• Journal of the Earthquake Engineering Society of Korea
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• v.13 no.1
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• pp.27-34
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• 2009

Site amplification should be considered in order to estimate Soil-Structure Interaction (SSI), seismic source and attenuation parameters with a greater degree of reliability. The horizontal to vertical (H/V) ratio technique, originally proposed by Nakamura (1989), has been applied to analyze the surface waves in microtremor records. Recently, its application has been extended to the shear wave energy of strong motion in order to study the site transfer function. The purpose of this paper is to estimate the H/V spectral ratio using the observed data from 9 seismic stations distributed within the Southern Korean Peninsula, from the Odesan earthquake (2007/01/20). The results show that most of the stations have more stable amplification characteristics in a low frequency band than in a high frequency band. However, each seismic station showed its own characteristic resonant frequency and low and high frequency. The resonant frequency at each station should be estimated carefully, because the quality of seismic data is dependent on the resonant frequency. It can be obtained more reliable results of seismic source and attenuation parameters, if seismic ground motions which deconvolved from site transfer function is used. The site amplification data from this study can be used to generally classify the sites within the Southern Korean Peninsula.

• ETRI Journal
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• v.24 no.2
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• pp.81-96
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• 2002

This paper describes our design of a hybrid amplifier composed of a distributed Raman amplifier and erbium-doped fiber amplifiers for C- and L-bands. We characterize the distributed Raman amplifier by numerical simulation based on the experimentally measured Raman gain coefficient of an ordinary single mode fiber transmission line. In single channel amplification, the crosstalk caused by double Rayleigh scattering was independent of signal input power and simply given as a function of the Raman gain. The double Rayleigh scattering induced power penalty was less than 0.1 dB after 1000 km if the on-off Raman gain was below 21 dB. For multiple channel amplification, using commercially available pump laser diodes and fiber components, we determined and optimized the conditions of three-wavelength Raman pumping for an amplification bandwidth of 32 nm for C-band and 34 nm for L-band. After analyzing the conventional erbium-doped fiber amplifier analysis in C-band, we estimated the performance of the hybrid amplifier for long haul optical transmission. Compared with erbium-doped fiber amplifiers, the optical signal-to-noise ratio was calculated to be higher by more than 3 dB in the optical link using the designed hybrid amplifier.

• Geomechanics and Engineering
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• v.4 no.1
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• pp.1-18
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• 2012

The spatial variation of ground motion in Kolkata Metropolitan District (KMD) has been estimated by generating synthetic ground motion considering the point source model coupled with site response analysis. The most vulnerable source was identified from regional seismotectonic map for an area of about 350 km radius around Kolkata. The rock level acceleration time histories at 121 borehole locations in Kolkata for the vulnerable source, Eocene Hinge Zone, due to maximum credible earthquake (MCE) moment magnitude 6.2 were generated by synthetic ground motion model. Soil investigation data of 121 boreholes were collected from the report of Soil Data Bank Project, Jadavpur University, Kolkata. Surface level ground motion parameters were determined using SHAKE2000 software. The results are presented in the form of peak ground acceleration (PGA) at rock level and ground surface, amplification factor, and the response spectra at the ground surface for frequency 1.5 Hz, 3 Hz, 5 Hz and 10 Hz and 5% damping ratio. Site response study shows higher PGA in comparison with rock level acceleration. Maximum amplification in some portion in KMD area is found to be as high as 3.0 times compared to rock level.

• Korean Journal of Animal Reproduction
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• v.20 no.2
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• pp.89-99
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• 1996

The purpose of this study was to develop the diagnosis techniques for sex determination of rabbit embryos at preimplantation stage. To detect male specific sequences using polymerase chain reaction, two genes functional on sex determination including SRY and ZFX/Y genes were targeted using multiple oligonucleotide primer sets. Three of them for conserved SRY gene were used for appropriate amplification pattern, and then only one primer set #3 proved to be most efficient, showing male-specific strong signal ofamplified sequences. Using this male specific bandsfrom human, cattle, pig and mouse, the gender of rabbit was determined. As an another system for sex determination system, amplified 910bp fragment from ZFX/Y was digested with several restriction endonuclease and showed gender specific restriction fragments only by Hinf I. Using two different system for sex identification of rabbit in this study, blind tests for 17 samples was conducted and showed identical results from two different methods. And then, amplification limit of PCR reaction for template DNA was estimated using various amounts of DNA for both SRY and ZFX/Y systems, resulted as 20pg and 800pg, respectively. With this results, test for gender identification of rabbit embryos were performed using SRY derived amplification system. From total 22 embryos selected for its developmental state 18 were identified as male embryos, showing significant difference from expected sex ratio 1:1. This biased sex ratio was interpreted as to have been caused by the fact, reported by the fact, reported by several researchers, that male embryos develop more rapidly and are more resistant against the in vitro manipulation than female embryos.

• The Journal of the Acoustical Society of Korea
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• v.36 no.4
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• pp.238-246
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• 2017

High frequency ultrasound imaging typically suffers from low sensitivity due to the small aperture of high frequency transducers and shallow imaging depth due to the frequency-dependent attenuation of ultrasound. These limitations should be overcome to obtain high-frequency, high- resolution ultrasound images. One practical solution to the problems is a high-performance signal receiver capable of detecting a very small signal and amplifying the signal with minimal electronic noise addition. This paper reports a recently developed low-noise, wideband ultrasound receiver for high-frequency, high-resolution ultrasound imaging. The developed receiver has an amplification gain of up to 73 dB and a variable amplification gain range of 48 dB over an operating frequency of 80 MHz. Also, it has an amplification gain flatness of ${\pm}1dB$. Due to these high performances, the developed receiver has a signal-to-noise ratio of at least 8.4 dB and a contrast-to-noise ratio of at least 3.7 dB higher than commercial receivers.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• v.26 no.4
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• pp.355-362
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• 2000

Neoplastic growth is characterized by alterations of oncogenes and antioncogenes. The interaction between activated oncogenes and functional deletion of antioncogene appears to be the driving force directing normal cells to uncontrolled growth resulting in tumor. In addition to those genes mentioned, other genes controlling the entry of cells into the cell cycle have recently been implicated in cancer development. The overexpression of the cyclin D1 gene, which has been mapped to 11q13, either by gene rearrangement or amplification has been noted in various malignant tumors. The product of the cyclin D1 gene forms a complex with cyclin-dependent protein kinases(CDK4) that governs a key transition in the cell cycle. The relationships between the overexpression of cyclin D1 assessed by immunihistochemistry and the amplification of the cyclin D1 gene by differential polymerase chain reaction(DPCR) using primers for dopamin D2 receptor gene in 13 cases of squamous cell carcinomas of the oral cavity have been studied. The semiquantitative assay of cyclin D1 amplification has been made by cyclin D1/dopamin D2 receptor(CD/DR) ratio. The results were as follows; 1. In the normal tissue and the tumor, the CD/DR ratios were 0.82 and 1.36 respectively. This implicates 1.65-fold amplification of cyclin D1 gene in tumor compared to that in normal tissue. 2. The tumor tissue which showed overexpression of cyclin D1 by immunohistochemistry revealed 2-fold amplification of cyclin D1 compared to the normal tissue. 3. The tumor tissue which showed mild expression of cyclin D1 by immunihistochemistry revealed 1.7-fold amplification of cyclin D compared to the normal tissue. 4. The cyclin D1 was overexpressed in the tumor tissue at the rate of 38%. Above results suggest that cyclin D1 has close correlation with the development of carcinoma in the oral cavity. But further studies were needed to elucidate the carcinogeneic mechanisms by comparative studies among cyclin D1, pRb and p53.

• Tunnel and Underground Space
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• v.19 no.5
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• pp.432-439
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• 2009

For more reliable estimation of seismic source, attenuation properties and dynamic ground property, site amplification function should be considered. Among various estimation methods, this study used the Nakamura's method (1989) for estimating site amplification characteristics. This method was originally applied to the surface waves of background noise and therefore there are some limitations in applying to general wave energy. However, recently this method has been extended and applied to the S wave energy successfully. This study applied the method to S wave and Coda wave energy, which is equivalent to the backscattered S wave energy. We used more than 60 observed ground motions from 5 earthquakes which were occurred recently, with magnitude range from 3.6 to 5.1. Each station showed characteristic site amplification property in low-, high- and resonance frequencies. Some of the stations showed as high as 4 times of site amplification in the range of specific frequencies, which may imply abnormal small scale geologic strata below the station or development of various trapped modes in the basin structure. Moreover, removal of site amplification can give us more reliable seismic source and attenuation parameters, addition to the seismic hazard estimation.

• Proceedings of the Korean Society for Noise and Vibration Engineering Conference
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• 2007.11a
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• pp.1325-1328
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• 2007

When we visualize the sound field radiated from a spherical sound source, spherical acoustic holography is proper among acoustic holography methods. However, there are measurement errors due to sensor position mismatch, sensor mismatch, directivity of sensor, and background noise. These errors are amplified if one predicts the pressures close to the sources: backward prediction. The goal of this paper is to quantitatively examine the effects of the error due to sensor position mismatch on acoustic pressure estimation. This paper deals with the cases of which the measurement deviations are distributed irregularly on the hologram plane. In such cases, one can assume that the measurement is a sample of many measurement events, and the cause of the measurement error is white noise on the hologram plane. Then the bias and random error are derived mathematically. In the results, it is found that the random error is important in the backward prediction. The relationship between the random error amplification ratio and the measurement parameters is derived quantitatively in terms of their energies.

• Journal of the Korean Society for Precision Engineering
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• v.24 no.12
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• pp.88-94
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• 2007

A flexure hinge-based compliant stage driven by stack-type piezoelectric elements has high precision motion but small operational range due to the characteristics of the piezoelectric element. Since the common flexure hinges can be broken by excessive deflection when the displacement is amplified by a high amplification ratio, a flexure hinge mechanism for large deflection is required. A cartwheel-type flexure hinge has an advantage of larger deflection compared with the common flexure hinges. This study presents a rotation stage with cartwheel-type flexure hinges driven by a stack-type piezoelectric element. The characteristics and the performance of the rotation stage are described by the terms of principal resonance frequency, amplification ratio of rotational displacement, maximum rotational displacement and block moment, in which the terms are analyzed by geometric parameters of the rotation stage. The analyzed results will be used as the guideline of the design of the rotation stage.

• Journal of Life Science
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• v.9 no.1
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• pp.14-16
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• 1999

Genetic variability was monitored by random amplified polymorphic DNA-polymerase chain reaction (RAPD-PCR) in dicofol-susceptible (S), dicofol-resistant (R) and its reverse-selected (RS) strains of two-spotted spider mite, of Tetranychus urticae. Before the reverse-selection, RS strain, selected reversely from R strain, was 23-fold resistance ratio at {TEX}$LC_{50}${/TEX} to S strain. The resistance was started to in incline slowly to the resistance level of S strain after one year, and the resistance ratio was 4-fold in the 7 years after then. PCR-amplification of T. urticae DNA showed polymorphism in the amplifications with 12 primers in 100 kinds of arbitrary DNA sequences. RAPD amplification with primer OPR-12 (5`-ACAGGTGCGT-3`) showed amplified bands at 1,000 base pair in the S-and RS-strain, and at 350 base pair in R-strain. The results of polymorphism are genetic variabilities derived from development and selection of resistance in each strain. The peculiarly amplified fragments were guessed to participate in dicofol resistance. From the analysis of genetic similarity, it is inferred the gene composition of S-and RS-strain is much closer than that of R-strain.