• International Journal of Stem Cells
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• 제17권2호
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• pp.182-193
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• 2024

To address the limitations of animal testing, scientific research is increasingly focused on developing alternative testing methods. These alternative tests utilize cells or tissues derived from animals or humans for in vitro testing, as well as artificial tissues and organoids. In western countries, animal testing for cosmetics has been banned, leading to the adoption of artificial skin for toxicity evaluation, such as skin corrosion and irritation assessments. Standard guidelines for skin organoid technology becomes necessary to ensure consistent data and evaluation in replacing animal testing with in vitro methods. These guidelines encompass aspects such as cell sourcing, culture techniques, quality requirements and assessment, storage and preservation, and organoid-based assays.

• Journal of the Korea Society for Simulation
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• 제10권1호
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• pp.51-62
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• 2001

For the productivity improvement, it is necessary to analyze problem of the system and evaluate alternative plans. But, it if hard to experiment and evaluate alternative plans in real existing system. Therefore, it is necessary to synthetically analyze and evaluate alternative plans using simulation and statistical analysis method. In this case study, as a simulation language, Promodel is used to compare and evaluate four alternatives which are considered to improve the productivity of an object system. The object system is constituted of a pretreatment line and a painting line. The purpose of this study is to analyze whether the decrease of the down time in pretreatment line can be effective to the productivity improve comparing with exiting system and other alternatives. The other purpose is to choose an alternative that has the best productivity improvement. The results of the simulation show that the possibility of improvement in productivity by decreasing the down time of pretreatment line. Two-Stage Bonferroni Procedure is used to choose the best alternative.

• Journal of Korea Society of Industrial Information Systems
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• 제13권5호
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• pp.124-132
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• 2008

Most companies in Korea that are implementing six sigma programs evaluate belt's project performance based on their own evaluation systems. Financial performance is a major criterion to evaluate project performance. New project evaluation systems which are based on not only financial performance but also non-financial performance need to be presented for better performance system. The study presents the integration system of balanced scorecard and six sigma project evaluation systems to show balanced view points of performance. Each evaluation index of four view points are presented in the study and could be utilized for alternative project evaluation systems.

• The Journal of Society for e-Business Studies
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• 제17권2호
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• pp.165-187
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• 2012

Improvements on the incumbent R&D project management structure and performance evaluation criteria in the telecommunication and broadcasting area have been called for. There have been attempts to develop alternative R&D project performance evaluation criteria. In an attempt to develop an alternative measure, this study integrates two different perspectives on R&D projects and various criteria currently being used by many foreign and domestic institutes. As a result, we have developed an alternative R&D project performance evaluation instrument. Then, we have applied the instrument to Korean cases in order to validate it. The new R&D project performance evaluation criteria can contribute to an improvement on the management of R&D projects in the telecommunication and broadcasting area.

• Journal of the Korean Institute of Intelligent Systems
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• 제12권2호
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• pp.157-163
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• 2002

The aim of this study is to establish an evaluation function that can be used in comparison of alternative layouts by quantification of particularities of arrangements. The machinery arrangement is a design phase that decides the location of various equipment in a compartment to make the most of the function of every components and to meet the limit of ship space at the same time. In case of the ship, Only one of the several alternative layouts is selected. This process depends on the experience, knowledge, and judgement of an expert and, as a result of it, it's hard to get an objective evaluation. Therefore, according to quantification by using the fuzzy theory, we suggest a standard that can objectively evaluate alternative layouts.

• Journal of the Korean Society of Manufacturing Technology Engineers
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• 제19권4호
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• pp.521-528
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• 2010

A product system will be improved continually until requirements are satisfied. It is true that considering alternative designs to improve product system is hard work; it is also true that selecting an adequate design idea that represents the needs of stakeholders concerned and meets effectiveness factors properly is not an easy work, either. In the process of driv-ing an idea and designing, which is called Design Phase, there are lots of existing tools for testing the driven idea in DFSS. But, those kinds of tools do not offer the function that helps to select the technically better design idea among alternative design ideas that have the same evaluation level. Moreover it is inappropriate to select adequate alternative design ideas by just verifying only the evaluation table in pugh matrix, since satisfied deviation val-ues are low when there is a too competitive mass product system in a market. Also, for the IT product with short life cycle, faster and more effective testing tool is needed. Therefore, the 'roduct quality index' is suggested in order to select an appropriate candidate design concept for system development that meets requirements by using 'deality concept' pro-vided by TRIZ. According to the result of this research, it is possible to select technically better idea fast and effectively; it is confirmed by applying the approach to the case of LCD BLU (Back Light Unit).

• Journal of Korea Society of Digital Industry and Information Management
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• 제9권3호
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• pp.173-185
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• 2013

In this study, the relationships of factors influencing the ways alternative types of new digital products are accepted into the market will be structuralized. On the basis of previous research, it is assumed that customers intend to use alternative types of new digital products when they have a higher value than existing products. The consumer's feeling of attraction toward the product is another factor included in the evaluation of its quality. And the attraction of the products that the consumers feel is also included in the evaluation of the qualities of the product. The results of the study indicate first that a product's value affects its attraction, but not the usage intention of the customer. Second, the benefits of the product affect the customer's recognition of its value, while cost does not. Third, environment affects recognition by the customer of the product's attraction, while knowledge of the product does not. By structuralizing the factors that influence the customer's usage intention about alternative types of new digital devices, the causal relationships of the factors involved in the acceptance of new products into the market and their success can be comprehended.

• The Korean Journal of Food And Nutrition
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• 제29권4호
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• pp.557-564
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• 2016

This study was performed to develop and evaluate beverage prepared with optimally roasted seoritae to maximize the isoflavone content and antioxidant activities of the beverage. Isoflavone content was maximized at the roasting temperature of $110^{\circ}C$ for 20 min. Both DPPH radical scavenging activity and ABTS radical scavenging activity along with total polyphenol content were highest when seoritae was roasted at $110^{\circ}C$ for 20 min. Western blotting was used to determine the level of nuclear factor of activated T-cells 1(NFATc1) involved in controlling osteoclast differentiation. The results showed that NFATc1 had a concentration-dependent inhibitory effect when the RoS110 (roasted seoritae at $110^{\circ}C$ for 20 min) samples were processed at varying concentrations (10, 50, and $100{\mu}g/mL$). Tea samples were prepared from optimally roasted seoritae by varying brewing times (5~90 min) at $65^{\circ}C$, and tea brewed for 60 min had the highest preference with $65^{\circ}C$ as the preferred temperature for drinking.

• Journal of Information Technology Services
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• 제11권3호
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• pp.1-16
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• 2012

This paper is aimed to present a fuzzy decision-making approach to deal with disaster recovery priority decision problem in information system. We derive an evaluation approach based on TOPSIS(Technique for Order Performance by Similarity to Ideal Solution), to help disaster recovery priority decision of total information system for port logistics in a fuzzy environment where the vagueness and subjectivity are handled with linguistic terms parameterized by trapezoidal fuzzy numbers. This study applies the fuzzy multi-criteria decision-making method to determine the importance weight of evaluation criteria and to synthesize the ratings of candidate disaster recovery system. Aggregated the evaluators' attitude toward preference, then TOPSIS is employed to obtain a crisp overall performance value for each alternative to make a final decision. This approach is demonstrated with a real case study involving 4 evaluation criteria(system dependence, RTO, loss, alternative business support), 7 information systems for port logistics assessed by 5 evaluators from Maritime Affairs and Port Office.

• Journal of Fisheries and Marine Sciences Education
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• 제23권3호
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• pp.503-514
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• 2011

Port Authority in Korea does not have financial independence nor fair recruitment practices, thus the prospects of the establishment of the Port Authority is not adequate. Therefore independent and effective port administration cannot be achieved. To overcome this situation, this paper examines the port administration system in Korea and identifies its problems. This paper then provides an 'modeling of Analytical Hierarchy structure' for evaluation. An alternative solution is provided by carrying out a public survey, analysing the significance of the evaluation factor using the techniques of the Analytical Hierarchy Process. The significance of profitability was identified. The role of central government is significant when assessing the public service function of port administration; and the role of the private company is significant when assessing the independence. In addition, the private company is significant when assessing profitability. The private company is the alternative for port administration in Korea, based on the evaluation of various alternatives.