• Geomechanics and Engineering
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• v.36 no.1
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• pp.71-81
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• 2024

This study analyzes the pull-out behavior of tunnel-type anchorage under various joint conditions, including joint direction, spacing, and position, using a finite element analysis. The validity of the numerical model was evaluated by comparing the results with a small-scaled model test, and the results of the numerical analysis and the small-scaled model test agree very well. The parametric study evaluated the quantitative effects of each influencing factor, such as joint direction, spacing, and position, on the behavior of tunnel-type anchorage using pull-out resistance-displacement curves. The study found that joint direction had a significant effect on the behavior of tunnel-type anchorage, and the pull-out resistance decreased as the displacement level increased from 0.002L to 0.006L (L: anchorage length). It was confirmed that the reduction in pull-out resistance increased as the number of joints in contact with the anchorage body increased and the spacing between the joints decreased. The pull-out behavior of tunnel-type anchorage was thus shown to be significantly influenced by the position and spacing of the rock joints. In addition, it is found that the number of joints through which the anchorage passes, the wider the area where the plastic point occurs, which leads to a decrease in the resistance of the anchorage.

• Earthquakes and Structures
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• v.20 no.2
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• pp.175-185
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• 2021

This study strives to highlight the importance of considering the vertical ground motions (VGM) in the seismic evaluation of RC buildings. To this aim, IDA (Incremental Dynamic Analysis) is conducted on three code-based designed high-rise RC frame-core wall buildings using a suite of earthquake records comprising of significant VGMs. To unravel the significance of the VGM inclusion on the performance of the buildings, IDAs are conducted in two states (with and without the vertical component), and subsequently based on each analysis, fragility curves are developed. Non-simulated collapse criteria are used to determine the collapse state drift ratio and the area under the velocity spectrum (SIm) is taken into account as the intensity measure. The outcome of this study delineates that the inclusion of VGM leads to the increase in the collapse vulnerability of the structures as well as to the change in the pattern of inter-story drifts and failure mode of the buildings. The results suggested that it would be more conservative if the VGM is included in the seismic assessment and the fragility analysis of RC buildings.

• Proceedings of the Korean Society For Composite Materials Conference
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• 2003.04a
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• pp.129-134
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• 2003

The importance of understanding the response of structural composites to impact and CAI cannot be overstated to develop analytical models for impact damage and CAI strength predictions. This paper presents experimental findings observed from quasi-static lateral load tests, low velocity impact tests, CAI strength and open hole compressive strength tests using 3mm thick composite plates ($[45/-45/0/90]_{3s}$ - IM7/8552). The conclusion is drawn that damage areas for both quasi-static lateral load and impact tests are similar and the curves of several drop weight impacts with varying energy levels (between 5.4 J and 18.7 J) fallow the static curve well. In addition, at a given energy the peak force is in good agreement between the static and impact cases. From the CAI strength and open hole compressive strength tests, it is identified that the failure behaviour of the specimens was very similar to that observed in laminated plates with open holes under compression loading. The residual strengths are in good agreement with the measured open hole compressive strengths, considering the impact damage site as an equivalent hole. The experimental findings suggest that simple analytical models for the prediction of impact damage area and CAI strength can be developed on the basis of the failure mechanism observed from the experimental tests.

• Earthquakes and Structures
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• v.23 no.1
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• pp.13-21
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• 2022

Masonry constructions exhibit uncertain behaviors under dynamic effects such as seismic action. Complex issues arise in the idealization of structural systems of buildings having different material types and mechanical properties. In this study, the structural behavior of a vaulted masonry building constructed using full clay brick and lime-based mortar and sitting on consecutive arches was investigated by experimental and numerical approaches. The dimensions of the structure built in the laboratory were 391 × 196 cm, and its height was 234 cm. An incremental repetitive loading was applied to the prototype construction model. Along the gradually increasing loading pattern, the load-displacement curves of the masonry structure were obtained with the assistance of eight linear displacement transducers. In addition, crack formation areas, and relevant causes of its formation were determined. The experimental model was idealized using the finite element method, and numerical analyses were performed for the area considered as linear being under similar loading effect. From the linear analyses, the displacement values and stress distribution of the numerical model were obtained. In addition, the effects of tie members, frequently being used in the supports of curved load-bearing elements, on the structural behavior were examined. Consequently, the experimental and numerical analysis results were comparatively evaluated.

• The Plant Pathology Journal
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• v.23 no.2
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• pp.109-112
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• 2007

This study was to examine the efficacy of a root-dipping application of antagonistic bacterial strains for the control of Phytophthora blight of pepper caused by P. capcisi, and to evaluate their plant growth-promoting effects in the field in 2005 and 2006. The candidate antagonistic rhizobacterial strains CCR04, CCR80, GSE09, ISE13, and ISE14 were treated by dipping plant roots with bacterial suspensions prior to transplanting. The candidate rhizobacterial strains CCR04, CCR80, GSE09, and ISE14 significantly (P=0.05) reduced the disease incidence and the area under the disease progress curves when compared to buffer-treated controls in at least a year test. The metalaxy l(fungicide-treated control) resulted in one of the lowest disease incidences among the treatments in both years. Moreover, the strains CCR04, CCR80, GSE09, and ISE13 significantly (P=0.05) increased the fruit weights and/or numbers of peppers in at least a year test compared to the buffer-treated controls. These results suggest that the antagonistic rhizobacterial strains CCR04, CCR80, and GSE09 could be efficient biocontrol agents by controlling Phytophthora blight of pepper and promoting the plant growth when treated with root-dipping at transplanting.

• Journal of Biomedical Engineering Research
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• v.31 no.3
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• pp.177-186
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• 2010

In 3D ultrasound color Doppler imaging (CDI), 8-16 pulse transmissions (ensembles) per each scanline are used for effective clutter rejection and flow estimation, but it yields a low volume acquisition rate. In this paper, we have evaluated three flow estimation methods: autoregression (AR), eigendecomposition (ED), and autocorrelation combined with adaptive clutter rejection (AC-ACR) for a small ensemble size (E=4). The performance of AR, ED and AC-ACR methods was compared using 2D and 3D in vivo data acquired under different clutter conditions (common carotid artery, kidney and liver). To evaluate the effectiveness of three methods, receiver operating characteristic (ROC) curves were generated. For 2D kidney in vivo data, the AC-ACR method outperforms the AR and ED methods in terms of the area under the ROC curve (AUC) (0.852 vs. 0.793 and 0.813, respectively). Similarly, the AC-ACR method shows higher AUC values for 2D liver in vivo data compared to the AR and ED methods (0.855 vs. 0.807 and 0.823, respectively). For the common carotid artery data, the AR provides higher AUC values, but it suffers from biased estimates. For 3D in vivo data acquired from a kidney transplant patient, the AC-ACR with E=4 provides an AUC value of 0.799. These in vivo experiment results indicate that the AC-ACR method can provide more robust flow estimates compared to the AR and ED methods with a small ensemble size.

• Imaging Science in Dentistry
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• v.34 no.1
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• pp.1-5
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• 2004

Purpose: To evaluate the diagnostic accuracy of occlusal and proximal caries detection using CCD, CMOS, PSP and film system. Materials and Methods : 32 occlusal and 30 proximal tooth surfaces were radiographed under standardized conditions using 3 digital systems; CCD (CDX-2000HQ, Biomedysis Co., Seoul, Korea), CMOS (Schick, Schick Inc., Long Island, USA), PSP (Digora/sup (R)/FMX, Orion Co./Soredex, Helsinki, Finland) and I film system (Kodak Insight, Eastman Kodak, Rochester, USA). 5 observers examined the radiographs for occlusal and proximal caries using a 5-point confidence scale. The presence of caries was validated histologically and radiographically. Diagnostic accuracy was evaluated using ROC curve areas (Az). Results: Analysis using ROC curves revealed the area under each curve which indicated a diagnostic accuracy. For occlusal caries, Kodak Insight film had an Az of 0.765, CCD one of 0.730, CMOS one of 0.742 and PSP one of 0.735. For proximal caries, Kodak Insight film had an Az of 0.833, CCD one of 0.832, CMOS one of 0.828 and PSP one of 0.868. No statistically significant difference was noted between any of the imaging modalities. Conclusion: CCD, CMOS, PSP and film performed equally well in the detection of occlusal and proximal dental caries. CCD, CMOS and PSP-based digital images provided a level of diagnostic performance comparable to Kodak Insight film.

• Asian Pacific Journal of Cancer Prevention
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• v.14 no.9
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• pp.5043-5047
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• 2013

Background: This is a part of a larger effort to characterize the effects on socio-economic factors (SEFs) on cancer outcome. Surveillance, Epidemiology and End Result (SEER) bone and joint sarcoma (BJS) data were used to identify potential disparities in cause specific survival (CSS). Materials and Methods: This study analyzed SEFs in conjunction with biologic and treatment factors. Absolute BJS specific risks were calculated and the areas under the receiver operating characteristic (ROC) curve were computed for predictors. Actuarial survival analysis was performed with Kaplan-Meier method. Kolmogorov-Smirnov's 2-sample test was used to for comparing two survival curves. Cox proportional hazard model was used for multivariate analysis. Results: There were 13501 patients diagnosed BJS from 1973 to 2009. The mean follow up time (SD) was 75.6 (90.1) months. Staging was the highest predictive factor of outcome (ROC area of 0.68). SEER stage, histology, primary site and sex were highly significant pre-treatment predictors of CSS. Under multivariate analysis, patients living in low income neighborhoods and rural areas had a 2% and 5% disadvantage in cause specific survival respectively. Conclusions: This study has found 2-5% decrement of CSS of BJS due to SEFs. These data may be used to generate testable hypothesis for future clinical trials to eliminate BJS outcome disparities.

• Journal of Veterinary Science
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• v.22 no.6
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• pp.41.1-41.14
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• 2021

Background: Our previously prepared ceftiofur (CEF) hydrochloride oily suspension shows potential wide applications for controlling swine Streptococcus suis infections, while the irrational dose has not been formulated. Objectives: The rational dose regimens of CEF oily suspension against S. suis were systematically studied using a pharmacokinetic-pharmacodynamic model method. Methods: The healthy and infected pigs were intramuscularly administered CEF hydrochloride oily suspension at a single dose of 5 mg/kg, and then the plasma and pulmonary epithelial lining fluid (PELF) were collected at different times. The minimum inhibitory concentration (MIC), minimal bactericidal concentration, mutant prevention concentration (MPC), post-antibiotic effect (PAE), and time-killing curves were determined. Subsequently, the area under the curve by the MIC (AUC_0-24h/MIC) values of desfuroylceftiofur (DFC) in the PELF was obtained by integrating in vivo pharmacokinetic data of the infected pigs and ex vivo pharmacodynamic data using the sigmoid E_max (Hill) equation. The dose was calculated based on the AUC_0-24h/MIC values for bacteriostatic action, bactericidal action, and bacterial elimination. Results: The peak concentration, the area under the concentration-time curve, and the time to peak for PELF's DFC were 24.76 ± 0.92 ㎍/mL, 811.99 ± 54.70 ㎍·h/mL, and 8.00 h in healthy pigs, and 33.04 ± 0.99 ㎍/mL, 735.85 ± 26.20 ㎍·h/mL, and 8.00 h in infected pigs, respectively. The MIC of PELF's DFC against S. suis strain was 0.25 ㎍/mL. There was strong concentration-dependent activity as determined by MPC, PAE, and the time-killing curves. The AUC_0-24h/MIC values of PELF's DFC for bacteriostatic activity, bactericidal activity, and virtual eradication of bacteria were 6.54 h, 9.69 h, and 11.49 h, respectively. Thus, a dosage regimen of 1.94 mg/kg every 72 h could be sufficient to reach bactericidal activity. Conclusions: A rational dosage regimen was recommended, and it could assist in increasing the treatment effectiveness of CEF hydrochloride oily suspension against S. Suis infections.

• Asian Pacific Journal of Cancer Prevention
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• v.16 no.9
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• pp.3867-3870
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• 2015

Background: To explore whether combined detection of serum tumor markers (CEA, CA72-4, CA19-9 and TSGF) improve the sensitivity and accuracy in the diagnosis of gastric cancer (GC). Materials and Methods: An automatic chemiluminescence immune analyzer with matched kits were used to determine the levels of serum CEA, CA72-4, CA19-9 and TSGF in 45 patients with gastric cancer (GC group), 40 patients with gastric benign diseases (GBD group) hospitalized in the same period and 30 healthy people undergoing a physical examination. The values of those 4 tumor markers in the diagnosis of gastric cancer was analyzed. Results: The levels of serum CEA, CA72-4, CA19-9 and TSGF of the GC group were higher than those of the GBD group and healthy examined people and the differences were significant (P<0.001). The area under receiver operating characteristic (ROC) curves for single detection of CEA, CA72-4, CA19-9 and TSGF in the diagnosis of GC was 0.833, 0.805, 0.810 and 0.839, respectively. The optimal cutoff values for these 4 indices were 2.36 ng/mL, 3.06 U/mL, 5.72 U/mL and 60.7 U/mL, respectively. With combined detection of tumor markers, the diagnostic power of those 4 indices was best, with an area under the ROC curve of 0.913 (95%CI 0.866~0.985), a sensitivity of 88.9% and a diagnostic accuracy of 90.4%. Conclusions: Combined detection of serum CEA, CA72-4, CA19-9 and TSGF increases the sensitivity and accuracy in diagnosis of GC, so it can be regarded as the important means for early diagnosis.