• Korean Journal of Organic Agriculture
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• v.25 no.1
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• pp.187-201
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• 2017

This study was conducted to elucidate the effect of mulching materials on growth characteristics, saponin contents and antioxidant activity of Platycodin grandiflorum Ridix roots for organic farming. Plastic film, sawdust and rice bran were treated by mulching with several different methods after transplanting P. grandiflorum Radix. In root length, when plastic film plot, sawdust plot and rice bran plot were treated, root length was recorded the highest scores (24.0~27.5 cm) in plastic film plot and sawdust plot. Root width was recorded the highest score (30.0 mm) in plastic film plot. Also, the number of fine-roots was the highest in plastic film plot (36.0). Fresh weight, which affects directly yield, was the highest in plastic film plot (130 g/plant). The contents of platycodin D3 and deapioplatycodin D were shown to 111.2 and 48.1 mg/100 g, the highest values were observed in sawdust plot. The total polyphenol and flavonoid contents were recorded the highest scores (11.0 and 8.6 mg/g, respectively) in plastic film plot. In this study we confirmed that there were differences among mulching materials in growth characteristics, saponin contents and antioxident activity of P. grandiflorum roots.

• Journal of the Korean Society of Tobacco Science
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• v.15 no.1
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• pp.3-14
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• 1993

Oxidants in environment or cigarette smoke are known to be implicated in the oxidative damages of pulmonary system. Such cellular damages are prevented by the presence of adequate levels of antioxidants in the tissue. In the present study, we investigated the influences of smoking duration and concentration of smoke on lung antioxidant defense in rats. Subchronic exposure of rats to smoke generated from 6 cigarettes per day for 90 days caused the activities of catalase and superoxide dismutase (SOD) to increase. However, glutathione peroxidase (GP-Xase) was not significantly changed. Total sulfhydryl compounds (Total-SH) in the lung homogenates from the rats inhaled with cigarette smoke for 15 days was decreased by 44% , thereafter it was returned to the level of normal rats. On the contrary, when rats were daily exposed to a different concentration of smoke generated from 1 to 20 cigarettes per day for 15 days, the activity of catalase was increased gradually with dose, but total SOD activity was increased only in the rats of low dose groups less than 5 cigarettes. Three types of SOD (one Cu, Zn-SOD with pI 4.9, and two Zn-SOD with pI 4.7 and 7.9)were detected in the lung homogenates and Zn-SOD with pI 4.7 was the major and cigarette-smoke inducible form. These results indicate that the protection of lung against oxidants from cigarette smoke seems to be accomplished by the induction of catalase and SOD, especially a cyanide resistant Zn-SOD with pI 4.f, following the consumption of antioxidants such as GSH in the beginning of inhalation period.

• The Korea Journal of Herbology
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• v.26 no.3
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• pp.37-45
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• 2011

Objectives : This study focused on Schisandrae Fructus (SF) and Perilae Folium (PF), traditional medicine herbs and health functional food in Korea, Japan and China. We investigated various pharmacological activities that include a potential source of free radical scavenging, anti-viral, anti-microbial, anti-allergy and anti-inflammatory activities. Methods : We conducted an investigation of total contents of phenolic and flavonoid compounds in these single herbal extraction with/without combined to mixture. We also measured antioxidant activities such as DPPH free radical scavenging, SOD-like scavenging, nitrite scavenging and hydroxyl radical scavenging activities, xanthine oxidase inhibition, linoleic acid peroxidation inhibition, and reducing power. Results : As the results, contents of total phenoilc compounds and flavonoids were higher in those of PF than those of SF. Those of SF+PF mixture showed the synergy effects compared with those of SF and PF single extractions. Activities of DPPH free radical and SOD-like scavenging in 1 mg/mL concentration increased in dose dependent manners. That of SF increased compared with that of PF. That of SF and PF mixture also increased compared with that of BHA as a positive control. The other antioxident activities also showed similar to patten of activity of DPPH free radical scavenging. When combined to SF and PF extractions, there was showed synergic effect compared with those of BHA, excepted activities of xanthine oxidase inhibition and reducing power. Taken together, SF and PF have high phenolic and flavonoid compounds content furthermore, antioxidant activities in SF and PF mixture showed more synergy effect compared with those of BHA. Conclusions : Therefore, these findings suggest that SF and PF mixture may offer functional materials potential for development of functional beverage. But further studies are needed for the identification of the active compounds.