• Journal of Technologic Dentistry
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• v.39 no.3
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• pp.145-152
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• 2017

Purpose: This study sought to identify changes in the mechanical characteristics and color of zirconia according to different sintering temperatures of the substance. Methods: This study processed some specimens of zirconia into those of $8mm(H){\times}10mm(W){\times}50mm(L){\pm}0.1$ each, and sintered them at $1450{\sim}1600^{\circ}C$ on a $50^{\circ}C-interval$ basis in order to examine how their mechanical characteristics and color are changed. Each specimen sintered using the spectral colorimetric apparatus (Easyshade, VITA, Germany) was observed for each of the color change by sintering temperature. Results: When those specimens were sintered at $1450{\sim}1600^{\circ}C$, they were 0% in absorption ratio and porosity, 20% in shrinkage ratio and $6.10g/cm^3$ in specific gravity. Absorption ration, porosity, shrinkage ratio and specific gravity all didn't vary depending on the sintering temperature. The fracture strength of the specimens was highest or 1037MPa at the sintering temperature of $1550^{\circ}C$ and a little lower or 989MPa at that of $1600^{\circ}C$. No variation in L* value was found depending on the sintering temperature of the specimens, while c* value was highest at that of $1450^{\circ}C$. In addition, h* value was highest when the specimens was sintered at $1550^{\circ}C$. Conclusion: This study could determine how zirconia shows changes in mechanical characteristics and color in accordance with different temperatures of its sintering. It is necessary to supplement the physical data of colored transparent zirconia block which is expected to be widely used in clinical practice.

• YAKHAK HOEJI
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• v.57 no.3
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• pp.205-212
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• 2013

Dissolution test has been performed to control drug quality and to predict in vivo drug release profile of solid dosage forms, so there's a drift towards setting dissolution test instead of disintegration test. However, some solid dosage forms in Korea Pharmaceutical Codex (KPC) are not established the dissolution test yet, so these monographs are necessary to set the specification of dissolution test. In this study, we developed the specification and test method of dissolution test for itopride hydrochloride tablets and tiropramide hydrochloride tablets which are not established the dissolution test yet. According to the "Manual for Guideline Application for Validation of Analytical Procedures" and "Guidelines on Specification of Dissolution test for Oral dosage form" of Korean Pharmacopoeia (KP), we validated and established each development method. Based on the preliminary dissolution profile, we set the dissolution condition(paddle apparatus, pH 1.2 media, 50 rpm). For this condition, we performed the main dissolution test to determine the specification (45 min, 85%). Finally, we validated each analytical method by specificity, linearity, accuracy and precision. These developed methods will be included the next supplement of KPC and also contributed to the quality control of medicines.

• Korean journal of communication and information
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• v.33
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• pp.169-191
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• 2006

Changing our monopoly broadcasting advertising system into free competition system may give rise to serious troubles that intensify commercialism of broadcasting and reduce diversity of public opinion. In the boundaries of public interest out of danger, korean broadcasting system should adopt a system that partially adopts the principle of free market. Broadcasting advertising sale system affect the whole broadcasting system because it functions as an effective capital-resource provider. Thus, it affects the broadcasting policies' righteousness and efficiency. Due to the non-elastic nature of the total advertising market, broadcasting advertising's size affects other media's capital allocation process. Therefore, broadcasting advertising sales system not only affects broadcast's social duty and public interest, but also affects the whole media industry. First, provide fair and open-competitive measures to support broadcast sales policy so that the market-based system can be run smoothly. Second, block any un-due influence from advertisers by separating production/programming and advertising sales. Third, sustain public broadcast system, not based on the advertising sales but based on the subscription fee. Fourth, social intervention of the advertising market. Fifth, provide policies that can set up multiple media channels/outlets and public opinion. By providing the minimum capital resources to the public broadcasting system, the broadcasting system can act on its public-interest duty and support the people's right-to-know rights.