• Journal of Animal Science and Technology
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• v.51 no.6
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• pp.471-484
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• 2009

The peri-implantation period in mammals is critical with respect to survival of the conceptus (embryo/fetus and associated extraembryonic membranes) and establishment of pregnancy. During this period of pregnancy, reciprocal communication between ovary, conceptus, and endometrium is required for successful implantation and placentation. At this time, interferon tau (IFNT) is synthesized and secreted by the mononuclear trophectodermal cells of the conceptus between days 10 and 21~25. The actions of IFNT to signal pregnancy recognition and induce or increase expression of IFNT-stimulated genes (ISGs), such as ISG15 and OAS, are mediated by the Type I IFN signal transduction pathway. This article reviews the history, signaling pathways of IFNT and the uterine expression of several IFNT-stimulated genes during the peri-implantation period. Collectively, these newly identified genes are believed to be critical to unraveling the mechanism(s) of reciprocal fetal-maternal interactions required for successful implantation and pregnancy.

• Proceedings of the Korean Society for Food Science of Animal Resources Conference
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• 2002.05a
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• pp.17-25
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• 2002

Application of electrical stimulation in the red meat species (eg. beef and sheep) processing has been erratic around the world and this may reflect an incomplete knowledge of how to optimise the technology. Although it is well established that stimulation increases the rate of post-mortem glycolysis other biochemical and biophysical effects have been implicated with the use of this technology. On the basis of currently available knowledge, this mini-review seeks to examine the current theories about the effect of stimulation on post-mortem muscle. The classical view that stimulation prevents muscle from shortening excessively during rigor development has been expanded to include the possibility that it also results in physical disruption of muscle structure. The interaction of these effects with the acceleration of the rate of proteolysis through activation of the calpain protease system has not been comprehensively reviewed in the past. As a result of conclusion driven, this article highlights several areas that may prove fruitful for further research. The challenge for further development of electrical stimulation systems is optimisation of the activation of the enzyme systems in parallel with manipulation of chilling regimes so as to ensure rigor mortis is achieved at temperatures which minimise shortening. The potential of regional stimulation of sections of the carcass to achieve this outcome is worthy of study given the different fibre composition of muscles and temperature gradients.

• Journal of Periodontal and Implant Science
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• v.40 no.4
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• pp.153-163
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• 2010

Periodontal disease, as a polymicrobial disease, is globally endemic as well as being a global epidemic. It is the leading cause for tooth loss in the adult population and has been positively related to life-threatening systemic diseases such as atherosclerosis and diabetes. As a result, it is clear that more sophisticated therapeutic modalities need to be developed, which may include vaccines. Up to now, however, no periodontal vaccine trial has been successful in satisfying all the requirements; to prevent the colonization of a multiple pathogenic biofilm in the subgingival area, to elicit a high level of effector molecules such as immunoglobulin sufficient to opsonize and phagocytose the invading organisms, to suppress the induced alveolar bone loss, or to stimulate helper T-cell polarization that exerts cytokine functions optimal for protection against bacteria and tissue destruction. This article reviews all the vaccine trials so as to construct a more sophisticated strategy which may be relevant in the future. As an innovative strategy to circumvent these barriers, vaccine trials to stimulate antigen-specific T-cells polarized toward helper T-cells with a regulatory phenotype (Tregs, $CD_{4+}$, $CD_{25+}$, $FoxP_{3+}$) have also been introduced. Targeting not only a single pathogen, but polymicrobial organisms, and targeting not only periodontal disease, but also periodontal disease-triggered systemic disease could be a feasible goal.

• Journal of Oral Medicine and Pain
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• v.43 no.1
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• pp.21-25
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• 2018

Syphilis, one of the most common sexually transmitted diseases, is caused by the microorganism Treponema pallidum. Syphilis consists of several clinical stages that may include signs in the oral and perioral regions. Syphilis is treated effectively with systemic antimicrobial therapy using antibiotics such as penicillin. This article describes a case where topical antibacterial therapy with doxycycline was effective in treating oral papular lesions associated with primary syphilis in a 24-year-old male. He was immediately referred to a dermatologist, and antibiotic therapy was administered in response to positive diagnostic test results for syphilis. Although oral syphilitic lesions may be resolved by dental professionals using topical treatments, syphilitic infections should be managed in consultation with medical specialists using systemic antibiotic therapy.

• English Language & Literature Teaching
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• v.13 no.2
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• pp.25-45
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• 2007

In this article, I discuss an International Collaborative Writing Course on the Internet (ICWCI) that focused on the learning effectiveness Korean EFL students (KEFLSs) perceived to be necessary to exchange with international EFL students (IEFLSs). The course development was based on an internet-based instructional module, applying widely accepted EFL theories for modern foreign language instruction: collaborative learning, process writing, project-based learning, and integrated approaches. Data from online discussion forum, mid-of-semester and end-of-semester surveys, and final oral interviews are conducted and discussed. KEFLSs and IEFLSs were questioned about (a) changes in attitude towards computers assisted language learning (CALL); (b) effect of computer background on motivation; (c) perception of their acquired writing skills; and (d) attitude towards collaborative learning. The result of this study demonstrated that the majority of ICWCI participants said they enjoyed the course, gained fruitful confidence in English communication and computer skills, and felt that they made significant progress in writing skills. In spite of positive benefits created by the ICWCI, it was found that there were some issues that are crucial to run appropriate networked collaborative courses. This study demonstrates that participants' computer skills, basic language proficiency, and local time differences are important factors to be considered when incorporating the ICWCI as these may affect the quality of online instructional courses and students' motivation toward network based collaboration interaction.

• Preventive Nutrition and Food Science
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• v.20 no.3
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• pp.190-197
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• 2015

The aim of this study was to investigate the acute and subacute oral toxicity of crude antifungal compounds produced by Lactobacillus plantarum HD1 in Sprague-Dawley rats. In the acute toxicity study, the crude antifungal compounds (0.625, 1.25, 2.5, and 5.0 g/kg) did not produce mortality, significant changes in general behavior, or changes in the gross appearance of the organs. In the subacute toxicity study, the crude antifungal compounds were administered orally to rats at doses of 0, 0.5, 1.0, and 2.0 g/kg daily for 28 days. There were no test article-related deaths, abnormal clinical signs, or body weight changes. The study also showed no significant differences between the control and treated groups in hematological and serum biochemical parameters, histopathological examination, or any other findings. These results suggest that acute or subacute oral administration of crude antifungal compounds from L. plantarum HD1 is not toxic in rats.

• Steel and Composite Structures
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• v.20 no.1
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• pp.107-125
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• 2016

Steel shear wall system has been used in recent years in tall buildings due to its appropriate behavior advantages such as stiffness, high strength, economic feasibility and high energy absorption capability. Coupled steel plate shear walls consist of two steel shear walls that are connected to each other by steel link beam at each floor level. In this article the frames of 3, 10, and 15 of (C-SPSW) floor with rigid connection were considered in three different lengths of 1.25, 2.5 and 3.75 meters and link beams with plastic section modulus of 100% to the panel beam at each floor level and analyzed using three pairs of accelerograms based on nonlinear dynamic analysis through ABAQUS software and then the performance of walls and link beams at base shear, drift, the period of structure, degree of coupling (DC) and dissipated energy evaluated. The results show that the (C-SPSW) system base shear increases with a decrease in the link beam length, and the drift, main period and dissipated energy of structure decreases. Also the link beam length has different effects on parameters of coupling degrees.

• Transactions of the Korean Society of Mechanical Engineers B
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• v.32 no.3
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• pp.224-230
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• 2008

In this article, $TiO_2$ nanoparticles were synthesized by using $O_2$-enriched coflow, hydrogen, diffusion flames. We investigated the thermal stability of the flame-synthesized $TiO_2$ nanoparticles by examining the crystalline structures of the nanoparticles. Also, the results were compared with those of commercial P-25 nanoparticles. $TiO_2$ nanoparticles, which were spherical with diameters approximately ranging from 30 to 60nm, were synthesized. From the XRD analyses, about 96wt% of the synthesized nanoparticles were anatase-phase. After the heat-treatment at $800^{\circ}C$ for 30 minutes, the synthesized $TiO_2$ nanoparticles showed no significant changes of their shapes and crystalline phases. On the other hand, most of the commercial particles sintered with each other and changed to the rutile-phase. Based on the result of XRD analysis it is believed that the flame-synthesized $TiO_2$ nanoparticles have higher thermal stability at $800^{\circ}C$ than the commercial particles.

• Journal of the Korean Solar Energy Society
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• v.25 no.4
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• pp.21-27
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• 2005

This paper summarizes the results of these efforts by offering a photovoltaic system structure in 50kW middle scale applications installed in Cho-sun University dormitory roof. The combination of photovoltaic system components are interconnected and system monitoring system will be summarized for the purpose of the increasing safety in this article. This paper describes configuration of utility interactive photovoltaic system which generated electric power supplies to dormitory. In order to installing the middle or large scale photovoltaic system, It must investigated the optimal design of system, compute quantity of power generation, economic rate of return and so on. In this paper represent 50kW utility photovoltaic system examination and developed simulation results. The performance of photovoltaic system has been evaluated and analyzed with simulation. The results obtained in this research will be much useful to prior investigation for installing utility interactive photovoltaic system.

• The Journal of Korean Academy of Orthopedic Manual Physical Therapy
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• v.11 no.2
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• pp.19-25
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• 2005

Purpose : Facial palsy goes together not only physical difficulties but also social life's of relationship to other people. Therefore we was devised correction splint and rehabilitation set for facial palsy proofreading. Method : This article was used by questionnaire survey that intended for 140 patients who had got facial palsied such as universities hospitals and oriental hospitals over the country in Korea. The subject matter that faced consciousness of a patient as opposed the awkward rehabilitating tool that a general matter and patient. In the object that the rehabilitation tool which now patient used through a wraps a face in only as a treatment object. Results : 1. The most chief complaints among the facial palsy patients were eating activity (41%), relationship to other people (29%), communication (20% )(Fig. 3). 2. The most needs of the facial palsy patients was aids for early treat (53%), prevented face deformity (16%) etc, (Fig. 4). 3. So we are going to make a correction splint and rehabilitation set for facial palsy, that makes common use broadly in based of medical utility (CAD. 1~7). Conclusion : We invented a correction splint and rehabilitation set for facial palsied patients in based of questionnaire survey.