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The Effects of Sunbanghwalmyung-eum Extract on Anti-oxidant, Anti-allergic and Anti-inflammatory ability in mouse cell (Mouse cell에서 선방활명음(仙方活命飮)의 항산화작용과 항알러지 및 항염증 효과)

  • Park, Min-Chul;Hong, Seung-Ug
    • The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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    • v.21 no.2
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    • pp.46-53
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    • 2008
  • Background and Objectives : The aim of this study was to investigate the anti-oxidant, anti-allergic and anti-inflammatory ability of the Taglisodog-eum(SHE) extract on the RAW 264.7 and EL4 cells Materials and Methods : Three types of experiments were implemented for this study: first, the experiment to study the anti-oxidant effect of SHE using Riboflavin; second, in vitro experiment to investigate the inhibition of Th 2 cell differentiation by SHE using EL4 cells (IL-4 mRNA expression); third, the suppression of $NF-{\kappa}B$ activation using RAW 264.7 cells (iNOS and COX-2 mRNA expression). Results : The anti-oxidant ability of SHE were dose-dependantly increased. From in vitro, the LPS-induced iNOS and COX-2 mRNA expression were dose-dependantly decreased in the RAW264.7 cells treated with SHE and the PMA-induced IL-4 mRNA expression were also dose-dependantly decreased in EL4 cells. $NF-{\kappa}B$ activation was suppressed, and iNOS & COX-2 production were inhibited by SHE Conclusion : The results suggest that SHE has dose-dependant anti-oxidant ability, and has anti-allergic and anti-inflammatory effects through the suppression of $NF-{\kappa}B$ activation and the inhibition of Th 2 cell differentiation.

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Effect of pulse-wave factors in Middle Aged Women by Mountain Cultivated Ginseng Pharmacopuncture Original Articles (산삼 약침이 정상 중년여성의 맥파요인에 미치는 영향)

  • Park, Sang-Wook;Kim, Yi-Soon;Hwang, Won-Deok;Kim, Gyeong-Cheol
    • Journal of Pharmacopuncture
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    • v.14 no.1
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    • pp.35-49
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    • 2011
  • Objectives: The aim of this experiment is to know about Effect of pulse-wave factors in Middle Aged Women by Mountain Cultivated Ginseng Pharmacopuncture. Methods: First 20 Middle Aged women are diagnosed by pulse diagnosis, and then Mountain Cultivated Ginseng Pharmacopuncture(1 injection 20cc) were injected. 30 minutes later, pulse diagnosis again performed. As a result, method of one-group pretest-posttes design were used for evaluation. Results: T(Total pulse cycle) time statistically significant increased on both left and right chon, kwan, cheok. T4 time statistically significant increased on both left and right chon, kwan, cheok. T4-T1/T indexs except left cheokmaek, Right cheokmaek observation area decreased significantly in four sites. Wm(indicating high pressure retention time) indexs increased significantly in the five sites were observed except right chon maek. Conclusions: Effect of pulse-wave factors in Middle Aged Women by Mountain Cultivated Ginseng Pharmacopuncture increased T, T4, Wm and decreased T4-T1/T indexs. The results of this experiment, Mountain Cultivated Ginseng Pharmacopuncture induced to increase the Pulse-wave's stability and strength.

Predicting idiopathic pulmonary fibrosis (IPF) disease in patients using machine approaches

  • Ali, Sikandar;Hussain, Ali;Kim, Hee-Cheol
    • Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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    • 2021.05a
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    • pp.144-146
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    • 2021
  • Idiopathic pulmonary fibrosis (IPF) is one of the most dreadful lung diseases which effects the performance of the lung unpredictably. There is no any authentic natural history discovered yet pertaining to this disease and it has been very difficult for the physicians to diagnosis this disease. With the advent of Artificial intelligent and its related technologies this task has become a little bit easier. The aim of this paper is to develop and to explore the machine learning models for the prediction and diagnosis of this mysterious disease. For our study, we got IPF dataset from Haeundae Paik hospital consisting of 2425 patients. This dataset consists of 502 features. We applied different data preprocessing techniques for data cleaning while making the data fit for the machine learning implementation. After the preprocessing of the data, 18 features were selected for the experiment. In our experiment, we used different machine learning classifiers i.e., Multilayer perceptron (MLP), Support vector machine (SVM), and Random forest (RF). we compared the performance of each classifier. The experimental results showed that MLP outperformed all other compared models with 91.24% accuracy.

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Indoor Noise limits of Apartment Houses for Road Traffic Noise by Psycho-acoustic Experiment (청감실험을 통한 도로교통소음에 대한 공동주택 내부소음 기준설정 연구)

  • Lee, Ju-Yeob;Kim, Hang;Song, Min-Jeong;Jang, Gil-Soo;Kim, Sun-Woo
    • Proceedings of the Korean Society for Noise and Vibration Engineering Conference
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    • 2005.05a
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    • pp.83-86
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    • 2005
  • The aim of this study is to establish the indoor noise limits of apartment houses for mad traffic noise. To achieve this goal, psycho-acoustic experiments were carried out with the mad traffic sound sources modulated by the transmission loss characteristics of the external windows. As a result of this study, followings are suggested. 1) On correlation between dose level and psycho-acoustical response, the initial level of negative feeling is located on $40.1{\sim}40.6$ Leq dB(A). 2) On the degree of satisfaction to road traffic noise, near 35% Point being same dissatisfaction degree is to be assumed $40{\sim}41$ dB(A) of indoor noise level presented into three vocabulary. It is suggested to be reasonable level of 40 dB(A) on the indoor noise limits for intruding road traffic noise, and it is appropriate to be the 5dB level difference between grades.

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Identification on a Local Wall Thinning by Flow Acceleration Corrosion Inside Tee of Carbon Steel Pipe (탄소강 배관 티에서의 유동가속부식으로 인한 감육 현상 규명)

  • Kim, Kyung-Hoon;Lee, Sang-Kyu;Kang, Deok-Won
    • Journal of ILASS-Korea
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    • v.16 no.2
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    • pp.82-89
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    • 2011
  • When pipe components made of carbon steel in nuclear, fossil, and industry plants are exposed to flowing fluid, wall thinning caused by FAC(flow accelerated corrosion) can be generated and eventually ruptured at the position of pressure boundary. The aim of this study is to identify the locations at which local wall thinning occurs and to determine the turbulence coefficient related to local wall thinning. Experiment and numerical analyses for the tee sections of down scaled piping components were performed and the results were compared. In particular, flow visualization experiment which was used alkali metallic salt was performed to find actual location of local wall thinning inside tee components. In order to determine the relationship between turbulence coefficients and local wall thinning, numerical analyses were performed for tee components in the main feedwater systems. The turbulence coefficients based on the numerical analyses were compared with the local wall thinning based on the measured data. From the comparison of the results, the vertical flow velocity component(Vr) flowing to the wall after separating in the wall due to the geometrical configuration and colliding with the wall directly at an angle of some degree was analogous to the configuration of local wall thinning.

HRV Analysis for Aged Using Visual Stimulus Protocol (시각 자극에 의한 노인 HRV 해석)

  • Lee Chung-Ki;Lee Byung-Chae;Jeong Kee-Sam;Kim Nam-Hyun;Yoo Sun-Kook
    • The Transactions of the Korean Institute of Electrical Engineers D
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    • v.54 no.5
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    • pp.330-337
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    • 2005
  • The ratio of aged class has been increasing gradually not only in Korea, but also in the world since several years ago. As a result, many unexpected social problems started to now. The burden charged to this society is to solve those problems; how to take care of that aged people, how to offer jobs to them, etc. It means that the study about the aged class should be done soon. Due to that need, this thesis is wrote out. The aim of this thesis is to detect the emotion of aged people and establish a certain algorithm for detecting it. In the whole process of experiment and analysis, I used HRV(Heart Rate Variability) data since the heart is a representative which is controlled by the ANS(autonomic nervous system), and the ANS reflects the changes in emotion. After stimulating the aged people with the authorized pictures which induce different emotions each. 1 measured HRV of those aged. The HRV data is then analyzed in the two domain area, time and frequency. 1 guessed that the result would show some certain differences according to the pictures and it was shown from the experiment. Seeing the result, HRV was changed by what the aged felt looking at the pictures. Then it also means that visual stimulation influence on the has of the aged people.

ASUSD nuclear data sensitivity and uncertainty program package: Validation on fusion and fission benchmark experiments

  • Kos, Bor;Cufar, Aljaz;Kodeli, Ivan A.
    • Nuclear Engineering and Technology
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    • v.53 no.7
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    • pp.2151-2161
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    • 2021
  • Nuclear data (ND) sensitivity and uncertainty (S/U) quantification in shielding applications is performed using deterministic and probabilistic approaches. In this paper the validation of the newly developed deterministic program package ASUSD (ADVANTG + SUSD3D) is presented. ASUSD was developed with the aim of automating the process of ND S/U while retaining the computational efficiency of the deterministic approach to ND S/U analysis. The paper includes a detailed description of each of the programs contained within ASUSD, the computational workflow and validation results. ASUSD was validated on two shielding benchmark experiments from the Shielding Integral Benchmark Archive and Database (SINBAD) - the fission relevant ASPIS Iron 88 experiment and the fusion relevant Frascati Neutron Generator (FNG) Helium Cooled Pebble Bed (HCPB) Test Blanket Module (TBM) mock-up experiment. The validation process was performed in two stages. Firstly, the Denovo discrete ordinates transport solver was validated as a standalone solver. Secondly, the ASUSD program package as a whole was validated as a ND S/U analysis tool. Both stages of the validation process yielded excellent results, with a maximum difference of 17% in final uncertainties due to ND between ASUSD and the stochastic ND S/U approach. Based on these results, ASUSD has proven to be a user friendly and computationally efficient tool for deterministic ND S/U analysis of shielding geometries.

Temperature Control using Peltier Element by PWM Method

  • Pang, Du-Yeol;Jeon, Won-Suk;Choi, Kwang-Hoon;Kwon, Tae-Kyu;Kim, Nam-Gyun;Lee, Seong-Cheol
    • 제어로봇시스템학회:학술대회논문집
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    • 2005.06a
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    • pp.1400-1404
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    • 2005
  • This paper presents the temperature control of aluminum plate by using Peltier element. Peltier effect is heat pumping phenomena by electric energy as one of the thermoelectric effect. So if current is charged to Peltier element, it absorbs heat from low temperature side and emits heat to high temperature side. In this experiment, Peltier element is used to control the temperature of small aluminum plate with current control and operating cooling fan only while cooling duration. Operating cooling fan only while cooling duration is proper to get more rapid heating and cooling duration. As a result of experiment, it takes about 100sec period to repeating temperature between $35^{\circ}C$ and $70^{\circ}C$ and about 80sec from $40^{\circ}C$ to $70^{\circ}C$ in ambient air temperature $25^{\circ}C$ and while operating cooling fan only in cooling duration. Future aim is to apply this temperature control method in actuating SMHA(special metal hydride actuator) which is applicable in Siver project acting in low frequency range by using Peltier element for heating and cooling.

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Experimental Study of Thermo-electric material using Lithium-Ammonia$(Li(NH_3)_n)$ Solution (리튬-암모니아 $(Li(NH_3)_n)$ 용액을 이용한 열전기적 특성 실험)

  • Park, Han-Woo;Kim, Ji-Beom;Jeon, Joon-Hyeon
    • Korean Chemical Engineering Research
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    • v.49 no.2
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    • pp.263-270
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    • 2011
  • The aim of this paper is, through the experiment of Lithium-Ammonia solutions $(Li(NH_3)_n)$, to analyze and verify a thermoelectric-conversion property at near Ammonia-boiling point ($-40^{\circ}C$). The experiment results show that the solutions with 0.58 MPM~1.87 MPM generate thermoelectric power at temperature difference $({\Delta}T=0{\sim}15^{\circ}C)$ where Current is constantly proportional to Voltage. This paper provides a new insight into the development of a thermoelectric material.

A Review on the Job Stress Measurements in Nuclear Power Plant Workers for Human Error Prevention

  • Kim, Seon Soo;Luo, Meiling;Oh, Yeon Ju;Lee, Yong Hee
    • Journal of the Ergonomics Society of Korea
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    • v.32 no.1
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    • pp.47-58
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    • 2013
  • Objective: The aim of this study is to review the job stress measurement for applying in nuclear power plants(NPPs). Background: The standard and guideline to evaluate and manage the job stress is insufficient in NPPs. Although job stress might have a negative effect on task performance particularly it can be related with human error in NPPs. Method/Results: This paper considered the objective and subjective stress measurements. One of the questionnaire(Korean Occupational Stress Scale) and the experiment method was investigated to apply in NPPs. KOSS was analyzed about the inter item consistency and correlation with the workload, and relative importance. In the objective evaluation considered the experiment method for the physical and mental job stress and analyzed from the phased point of view. Conclusion/Application: The measurement and criteria to evaluate job stress for operators must be complemented on the job characters and environments in NPPs. This study may support to confirm and manage the job stress in NPPs. The study of more specific methodology on job stress in NPPs is required on the basis of this paper.