• Title/Summary/Keyword: alternate treatment

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Metal base of complete denture in edentulous patient (무치악 환자에서 총의치 금속상에 대한 고찰)

  • Koo, Cheol-Ihn;Lee, Heung-Tae;Park, Chan-Ik
    • Journal of Dental Rehabilitation and Applied Science
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    • v.18 no.3
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    • pp.197-204
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    • 2002
  • Polymers are the dominant material for fabrication of denture bases. However, resin base can't fufill the patients' satisfactions completely and solve the pronunciation problem and prevent the denture fracture. In spite of many advantages, metal denture bases do not widespread in clinical practice. The main reasons are the difficulties in fabrication and additional time and cost, inability to rebase such prostheses. The use of the metal base can be one of options in complete denture treatments. This study helps, through reveiwing previous reports and literature about the metal base, metal base to be useful in the clinical application by recommend the materials, indications and advantage/disadvantage of the metal base and introduce variable designs. The clinical application of the metal base have many advantages, but the dentists have to select cases carefully and apply designs according to patient's various conditions. In conclusion, the use of the metal base can't alternate treatment of inadequate conventional complete denture. Adequate complete denture is very important for the treatment of the metal base complete denture.

Diagnosis and treatment of abnormal dental pain

  • Fukuda, Ken-ichi
    • Journal of Dental Anesthesia and Pain Medicine
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    • v.16 no.1
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    • pp.1-8
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    • 2016
  • Most dental pain is caused by an organic problem such as dental caries, periodontitis, pulpitis, or trauma. Diagnosis and treatment of these symptoms are relatively straightforward. However, patients often also complain of abnormal dental pain that has a non-dental origin, whose diagnosis is challenging. Such abnormal dental pain can be categorized on the basis of its cause as referred pain, neuromodulatory pain, and neuropathic pain. When it is difficult to diagnose a patient's dental pain, these potential alternate causes should be considered. In this clinical review, we have presented a case of referred pain from the digastric muscle (Patient 1), of pulpectomized (Patient 2), and of pulpectomized pain (Patient 3) to illustrate referred, neuromodulatory, and neuropathic pain, respectively. The Patient 1 was advised muscle stretching and gentle massage of the trigger points, as well as pain relief using a nonsteroidal anti-inflammatory and the tricyclic antidepressant amitriptyline. The pain in Patient 2 was relieved completely by the tricyclic antidepressant amitriptyline. In Patient 3, the pain was controlled using either a continuous drip infusion of adenosine triphosphate or intravenous Mg2+ and lidocaine administered every 2 weeks. In each case of abnormal dental pain, the patient's diagnostic chart was used (Fig.2 and 3). Pain was satisfactorily relieved in all cases.

Fludarabine and Rituximab in Relapsed or Refractory Hairy Cell Leukmia Variant: A Case Report and Review of Literature

  • Lee, Ji Won;Choi, Youn Mi;Yang, Jae Yun;Han, Seung Moon;Kim, Bong Seog;Nam, Seung-Hyun
    • Kosin Medical Journal
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    • v.33 no.3
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    • pp.438-445
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    • 2018
  • Hairy cell leukemia (HCL) is a rare chronic B cell leukemia morphologically characterized by cells with an abundant cytoplasm and hair-like projections that can be found in the peripheral blood and bone marrow. The treatment for HCL is splenectomy or chemotherapy with the purine analogs pentostatin and cladribine. However, patients continue to relapse. Retreatment with the same or alternate purine analogs produces lower response rates and a shorter duration of response. Fludarabine is another purine analog widely used in treating indolent lymphoid cancers, often in combination with rituximab. Here, we report a case of HCL variant in a 60-year-old man who experienced multiple relapses after splenectomy and retreatment with cladribine. The patient was then treated with fludarabine and rituximab combination chemotherapy. After the treatment, he achieved complete remission that continued for 35 months.

Patient-specific implants in reverse shoulder arthroplasty

  • Emil R Haikal;Mohamad Y. Fares;Joseph A. Abboud
    • Clinics in Shoulder and Elbow
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    • v.27 no.1
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    • pp.108-116
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    • 2024
  • Reverse total shoulder arthroplasty (RTSA) is widely popular among shoulder surgeons and patients, and its prevalence has increased dramatically in recent years. With this increased use, the indicated pathologies associated with RTSA are more likely to be encountered, and challenging patient presentations are more likely to be seen. One prominent challenging presentation is RTSA patients with severe glenoid bone loss. Several techniques with varying degrees of invasiveness, including excessive reaming, alternate centerline, bone grafting, and patient-specific implants (PSIs), have been developed to treat patients with this presentation. PSI treatment uses a three-dimensional reconstruction of a computed tomography scan to design a prosthetic implant or component customized to the patient's glenoid morphology, allowing compensation for any significant bone loss. The novelty of this technology implies a paucity of available literature, and although many studies show that PSIs have good potential for solving challenging shoulder problems, some studies have reported questionable and equivocal outcomes. Additional research is needed to explore the indications, outcomes, techniques, and cost-efficiency of this technology to help establish its role in current treatment guidelines and strategies.

Combined chemotherapy and intra-arterial chemotherapy of retinoblastoma

  • Choi, Saerom;Han, Jung Woo;Kim, Hyosun;Kim, Beom Sik;Kim, Dong Joon;Lee, Sung Chul;Lyu, Chuhl Joo
    • Clinical and Experimental Pediatrics
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    • v.56 no.6
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    • pp.254-259
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    • 2013
  • Purpose: Retinoblastoma (RB) is the most common primary malignant intraocular tumor in children. Although systemic chemotherapy has been the primary treatment, intra-arterial chemotherapy (IAC) represents a new treatment option. Here, we performed alternate systemic chemotherapy and IAC and retrospectively reviewed the efficacy and safety of this approach. Methods: Patients diagnosed with intraocular RB between January 2000 and December 2011 at Severance Children's Hospital, Yonsei University, were reviewed. Before February 2010, the primary treatment for RB was chemotherapy (non-IAC/CTX). Since February 2010, the primary treatment for RB has been IAC (IAC/CTX). External beam radiotherapy or high-dose chemotherapy were used as "last resort" treatments just prior to enucleation at the time of progression or recurrence during primary treatment. Enucleation-free survival (EFS) and progression-free survival were assessed. Results: We examined 19 patients (median age, 11.9 months; range, 1.4 to 75.6 months) with a sum of 25 eyes, of which, 60.0% were at advanced Reese Ellsworth (RE) stages. The enucleation rate was 33.3% at early RE stages and 81.8% at advanced RE stages (P=0.028). At 36 months, EFS was significantly higher in the IAC/CTX group than in the non-IAC/CTX group (100% vs. 40.0%, P=0.016). All 5 patients treated with IAC achieved eye preservation, although most patients were at advanced RE stages (IV-V). Conclusion: Despite the limitation of a small sample size, our work shows that an alternative combined approach using IAC and CTX may be safe and effective for eye preservation in advanced RB.

A Study on the Conservation of Lady Shim's Costume Excavated in Jecheon Province (제천출토 청송심씨 출토유물의 보존처리)

  • Park, Bong Soon;Lee, Mok Kun;Chang, In Woo
    • Journal of the Korean Society of Costume
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    • v.65 no.7
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    • pp.47-59
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    • 2015
  • This paper studies the conservation treatment of Lady Shim's costume, which was excavated in Jecheon Province in 2012. There were the significant problems, which were encountered in the treatment of the costume ; First the Jeogoris were transformed during the excavation, Second fibers were seriously deteriorated, Third most of the fabrics such as Chusa were readily deformed. To overcome these problems and to secure stability in the conservation treatment, we decided to alternate between two different washing methods ; dry cleaning by n-hexane and wet cleaning by water. The costume shape was recovered by steaming and by swelling with Hanji(Korean traditional paper). The combined cleaning method proved to be relatively efficient and stable. In addition, the shape of Chusa was well preserved by dry cleaning.(using n-hexane also solved the problem of bad smell after washing with organic solvents.) The effects of the conservation treatment on the excavated costumes could be seen in the change of Lab color difference. Washing made the distribution of Lab color difference narrower, which may suggest that the impurities on the fiber was removed by washing. In addition, the value of L was greater than a-value and b-value after the treatment. This result indicates that the change of value represents the change of color difference by cleaning.

A comparison of analgesic efficacy and safety of clonidine and methylprednisolone as additives to 0.25% ropivacaine in stellate ganglion block for the treatment of complex regional pain syndrome: a prospective randomised single blind study

  • Sreyashi Naskar;Debesh Bhoi;Heena Garg;Maya Dehran;Anjan Trikha;Mohammed Tahir Ansari
    • The Korean Journal of Pain
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    • v.36 no.2
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    • pp.216-229
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    • 2023
  • Background: The role of the sympathetic nervous system appears to be central in causing pain in complex regional pain syndrome (CRPS). The stellate ganglion block (SGB) using additives with local anesthetics is an established treatment modality. However, literature is sparse in support of selective benefits of different additives for SGB. Hence, the authors aimed to compare the efficacy and safety of clonidine with methylprednisolone as additives to ropivacaine in the SGB for treatment of CRPS. Methods: A prospective randomized single blinded study (the investigator blinded to the study groups) was conducted among patients with CRPS-I of the upper limb, aged 18-70 years with American Society of Anaesthesiologists physical status I-III. Clonidine (15 ㎍) and methylprednisolone (40 mg) were compared as additives to 0.25% ropivacaine (5 mL) for SGB. After medical treatment for two weeks, patients in each of the two groups were given seven ultrasound guided SGBs on alternate days. Results: There was no significant difference between the two groups with respect to visual analogue scale score, edema, or overall patient satisfaction. After 1.5 months follow-up, however, the group that received methylprednisolone had better improvement in range of motion. No significant side effects were seen with either drug. Conclusions: The use of additives, both methylprednisolone and clonidine, is safe and effective for the SGB in CRPS. The significantly better improvement in joint mobility with methylprednisolone suggests that it should be considered promising as an additive to local anaesthetics when joint mobility is the concern.

Systematic Propagation of High Quality Garlic (Allium sativum L.) Through Shoot Apical Meristem Culture 1. Organogenesis from in Vitro Cultured Shoot-tips (생장점배양에 의한 우량마늘 체계적 증식 1.생장점배 양으로부터 기관형성)

  • Lee, Eun-Mo;Lee, Young-Bok
    • Korean Journal of Plant Tissue Culture
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    • v.21 no.3
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    • pp.161-166
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    • 1994
  • Since garlics (Allium sativum L.) are propagated through cloves, infection by virus or other pathogens may become severe problem if not using high quality seed bulbs every year resulting in the reduction of yield and bulb quality, In order to solve this problem, the establishment of virus-free bulb production and its supply system have been required because no chemicals were found to eliminate viruses from seed bulbs. This experiment was conducted to develop an effective production technique of high quality seed bulbs using shoot-tip culture. Over 90% of shoot-tips explanted on January L 1990 were survived at constant temperature of either 20, 24 or 28$^{\circ}C$, wheres 88% at alternate temperature (28/20$^{\circ}C$). The growth of shoot and root was most vigorous at constant 24$^{\circ}C$, and least at alternate temperature (28/20$^{\circ}C$) condition. When shoot-tips were explanted June 21 to August 1,1991, survival and growth of shoot-tips was most vigorous on MS medium supplymented with 0.1 mg/L NAA and 2 mg/L kinetin and least 1 mg/L Gh$_3$. The shoot-tips taken from the seed bulbs stored at 4$^{\circ}C$ for 15 to 60 days were placed on MS medium, shoot growth and in vitro bulblet formation increased slightly as affected by the increase of told treatment period at 4$^{\circ}C$.

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Change of RIII Reflex of Primary and Secondary Hyperalgesia Site by High Voltage Pulsed Current (고전압맥동전류에 의한 일차 및 이차통각과민대의 RIII 반사의 변화)

  • Kim, Su-Hyon;Choi, Sug-Ju;Lee, Jung-Woo;Jeong, Jin-Gyu;Kim, Tae-Youl;Kim, Gye-Yeop
    • Journal of the Korean Academy of Clinical Electrophysiology
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    • v.4 no.1
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    • pp.1-12
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    • 2006
  • This study conducted RIII reflex measurement to examine degree of pain depending on polarity of high voltage pulsed current of primary and secondary hyperalgesia site in hyperalgesia rat by local thermal injury. Hind paw which was injury site was taken as primary hyperalgeisa site, sole which was injury adjacent site was taken as secondary hyperalgesia site, and mechanical pain threshold, thermal pain threshold and root mean square of RIII reflex were measured. This study was conducted with control group I of hyperalgesia rat at hind paw by thermal injury and experimental groups divided into cathodal high voltage treatment group II, anodal high voltage treatment group III and alternate high voltage treatment group IV, applied active electrode of high voltage pulsed current to hind paw directly, placed reference electrode on the sole of injury adjacent site and applied pulse frequency. It measured RIII reflex and obtained the following results: Root mean square of RIII reflex at primary hyperalgeisa site was significantly reduced in group II after 2 days of hyperalgesia. Group II showed significant decrease after 5 and 6 days of hyperalgesia. Root mean square of RIII reflex at secondary hyperalgesia site showed significant reduction in group II after 6 days of hyperalgesia. Consequently it was found that application of high voltage pulsed current of hyperalgesia site reduced RIII reflex at primary hyperalgeisa site and secondary hyperalgesia site by electrical stimuli. Effects by polarity of high voltage pulsed current showed the greatest reduction of pain threshold when cathodal active electrode was used.

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Effects of Waste Nutrient Solution on Growth of Chinese Cabbage (Brassica campestris L.) in Korea

  • Choi, Bong-Su;Lee, Sang-Soo;Ok, Yong-Sik
    • Korean Journal of Environmental Agriculture
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    • v.30 no.2
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    • pp.125-131
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    • 2011
  • BACKGROUND: Reuse of waste nutrient solution for the cultivation of crops could lead to considerable conservation of water resources, plant nutrients, and water quality. Therefore, this study was conducted to evaluate the potential for reducing the use of chemical fertilizer in Chinese cabbage cultivation via the reuse of waste nutrient solution as an alternative irrigation resource. METHODS AND RESULTS: The nutrients supplied in the waste nutrient solution consisted of 1474.5, 1285.1, 991.6, and 872.6 mg/L for $K+$, ${NO_3}^-$, $Ca^{2+}$ and ${SO_4}^{2-}$, respectively. At 56 days after transplanting (DAT), the leaf length of Chinese cabbage plants irrigated with the waste nutrient solution treatment was significantly higher than that of plants irrigated using a conventional groundwater treatment. Additionally, the leaf width, fresh weight and dry weight of the plants irrigated with the waste nutrient solution were similar or greater than that of plants irrigated with a conventional treatment. Furthermore, the growth of plants treated with the waste nutrient solution +25% fertilizer was the highest among all tested treatments. CONCLUSION(s): These results indicate that the waste nutrient solution can be used as an alternate water resource for crop cultivation. In addition, it can contribute to reduce the fertilizer and to obtain the higher crop yield of Chinese cabbage.