• Title/Summary/Keyword: aluminum activity

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The Protective Effect of Rosmarinic Acid on the Aluminum of Dementia Inducer (치매유발제인 알루미늄에 대한 Rosmarinic Acid의 보호 효과)

  • Jung, In-Ju;Seo, Young-Mi;Jekal, Seung-Joo
    • Korean Journal of Clinical Laboratory Science
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    • v.49 no.1
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    • pp.8-14
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    • 2017
  • To examine the protective effect of rosmarinic acid on the aluminum of dementia inducer, cultured C6 glioma cells were treated with various concentrations of aluminum chloride ($AlCl_3$) or rosmarinic acid. The cell viability, electron donating ability (EDA), superoxide dismutase (SOD)-like activity, and inhibitory activity of lipid peroxidation were evaluated for the antioxidant effect of rosmarinic acid. In these cultures, $AlCl_3$ sowed a cytotoxic effect by decreasing the cell viability in a dose-dependent manner; then, the $XTT_{50}$ value was measured at $142.2{\mu}M$ of $AlCl_3$ after treating the cultured C6 glioma cells with media containing $120{\sim}160{\mu}M\;AlCl_3$. Therefore, its toxicity was determined as mid-cytotoxic by Borenfreund and Puerner's toxic criteria; while, vitamin E of antioxidant markedly increased the cell viability on $AlCl_3$-induced cytotoxicity in these cultures. This study showed the antioxidant effect of rosmarinic acid via several assays, such as electron donating activity (EDA), superoxide dismutase (SOD)-like activity, and inhibitory activity of lipid peroxidation. From these findings, it is suggested that the oxidative stress is involved in $AlCl_3$-induced cytotoxicity, and rosmarinic acid was effective in the protection of $AlCl_3$-induced cytotoxicity by antioxidant activity. In conclusion, natural resources, like rosmarinic acid, may be a putative antioxidant agent for the treatment of reactive oxygen species (ROS)-mediated disease, such as dementia.

The Effect of Seawater Temperature on the Electrochemical Corrosion Behaviour of Stainless Steels and Anodized Aluminum Alloys (스테인리스강과 양극산화된 알루미늄 합금의 전기화학적 부식특성에 미치는 해수온도의 영향)

  • Chong, Sang-Ok;Kim, Seong-Jong
    • Corrosion Science and Technology
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    • v.20 no.2
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    • pp.85-93
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    • 2021
  • The corrosion damage of materials in marine environment mainly occurs by Cl- ions due to the breakdown of passive films. Additionally, various characteristics in seawater such as salinity, temperature, immersion time, flow rate, and biological activity also affect corrosion characteristics. In this study, the corrosion characteristics of stainless steels (STS 304 and STS 316L) and anodized aluminum alloys (AA 3003 and AA 6063) were evaluated with seawater temperature parameters. A potentiodynamic polarization experiment was conducted in a potential range of -0.25 V to 2.0 V at open circuit potential (OCP). Corrosion current density and corrosion potential were obtained through the Tafel extrapolation method to analyze changes in corrosion rate due to temperature. Corrosion behavior was evaluated by measuring weight loss before/after the experiment and also observing surface morphology through a scanning electronic microscope (SEM) and 3D microscopy. Weight loss, maximum damage depth and pitting damage increased as seawater temperature increased, and furthermore, the tendency of higher corrosion current density with an increase of temperature attributed to an increase in corrosion rate. There was lower pitting damage and lower corrosion current density for anodized aluminum alloys than for stainless steels as the temperature increased.

Effects of Green Tea Activities in Rats with Administration of Aluminum in Drinking Green Tea (녹차 음용이 알루미늄을 투여한 흰쥐의 혈청 효소 활성도에 미치는 영향)

  • 신미경;한성희;한경조
    • Journal of the East Asian Society of Dietary Life
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    • v.6 no.2
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    • pp.127-134
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    • 1996
  • This study was performed to investigate the effects of green tea activites in rats with administration of aluminum in drinking green tea. Male Sprague-Daweley rats were divided into five groups consisting of the control, aqueous green tea at the level of 1.5%, a aquous green tea(1.5%) and aluminum sulfate solution 500ppm, before the 2 weeks administration by aquous green tea(1.5%) and after the 2 weeks aluminum sulfate solution 500ppm, aluminum sulfate solution 500ppm. After 4weeks of feeding, serum enzymes activites were measured for experimental rats, and analyzed the activites of alanine amino trans aminase(ALT), asparate amino transminase(AST) , lactate dehydrogenase(LDH), cholinesterase(ChE). Comparing to control group, Alanine amino trans aminase (ALT) was decreased in aqueous green tea administrated group and increased significantly administration by aluminum sulfate solution 500ppm group. Alanine amino trans aminase(ALT) was decreased administration by aqueous green tea group and Increased addition to aluminum sulfate solution 500ppm group as compared to control group. Lactate dehydrogenase(LDH) was increased compared to control group by experimental group and increased significantly administration by aluminum sulfate solution 500ppm. Cholinesterase (ChE) activity was decreased compared to control group by experimental group.

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Analysis of the Formation of Rear Contact for Monocrystalline Silicon Solar Cells (단결정 실리콘 태양전지의 후면 전극형성에 관한 비교분석)

  • Kwon, Hyuk-Yong;Lee, Jae-Doo;Kim, Min-Jeong;Lee, Soo-Hong
    • Journal of the Korean Institute of Electrical and Electronic Material Engineers
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    • v.23 no.7
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    • pp.571-574
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    • 2010
  • Surface recombination loss should be reduced for high efficiency of solar cells. To reduce this loss, the BSF (back surface field) is used. The BSF on the back of the p-type wafer forms a p+layer, which prevents the activity of electrons of the p-area for the rear recombination. As a result, the leakage current is reduced and the rear-contact has a good Ohmic contact. Therefore, the open-circuit-voltage (Voc) and fill factor (FF) of solar cells are increased. This paper investigates the formation of the rear contact process by comparing aluminum-paste (Al-paste) with pure aluminum-metal(99.9%). Under the vacuum evaporation process, pure aluminum-metal(99.9%) provides high conductivity and low contact resistance of $4.2\;m{\Omega}cm$, but It is difficult to apply the standard industrial process to it because high vacuum is needed, and it's more expensive than the commercial equipment. On the other hand, using the Al-paste process by screen printing is simple for the formation of metal contact, and it is possible to produce the standard industrial process. However, Al-paste used in screen printing is lower than the conductivity of pure aluminum-metal(99.9) because of its mass glass frit. In this study, contact resistances were measured by a 4-point probe. The contact resistance of pure aluminum-metal was $4.2\;m{\Omega}cm$ and that of Al-paste was $35.69\;m{\Omega}cm$. Then the rear contact was analyzed by scanning electron microscope (SEM).

Determination of Trace Impurities in High Purity Aluminum by Instrumental Neutron Activation Analysis (고순도알루미늄의 비파괴 중성자방사화분석)

  • Cho, Seung-Yeon;Kim, Young-Kuk;Chung, Yong-Sam
    • Nuclear Engineering and Technology
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    • v.24 no.2
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    • pp.163-167
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    • 1992
  • Nondestructive neutron activation analysis of copper in high purity Aluminum samples which can be used as a parameter of impurity is investigated and determined. Other 23 trace impurity elements in the samples are also determined. In the analysis of copper, the new irradiation method using thermal column was applied to reduce the interfering activity of 24Na produced by 27Al(n,$\alpha$)24Na reaction induced by fast neutron. As a result, the interference can be reduced to 100 times more than other activation methods. Also the influence by activity of 24Na is found in the range of 2~3 %. It has been observed that the copper contents in so-ratted“six nine”class standard aluminum samples are about 0.54 $\pm$ 0.08 ppm. By the comparison with other values re-ported, our results are reasonable and can be available as a improved routine analysis.

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Immunogenicity of a Gamma-irradiat d Brucella Vaccine (Gamma선 조사로 만든 Brucella Vaccine의 생쥐에 대한 면역력)

  • Ahn, Tai-Hew
    • The Journal of the Korean Society for Microbiology
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    • v.6 no.1
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    • pp.15-20
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    • 1971
  • A vaccine was prepared by $10^6$ r cobalt-60 irradiation of lyophilized virulent Brucella melitensis and tested in mice for immunogenic activity against a lethal challenge dose of the homologous strain. The vaccine(GIV) produced a high degree of immunity in mice, and comparative studies demonstrated it to be superior to vaccines prepared by heat or by chemical(ether, formalin, or phenol) treatment. Living vaccines, Brucella abortus. strain 19 and an R-form of Brucella melitensis were lethal for mice in larger doses. A comparison of seven adjuvant mixtures for use with the GIV showed no statistically significant difference, but. Freund's complete adjuvant and a mixture of aluminum-potassium sulfate and pectin appeared to enhance the activity of the GIV.

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Fatigue Assessment Using SPR and Adhesive on Dissimilar Materials (SPR 과 접착제를 이용한 이종재료 접합의 피로평가)

  • Kim, Tae-Hyun;Suh, Jeong;Kang, Hee-Shin;Lee, Young-Shin;Park, Chun-Dal
    • Journal of the Korean Society for Precision Engineering
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    • v.28 no.10
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    • pp.1204-1209
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    • 2011
  • In this study, fatigue life is evaluated by comparing with lighter car body through the experiment on SPR joints. An experimental activity on sheet metal samples of Aluminum 5J32 and Steel SPRC440 has been conducted to achieve better understanding of the process. In addition, SPR joint used less than the existing Spot Welding improves joint strength and fatigue life is evaluated by using SPR and adhesive joining Hybrid. Joining(bonding) strength and fatigue life on SPR and Hybrid (SPR + adhesive) are evaluated throughout the experiment. With joining strength than 20 % of the aluminum material, dissimilar materials has improved over 2 times as large as the strength In case of dissimilar materials, the fatigue life of aluminum is increased by 1.6 to 2.5 times as large as the life.

The Effect of Zr Addition on AM50 Mg Alloys Foam Metals (AM50 Mg합금 발포금속의 제조와 지르코늄 첨가 영향)

  • Kim, Byeong-Gu;Tak, Byeong-Su;Hur, Bo-Young
    • Journal of Korea Foundry Society
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    • v.30 no.6
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    • pp.217-223
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    • 2010
  • Foamed metal has become an attractive material, which has unique physical, thermal, acoustic, damping and mechanical properties, because large amount of pores are distributed in the metal matrix. Therefore, metal foam can be used for the light weight application in automotive, locomotive, aerospace fields. Aluminum foams have been developed successfully and will be employed in the next generation of energy absorption boxes. Magnesium alloys are most eligible candidate to substitute aluminum alloy, especially for lower density and higher damping properties in wide industrial fields. Magnesium alloy foams are expected to be particularly advantageous due to two thirds the density of aluminum. However, foaming magnesium have been weakness of high activity, difficult processing and very dangerous. In order to upgrade this problem, AM50 magnesium alloy which has better characteristic is safe to use through foaming time and alloying element in this study.

The Protective Effect of Lonicerae flos Extract on Cultured C6 Glioma Cells Damaged by Aluminum of Dementia Inducer (치매유발제인 알루미늄으로 손상된 배양 C6 Glioma 세포에 대한 금은화 추출물의 보호 효과)

  • Jung, Jai-Yun;Jung, In-Ju;Jekal, Seung-Joo
    • Korean Journal of Clinical Laboratory Science
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    • v.49 no.3
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    • pp.271-278
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    • 2017
  • This study was performed to evaluate the cytotoxicity of aluminum chloride ($AlCl_3$), and the protective effect of Lonicerae flos (LF) extract on $AlCl_3-induced$ cytotoxicity in the cultured C6 glioma cells. Here, the cell viability and antioxidative effects, such as DPPH-radical scavenging activity, superoxide anion scavenging activity, and lipid peroxidation (LP), were assessed. $AlCl_3$ significantly decreased the cell viability in a dose-dependent manner; the $XTT_{50}$ value was measured at $128.8{\mu}M$ of $AlCl_3$. The cytotoxicity of $AlCl_3$ was determined as highly toxic the y Borenfreund and Puerner's toxic criteria. The butylated hydroxytoluene (BHT) and antioxidant both significantly increased the cell viability, which was damaged by $AlCl_3-induced$ cytotoxicity in these cultures. In the protective effect of LF extract on $AlCl_3-induced$ cytotoxicity, the LF extract significantly increased the superoxide anion scavenging activity and inhibitory activity of LP, as well as the DPPH-radical scavenging activity. From these results, it is suggested that the oxidative stress may have been involved in the cytotoxicity of $AlCl_3$, and LP extract effectively protected $AlCl_3-induced$ cytotoxicity through the antioxidative effects. Conclusively, the natural resources, like LP extract, may be a putative therapeutic agent for the treatment of dementia induced by allergen like aluminum correlated with the oxidative stress.

A study on the total cell count variation of commercial liquid seed by adding PAC and PAS (PAC 및 PAS 첨가에 따른 상업용 액상 종균제의 총균수 변화에 관한 연구)

  • 박미자;박경식;김승재
    • Journal of environmental and Sanitary engineering
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    • v.16 no.2
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    • pp.79-90
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    • 2001
  • Commercial liquid seeds are used for supplying active microbial flora to organic wastewater treatment plants of high feed-to-microorganism ratio and to maintain optimal microbial condition during unsteady state operation of the biological wastewater treatment plant. In addition to bacterial cells, the liquid weeds contain various additives for special purposes as well as organic substrates for energy supply. The additives give physical stability for the maintenance of microbial decomposition activity and ability to control the overgrowth of seed strains. In this work, the effects of addition of two kinds of typical substrate additives, poly aluminum chloride(PAC) and poly aluminum sulfate(PAS) on the consitutional total cell counts(CFU/ml) of four kinds of reorganization liquid seeds(RLS I, RLS II, RLS III and RLS IV) were studied experimentally. The addition of PAC and PAS gave negative effect on TCC constitution for the four seeds studied.

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