도분포는 재생탑의 입도분포와 거의 같았다. 흡수탑에서 유속과 정체층 높이가 증가함에 따라서 고체순환량과 새 흡수제 주입량은 증가하였다. 반면에 흡수탑 내 입자의 평균입경은 감소하였다. 흡수탑사이클론의 절단입도가 증가함에 따라서 고체순환속도는 감소하였으며, 새 흡수제 주입속도와 흡수탑 내 입자의 평균 입경은 증가하였다. 흡수제 입자의 마모계수가 증가함에 따라서 고체순환속도는 증가하고, 새 흡수제 주입속도는 증가하며, 흡수탑 내 입자의 평균입경은 감소하였다.

방전플라즈마 소결법으로 제조된 Bismuth Antimony Telluride의 소결온도에 따른 열전특성 (Effect of Sintering Temperature on the Thermoelectric Properties of Bismuth Antimony Telluride Prepared by Spark Plasma Sintering)

  • 이경석;서성호;진상현;유봉영;정영근
    • 한국재료학회지
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    • 제22권6호
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    • pp.280-284
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    • 2012
  • Bismuth antimony telluride (BiSbTe) thermoelectric materials were successfully prepared by a spark plasma sintering process. Crystalline BiSbTe ingots were crushed into small pieces and then attrition milled into fine powders of about 300 nm ~ 2${\mu}m$ size under argon gas. Spark plasma sintering was applied on the BiSbTe powders at 240, 320, and $380^{\circ}C$, respectively, under a pressure of 40 MPa in vacuum. The heating rate was $50^{\circ}C$/min and the holding time at the sintering temperature was 10 min. At all sintering temperatures, high density bulk BiSbTe was successfully obtained. The XRD patterns verify that all samples were well matched with the $Bi_{0.5}Sb_{1.5}Te_{3}$. Seebeck coefficient (S), electric conductivity (${\sigma}$) and thermal conductivity (k) were evaluated in a temperature range of $25{\sim}300^{\circ}C$. The thermoelectric properties of BiSbTe were evaluated by the thermoelectric figure of merit, ZT (ZT = $S^2{\sigma}T$/k). The grain size and electric conductivity of sintered BiSbTe increased as the sintering temperature increased but the thermal conductivity was similar at all sintering temperatures. Grain growth reduced the carrier concentration, because grain growth reduced the grain boundaries, which serve as acceptors. Meanwhile, the carrier mobility was greatly increased and the electric conductivity was also improved. Consequentially, the grains grew with increasing sintering temperature and the figure of merit was improved.