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The Anti-obesity Effects of Bangpungtongseong-san and Daesiho-tang: A Study Protocol of Randomized, Double-blinded Clinical Trial (방풍통성산 및 대시호탕의 항비만효과 분석: 단일기관 무작위배정 이중맹검 임상시험 프로토콜)

  • Oh, Jihong;Shim, Hyeyoon;Cha, Jiyun;Kim, Ho Seok;Kim, Min Ji;Ahn, Eun Kyung;Lee, Myeong-Jong;Lee, Jun-Hwan;Kim, Hojun
    • Journal of Korean Medicine for Obesity Research
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    • v.20 no.2
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    • pp.138-148
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    • 2020
  • Objectives: The aim of this study is to evaluate the effects of Bangpungtongseong-san (Fangfengtongsheng-san, BTS) and Daesiho-tang (Dachaihu-tang, DST) on weight loss and improvement in lipid metabolism and glucose metabolism. Furthermore, we intend to develop a prediction model for drug effects through the analysis of the single nucleotide polymorphism (SNP), gut-microbiota, and the expression of immune-related biomarkers. Methods: This study is a single-center, randomized, double-blind, parallel-design clinical trial. One hundred twenty-eight participants will be assigned to the BTS group (n=64) and DST group (n=64). Both groups will be administered 4 g medication three times a day for up to 2 weeks. The primary outcomes is weight loss. The secondary outcomes include bioelectrical impedance analysis, waist circumstance, body mass index, total cholesterol, high-density lipoprotein, triglyceride, insulin resistance. The exploratory outcomes include 3-day dietary recall, food frequency questionnaire, quality of life questionnaire, gut microbiota analysis, immune biomarkers analysis, and SNP analysis. Assessment will be made at baseline and at week 4, 8, and 12. Conclusions: This protocol will be implemented by approval of the Institutional Review Board of Dongguk University. The results of this trial will provide a systematic evidence for the treatment of obesity and enable more precise herbal medicine prescriptions.

Procedure and Document Format for Requesting Construction of Local Administrative Offices by each Province in the 1930s (1930년대 각도의 지방행정관청사 건축요구 절차 및 문서형식)

  • Kim, Myungsun
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.22 no.6
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    • pp.43-49
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    • 2021
  • During the Japanese colonial period in Korea, the Choson Governor-General was a kind of state organ. At that time, for a local administrative office to be built, each province('Do') had to go through a certain administrative procedure and be approved by the Choson Government-General. In addition, it was necessary to receive financial support from the Choson Governor-General in the name of "state assistance" because the financial conditions of each province were not sufficient. To obtain this approval and financial support, the administrative procedure was divided into the first half, where each province requested the construction of a local administrative office, and the second half, where the Choson government-general approved it and supported it financially. There are studies on the first half procedure in 1914 and 1927, which were limited to the new construction of county('Goon') offices among several local administrative offices. This study analyzed the first half of the construction of all local administrative offices in the 1930s.

Factors and Sources of Regional Competitive Advantage: The Case of the Hospitality Industry of Jeju Island (지역의 경쟁우위 요인과 원천에 대한 연구: 제주지역 관광산업을 중심으로)

  • Yoon, Dong Jin
    • International Area Studies Review
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    • v.21 no.4
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    • pp.195-222
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    • 2017
  • This exploratory study analyses the factors, sources and effects of the regional competitive advantage of Jeju Island in Korea in global competition era. The competitive advantage of Jeju Province is analysed with the triple diamond model based on Porter's model for the competitive advantage of nations. The competitive advantage factors of Jeju Province are measured through the competitive advantage of the hospitality industry, which is one of the major industries of Jeju Island. These factors include outstanding natural landscape, domestic hospitality industry workforce, social overhead capital, massive domestic and international tourists, growth of related industries such as duty free shops and casinos, and coincidences such as Jeju Olle trail construction and Chinese government's international travel approval. Since these factors are based on local, domestic and international management resources, this study suggests that obtaining such resources is critical among Jeju hospitality industry in gaining the competitive advantage. Although the competitive advantage of Jeju hospitality industry is increasing, the organic connections with the regional economy are required for improvements on Jeju residents' quality of life. This study examines the factors and origins of competitive advantages on a regional level instead of a national level, and further investigates how the characters and origins of these factors affect the local economy. The results suggest that the triple diamond model is suitable for evaluating the regional competitive advantages.

Determinants of Attitude toward the Electronic Wristband System to Tackle the Spread of COVID-19 -Focused on the Interaction between Class and Age- (코로나19 자가격리 안심밴드에 대한 태도 결정 요인 -계층과 연령의 상호작용을 중심으로-)

  • Lee, Jae-Wan
    • The Journal of the Korea Contents Association
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    • v.21 no.6
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    • pp.285-294
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    • 2021
  • This study analyzes the factors that determine the attitude toward the electronic wristband(smartband) to check the position of self-quarantine subjects due to COVID-19. Furthermore, I analyze the interaction of class and age among the factors that determine attitudes toward the electronic wristband. In this study, the attitude toward self-quarantine electronic wristband is analyzed as a binary logit model, focusing on class and age. As a result of the analysis, the middle class significantly agreed with the self-quarantine electronic wristband compared to the lower class, and the older the person, the more in favor. On the other hand, the interaction between the class and the age shows that the age weakens the positive effect on the attitude of the self-quarantine electronic wristband in the middle and upper middle classes. The implication of this study is that it is necessary to push for mandatory electronic wristband in areas with high proportion of high-aged people with positive attitude toward self-quarantine electronic wristband and in the same age group, the approval rate is low, so it is necessary to promote mandatory electronic wristband in areas where the vulnerable class is dense.

A Case Study on Performance Analysis of Antimicrobial Copper Film Attaching to Window for Responding to COVID-19 and Others (코로나19 등 대응을 위한 "유리창 부착용 항바이러스 동필름" 성능분석 사례연구)

  • Kim, Seong Je
    • Journal of Korean Society of Disaster and Security
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    • v.14 no.1
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    • pp.23-40
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    • 2021
  • In the era of the global coronal 19 pandemic, there is a risk of cross-infection in hospitals at the stage where treatments and vaccines are currently being developed and marketed, so individuals should enhance their acquired immunity and generalize their living systems by the performance of copper ions in the social environment. In order to prevent the spread of infection, the need for anti-bacterial film and its efficacy were analyzed through anti-viral performance tests based on research and development cases of worldwide and immemorial time. he Korea Construction Research Institute (KCL) has received anti-bacterial performance certification and anti-viral test scores from the "National Approval Performance Certification Agency." At the time, NCCP 43326 Human Corona virus (BetaCoV/Korea/KCDC03/2020), which was approved by the Centers for Disease Control and Prevention, was introduced to ensure that the activity rate of infected cells was satisfied in the anti-viral performance test. Anti-proliferation measures for the Corona 19 virus require a quality clinical trial study comparing the experimental group within the glass space where the antiviral copper film is constructed with the comparator of the same condition without copper film.

A Study on Aadjustment of the Patterns, and the Correlation between the Diagnostic Tool for Climacteric and Postmenopausal Syndrome Pattern Identification (CaPSP) and Korean Medicine Doctors' Diagnosis (갱년기장애 및 폐경기 후 증후군 변증진단 도구의 변증분류 조정과 진단의 간의 진단일치도 연구)

  • Lee, In-Seon;Kim, Jong-Won;Jeon, Soo-Hyung;Chi, Gyoo-Yong;Kang, Chang-Wan
    • The Journal of Korean Obstetrics and Gynecology
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    • v.34 no.1
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    • pp.1-14
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    • 2021
  • Objectives: We studied for the adjustment of the patterns of 'The Diagnostic Tool for Climacteric and Postmenopausal Syndrome Pattern Identification (hereinafter CaPSPI)' (studyI) and the correlation between CaPSPI and Korean medicine doctors' diagnosis which was carried out without knowing the results of CaPSPI (studyII). Methods: The studyI followed the previous study method in 2018 (2018-3). The studyII was conducted from June 1, 2019 to July 10, 2020 with ◯◯ University Korean Medicine Hospital IRB's approval (2019-4). Doctors' diagnosis was conducted face-to-face with the subjects. Doctors' diagnosis was carried out based on the Kupperman's questionnaire, 'Diagnosis System of Oriental Medicine (hereinafter DSOM)' and four examinations (四診) records. The diagnosis was marked with 0 for 'no', 1 for 'somewhat', 2 for 'yes' and 3 for 'very yes'. The correlation between CaPSPI and the mean of doctors diagnostic scores were investigated statistically. Results: The studyI showed that heart-heat (心火) pattern was added. The Factor loading coefficient for heart-heat was 0.551 to 0.789, and the Cronbach's coefficient was 0.896. The studyII showed that the diagnosis (Kappa statistic) of two doctors showed statistically significant concordance (all eight patterns), with correlation of them were 0.3 or higher. And the correlation between the CaPSPI score and the mean of doctors' diagnostic score showed a statistically significant correlation, with liver qi depression (肝鬱) being the highest at 0.552 and dual deficiency of the heart-spleen (心脾兩虛) being the lowest at 0.301. Conclusions: Since the diagnosis results of CaPSPI showed a significant correlation with the diagnosis of Korean traditional medicine experts, it was believed that the CaPSPI results can be trusted and used for clinical purposes.

Nursing Students' Attitudes toward Abortion and Perceptions of Euthanasia and Good death (간호대학생의 낙태에 대한 태도와 안락사 및 좋은 죽음에 대한 인식)

  • Kim, Kyung sook
    • Journal of Convergence for Information Technology
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    • v.11 no.3
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    • pp.68-76
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    • 2021
  • This study was attempted to understand the relationship between the attitudes toward abortion, euthanasia, and the level of perception of good death among nursing college students and related factors. The data were collected by using structured questionnaires and the subjects were selected in C and G city. The research method was a descriptive research study, and the mean, standard deviation, frequency analysis, and Pearson's correlation coefficients were analyzed for the variables. The results of this study are as follows. The degree of support for the abortion opposition was 2.51±.56 (score range 1-4), and the opposition to abortion was superior to the approval..The perception of euthanasia was 3.06±.47 points (4 point scale), which was positively recognized at a higher level than the middle, and the good death perception was 2.97±.47 points (4 point scale), which was moderate. 97.1% of the respondents said that they had abortion decisions, and 5.7% of the university students experienced abortion. The attitude toward abortion showed negative correlation with the attitude toward euthanasia (r=-.374, p<.001), showing that the more supportive the anti-abortion, the more positive the attitude toward euthanasia. Therefore, it is necessary to educate the subjects to protect and respect the human rights of patients based on the dignity of life and humanistic thinking while providing nursing services.

Vascular plant diversity of Gwangdeoksan Mountain (Cheonan-Asan, Korea): insights into ecological and conservation importance (광덕산(천안·아산시) 관속식물상의 다양성: 생태학적, 보존학적 중요성)

  • JEON, Ji-Hyeon;CHO, Myong-Suk;YUN, Seon A;GIL, Hee-Young;KIM, Seon-Hee;KWON, Youl;SEO, Hee-Seung;SHUKHERTEI, Ariun;KIM, Seung-Chul
    • Korean Journal of Plant Taxonomy
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    • v.51 no.1
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    • pp.49-99
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    • 2021
  • Gwangdeoksan Mountain (699.3 m) is the highest border mountain between the two cities of Chungcheongnamdo Province, Cheonan and Asan, Korea. In this study, we investigated the flora of Gwangdeoksan Mt. from April of 2015 to October of 2017. Through 20 independent field investigations, we identified and tallied a total of 428 species, 9 subspecies, 30 varieties, and a forma in 287 genera and 97 families. Of a total of 468 taxa, 128 taxa in 112 genera and 58 families were found to be Korean endemic species (7 taxa), floristic regional indicator species (45 taxa), rare or endangered species (3 taxa), species subject to the approval of outbound transfer (73 taxa), and alien or ecosystem disturbing species (32 taxa). The flora of Gwangdeoksan Mt. can be divided into four distinct floristic subregions, with higher diversity in the north-facing subregion. The complex flora of Gwangdeoksan Mt., emerging at the edge of two floristic regions of the Korean peninsula, may represent a significant conservation priority and a topic for future ecological and geographical studies.

The Flora of Vascular Plants in Mt. Ilimsan and Its Adjacent Areas (in Boseong-gun, Jeonnam-do, Korea) (전남 보성군 일림산 일원 관속식물상)

  • Shin, Soon-Ho;Oh, Chan-Jin;You, Han-Choon
    • Korean Journal of Environment and Ecology
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    • v.36 no.3
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    • pp.277-302
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    • 2022
  • This study aims to establish the floristic data and identify the useful plant resources of Mt. Ilimsan and its adjacent areas. The survey was conducted 27 times from March 31, 2020 to August 22, 2021. It identified 500 taxa consisting of 101 families, 304 genera, 444 species, 11 subspecies, 42 varieties, and 3 formas. A total of 853 plant specimens were collected. There were 16 taxa designated as endemic plants and 7 taxa designated as the rare plants by the Korea Forest Service, and 5 taxa designated as the red list plants by the Ministry of Environment. Moreover, the floristic target species by the Ministry of the Environment found in this mountain were 69 taxa, including 49 taxa for floristic degree I, 7 for floristic degree II, 11 for floristic degree III, and 2 for floristic degree IV. Biological resources subject to export approval by the Ministry of Environment were 159 taxa. The alien plants were 49 taxa, of which 5.6 percent were naturalized, and the urbanization index was 7.9 percent. Ecosystem-disturbing invasive alien plants designated by the Ministry of Environment were 6 taxa.

A Study on the Development Trends of Polymer Electrolyte Membrane Fuel Cells and Application to Ships (국내외 PEMFC 개발 동향 및 선박 적용에 관한 고찰)

  • Lee, Chang-Yong
    • Journal of the Korean Society of Marine Environment & Safety
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    • v.28 no.4
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    • pp.657-666
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    • 2022
  • The International Maritime Organization(IMO) recommends the active implementation of national policies on technological development and energy efficiency to reduce Green House Gas (GHG) in the international shipping sector. Such IMO environmental regulation policies have a great impact on the entire shipping sector and are also a heavy burden on ship's owners. The most reasonable way to curb GHG emissions from ships comes down to the development of zero-emission ships. In other words, the development of a fuel cell ship (FCS) driven by an eco-friendly fuel is an alternative that can escape the IMO regulations. Countries in Asia, Northern America, and Europe independently develop and produce PEMFC, and are pursuing international standardization by acquiring approval in principle from an internationally accredited registration authority. Currently, there are three types of fuel cells (FC) that are recommended for ships: a Polymer Electrolyte Membrane Fuel Cell (PEMFC), a Molten Carbonate Fuel Cell (MCFC), and a Solid Oxide Fuel Cell (SOFC). In this study, PEMFC, which is expected to grow continuously in the global FC market, was analyzed domestic and international development trends, specifications, performance, and empirical cases applied to ships. In addition, when applying PEMFC to ships, it was intended to suggest matters to be considered and the development direction.