• Journal of Physiology & Pathology in Korean Medicine
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• v.24 no.6
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• pp.1099-1104
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• 2010

Aim of this study was to determine if obesity or abdominal obesity is more prevalent in persons with allergic rhinitis compared with healthy persons and to determine if obesity or abdominal obesity affects severity of rhinitis's symptoms. We studied 44 allergic rhinitic patients and 47 healthy persons. BMI and WHR were measured by the In-body 520. And severity of rhinitis's symptoms were assessed by questionnaires. The prevalence of obesity in allergic rhinitis group(27.3%) was significantly higher than control group(10.6%). And the prevalence of abdominal obesity in allergic rhinitis group(43.2%) was higher than control group(40.4%), but was not statistically significant. Nasal obstruction score of obesity group was higher than control group, but was not statistically significant. And nasal obstruction, Korean Allergic Rhinitis Specific Quality of Life Questionnaire (KARQLQ) score of abdominal obesity group were significantly higher than control group. And when age and sex are corrected, allergic rhinitis and obesity's association was statistically significant. The prevalence of obesity in allergic rhinitis group was significantly higher than control group. Also when age and sex are corrected, allergic rhinitis and obesity's association was statistically significant. And nasal obstruction score was higher in obesity than control group, but was not significant. The other side, nasal obstruction and KARQLQ score in abdominal obesity group was significantly higher than control group. Thus, we thought that fixed various confounding factors and large-scale studies will be needed.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.33 no.2
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• pp.186-196
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• 2020

Objectives : This study is to report a case of chronic allergic contact dermatitis, treated with Korean medicine, primarily focused on Oryeong-san. Methods : A 43-year-old female has suffered from dermatitis in axillary, lower abdominal, inguinal and popliteal area for more than 10 years. She was diagnosed with chronic allergic contact dermatitis accompanied by skin symptoms such as severe pruritus, erythema, skin pigmentation, papules and lichenification, and by decreased quality-of-life. She received Korean medicine treatment including herbal medicine, acupuncture and herbal external medication for 4 months. Results : The skin symptoms such as pruritus, erythema, skin pigmentation, papules and lichenification were remarkably improved. Also, the NRS of pruritus changed from 10 to under 1, and the DLQI score changed from 29 to 6. Conclusions : This case report suggests that Korean medicine, especially Oryeong-san may have a role in treating skin symptoms such as pruritus, erythema, skin pigmentation, papules and lichenification in the patients diagnosed with chronic allergic contact dermatitis. Also, the improvement of skin symptoms treated with Korean medicine may result in quality-of-life improvement in those patients.

• Journal of Sasang Constitutional Medicine
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• v.32 no.1
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• pp.50-57
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• 2020

Objectives Allergic reaction to antibiotics is associated with increased use. And rate of Irritable Bowel Syndrome(IBS) is on the increase associated with stress, depression, anxiety, or previous intestinal problem. This case study reports significant improvement of patients with diarrhea accompanied by IBS who had suffered from allergic reaction to antibiotics after treatment with Sasang constitutional medicine. Methods This patient was diagnosed as Taeeumin type. Sasang constitutional medicine was taken by the patient, almost three times per day during treatment periods. We measured the degree of the main symptoms such as diarrhea, abdominal discomfort, insomnia, itching etc, using Visual Analogue Scale(VAS). Results The symptoms of diarrhea, abdominal discomfort, and insomnia were improved. VAS score was decreased from 4~5 to 0~1 for about two weeks. Conclusions This case shows that Sasang constitutional medicine treatment can contribute to improve main symptoms accompanied by IBS.

• Journal of the Korean Society of Food Culture
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• v.11 no.1
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• pp.123-130
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• 1996

This study was designed to investigate clinical features, allergy-inducing substances as well as foods, and nutritional behavior of allergic patients. Sixty-eight adult male and 78 adult female patients were surveyed by using the self-developed questionnairs. The results were as follows: 1. The common target organs of allergic symptoms included bronchus, skin and nose. 2. 37.7% of the subjects did not recognize their allergy inducing substances. Among the known substances, house-dust mite, food, temperature and weather change, pollens, smoke, air pollution materials, drugs and even stress provoked symptoms. 3. As for the food allergy, a number of foods were found to be implicated in allergic reactions. These foods included pork, chicken, seafoods such as mackerel, crab & shrimp, milk, egg, peanut, apple and pupa. Symptoms and signs of food reactions included urticaria, asthma, and rhinitis. 4. The nutrition adequacy ratio (NAR) of energy was below 0.75 for male patients and about 0.80 for female patients. And 24.0% of the subjects were regarded as excellent, 31.5% as fair, and 44.5% as poor in food related behavior evaluation.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.27 no.4
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• pp.243-250
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• 2014

Objective : The purpose of this report is to know the effect of oriental medical treatments on acute allergic contact dermatitis with multiple nummular eczema. Methods : We treated a 34-years-old woman patient with acute allergic contact dermatitis on face and multiple nummular eczema on both arm, right ankle and left inguinal region by Korean medicine. After Korean medical treatment for 42 days in hospital, we measured the decrease of exudation and pruritis as well as recovery of skin damages. We recorded pictures of changes on symptoms. Results & Conclusion : The symptoms of ACD and nummular eczema were significantly improved except scars. Exudation and pruritis were disappeared and skin damages were almost recovered until discharge from hospital. After 20 days we could confirm the symptoms were clearly disappeared. Thus Korean medical treatments are effective on ACD and nummular eczema.

• The Journal of Pediatrics of Korean Medicine
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• v.17 no.2
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• pp.103-114
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• 2003

Objective : Prevalance of allergic rhinitis in pediatric population appear to be rising. About acupuncture and herbal medicine treatment on allergic rhinitis is occasionally reported, but few treatment of using herbal medicine distillate was reported. The aim of this study was to investigate effect of Tongkyu-tang distillate on pediatric allergic rhinitis. Methods : Twenty patients treated in our hospital between January 2002 and December 2002, treated with Tongkyu-tang distillate were studied. Result : We treated pediatrc allergic rhinitis with Tongkyu-tang distillate spray on nasal cavity. and so the symptoms of allergic rhinitis were improved effectively Conclusion : We had effective results of Tongkyu-tang distillate on pediatric allergic rhinitis comparatively. And we wish that much more new treatment methods of allergic rhinitis are investigated.

• Biomolecules & Therapeutics
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• v.19 no.4
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• pp.466-471
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• 2011

Allergic asthma is complex inflammatory airway disorder caused by genetic and environmental factors. Sulfamethoxazole, a sulfonamide, is the cause of drug rash with eosinophilia and systemic symptoms syndrome. Parasites infection also related with eosinophilia and allergic diseases. In the present study, we investigated the modulating effects of parasitic derivative and sulfamethoxazole (SMX) on allergic airway inflammation in the ovalbumin (OVA)-induced murine asthma model. Histopathological changes, cytokine secretion, and total and allergen-specific IgE were investigated. BALB/c mice were treated with Ascaris suum extract or SMX for 4 weeks before sensitized and challenged to ovalbumin. Pre-treatment of Ascaris suum extract decreased allergic inflammation in lung tissue and IL-4, total IgE, and OVA-specific IgE levels in bronchoalveolar lavage fluid. However, pre-treatment of SMX did not show any effects on allergic airway inflammation. These results indicate that parasitic infection has protective effects on allergic asthma, but the sulfamamides may not relate with allergic asthma.

• Herbal Formula Science
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• v.24 no.1
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• pp.63-70
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• 2016

Objective This study is designed to investigate the effect of Korean medical therapy on Allergic purpura patients.Method This is a case report on a male and a female patients who has been suffering from allergic purpura. To reduce her symptoms, we provided with internal herbal medicine 2-3 times a day, acupuncture therapy 1-2 times a day.Results After series of treatments, the symptoms of allergic purpura were remarkably improved.Conclusions This study shows us that Korean medical treatments has remedial values for purpura patients. Hence, more studies should be demanded in Korean medicine for elevation of treatment rate.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.16 no.3
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• pp.210-219
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• 2003

Objectives : This study is to suggest a kind of guide line of dietary therapy in allergic diseases. Methods : We investigated frequency, symptoms and implicating foods of food allergy, and experience, methods, periods, results and necessity of dietary therapy of 49 patients with allergic diseases by using self-report questionnaires. The data were analyzed by SPSS／PC+ program using frequency, Chi-square test(p〈0.05) and Pearson correlation coefficient(p〈0.01). Results : 1. The frequency of food allergy was 49% and skin symptoms were the most common. 2. The most implicating foods were chicken, flour, milk, pork and egg in order. 3. 36.7% of patients had experienced dietary therapy and 47.4% of them had stated mild improvement. 4. Over 80% of patients perceived necessity of dietary therapy and there is significant correlation between necessity of dietary therapy and sum of food allergens(r=368). Conclusions : Dietary therapy is recommended as supplementary therapy in allergic diseases and it needs to be established based on the real conditions and Korean Oriental medical theory.

• The Journal of Korean Medicine
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• v.20 no.2
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• pp.98-107
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• 1999

This study aimed to find out Oyo-Tang's effects on allergic asthma using the Egg-White Implant(EWI) method model recommended by Siqueira et al. Oyo-Tang has widely been prescribed and used in Oriental Medicine for controlling and curing of cough, nasal obstruction, pharyngeal pain and hoarseness. Previous studies have demonstrated that Oyo-Tang has analgesic, sedative, anticonvulsive, antitussive and antihistamine effects. But it was uncertain whether Oyo-Tang could inhibit the allergic reactions, to alleviate the symptoms of allergic asthma. With such aim. the respiratory patterns and eosinophil infiltration in the tracheal mucosa of rats with experimentally induced allergic asthma (using EWI method) were mainly observed. The results are as follows: 1. Oyo-Tang decreased the number of poor respiration with respect to control group (P<0.05) 2. Oyo-Tang decreased the number of eosinophils infiltrated in tracheal mucosa with respect control group (P<0.05). The above results demonstrate that Oyo-Tang has the inhibitory effects on the process allergic asthma and suggest that it could be used in relieving patients of the symptoms caused allergic asthma.