• Wind and Structures
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• v.23 no.6
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• pp.505-521
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• 2016

The objective of this study is to investigate numerically the effect of building roof shaps on wind flow and pollutant dispersion in a street canyon with one row of trees of pore volume, $P_{vol}=96%$. A three-dimensional computational fluid dynamics (CFD) model is used to evaluate air flow and pollutant dispersion within an urban street canyon using Reynolds-averaged Navier-Stokes (RANS) equations and the Explicit Algebraic Reynolds Stress Models (EARSM) based on k-${\varepsilon}$ turbulence model to close the equation system. The numerical model is performed with ANSYS-CFX code. Vehicle emissions were simulated as double line sources along the street. The numerical model was validated by the wind tunnel experiment results. Having established this, the wind flow and pollutant dispersion in urban street canyons (with six roof shapes buildings) are simulated. The numerical simulation results agree reasonably with the wind tunnel data. The results obtained in this work, indicate that the flow in 3D domain is more complicated; this complexity is increased with the presence of trees and variability of the roof shapes. The results also indicated that the largest pollutant concentration level for two walls (leeward and windward wall) is observed with the upwind wedge-shaped roof. But the smallest pollutant concentration level is observed with the dome roof-shaped.

• Journal of the Korean Vacuum Society
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• v.21 no.5
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• pp.249-257
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• 2012

Nonlinear dynamical behaviors of plasma in the Pierce diode are investigated by a numerical code developed using a one dimensional fluid model. The plasma in Pierce diode is alternately stable and unstable as Pierce parameter is changed. The dynamical characteristics of neutral and non-neutral Pierce system is examined analytically and numerically. It alternately has growing and oscillatory mode as Pierce parameter varies. As Pierce parameter is decreased, each oscillatory mode undergoes a sequence of subharmonic period-doubling bifurcation and then culminate in a chaotic strange attractor. The analysis for this nonlinear behavior can be used as a model for understanding of beam-plasma interaction in more complex geometries and a data for chaos control.

• BMB Reports
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• v.50 no.3
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• pp.126-131
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• 2017

P48 Ebp1 is expressed in rapidly proliferating cells such as cancer cells and accelerates cell growth and survival. However, its expression pattern and role in central nervous system development have not been studied. Here, we demonstrated the spatiotemporal expression pattern of p48 Ebp1 during embryonic development and the postnatal period. During embryonic development, p48 Ebp1 was highly expressed in the brain. Expression gradually decreased after birth but was still more abundant than p42 expression after birth. Strikingly, we found that p48 Ebp1 was expressed in a cell type specific manner in neurons but not astrocytes. Moreover, p48 Ebp1 physically interacted with beta tubulin but not alpha tubulin. This fits with its accumulation in distal microtubule growth cone regions. Furthermore, in injured hippocampal slices, p48 Ebp1 introduction promoted axon regeneration. Thus, we speculate that p48 Ebp1 might contribute to microtubule dynamics acting as an MAP and promotes CNS axon regeneration.

• Transactions of the Korean Society of Mechanical Engineers B
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• v.24 no.6
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• pp.785-791
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• 2000

GDI (Gasoline Direct Injection) engines are considered as one of the candidates for next generation engines of passenger cars, which reduce exhaust emissions and fuel consumption. In GOI engines, a high-pressure gasoline supply system is required to directly inject the fuel to combustion chambers. Because of low lubricity of gasoline fuel, the clearance between a plunger and a barrel in GDI fuel pumps is too wide to achieve smooth hydrodynamic lubrication. Thus, it is difficult to generate high-pressure condition in GDI fuel pump since large amount of leakage flow occurs between the plunger and the barrel In this study, an optimum plunger design is presented to minimize leakage in the aspect of flow control. This paper analyzes leakage flow characteristics in the clearance to improve pumping performance of GDI fuel pumps. Effects of groove in the plunger are studied according to variations of depth and width. Evaluations of pumping performance are determined by the amount of pressure drop in the leakage path assuming a constant leakage flows. Both of turbulence and incompressible models are introduced in CFD (Computational Fluid Dynamics) analysis. Design parameters have been introduced to minimize leakage in limited space, and a methodological study on geometrical optimization has been conducted. As results of CFD analysis in various geometrical cases, optimum groove depths have been found to generate maximum sealing effects on gasoline fuel between the plunger and the barrel. This procedure offers a methodological way of an enhancement of plunger design for high-pressure GDI fuel pumps.

• BMB Reports
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• v.49 no.5
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• pp.245-246
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• 2016

The level and activity of critical regulatory proteins in cells are tightly controlled by several tiers of post-translational modifications. HIF-1α is maintained at low levels under normoxia conditions by the collaboration between PHD proteins and the VHL-containing E3 ubiquitin ligase complex. We recently identified a new physiologically relevant mechanism that regulates HIF-1α stability in the nucleus in response to cellular oxygen levels. This mechanism is based on the collaboration between the SET7/9 methyltransferase and the LSD1 demethylase. SET7/9 adds a methyl group to HIF-1α, which triggers degradation of the protein by the ubiquitin-proteasome system, whereas LSD1 removes the methyl group, leading to stabilization of HIF-1α under hypoxia conditions. In cells from knock-in mice with a mutation preventing HIF-1α methylation (Hif1α^KA/KA), HIF-1α levels were increased in both normoxic and hypoxic conditions. Hif1α^KA/KA knock-in mice displayed increased hematological parameters, such as red blood cell count and hemoglobin concentration. They also displayed pathological phenotypes; retinal and tumor-associated angiogenesis as well as tumor growth were increased in Hif1α^KA/KA knock-in mice. Certain human cancer cells exhibit mutations that cause defects in HIF-1α methylation. In summary, this newly identified methylation-based regulation of HIF-1α stability constitutes another layer of regulation that is independent of previously identified mechanisms.

• Journal of Advanced Marine Engineering and Technology
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• v.40 no.7
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• pp.574-579
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• 2016

Grid systems used in previous studies were determined to be valid only if the length between the perpendiculars in a model ship was in the range of 6-8 m, and the maximum dynamic trim angle was smaller than $1^{\circ}$. The application of the grid system to a small fishing boat can create numerical instability because the dynamic trim of small boats is generally larger than $3^{\circ}$, and their Froude numbers are in the range of 0.3-0.8. In the present study, resistances of a small fishing boat were stably obtained by reducing the length between the center of buoyancy and the inlet boundary of the numerical domain, and by refining grid cells vertically in a region that would be swept by a free surface. The effective power of the small fishing boat was predicted based on the ITTC-1978 two-dimensional analysis. By using the results of previous towing tank tests, the coefficient of quasi-propulsive efficiency and the brake horsepower at a design draft were calculated.

• Journal of the Korean Society for Aeronautical & Space Sciences
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• v.44 no.5
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• pp.381-390
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• 2016

In this study, aeroacoustic characteristics of combined fan are investigated and noise was reduced by applying Serrated Trailing Edge which is known as the method to reduce fan noises. Unsteady CFD (Computational Fluid Dynamics) analysis was carried out using Lattice Boltzmann Method(LBM) to figure out the combined fan's aeroacoustics and experimental results was used to verify simulation results. Results show that different BPFs are generated at the each inner fan and outer fan on the different frequency while Blade Passing Frequency(BPF) of general fans is constant on the entire frequency range. Boundary vortex and vortex shedding are suppressed or dispersed by applying the Serrated Trailing Edge to the inner fan. Furthermore, broadband noise and fan's torque are reduced.

• Journal of the Korean Society of Propulsion Engineers
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• v.10 no.1
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• pp.64-71
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• 2006

For SUAV is required to have the capacity of VTOL and fast forward flight, the SUAV development program has decided to adopt the tiltrotor mechanism which includes helicopter and turboprop mechanisms. From the engine point of view, the key engine parameters such as engine operating mechanism, engine control scheme, the dynamics characteristic of power train, engine intake/exhaust concept, and engine installation requirements should fulfill the requirements of the two different mechanisms, helicopter and turboprop. And for the maximum efficiency of the rotor, rotational speed for the two modes are 20% different, the power train shall find a way to make it so. Meeting these specific requirements for the tiltrotor mechanism, this research begins with a conventional OTS(off-the-shelf) turboshaft engine survey and minimizes engine modification to develop an economical propulsion system. The engine technical review has been performed on the basis of those requirements and capabilities.

• Journal of the Computational Structural Engineering Institute of Korea
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• v.29 no.1
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• pp.37-44
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• 2016

This study is concerned with the numerical investigation of dynamic characteristics of 2.5MW-class wind turbine gearbox in which the misalignment improvement of plenary gear shafts by the flexible pins and the dynamic impact response are analyzed by the finite element method. The tooth contact between gears is modelled using the line element having the equivalent tooth stiffness and the contact ratio to accurately and effectively reflect the load transmission in the internal complex gear system. The equivalent tooth stiffness is calculated by utilizing the tooth deformation analysis and the impulse torque is applied to the input shaft for the dynamics response characteristic analysis. Through the numerical experiments, the equivalent tooth stiffness model was validated and the misalignment improvement of planetary gear shafts was confirmed from the comparison with the cases of fixed shafts at one and both ends.

• Journal of the Korean Society of Propulsion Engineers
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• v.20 no.2
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• pp.75-85
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• 2016

A pyrotechnic system consisting of donor/acceptor pair separated by a gap relies on shock attenuation characteristics of the gap material and shock sensitivity of the donor and acceptor charges. Despite of its common use, numerical study of such pyrotechnic train configuration is seldom reported because proper modeling of the full process requires precise capturing of the shock wave attenuation in the gap prior to triggering a full detonation of high explosive and accurate description of the high strain rate dynamics of the explosively loaded inert confinements. We apply a Eulerian level-set based multimaterial hydrocode with reactive flow models for pentolite donor and heavily aluminized RDX as acceptor charge. The complex shock interaction, critical gap thickness, acoustic impedance, and go/no-go characteristics of the gap test are quantitatively investigated.