• Journal of the Korean Magnetic Resonance Society
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• v.5 no.1
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• pp.29-36
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• 2001

The structures of two VBS (viral binding site) RNAs, SL1 and SL2, of Yeast Saccharomyces cerevisiae vims have been studied by 2D and 3D NMR experiments. VBSs play a crucial role in viral particle binding to the plus strand and packaging of the RNA. The secondary structures of the two VBS RNAs share a common feature of the stem-internal loop-stem-hairpin loop structure although the size of the internal loops of SL1 and SL2 differs. 2D experiments were sufficient for fill assignments of SL1. However, isotope labeling of the sample and multidimensional experiments were required for 28-nucleotide-long SL2 due to the spectral overlap. Several 3D HCCH experiments have accomplished full assignment of SL2 RNA.

• Journal of The Korean Association For Science Education
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• v.25 no.3
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• pp.346-352
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• 2005

The purpose of this study was to develop problem-solving experiments and investigate the effects of these experiments on student attitudes. According to results the experiments were effective in changing student attitude from 'dead reckoners' to 'empiricists'. In addition, these experiments effectively changed perceptions about experiments, especially in the sub-categories of difference recognition, degree of inquiry, and use of debate.

• Asian Journal of Turfgrass Science
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• v.2 no.1
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• pp.5-30
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• 1988

The object of this experiments was to know the salt tolerance of Fults and other lawn grasses. Fults, Olympic (Tall fescue, Festuca arundinacea Schred), Ceeping red fescue, Kentucky bluegrass and Zoysia grass (Z. japonica S.) were grown in hydroponics with vermiculite at various concentrations of NaCl. Hoagland's solution was used as the basic solution (control), and the concentrations of Cl to it were 1000, 2000, 3000, 4000 and l5OOOppm, respectively. Each was cultivated under the circumstances during 2 months. The results obtained are summarized as follows: 1.The growth of Fults, Olympic, Creeping red fescue and others were better at Cl lOOOppm than control. In the 5OOOppm application, Fescues become worse and 23.9% of them were withered. In concentration of Cl above 9OOOppm, it was impossible to live. 2.In the l0000~l1000ppm application, Olympic and Kentucky bluegrass were become worse and most of them died. 3.Fults were almost possible to live in the below of 9OOOppm, but they began to die in the above of 10000 ppm. 4.With the increasing concentration of Cl, plants were dwarfed and the number of stems, leaves and roots were reduced, but it was especially observed that the number of stolons of Creeping red fescue were increased at 1000~4000ppm. 5.Fults grass was the most salt tolerant turfgrass, but was impossible to live at salt level of about 36 millimhos (Exchange NaCI conductivity-ppm). Among the grasses, according to salt tolerance, they were arranged as follows. Fults > Zoysia japonica S. > Ky belugrass > Olympic grass > Creeping red fescue 6.The number of leaves, stems, tillers, and dry weight of Olympic grass, Fults and others were increased more at Cl 1OOOppm application than control, but in the above 4OOOppm application, those of plants were decreased. 7.The productivity of all grasses under the experiments was increased at 3.l75millimhos (Exchange NaCi conductivity ppm) in the concentration of Cl. The each dry-weight of Olympic, Creeping red fescue, Kentucky bluegrass and Zoysia grass was decreased at 8.85millimhos, and the weight of Fults grass was also decreased remarkably at 12.20millimhos. 8.As the result of this experiments, most plants grow normally at low concentration of NaCI-l000ppm. That seems to stimulate more the grasses to grow than non-salt.

• Proceedings of the KSR Conference
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• 2004.10a
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• pp.510-515
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• 2004

In this study, we investigate the mechanical properties of rail pad material according to pad types. Especially, to study the application and endurance of TEEE material, we conducted experiments such as tension strength test, hardness test, fatigue test and wear test. Test results showed that TEEE material was better application and endurance than other pad material, but there was difficulties for comparing with others because the variations of application according to pad' types were variable.

• IE interfaces
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• v.22 no.1
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• pp.95-103
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• 2009

During the past few years, design of experiments (DOE) has been gaining acceptance in the telecommunications research community as a mean for designing and analyzing experiments economically and efficiently. In addition, the need for introducing a systematic robust design methodology (i.e., one of the most popular DOE methodologies) to network simulations has been increasing. In this paper, we present an architecture of voice over IP (VoIP) application and the E-Model for calculating the perceived quality of service (QoS). Then, we apply the Taguchi robust design methodology to optimize the perceived QoS of VoIP application, and describe the detailed step-by-step procedures. We have used ns-2 simulator to collect experimental data in which the SN ratio, a robustness measure, is analyzed to determine an optimal design condition. The analysis shows that "initial delay time in playout buffer" is a major control factor for ensuring robust behaviors of the perceived QoS of VoIP. Finally, we verify the proposed optimal design condition using a confirmation experiment.

• Journal of Korean Elementary Science Education
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• v.30 no.2
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• pp.152-161
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• 2011

The purpose of this study is to diagnose difficulties and problems that the preservice teachers experience when teaching inquiry-based classes in elementary science and to improve their professionalism through prescriptive instruction consulting utilizing PDRE (preparation, diagnosis, reflective implementation, evaluation) model. The result of this study was as follows. First, preservice teachers considered themselves to be lack of scientific knowledge, but this study confirmed that the application of instruction consulting improved their understandings in scientific concepts and principles and corrected their misconceptions. Second, preservice teachers experienced difficulties in variables that might influence the results of experiments, cautions for the experiments and unexpected results of experiments, and this consulting allowed them to gain instruction ability to cope with such circumstances and solve problems effectively. Third, preservice teachers experienced difficulties in applying instructional model into their classes and preparing lesson plans, but consulting actually made limited but positive changes in their abilities. However, from a longer-term perspective, quantitative increase in their teaching opportunities, the development and distribution of example manuals, and the utilization of various class materials provided by the assistant centers for teaching and learning should be achieved side by side.

• Transactions of the Korean Society of Mechanical Engineers A
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• v.26 no.7
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• pp.1348-1356
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• 2002

The present work concerns the optimal design for injection molding processes by using the design of experiments (DOE) and numerical analysis. The DOE approaches is planned to be able to consider two-way interaction, and have been applied progressively for both mold design and process design. Numerical analyses have been carried out as a design of experiments for mold parameters such as runner specifications and cooling channel configurations. In order to determine optimal process parameters, experiments have been performed for various process conditions with the DOE scheduling. As a result, the quality and productivity of the product have been improved, and the proposed approach can be successfully reflected on the industrial injection molding process of precision electronics parts.

• Transactions of the Korean Society of Machine Tool Engineers
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• v.14 no.6
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• pp.125-131
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• 2005

The purpose of this study is an optimization of gate valve made by forging method instead of welding method. In this study, we propose an optimal shape design to improve the mechanical efficiency of gate valve. In order to optimize more efficiently and reliably, the meta-modeling technique has been developed to solve such a complex problems combined with the DACE (Design and Analysis of Computer Experiments). The DACE modeling, known as the one of Kriging interpolation, is introduced to obtain the surrogate approximation model of the function. Also, we prove reliability of the DACE model's application to gate valve by computer simulations using FEM(Finite Element Method).

• Transactions of the Korean Society of Machine Tool Engineers
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• v.17 no.4
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• pp.35-41
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• 2008

R/In order to satisfy the customer's variant needs for a product quality in recent years, a demand for developing higher precision machining technologies in a lot of application areas such as automobile, cellular phone and semiconductor has been increased more and more. Magnetic abrasive polishing(MAP) process is one of these precision technologies. In this study, to verify the parameters' effect of the MAP process on the surface roughness improvement of the plane and the inclined workpiece, well planned experiments which was called the design of experiments were carried out. Considered polishing factors were spindle speed, supplied current, abrasive type and working gap between the workpiece and the solid tool. As a result, it was seen that the supplied current and the working gap greatly affected the surface roughness improvement.

• Genomics & Informatics
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• v.18 no.2
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• pp.18.1-18.5
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• 2020

Finding publications that propose alternative methods to animal experiments is an important but time-consuming task since researchers need to perform various queries to literature databases and screen many articles to assess two important aspects: the relevance of the article to the research question, and whether the article's proposed approach qualifies to being an alternative method. We are currently developing a Web application to support finding alternative methods to animal experiments. The current (under development) version of the application utilizes external tools and resources for document processing, and relies on the PubAnnotation ecosystem for annotation querying, annotation storage, dictionary-based tagging of cell lines, and annotation visualization. Currently, our two PubAnnotation repositories for discourse elements contain annotations for more than 110k PubMed documents. Further, we created an annotator for cell lines that contain more than 196k terms from Cellosaurus. Finally, we are experimenting with TextAE for annotation visualization and for user feedback.