• 대한의생명과학회지
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• 제13권2호
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• pp.157-160
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• 2007

Endoplasmic reticulum (ER) plays formation of disulfide bonds and proper folding of secretory proteins. Cellular responses to ER stress enhances the stress-activated kinase pathway and the induces a lot of immediate-early genes. Among of them, the early growth response-1 (Egr-1), a transcription factor, which plays an important role in cell growth, development, differentiation, apoptosis and various types of injury. For that reason, we have tested the expression of Egr-1 against ER stress inducible drugs (tunicamycin, DTT, A23187 and BFA) to understand what kind of aspect occurred by ER stresses.

• 대한약학회:학술대회논문집
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• 대한약학회 2002년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.2
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• pp.276.2-276.2
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• 2002

Glycosaminoglycans(PT -Gag) were isolated from the porcine testis. From the PT -Gag. we obtained two different types of Gag fractions using Dowex macroporous Resin MSA-1 column. PT-Gag-1.5% NaCl and PT -Gag-16% NaCl. Various biological activities of the GAGs were examined in aspect of anticoagulant and immunomodulating activity. The anticoagulant activity of the GAGs was evaluated by activated partial thromboplastin time (aPTT ) assay and thrombin time (TT) assay. The GAGs of porcine testis markedly increased the clotting times of both of aPTT and TT. showing that PT-Gag-16% NaCl was more effective than PT-Gag-1.5% NaCl. The immunomodulating activity of the GAGs was examined in relation to regulation of cytokine production of mutine peritoneal macrophages. Treatment with the GAGs promonently enhanced the prodution of cytokines. IFN-${\gamma}$, from macrophages. Taken together. GAGs isolated from porcine testis possess biological functions such as anticoagulant and immunomodulating activity.

• Journal of Plant Biotechnology
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• 제38권4호
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• pp.278-284
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• 2011

The CCR4-CAF1-NOT complex-mediated degradation of mRNA is a fundamental aspect of gene regulation in eukaryotes. We herein examined the role of AtCAF1 in the innate immune and wound responses of plants. Our results showed that overexpression of AtCAF1 significantly downregulated the transcript level of EFR but not FLS2 and BRI1, as well as abolished up-regulated expression pattern of EFR in response to wounding. Consistently, Agrobacteriummediated transient expression of GUS was highly enhanced in the transgenic plants overexpressing AtCAF. Furthermore, JA responsive genes were down-regulated by overexpression of AtCAF, causing the transgenic plants overexpressing AtCAF more susceptible to necrotrophic fungal pathogen, Botrytis cinerea. These results suggest that The CCR4-CAF1-NOT complex-mediated degradation of mRNA negatively regulates wounding-mediated disease resistance in Arabidopsis thaliana.

• 대한안전경영과학회지
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• 제16권3호
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• pp.185-194
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• 2014

Internal engine is the main power source of vehicle and is the main source of air pollution. To satisfy this getting rigorous emission regulation, it must be solved simultaneously the dilemma of reducing emission gas and increasing heat efficiency. Diesel engine is preferred compare with gasoline engine in aspect of energy consumption but it must be solved reducing the containing of NOx, CO and HC. In this study: 1. Looking for alternative of performance improvement of Exhaust Gas Recirculation(EGR) which is emission gas reduction system. 2. Reducing malfunction of controlling emission gas. 3. Made possible precision control.

• 대한약학회:학술대회논문집
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• 대한약학회 2002년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.2
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• pp.327.1-327.1
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• 2002

Glycosaminoglycans(PT -Gag) were isolated from the porcine testis. From the PT -Gag, we obtained two different types of Gag fractions using Dowex macro porous Resin MSA-1 column, PT -Gag-1.5% NaCl and PT -Gag-16% NaCl. Various biological activities of the GAGs were examined in aspect of anticoagulant and immunomodulating activity. The anticoagulant activity of the GAGs was evaluated by activated partial thromboplastin time (aPTT ) assay and thrombin time (TT) assay. The GAGs of porcine testis markedly incresed the clotting times of both of aPTT and TT. showing that PT-Gag-16% NaCl was more effective than PT-Gag-1.5% NaCl. The immunomodulating activityof the GAGs was examined in relation to regulation of xytoxine prodution of murine peritoeal maerophages. Taken together. GAGs isolated from porcine testis possess bilolgical functions such as anticoagulant and immunomodulating activity.

• 대한안전경영과학회:학술대회논문집
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• 대한안전경영과학회 2012년 추계학술대회
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• pp.245-252
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• 2012

Internal engine is the main power source of vehicle and is the main source of air pollution. To satisfy this getting rigorous emission regulation, it must be solved simultaneously the dilemma of reducing emission gas and increasing heat efficiency. Diesel engine is preferred compare with gasoline engine in aspect of energy consumption but it must be solved reducing the containing of NOx, CO and HC. In this study 1. Looking for alternative of performance improvement of Exhaust Gas Recirculation(EGR) which is emission gas reduction system, 2. Reducing malfunction of controlling emission gas 3. Made possible precision control.

• Molecules and Cells
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• 제20권2호
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• pp.173-182
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• 2005

Heat shock protein gp96 is an endoplasmic reticulum chaperone, belonging to the HSP90 family. The function of gp96 as a molecular chaperone was discovered more than 10 years ago, but its importance has been overshadowed by the brilliance of its role in immune responses. It is now clear that gp96 is instrumental in the initiation of both the innate and adaptive immunity. Recently, the roles of gp96 in protein homeostasis, as well as in cell differentiation and development, are beginning to draw more attention due to rapid development in the structural study of HSP90 and some surprising new discoveries from genetic studies of gp96. In this review, we focus on the aspect of gp96 as an ER molecular chaperone in protein maturation, peptide binding and the regulation of its activity.

• Journal of Information Technology Applications and Management
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• 제14권3호
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• pp.199-225
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• 2007

This study deals with the regulatory policy of government on the convergence of broadcasting and telecommunication by applying rent seeking theory to Internet Protocal TV (IPTV). Existing literature has mainly focused on the negative implications of rent seeking since Tullock [1967], Krueger [1974] and Buchanan [1980]. We have investigated the regulatory policy along with the progress of the convergence of broadcasting and telecommunication. Regulatory policy on broadcasting, despite its impartial intent. has created the entry barrier in the industry, resulting in high rents. Meanwhile, regulatory policy in telecommunication is more geared by the encouragement of more competitive environments, resulting in reasonably low rents in the market. Regulatory policy in the age of convergence needs to improve the efficacy of the industry and welfare, while maintaining the rent at a reasonably low level. This research has contributed to emphasizing the positive aspect of rent seeking in policy concerned with the convergence of broadcasting and telecommunication, notably IPTV.

• 한국진공학회:학술대회논문집
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• 한국진공학회 2011년도 제41회 하계 정기 학술대회 초록집
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• pp.61-61
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• 2011

Polymer solar cells have become one of the rising next generation solar cells due to their potential for lightweight and bendable plastic solar modules. Recently, the power conversion efficiency of polymer solar cells has reached ~8 %, which can make ~6 % plastic solar modules when it comes to the modular aperture ratio of ~80 %. Although this efficiency is far behind that of conventional inorganic solar cells, the plastic solar modules are expected to create new energy market into which the inorganic solar modules could not make inroads. In the near future, the plastic solar modules can be integrated with consumer electronics that should overcome the regulation of energy consumption. For this application, the polymer solar cells should be fabricated in a variety of module shapes, which can be resolved by employing conventional and/or advanced coating and molding technologies of plastics products. In this tutorial, the fundamental aspect of polymer solar cells will be briefly introduced and then recent trends in terms of materials and devices will be reviewed together with showing recent results in organic nanoelectronics laboratory.

• 대한전기학회:학술대회논문집
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• 대한전기학회 2006년도 제37회 하계학술대회 논문집 A
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• pp.286-287
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• 2006

In this paper, an experiment result on overload of distribution transformer was arranged by top oil temperature depending on capacity and time. This result shows the definition on overload of transformer is different by some factors such as ambient temperature and immediate load. In other words, increased temperature in range of regulation(50K) has time to spare even if the condition of transformer is overload. The algorithm presented in this paper is based on the international standard (IEEE std C57.91), and the safety of switchboard is diagnosed by this aspect mentioned on overload of transformer.