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Impact of fetal diagnosis of congenital heart disease on parents (선천성 심질환의 산전 진단이 보호자의 임신 유지 결정에 미치는 영향)

  • Choi, Eun Young;Lee, Chang Hoon;Yoon, Myung Ja;Han, Eun Sook;Hong, Joon Suk;Jung, Yun Sook;Choi, Jung Yun
    • Clinical and Experimental Pediatrics
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    • v.49 no.10
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    • pp.1073-1078
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    • 2006
  • Purpose : This study was performed to assess how a fetal diagnosis of congenital heart disease affects parents, as regards pregnancy management and care of infants after birth. Methods : Database search to find out abnormal fetal echocardiography performed at Seoul National University Children's Hospital from July 1988 to June 2003 revealed 370 examinations. After excluding both arrhythmias without structural cardiac disease and multiple pregnancies, 299 pregnancies remained and this data formed the basis of this analysis. We retrospectively reviewed the medical records with special attention to pregnancy outcomes and also tried to find out factors influencing parental decisions on whether to continue or terminate pregnancy. Results : In this study, the mean gestation age at diagnosis was $28{\pm}6.0weeks$. The mean age of mothers was $30{\pm}3.9$ years old. Younger gestational ages at diagnosis(P=0.000), more severe grades of fetal heart disease(P=0.002) and younger mothers(P=0.014) correlated with terminations of pregnanies. But the grades of fetal status, the grades of associated anomaly, whether in-vitro-fertilization was carried out or not and numbers of previous children were not significant. Conclusion : This study found that the earlier gestational ages at diagnosis, younger maternal age and higher grades of fetal heart disease tended to lead parent to select abortions. Fetal echocardiographies were performed too late. Moreover Koreans have a biased view that malformation is a something incurable and a tragedy not only to oneself, but also to a family. So parents select terminations of pregnancy, even in curable cases. This is very unethical.

Clinical Study of the Correlation of Tumor Necrosis Factor Alpha and the Proteinuria of Henoch-Schönlein Nephritis and Idiopathic Nephrotic Syndrome (Henoch-Schönlein Purpura 신염과 특발성 신증후군에서 Tumor Necrosis Factor Alpha와 단백뇨와의 관련성에 관한 임상적 연구)

  • Jeong, Dong-Ho;Park, Jeong-Hyun;Jeong, Hye-Cheon;Koo, Hyun-Hoe;Lee, Jun-Ho;Ha, Tae-Sun
    • Clinical and Experimental Pediatrics
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    • v.45 no.2
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    • pp.240-246
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    • 2002
  • Purpose : It is not clear that the development of glomerular injury and aggravation by tumor necrosis factor alpha($TNF-{\alpha}$) is related to intrarenal or serum concentration of $TNF-{\alpha}$. So, we studied the relationship between the concentration of $TNF-{\alpha}$ and aggravation of glomerular damage in the Henoch-$Sch{\ddot{o}}nlein$ nephritis(HSN) and idiopathic nephrotic syndrome(INS). Methods : We collected the sera and urines of 21 patients with Henoch-$Sch{\ddot{o}}nlein$ purpura(HSP) and 22 patients with INS visited Chungbuk National University hospital from March 1998 to March 2001. The concentration of $TNF-{\alpha}$ in the sera and urines were measured by sandwich ELISA. Results : Serum $TNF-{\alpha}$ levels in the HSP patients with renal involvement were significantly higher than those without renal involvement(P=0.009). But urine $TNF-{\alpha}$ levels have no correlation with renal involvement(P=0.088). In the HSN patients, proteinuria have a significant correlation with serum $TNF-{\alpha}$ levels(P=0.004) but less correlation with urine $TNF-{\alpha}$ levels(P=0.053). Otherwise, proteinuria have no correlation with serum $TNF-{\alpha}$ levels(P=0.763) but have a significant correlation with urine $TNF-{\alpha}$ levels(P=0.007) in INS. Conclusion : These result suggest that the serum concentration of $TNF-{\alpha}$ would be important to glomerular involvement in HSP. And, it is interesting that proteinuria shows a significant relation with serum $TNF-{\alpha}$ levels in the HSN, but with urine $TNF-{\alpha}$ levels in the INS. This means the major production of $TNF-{\alpha}$ may be originated by extrarenal inflammation in the HSN and by intrarenal tubulo-interstitial damage due to proteinuria in the INS.

Analysis of the Dose Distribution of Moving Organ using a Moving Phantom System (구동팬텀 시스템에 의한 움직이는 장기의 선량분포 분석)

  • Kim, Yon-Lae;Park, Byung-Moon;Bae, Yong-Ki;Kang, Min-Young;Lee, Gui-Won;Bang, Dong-Wan
    • The Journal of Korean Society for Radiation Therapy
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    • v.18 no.2
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    • pp.81-87
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    • 2006
  • Purpose: Few researches have been peformed on the dose distribution of the moving organ for radiotherapy so far. In order to simulate the organ motion caused by respiratory function, multipurpose phantom and moving device was used and dosimetric measurements for dose distribution of the moving organs were conducted in this study. The purpose of our study was to evaluate how dose distributions are changed due to respiratory motion. Materials and Methods: A multipurpose phantom and a moving device were developed for the measurement of the dose distribution of the moving organ due to respiratory function. Acryl chosen design of the phantom was considered the most obvious choice for phantom material. For construction of the phantom, we used acryl and cork with density of $1.14g/cm^3,\;0.32g/cm^3$ respectively. Acryl and cork slab in the phantom were used to simulate the normal organ and lung respectively. The moving phantom system was composed of moving device, moving control system, and acryl and cork phantom. Gafchromic film and EDR2 film were used to measure dose ditrbutions. The moving device system may be driven by two directional step motors and able to perform 2 dimensional movements (x, z axis), but only 1 dimensional movement(z axis) was used for this study. Results: Larger penumbra was shown in the cork phantom than in the acryl phantom. The dose profile and isodose curve of Gafchromic EBT film were not uniform since the film has small optical density responding to the dose. As the organ motion was increased, the blurrings in penumbra, flatness, and symmetry were increased. Most of measurements of dose distrbutions, Gafchromic EBT film has poor flatness and symmetry than EDR2 film, but both penumbra distributions were more or less comparable. Conclusion: The Gafchromic EBT film is more useful as it does not need development and more radiation dose could be exposed than EDR2 film without losing film characteristics. But as response of the optical density of Gafchromic EBT film to dose is low, beam profiles have more fluctuation at Gafchromic EBT. If the multipurpose phantom and moving device are used for treatment Q.A, and its corrections are made, treatment quality should be improved for the moving organs.

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Predicting Migration of a Heavy Metal in a Sandy Soil Using Time Domain Reflectometry (TDR을 이용한 사질토양에서의 중금속 이동 추정)

  • Dong-Ju Kim;Doo-Sung Baek;Min-Soo Park
    • Journal of Korea Soil Environment Society
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    • v.4 no.1
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    • pp.109-118
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    • 1999
  • Recently, transport parameters of conservative solutes such as KCl in a porous medium have been successfully determined using time domain reflectometry (TDR) . This study was initiated to Investigate the applicability of TDR technique to monitoring the fate of a heavy metal ion in a sandy soil and the distribution of its concentration along travel distance with time. A column test was conducted in a laboratory that consists of monitoring both resident and flux concentrations of $ZnCl_2$in a sandy soil under a breakthrough condition. A tracer of $ZnCl_2$(10 g/L) was injected onto the top surface of the sample as pulse type as soon as a steady-state condition was achieved. Time-series measurements of resistance and electrical conductivity were performed at 10 cm and 20 cm of distances from the inlet boundary by horizontal-positioning of parallel TDR metallic rods and using an EC-meter for the effluent exiting the bottom boundary respectively. In addition. Zn ions of the effluent were analyzed by ICP-AES. Since the mode and position of concentration detected by TDR and effluent were different, comparison between ICP analysis and TDR-detected concentration was made by predicting flux concentration using CDE model accommodating a decay constant with the transport parameters obtained from the resident concentrations. The experimental results showed that the resident concentration resulted in earlier and higher peak than the flux concentration obtained by EC-meter, implying the homogeneity of the packed sandy soil. A close agreement was found between the predicted from the transport parameters obtained by TDR and the measured $ZnCl_2$concentration. This indicates that TDR technique can also be applied to monitoring heavy metal concentrations in the soil once that a decay constant is obtained for a given soil.

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Spatial Variability of Soil Moisture Content, Soil Penetration Resistance and Crop Yield on the Leveled Upland in the Reclaimed Highland (고령지 개간지 밭의 토양수분과 경도 및 작물수량의 공간변이성)

  • Park, Chol-Soo;Yang, Su-Chan;Lee, Gye-jun;Lee, Jeong-Tae;Kim, Hak-Min;Park, Sang-Hoo;Kim, Dae-Hoon;Jung, Ah-Yeong;Hwang, Seon-Woong
    • Korean Journal of Soil Science and Fertilizer
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    • v.39 no.3
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    • pp.123-135
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    • 2006
  • Spatial variability and distribution map of soil properties and the relationships between soil properties and crop yields are not well characterized in agroecosystems that have been land leveled to facilitate more cultivation of the new reclaimed sloping highland. Potato, onion, carrot, Chinese cabbage and radish were grown on the coarse sandy loam soil in 2004. Soil moisture content, soil penetration resistance and crop yield were sampled in the $10m{\times}50m$ field consisted of five plots. Sampling sites of each cultivation plot were 33 for the soil moisture, 11 for the soil penetration and 33 for the crop yield. The results of semivariance analysis, most of models were shown spherical equation. The significant ranges of each spatial variability model for the soil moisture, soil penetration and crop yield were broad as 33-35 meters in the potato cultivation plot, and that in the Chinese cabbage cultivation plot was narrow as 5-6 meters. The coefficient of variances (C.V.) of moisture, penetration and yield were various from 14 to 59 percents in five cultivation plots. The highest C.V. of potato yield was 59 percents, and that of the radish cultivation plot was as low as 14 percents. The required sample numbers for the determination of soil moisture content, soil penetration resistance and crop yield with error 10% at 0.05 significant level were ranged 8-40 for soil moisture, 7-25 for soil penetration and 424-4,678 for crop yield. The variogram and distribution map by kriging described field characteristics well so that the spatial variability would be useful for soil management for better efficiency and precision agriculture in the reclaimed highland.

A Brief Report of the Short-Term Home Range Study of a Pair of Raccoon Dogs(Nyctereutes procyonoides koreensis) in a Rural Area of Gurye, Chonnam Province, South Korea Using Radiotracking Method (전라남도 구례 농촌지역에서의 단기원격무선추적을 이용한 너구리(Nyctereutes procyonoides koreensis) 한 쌍의 행동권에 관한 연구)

  • Kim, Baek-Jun;Choi, Tae-Young;Park, Chong-Hwa;Kim, Young-Jun;Lee, Hang
    • Korean Journal of Environment and Ecology
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    • v.22 no.3
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    • pp.230-240
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    • 2008
  • The primary aim of this study is to estimate the home range of a pair of raccoon dogs(Nyctereutes procyonoides koreensis) and to compare with the previous study of raccoon dogs in a rural area of Gurye, the southern part of South Korea. Radiotracking was regularly carried out on 2 raccoon dogs for 2 days every 2 months(in June, August, October and December, 2006). During the 2 days, radiotracking was usually conducted every $1{\sim}3$ hours through day and night. The analysis of tracking data with a total of $46{\sim}64$ bearings showed that the total home range size of the pair was $0.41km^2$, and mean home range size was $0.32km^2$ by 95% minimum convex polygons(MCP) estimate. The home ranges of the male and female were largely overlapping(about $70{\sim}95%$), and the sizes were not very much different from each other. However, there was a big difference between day $(0.01km^2)$ and night-time $(0.35km^2)$ home ranges, and it was largest in summer$(0.56km^2)$ and smallest in winter $(<0.01km^2)$. In addition, the home range of the pair included 1 core area and 4 different feeding areas. In conclusion, our raccoon dog home range data using the same individuals but with more frequent bearings per day and more extended tracking intervals still showed very similar results to the previous study with less frequent bearings per day and more extensive tracking days.

A Methodology of Ship Detection Using High-Resolution Satellite Optical Image (고해상도 광학 인공위성 영상을 활용한 선박탐지 방법)

  • Park, Jae-Jin;Oh, Sangwoo;Park, Kyung-Ae;Lee, Min-Sun;Jang, Jae-Cheol;Lee, Moonjin
    • Journal of the Korean earth science society
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    • v.39 no.3
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    • pp.241-249
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    • 2018
  • As the international trade increases, vessel traffics around the Korean Peninsula are also increasing. Maritime accidents hence take place more frequently in the southern coast of Korea where many big and small ports are located. Accidents involving ship collision and sinking result in a substantial human and material damage as well as the marine environmental pollution. Therefore, it is necessary to locate the ships quickly when such accidents occur. In this study, we suggest a new ship detection index by comparing and analyzing the reflectivity of each channel of the Korea MultiPurpose SATellite-2 (KOMPSAT-2) images of the area around the Gwangyang Bay. A threshold value of 0.1 is set based on a histogram analysis, and all vessels are detected when compared with RGB composite images. After selecting a relatively large ship as a representative sample, the distribution of spatial reflectivity around the ship is studied. Uniform shadows are detected on the northwest side of the vessel. This indicates that the sun is in the southeast, the azimuth of the actual satellite image is $144.80^{\circ}$, and the azimuth angle of the sun can be estimated using the shadow position. The reflectivity of the shadows is 0.005 lower than the surrounding sea and ship. The shadow height varies with the position of the bow and the stern, perhaps due to the relative heights of the ship deck and the structure. The results of this study can help search technology for missing vessels using optical satellite images in the event of a marine accident around the Korean Peninsula.

Quality Characteristics and Consumer Perception of Dacquoise with Rice Bran Dietary Fiber (현미 식이섬유를 대체한 다쿠아즈의 품질 특성 및 소비자 기호도)

  • Yeom, Kyung Hun;Bing, Dong Joo;Kim, Sung Hyun;Choi, Kap Seong;Chun, Soon Sil
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.46 no.1
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    • pp.92-99
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    • 2017
  • People have become more interested in fiber intake due to the rise of noncommunicable diseases such as hyperlipemia and abdominal obesity. This study was carried out to develop dacquoise incorporating different amounts of rice bran dietary fiber (5%, 10%, 15%, and 20%). Dacquoise characteristics such as viscosity, specific volume, moisture content, color, and texture were measured. Consumer acceptance and check-all-that-apply on characteristics of dacquoise with rice bran dietary fiber were observed. Increasing amounts of rice bran dietary fiber resulted in increasing viscosity of batter as well as higher specific volume, lightness, and hardness of finished product. On the contrary, yellowness and redness of dacquoise increased as the amount of rice bran dietary fiber increased. While there was no effect of rice bran dietary fiber on moisture content (range of 26.53~25.35%). According to the consumer acceptance test, dacquoise with 5% of rice bran dietary fiber showed the highest liking score in color and overall acceptance (5.9 and 5, respectively). The findings from the principle component analysis of principle component (PC) 1 (71.04% explanation) showed that as rice bran dietary fiber increased, texture of the product got drier, and consumers described the product with 20% rice bran dietary fiber as cotton mouth and 5% rice bran dietary fiber as sticky. PC2 (16.54% explanation) demonstrated 5% and 10% rice bran dietary fiber, and dacquoise had nutty and soybean notes while 15% and 20% rice bran dietary fiber dacquoise had flour, bitter, and salty flavors. Based on these results, the optimum addition level of rice bran dietary fiber for dacquoise is 5%.

A study on the mandibular setback osteotomy and reduction genioplasty in mandibular prognathism with long anterior facial height (과도한 하안면 고경을 동반하는 하악전돌증환자의 하악골 후퇴술과 이부 감소 성형술식에 관한 연구)

  • Chang, Young-Il;Im, Dong-Hyuk;Suhr, Jeong-Hoon;Kim, Tae-Woo
    • The korean journal of orthodontics
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    • v.30 no.3 s.80
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    • pp.343-355
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    • 2000
  • The purpose of this study was to evaluate the amount and interrelationship of hard and soft tissue changes after mandibular setback osteotomy and reduction genioplasty in mandibular prognathism with long anterior facial height. The control group (Group A) consisted of 20 patients who had severe horizontal discrepancy. They experienced Presurgical orthodontic treatment and orthognathic surgery via mandibular setback. The experimental group (Group B) consisted of 20 patients who had severe horizontal and vertical discrepancy. They experienced presurgical orthodontic treatment and orthognathic surgery via mandibular setback and reduction genioplasty. The presurgical and postsurgical lateral cephalograms were evaluated. The computerized statistical analysis was tarried on with EXCEL 97 program. The results were as follows : 1. The correlation of hard and soft tissue horizontal changes in lower 2/3 of lower anterior facial height were high for both groups. The correlation coefficients of hard tissue changes and Ls, Stm, Li changes in Group B were moderately higher than Group A. 2. The correlation of hard and soft tissue vortical changes in Group B were lower than Group A. (except for pointB-Ils, Me-Me') 3. The ratio for soft tissue to Pog in Group B was lower than Group A. The ratios of hard and soft tissue vertical changes were 32% at Ils, 54% at Pog', and 60% at Me'. 4. The ratio of lower anterior facial height to total anterior facial height was reduced for both groups. But ratio of upper 1/3 of lower anterior facial height to total anterior facial height did not changed significantly in Group B. 5. Reduction genioplasty combined with mandibular setback procedure showed no change in upper one third(Sn-Stm) and significant decrease(Stm-Me') in the lower two thirds of the soft-tissue anterior lower facial height

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Analysis of Household Textbooks for MiddleㆍHigh School in Colonial Age (식민지 시대 '가사교과서'에 관한 연구: 1930년대를 중심으로)

  • Jun Mi-Kyung
    • Journal of Korean Home Economics Education Association
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    • v.16 no.3
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    • pp.1-25
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    • 2004
  • This study analyzes the external forms of the household textbooks and also the contents of them used at girls' middleㆍhigh schools during the period of Japanese ruling over Korea. To this end, 8 household textbooks published from 1928 to 1937 were analyzed. The results of the study are summarized as follows. 1. The household subject had become the one of the most important subjects to girl students as the practical uses were emphasized in educational area during the period. As a result. the classes of the household were the second in hours, following the class of Japanese (the national language) to girl students. 2. The contents of the household textbooks were intended to contain 'the modern' and 'the newest'. The students were also suggested to apply the contents of the textbooks to real home life. Many pictures, photos and illustrations were included in household textbooks to help students to understand the contents of the subject. 3. The purposes of the household class were the reformation of the living conditions and home economics. 4. The external characteristics of the household textbooks during the period were as follows. - Written in Japanese vertically and the size of the textbook was A5 (150/210) with pulp paper of good quality - The type style of the body of the textbooks was Ming-style type- The sequent order of the textbooks was the outer cover, the title page, pictorial, introduction, table of contents, the body, appendix and the back cover. 5. The household textbooks consisted of the first volume and the second volume. The first volume contained clothing and textiles, food and nutrition and housing. Taking care of the aged. nursing. child care, household economy and home management were included in the second volume. 6. The household textbooks were designed to make women the housewives.

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