• 제목/요약/키워드: alcoholic problem

검색결과 35건 처리시간 0.032초

한국인 알코올중독 환자의 예후인자에 관한 연구 : 심리적, 사회적, 생물학적 요인을 중심으로 (A Study for The Prognostic Indicators of Korean Alcoholics in Psychological, Social and Biological Aspects)

  • 성상경;장환일
    • 생물정신의학
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    • 제2권2호
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    • pp.218-236
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    • 1995
  • The author studied prognostic indicators of sixty Korean male alcoholics in psychological, social and biological aspects who were divided into abstinent and drinking groups. Thirty patients were assigned to each group. They were controlled in age and sex. Both groups were compared in terms of the demographic characteristics, past drinking history, treatment history, famaily history, ego strength and personality factors differences and distribution of dopamine $D_2$ receptor gene Al allele. Also the author studied relation of clinical course, alcoholic family history and dopamine $D_2$ receptor gene Al allele in both groups. The results were as follows; 1) The abstinent group had higher rate of married state, higher economic status, longer education years and maintained more stable job than the drinking group. But made no differences in occupation and religion. 2) The abstinent group showed higher rate of living with family members than the drinking group, and wives and fellows of the alcoholics anonymous were important factors for maintenance of abstinence. Family loading and parent's characters were not different. 3) The abstinent group had longer maximal length of abstinence but mean amount of alcohol consumption per day were larger than the drinking group. But there were no differences in duration of past drinking, drinking pattern, main drinking time, first drinking age and preference of the kind of alcoholic beverage in the past drinking history. 4) The abstinent group showed stronger treatment motivation, absolute abstinence in treatment goal, more voluntary adimission and maintained longer therapeutic relationship otter discharge than the drinking group. But both groups showed negative attitude toward antabuse therapy. 5) The abstinent group had higher mean score in ego strength scale than the drinking group. 6) In the personality factor questionnaire, the abstinent group showed strong laugh poise and the trait of praxernia, conservatism personality but the drinking group showed tough poise, the trait of weak ego strength(unstableness) and tough mindedness personality. 7) In comparision of dopamine $D_2$ receptor gene A1 allele, the prevalence of A1 allele was seventy percent and the frequency was 0.38 in the abstinent group. The prevalence of A1 allele was sixty percent and the frequency was 0.42 in the drinking group. Both groups were not significantly different in A1 allele prevalence and frequency. 8) In comparision of dopamine $D_2$ receptor gene A1 allele according to alcoholic family history, the prevalence of A1 allele was seventy percent and the frequency was 0.43 in the family history positive group. The prevalence of A1 allele was sixty-one percent and the frequency was 0.38 in the family history negative group. Both groups were not significantly different in A1 allele prevalence and frequency. In comparision of past drinking history according to alcoholic family history, the family history positive group showed earlier first drinking and problem drinking, but the family history negative group hod longer duration of past drinking. The mean amount of alcohol consumption per day, the longest duration of abstinence and Alcoholism Screening Test of Seoul Natoinal Mental Hospital(NAST) results were not significant. In conclusion, the results suggest that successful prognostic indicators of Korean alcoholics are married state, higher economic status, longer education years, stable job, living with family members, longer abstinence during past drinking history, strong treatment motivation, absolute abstinence in treatment goal, voluntary adimission, maintained therapeufic relationship, strong ego strength and the trait of praxernia, conservatism personality. But occupation, religion, alcoholic family history, parent's characters, duration of past drinking, drinking pattern, main drinking time, first drinking age, preference of the kind of alcoholic beverage, attitude to antabuse therapy and distribution of dopamine $D_2$ receptor A1 allele were not significantly related to the prognostic indicators of Korean alcoholics.

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비만아에서 비알코올성 지방간염의 위험요인 (Risk Factors of Non-alcoholic Steatohepatitis in Childhood Obesity)

  • 윤은실;박용훈;최광해
    • Pediatric Gastroenterology, Hepatology & Nutrition
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    • 제10권2호
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    • pp.179-184
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    • 2007
  • 목 적: 비만 인구 증가와 함께 비알코올성 지방간염의 유병율이 증가하고 있어 이에 대한 관심이 높아지고 있지만, 비만아 중 비알코올성 지방간염 발생의 위험요인에 대한 연구는 별로 없는 실정이어서, 비만아 중 비알코올성 지방간염을 예측할 수 있는 위험 요인을 알아보고자 하였다. 방 법: 영남대학교 병원 소아 비만 클리닉을 방문한 비만아 84명을 대상으로 하였으며, ALT 40 IU/L 이하 (Group 1), 41 IU/L 이상(Group 2)로 나누었으며, 간염이 있는 경우에는 다른 원인에 의한 간염은 배제 시켰으며 나이와 총콜레스테롤, 고밀도와 저밀도 지단백 콜레스테롤, 중성지방, 비만도, 체지방률을 비교하고 빈도를 분석하였다. 결 과: 연령, 총콜레스테롤, 고밀도와 저밀도 지단백 콜레스테롤, 중성지방, 비만도, 체지방율의 평균을 비교하였을 때 1군에서는 연령이 $10.5{\pm}1.6$세, 2군은 $10.7{\pm}2.0$세였으며, 총콜레스테롤은 1군에서 $183.0{\pm}29.1$ mg/dL, 2군에서 $183.7{\pm}31.3$ mg/dL였고, 고밀도 지단백 콜레스테롤은 1군, 2군 각각 $53.0{\pm}10.2$ mg/dL, $55.7{\pm}13.0$ mg/dL, 저밀도 지단백 콜레스테롤은 1군에서 $113.4{\pm}30.2$ mg/dL, 2군에서 $113.0{\pm}30.0$ mg/dL, 중성지방은 1군에서 $99.4{\pm}62.9$ mg/dL, 2군에서 $114.2{\pm}47.3$ mg/dL, 비만도는 1군에서 $44.7{\pm}12.2%$, 2군에서 $47.9{\pm}15.1%$, 체지방률은 각각 $32.7{\pm}5.0%$, $34.0{\pm}4.8%$로 두 군 간에 통계적으로 유의한 차이가 없었으나, 이상지혈증의 분포는 총콜레스테롤, 고밀도와 저밀도 지단백 콜레스테롤은 두 군에서 통계적으로 유의한 차이가 없었으나, 중성지방은 110 mg/dL 이상인 경우가 1군에서 13명(28.9%), 2군에서 21명(53.8%)으로 2군에서 통계적으로 유의하게 많았다(p-value=0.023). 결 론: 비만아에서 비알코올성 지방간염을 예측할 수 있는 위험요인으로 중성지방이 유용할 것으로 생각된다.

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고등학생을 대상으로 한 약물남용 예방 프로그램의 효과 -음주와 흡연을 중심으로- (The Effect of Substance Abuse Prevention Program on High School Students - focused on alcohol and smoking)

  • 홍정이;강희숙
    • 보건교육건강증진학회지
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    • 제20권3호
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    • pp.61-76
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    • 2003
  • Substance abuse among teenagers has been spreading widely and become a serious social problem. However, teachers hardly realize its importance. Recently, substance abuse prevention programs show a tendency towards one time education. This study aims to research the effect of substance abuse prevention on high school students using the Life Skills Training Program. Two classes(36 students in the experimental group, 35 in the control group) at W High School in Daejeon were randomly sampled for this study from May to June 2002. Substance knowledge and attitude, problem solving, and assertiveness were examined as Pre and Post-Tests. The data was analyzed using frequencies, t-test, means, and covariance(ANCOVA). The results of this study were as follows; 1. Compared with the control group, substance knowledge in the experimental group was significantly improved(F=176.317, P=.000). And compared with the control group, substance attitudes in the experimental group were improved significantly.(F=207.682, P=.000). 2. Compared with the control group, cognitions to problem solving in the experimental group was significantly improved(F=100.937, P=.000). 3. Compared with the control group, assertiveness behaviors in the experimental group were increased significantly(F=207.255, P=.000). The study showed that Substance Abuse Prevention of High School Students was effective in improving substance knowledge and attitude, cognition to problem solving, and assertiveness behavior. Some suggestions based on the result are as follows; 1. Substance abuse preventive programs must be practiced properly and systematically with high school students in their regular classes. 2. Various preventive education programs must be developed for substance abuse where high school students can join in a community center, such as Community Welfare Center, Alcoholic Counseling Center, and Mental Health Center. 3. For the furthering of substance abuse preventive education, there must be continued research about not only students with problems of substance misuse and abuse, but also students without them. 4. There must be early determination of students with problems of substance misuse to be able provide school social workers with the opportunity for intervention.

Effect of probiotics Lactobacillus paracasei GKS6, L. plantarum GKM3, and L. rhamnosus GKLC1 on alleviating alcohol-induced alcoholic liver disease in a mouse model

  • Tsai, You-Shan;Lin, Shih-Wei;Chen, Yen-Lien;Chen, Chin-Chu
    • Nutrition Research and Practice
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    • 제14권4호
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    • pp.299-308
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    • 2020
  • BACKGROUND/OBJECTIVES: Heavy alcohol consumption causes the development of alcoholic liver disease (ALD), a neglected but important public health problem. Many studies have pointed out that probiotics could improve gut health, which is also considered to be a cause of ALD. Therefore, this study screened the probiotics, Lactobacillus casei GKC1 (GKC1), L. fermentum GKF3 (GKF3), Bifidobacterium lactis GKK2 (GKK2), L. rhamnosus GKLC1 (GKLC1), L. paracasei GKS6 (GKS6), and L. plantarum GKM3 (GKM3), for their potential benefits in alleviating ALD for applications to disease prevention. SUBJECTS/METHODS: C57BL/6N mice were divided into 8 groups (n = 6 in each): normal control, positive control (alcohol-diet fed), and treatments of feeding probiotics GKC1, GKF3, GKK2, GKLC1, GKS6, and GKM3 under an oral dose 0.82 g/kg B.W. per day by oral gavage. The experiment was conducted for 8 weeks, and the concentrations of alanine aminotransferase (ALT), aspartate aminotransferase, triglyceride (TG), and total cholesterol (TC) in mice were measured. The glutathione (GSH), catalase (CAT), and histology were analyzed after sacrifice. RESULTS: The results showed a decrease in the serum ALT, liver TG, and liver TC levels in the GKS6, GKM3, and GKLC1 groups compared to the positive control. In addition, the decreasing GSH and CAT levels were inhibited in the GKS6 and GKM3 groups. The histopathological results showed that all probiotics could reduce the accumulation of liver fat. Furthermore, there was a significant difference in GKLC1 with lower stomach damage compared to the alcohol-fed mice without any addition of probiotics. CONCLUSIONS: GKLC1, GKS6, and GKM3 can be used as supplements for alleviating the development of ALD.

여성알코올중독환자의 소양증에 관한 연구 (A study on pruritus of female alcoholics)

  • 김동현;김희경
    • 한국산학기술학회논문지
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    • 제14권9호
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    • pp.4412-4420
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    • 2013
  • 알코올은 인체에 영향을 미치지 않는 곳이 없을 정도로 여러 질환들을 야기 시킨다. 이로 인해 알코올중독과 관련된 여러 연구가 진행되고 있으나 알코올중독환자의 피부질환에 관련된 연구는 국내에서 찾아보기 어렵다. 이에 민감한 피부를 가진 여성알코올중독환자의 피부질환중 소양증에 관한 연구를 하였다. 2013년 05월 1일~2013년 5월 20일까지 전국의 알코올중독치료병원 4곳에서 여성알코올중독환자 114명의 설문지와 청주, 성남시 일반인 106명의 설문지를 토대로 비교연구를 하였고, 연구 결과 알코올중독환자가 일반인에 비해 소양증 점수가 더 높았고, AUDIT-K점수와 소양증점수는 양의 상관관계가 있는 것으로 나타났으며, 음주주기, 음주량도 소양증에 관련이 있는 것으로 나타났다. 이 연구 자료가 알코올중독 환자의 피부치료의 기초자료로 활용되며 앞으로 알코올중독환자의 피부연구의 활성화를 기대한다.

알코올 중독자 가정 자녀의 적응과정에 관한 근거이론 접근 (A study on the process of children's adjustment following a parent's alcoholism - a grounded theory based approach -)

  • 주소희
    • 한국가족복지학
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    • 제23호
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    • pp.225-262
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    • 2008
  • 본 연구는 '알코올 중독자 가정 자녀의 적응과정은 어떠한가?' 라는 연구문제를 가지고 알코올 중독자 가정에서 성장한 만 18세 이상 성인자녀의 적응과정을 심층적으로 탐색한 것이다. 이를 위해 알코올 중독자 가정자녀 8명을 대상으로 심층면접을 한 후 Strauss와 Corbin(1998)의 근거이론방법을 활용하여 분석하였다. 연구참여자들의 근거자료를 분석 한 결과, 알코올 중독자 가정 자녀가 경험하는 중심현상은 존재부정, 억눌림으로 분석되었다. 이에 대한 인과적조건, 맥락적조건, 중재적조건, 작용/상호작용전략과 결과를 통합한 핵심범주는 '부모의 알코올 문제로부터 자신을 분리하여 자아를 재정립함'으로 구체화되었다. 또한 자녀들의 적응과정은 혼란과 억압단계, 갈등단계, 인식과 분리단계, 수용단계의 과정으로 이루어지는 것으로 나타났다. 이러한 연구결과는 알코올 중독자 가정자녀의 적응에 대한 이론 구축과 사회복지실천의 방향제시에 함의를 가진다.

Lospector : 지역특산물 정보서비스를 위한 mRFID 검색 시스템 (The mRFID retrieval system for a product information service)

  • 오정진;최성민;최한석
    • 한국콘텐츠학회:학술대회논문집
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    • 한국콘텐츠학회 2008년도 춘계 종합학술대회 논문집
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    • pp.104-107
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    • 2008
  • 최근 모바일 RFID 기술은 기존의 RFID 기술과 이동통신기술과의 융합으로 다양한 부분에 연구 활용되고 있다. 그에 따라, 새로운 모바일 RFID 코드 체계의 확립과 검색 시스템의 연구 및 개발이 진행되고 있다. 이렇게 연구 및 개발이 진행되고 있는 검색 시스템은 각 응용 분야에 적절하게 활용되지 못하는 문제점이 있다. 이에 따라, 본 논문에서는 새롭게 Lospector라는 지역특산물을 이용한 모바일 RFID 검색시스템을 제안하여 검색 시스템이 각각의 서비스 분야에 적절하게 활용되지 못하는 문제점을 개선하고 효율적인 검색기술을 제시 한다.

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Non-alcoholic Fatty Liver Disease (NAFLD) and Significant Hepatic Fibrosis Defined by Non-invasive Assessment in Patients with Type 2 Diabetes

  • Sobhonslidsuk, Abhasnee;Pulsombat, Akharawit;Kaewdoung, Piyaporn;Petraksa, Supanna
    • Asian Pacific Journal of Cancer Prevention
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    • 제16권5호
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    • pp.1789-1794
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    • 2015
  • Background: Non-alcoholic fatty liver disease (NAFLD), the most common liver problem in diabetes, is a risk factor for liver cancer. Diabetes, high body mass index (BMI) and old age can all contribute to NAFLD progression. Transient elastography (TE) is used for non-invasive fibrosis assessment. Objectives: To identify the prevalence of NAFLD and significant hepatic fibrosis in diabetic patients and to assess associated factors. Materials and Methods: One hundred and forty-one diabetic and 60 normal subjects were screened. Fatty liver was diagnosed when increased hepatic echogenicity and vascular blunting were detected by ultrasonography. Liver stiffness measurement (LSM) representing hepatic fibrosis was assessed by TE. LSM ${\geq}7$ kPa was used to define significant hepatic fibrosis. Results: Four cases were excluded due to positive hepatitis B viral markers and failed TE. Diabetic patients had higher BMI, systolic blood pressure, waist circumference and fasting glucose levels than normal subjects. Fatty liver was diagnosed in 82 (60.7%) diabetic patients but in none of the normal group. BMI (OR: 1.31; 95%CI: 1.02-1.69; p=0.038) and alanine aminotransferase (ALT)(OR: 1.14; 95%CI: 1.05-1.23; p=0.002) were associated with NAFLD. Diabetic patients with NAFLD had higher LSM than those without [5.99 (2.4) vs 4.76 (2.7) kPa, p=0.005)]. Significant hepatic fibrosis was more common in diabetic patients than in normal subjects [22 (16.1%) vs 1 (1.7%), p=0.002]. Aspartate aminotransferase (AST)(OR: 1.24; 95%CI: 1.07-1.42; p=0.003) was associated with significant hepatic fibrosis. Conclusions: Sixty and sixteen percent of diabetic patients were found to have NAFLD and significant hepatic fibrosis. High BMI and ALT levels are the predictors of NAFLD, and elevated AST level is associated with significant hepatic fibrosis.

당뇨병이 없는 알코올중독 환자에서 광범위한 뇌병변을 보인 저혈당성 뇌병증 1예 (A Case of Severe Hypoglycemic Encephalopathy with Extensive Brain Lesions in Non-diabetics and Alcoholism)

  • 빈창훈;박민수;이세진
    • Journal of Yeungnam Medical Science
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    • 제27권1호
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    • pp.37-41
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    • 2010
  • Hypoglycemic encephalopathy is a rare problem among diabetic patients who are receiving treatment with insulin or other glucose-lowering drugs. The MRIs of patients with hypoglycemic encephalopathy commonly show scattered lesions in the cerebral cortex, hippocampus and basal ganglia, but lesions in the cerebellum or brain stem are extremely rare. A 44-year-old alcoholic woman without diabetes was admitted with a semicomatose mentality and seizure with severe hypoglycemic encephalopathy with extensive brain lesions seen on MRI at the middle cerebellar peduncle and midbrain, as well as in the other brain areas.

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Structural Relationship between Psychosocial Factors Affecting Motivation for Change in Alcoholics

  • Baik, Ok Mi
    • International Journal of Advanced Culture Technology
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    • 제7권3호
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    • pp.103-110
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    • 2019
  • The purpose of this study was to investigate the relationship between psychosocial factors, such as self-esteem, stress coping, and social support, and motivation for change in alcohol dependent inpatients. This study included 179 inpatients in the 7clinics for alcoholic in Chonbuk. For the analysis of the study questions, this study utilized the structural equation modeling. The results show that self-esteem was related to motivation for change with mediating role of problem-focused stress coping strategy in alcohol dependent inpatients. The study also reveal that self-esteem and social support was directly associated with the motivation for change. Based on the findings, the importance of programs to promote self-esteem and the involvement of family and acquaintances in the treatment process has been suggested.