• 제목/요약/키워드: annual report

검색결과 379건 처리시간 0.029초

E형 간염 바이러스에 의한 제 1형 인터페론 신호전달분자 활성 억제 (Hepatitis E Virus Inhibits Activation of Signaling Molecules Involved in Induction of Type I Interferon)

  • 명진종
    • 한국미생물·생명공학회지
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    • 제46권4호
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    • pp.320-325
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    • 2018
  • E형 간염바이러스는 전세계적으로 매년 2천만건의 감염을 일으키는 것으로 알려져 있다. 흥미로운 것은 임산부에서 특히 높은 치사율을 보이는데, 무려 20-30%의 사망률을 보인다는 점이다. 면역능이 있는 감염환자에서는 E형 간염바이러스 감염은 별다른 증상 없이 자연 치유되지만, 면역능이 낮은 에이즈환자나 고령환자에서는 만성감염을 일으킬 수도 있으며 사망에 이르게 할 수도 있다. 따라서, E형 간염바이러스의 증식억제에 면역반응의 중요성이 높으며, 특히 인터페론 반응이 중요한 역할을 할 것으로 사료된다. 본 연구팀은 E형 간염바이러스의 프로티아제가 RIG-I 의존적 제 1형 인터페론 반응을 유의미하게 억제하는 것을 관찰하였다. 또한 바이러스 프로티아제가 RIG-I의 하위 신혼전달 분자의 하나인 MAVS의 활성도 농도 의존적으로 억제하는 것으로 분석하였다. E형 간염바이러스에 의한 제 1형 인터페론 반응 억제의 구체적인 작용 기작을 밝힌다면 효과적인 항바이러스제제의 개발의 초석을 놓을 수 있을 것으로 기대된다.

LULUCF 부문 산림 온실가스 인벤토리 구축을 위한 Sampling과 Wall-to-Wall 방법론 비교 (Comparison of Sampling and Wall-to-Wall Methodologies for Reporting the GHG Inventory of the LULUCF Sector in Korea)

  • 박은빈;송철호;함보영;김지원;이종열;최솔이;이우균
    • 한국기후변화학회지
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    • 제9권4호
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    • pp.385-398
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    • 2018
  • Although the importance of developing reliable and systematic GHG inventory has increased, the GIS/RS-based national scale LULUCF (Land Use, Land-Use Change and Forestry) sector analysis is insufficient in the context of the Paris Agreement. In this study, the change in $CO_2$ storage of forest land due to land use change is estimated using two GIS/RS methodologies, Sampling and Wall-to-Wall methods, from 2000 to 2010. Particularly, various imagery with sampling data and land cover maps are used for Sampling and Wall-to-Wall methods, respectively. This land use matrix of these methodologies and the national cadastral statistics are classified by six land-use categories (Forest land, Cropland, Grassland, Wetlands, Settlements, and Other land). The difference of area between the result of Sampling methods and the cadastral statistics decreases as the sample plot distance decreases. However, the difference is not significant under a 2 km sample plot. In the 2000s, the Wall-to-Wall method showed similar results to sampling under a 2 km distance except for the Settlement category. With the Wall-to-Wall method, $CO_2$ storage is higher than that of the Sampling method. Accordingly, the Wall-to-Wall method would be more advantageous than the Sampling method in the presence of sufficient spatial data for GHG inventory assessment. These results can contribute to establish an annual report system of national greenhouse gas inventory in the LULUCF sector.

Performance Analysis of Islamic Banks in Indonesia: The Maqashid Shariah Approach

  • MURSYID, Mursyid;KUSUMA, Hadri;TOHIRIN, Achmad;SRIYANA, Jaka
    • The Journal of Asian Finance, Economics and Business
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    • 제8권3호
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    • pp.307-318
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    • 2021
  • The objective of this study is to analyze the performance of Islamic banks with the Maqashid Shariah approach. The analysis technique used is the Simple Additive Weighting Method (SAW) to solve multi-attribute decision problems. The sampling technique used was purposive sampling while the data came from the annual report of each bank. The results showed that the BTPN Shariah (BTPNS) and Bank Muamalat Indonesia (BMI) are ranked first and second respectively on the Maqashid Shariah Index (MSI) with values of 0.265429 and 0.237110 respectively. Panin Dubai Shariah Bank (PDSB) ranked third with an MSI value of 0.180733, followed by BCA Shariah which ranked fourth with an MSI value of 0.151299. BRI Shariah ranked fifth with an MSI value of 0.128606, followed by BNI Shariah which ranked sixth with an MSI value of 0.124661. Bank Mega Shariah ranked last with an MSI value of 0.087068. Furthermore, there is a relationship (correlation) between ROE, ROA, and OEOI and MSI since each data has a value of 0.000, 0.000, 0.050, and 0.001 respectively, which is smaller than the significance value of 0.05. On the other hand, NPF, TPF, and Asset Growth Rates do not correlate with the MSI since each data has a value of 0.051, 0.252, and 0.215 respectively which is greater than the significance value of 0.05.

Sentinel-2 위성영상을 이용한 DMZ 산불 피해 면적 관측 기법 연구 (The Study of DMZ Wildfire Damage Area Detection Method Using Sentinel-2 Satellite Images)

  • 이슬기;송종성;이창욱;고보균
    • 대한원격탐사학회지
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    • 제38권5_1호
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    • pp.545-557
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    • 2022
  • 본 연구는 직접적인 접근이 어려운 demilitarized zone (DMZ)의 산불 피해 지역을 파악하기 위하여, 고해상도 위성영상 및 머신러닝 기반의 감독 분류 기법을 이용하였다. 고해상도 위성 영상은 Sentinel-2 A/B를 이용하였으며, SVM 감독분류 기법을 기반으로 토지피복도를 산출하였다. DMZ 산불 피해 지역을 분류하기 위한 최적의 조합을 찾기 위하여 SVM 내에 다양한 커널과 밴드 조합에 따른 감독 분류를 진행하고 오차 행렬을 통해 정확도를 평가하였다. 또한, 2020년, 2021년은 위성영상 자료 기반의 산불 탐지 결과와 산불 연보의 피해 지역 면적 간의 비교를 통한 검증을 수행하였다. 이후, 현재 피해 면적 자료가 없는 2022년의 산불 피해 지역을 탐지함으로써 신뢰할 만한 수준의 결과를 신속적으로 파악하고자 하였다.

다시점 수어 데이터 획득 및 저장 시스템 설계 및 구현 (Design and Implementation of Data Acquisition and Storage Systems for Multi-view Points Sign Language)

  • 김근모;김봉재
    • 한국인터넷방송통신학회논문지
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    • 제22권3호
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    • pp.63-68
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    • 2022
  • 한국장애인개발원의 2021 장애통계연보 자료에 따르면 대한민국에 청각 장애를 가지고 있는 사람은 395,789명이 있다. 이러한 사람들이 청각 장애를 통해 많은 불편을 겪고 있고, 이를 해결하기 위해 수어 인식 및 번역에 관련된 많은 연구가 진행되고 있다. 수어 인식 및 번역 연구에서는 수어 데이터를 수집하는 것이 중요한 부분을 차지하고 있지만 한국어 수어 데이터는 전문적으로 수어를 사용하는 사람의 수가 많지 않아 많은 어려움이 있다. 또한 구축된 기존의 데이터들도 발화자의 정면에서 촬영된 수어 데이터가 대부분이다. 이와 같은 문제점을 해결하기 위해 본 연구에서는 하나의 시점이 아닌 다시점에서 수어 데이터를 실시간으로 수집하고 보다 활용 편의성이 높게 저장 및 관리할 수 있는 저장 시스템을 설계하고 구현하였다.

연도별, 업종별 업무상 사고사망자 특성 (Characteristics of Industrial Accident Deaths by Year and Industry)

  • 정혜선;곽수진;권은중;백은미
    • 한국직업건강간호학회지
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    • 제30권4호
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    • pp.186-195
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    • 2021
  • Purpose: The current status and rationale of industrial accidents needs to be examined to develop scientific and systemic preventive measures. Methods: The aim of this study is to analyze the current data on industrial accidents provided by the Ministry of Employment and Labor and categorize work-related deaths by types of industries and annual report. Results: First, the highest number of deaths occurred in industries that had less than 50 people. Second, in the manufacturing industry, the highest death rate was found in workers in the age group 50-59 years. In the construction industry, workers aged 50 and above had the highest number of deaths. In other industries, workers aged 60 and above had the highest number of deaths. Third, the highest number of deaths occurred in workers with less than one year of experience in any industry Fourth, in most industries, the highest work-related deaths occurred during weekdays (Monday~Friday). In 2015, the warehouse delivery industry had 33% higher work-related deaths on the weekends (Saturday and Sunday) as compared to other industries. Fifth, in most industries, the highest work-related deaths occurred from 8 AM to 6 PM. The warehouse delivery industry had higher work-related deaths from 10 PM to 8 AM as compared to other industries. Conclusion: In order to increase the efficacy of industrial accident prevention, it is necessary to establish an effective health management system and apply strict safety management activities.

Exposure of the Population in the United States to Ionizing Radiation

  • Carter Melvin W.;Oliver Robert W.
    • Journal of Radiation Protection and Research
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    • 제12권2호
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    • pp.37-50
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    • 1987
  • The exposure of the population in the United States to ionizing radiation has recently been evaluated by the National Council on Radiation Protection and Measurements (NCRP). This was done by constituting six organizational groups to address various phases of the work and the results of this work are summarized in this article. The article is based on the report, by the same title, which is scheduled for publication by the NCRP in September, 1987. The six organizational groups are titled Radiation Exposure from Consumer Products, Natural Background Radiation, Radiation Associated with Medical Examinations, Radiation Received by Radiation Employees, Public Exposure from Nuclear Power, and Exposure from Miscellaneous Environmental Sources. These titles are descriptive of the subject areas covered by each of these separate groups. The data evaluated are for the years 1977-1984 with the majority of the data being for the period 1980-1982. Summary information is presented and discussed for the number of people exposed to given sources, the effective dose equivalent, the average effective dose equivalent to the U.S. population, and the genetically significant dose equivalent. The average annual effective dose equivalent from all sources to the U.S. population is approximately 3.6 mSv (360 mrem). Exposures to natural sources make the largest contribution to this total. Radon and radon decay products contribute 2.0 mSv (200 mrem) whereas the other naturally occurring radionuclides contribute 1.0 mSv (100 mrem). Among man-made or enhanced sources, medical exposures make the largest additional contributions, namely 0.39 mSv (39 mrem) for diagnosis and 0.14 mSv (14 mrem) for nuclear medicine. It was not possible to evaluate exposures for therapy. Most of the other sources of population exposure, including nuclear power and consumer products, are minor. A possible exception would be the use of tobacco products. These exposures are discussed in relation to a negligible individual risk level of $10{\mu}Sv/y$ (1 mrem/y). The NCRP considers exposures below the negligible individual risk level as trivial and as such should be dismissed.

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우리나라 노인의 우울이 삶의 질 및 구강건강과의 관련성: 국민건강영양조사 제8기 1차년도(2019)자료 활용 (Relationship of depression with the quality of life and oral health ofthe elderly Koreans: data from the 8th National Health and Nutrition Examination Survey)

  • 김미정;김은희;임차영
    • 대한치위생과학회지
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    • 제5권2호
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    • pp.73-83
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    • 2022
  • Background: This study was aimed at reducing depression and improving the quality of life and oral health of the elderly Koreans by elucidating the effect of depression on their life quality and oral health. Methods: Original data from the 8th National Health and Nutrition Survey (2019) were analyzed and implemented. The elderly (age≥65years) Koreans were enrolled. The oral health status was determined using the Decayed, Missing, Filled Teeth (DMFT) index and subjective self-report. The quality of life was quantified as the sum of score of each item in the Euro Qol-5 dimension (EQ-5D) and Health-related Quality of Life Instrument with 8 Items (HINT-8). The t-test, one-way analysis of variance, correlation analysis, and multiple regression analysis were performed to statistically compare the quality of life, oral health status, and oral health status according to the depression status. Results: EQ-5D and HINT-8 scores differed significantly with the history of depression, current depression, stress perception, depression for 2 weeks, and annual suicidal intention (p≤0.05). The DMFT index score differed significantly with the depression diagnosis and depression for 2 weeks (p≤0.05). EQ-5D, HINT-8, and DMFT index differed significantly with all oral health behavior variables (p≤ 0.05). Conclusions: The results of this study could serve as a basis to formulate oral health programs for the elderly to reduce depression and improve the quality of life.

3D프린팅 산업 및 금속소재 사용시 유해인자 노출 연구 현황 (The Status of 3D Printing Industry and Researches on Exposure to Hazards When Using Metal Materials)

  • 박해동;허이준
    • 대한안전경영과학회지
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    • 제25권1호
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    • pp.7-14
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    • 2023
  • We attempted to provide an overview of the laws and current state of the 3D printing industry in South Korea and around the world, using the annual industry surveys and the Wohler report. Additionally, we reviewed articles relating to the potential exposure to hazards associated with 3D printing using metal materials. In South Korea, there were 406 3D printing-related businesses, employing 2,365 workers, and the market size was estimated at 455.9 billion won in 2021. Globally, the average growth rate of the 3D printing industry market over the past 10 years was 27.4%, and the market size was estimated at $11.8 billion in 2019. The United States had the highest cumulative installation ratio of industrial 3D printers, followed by China, Japan, Germany, and South Korea. A total of 6,168 patents related to 3D printing were registered in the US between 2010 and 2019. Harmful factors during metal 3D printing was mainly evaluated in the powder bed fusion and direct energy deposition printing types, and there is a case of material extrusion type with metal additive filaments. The number, mass, size distribution, and chemical composition of particles were mainly evaluated. Particle concentration increases during the opening of the chamber or post-processing. However, operating the 3D printer in a ventilated chamber can reduce particle concentration to the background level. In order to have a safe and healthy environment for 3D printing, it is necessary to accumulate and apply knowledge through various studies.

로지스틱 회귀분석모델을 활용한 평창군 진부 지역의 산사태 재해의 인명 위험 평가 (Life Risk Assessment of Landslide Disaster in Jinbu Area Using Logistic Regression Model)

  • 라하누마 빈테 라시드 우르미;알-마문;장동호
    • 한국지형학회지
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    • 제27권2호
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    • pp.65-80
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    • 2020
  • This paper deals with risk assessment of life in a landslide-prone area by a GIS-based modeling method. Landslide susceptibility maps can provide a probability of landslide prone areas to mitigate or proper control this problems and to take any development plan and disaster management. A landslide inventory map of the study area was prepared based on past historical information and aerial photography analysis. A total of 550 landslides have been counted at the whole study area. The extracted landslides were randomly selected and divided into two different groups, 50% of the landslides were used for model calibration and the other were used for validation purpose. Eleven causative factors (continuous and thematic) such as slope, aspect, curvature, topographic wetness index, elevation, forest type, forest crown density, geology, land-use, soil drainage, and soil texture were used in hazard analysis. The correlation between landslides and these factors, pixels were divided into several classes and frequency ratio was also extracted. Eventually, a landslide susceptibility map was constructed using a logistic regression model based on entire events. Moreover, the landslide susceptibility map was plotted with a receiver operating characteristic (ROC) curve and calculated the area under the curve (AUC) and tried to extract a success rate curve. Based on the results, logistic regression produced an 85.18% accuracy, so we believed that the model was reliable and acceptable for the landslide susceptibility analysis on the study area. In addition, for risk assessment, vulnerability scale were added for social thematic data layer. The study area predictive landslide affected pixels 2,000 and 5,000 were also calculated for making a probability table. In final calculation, the 2,000 predictive landslide affected pixels were assumed to run. The total population causalities were estimated as 7.75 person that was relatively close to the actual number published in Korean Annual Disaster Report, 2006.