• 대한치과기공학회지
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• 제39권3호
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• pp.145-152
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• 2017

Purpose: This study sought to identify changes in the mechanical characteristics and color of zirconia according to different sintering temperatures of the substance. Methods: This study processed some specimens of zirconia into those of $8mm(H){\times}10mm(W){\times}50mm(L){\pm}0.1$ each, and sintered them at $1450{\sim}1600^{\circ}C$ on a $50^{\circ}C-interval$ basis in order to examine how their mechanical characteristics and color are changed. Each specimen sintered using the spectral colorimetric apparatus (Easyshade, VITA, Germany) was observed for each of the color change by sintering temperature. Results: When those specimens were sintered at $1450{\sim}1600^{\circ}C$, they were 0% in absorption ratio and porosity, 20% in shrinkage ratio and $6.10g/cm^3$ in specific gravity. Absorption ration, porosity, shrinkage ratio and specific gravity all didn't vary depending on the sintering temperature. The fracture strength of the specimens was highest or 1037MPa at the sintering temperature of $1550^{\circ}C$ and a little lower or 989MPa at that of $1600^{\circ}C$. No variation in L* value was found depending on the sintering temperature of the specimens, while c* value was highest at that of $1450^{\circ}C$. In addition, h* value was highest when the specimens was sintered at $1550^{\circ}C$. Conclusion: This study could determine how zirconia shows changes in mechanical characteristics and color in accordance with different temperatures of its sintering. It is necessary to supplement the physical data of colored transparent zirconia block which is expected to be widely used in clinical practice.

• 약학회지
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• 제57권3호
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• pp.205-212
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• 2013

Dissolution test has been performed to control drug quality and to predict in vivo drug release profile of solid dosage forms, so there's a drift towards setting dissolution test instead of disintegration test. However, some solid dosage forms in Korea Pharmaceutical Codex (KPC) are not established the dissolution test yet, so these monographs are necessary to set the specification of dissolution test. In this study, we developed the specification and test method of dissolution test for itopride hydrochloride tablets and tiropramide hydrochloride tablets which are not established the dissolution test yet. According to the "Manual for Guideline Application for Validation of Analytical Procedures" and "Guidelines on Specification of Dissolution test for Oral dosage form" of Korean Pharmacopoeia (KP), we validated and established each development method. Based on the preliminary dissolution profile, we set the dissolution condition(paddle apparatus, pH 1.2 media, 50 rpm). For this condition, we performed the main dissolution test to determine the specification (45 min, 85%). Finally, we validated each analytical method by specificity, linearity, accuracy and precision. These developed methods will be included the next supplement of KPC and also contributed to the quality control of medicines.

• 한국언론정보학보
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• 제33권
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• pp.169-191
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• 2006

이 연구에서는 방송광고 판매제도 개선에서의 경쟁도입이 각 매체의 광고수입에 미치는 영향을 분석하고, 그에 기초해 바람직한 제도개선을 위한 제도적 장치를 추론코자 하였다. 경쟁도입은 방송광고 요금인상과 방송광고비 증가를 초래하며, 이로 인한 사회적 부작용을 제어할 장치가 없다면 언론매체의 다양성과 균형발전이 훼손되고, 여론의 독과점이 촉진되는 부작용을 피할 수 없다. 따라서 방송광고판매에 경쟁체제를 도입하되, 방송법이 규정한 방송의 제작편성과 광고영업의 제도적 분리를 실질적으로 담보할 수 있는 제도적 장치와, 방송광고 요금의 인상과 그로 인한 방송광고비의 증가를 사회적으로 조절할 수 있는 제도적 장치를 갖추는 것이 필요하다. 그 제도적 장치들은 다음과 같은 다섯 가지이다. 첫째, 방송광고 거래의 투명성과 공정성을 유지하는 것이다. 둘째, 방송사의 직접적 광고영업을 금지하고 더 나아가 직접영업 효과를 차단하는 것이다. 셋째, 공영방송이 공적서비스에 전념할 수 있도록 관련 정책을 정비 개선하는 것이다. 넷째, 광고시장에 대한 사회적 개입수단을 운용하는 것이다. 다섯째, 지역방송과 종교방송 등이 공적인 기본 기능을 수행할 수 있도록 최소한의 재원을 적절히 보장하는 것이다.