• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.25 no.3
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• pp.88-96
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• 2012

Objectives : We investigated the skin properties on the periorbital region and cheek of Korean female according to age pattern by 7year based on Sang Go Cheun Jin Ron (上古天眞論) in So Moon (素問,) Methods : 49 Korean females, aged 21-56 years ($39.54{\pm}10.04$ years) were participated in this study. We measured the skin properties of periorbital region and cheek with SkinTouch (Amorepacific, Korea). Skin moisture, sebum, elasticity, lightness, roughness, area of wrinkle, depth of wrinkle were assessed. Results : Differences were noticed depending on the site and age. The level of moisture was higher on the eyelid than crow's feet. The level of lightness and elasticity were lower on the periorbital region than cheek. Skin lightness was highest on group1(under 28y) and lowest on group5(over 49y). Skin roughness was highest on group1(under 28y) and lowest on group4(over 42y under 49y). The level of wrinkle are was lowest on group1(under 28y) and highest on group 5(over49y). The level of wrinkle depth was lowest on group1(under 28y) and highest on group 4(over 42y under 49y). Conclusion : Unique aging pattern by 7 years of female is reflected to diverse skin properties of eyes. It can be possible to apply the theory on Sang Go Cheun Jin Ron (上古天眞論) to practical use in dermatology and cosmetic.

• Composites Research
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• v.22 no.5
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• pp.37-42
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• 2009

Thermal analysis properties and chemical structure of carbon fiber/epoxy composites under environmental exposure were examined using an accelerated aging tester which can simulate real weather conditions such as temperature, moisture and ultraviolet. The composite specimens were exposed to combined environmental factors up to 3000 hours. Thermal analysis properties and chemical structure of the composites were evaluated with various exposure times through Modulated DSC and FTIR. According to the results of Modulated DSC, the glass transition temperature increased as exposure time increased due to the formation of network structures in the composites. Also endotherm peaks of enthalpy relaxation related to physical aging that can affect the properties of the composites were observed as exposure time increased. From the results of FTIR, it was found that the location of the peaks was little affected by exposure time, but the intensity of the peaks slightly decreased as exposure time increased due to the curing reaction in the epoxy group.

• The Korean Journal of Physiology and Pharmacology
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• v.21 no.2
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• pp.205-213
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• 2017

Quercetin, a plant-derived flavonoid found in fruits, vegetables and tea, has been known to possess bioactive properties such as anti-oxidant, anti-inflammatory and anti-cancer. In this study, anti-cancer effect of quercetin and its underlying mechanisms in triple-negative breast cancer cells was investigated. MTT assay showed that quercetin reduced breast cancer cell viability in a time and dose dependent manner. For this, quercetin not only increased cell apoptosis but also inhibited cell cycle progression. Moreover, quercetin increased FasL mRNA expression and p51, p21 and GADD45 signaling activities. We also observed that quercetin induced protein level, transcriptional activity and nuclear translocation of Foxo3a. Knockdown of Foxo3a caused significant reduction in the effect of quercetin on cell apoptosis and cell cycle arrest. In addition, treatment of JNK inhibitor (SP 600125) abolished quercetin-stimulated Foxo3a activity, suggesting JNK as a possible upstream signaling in regulation of Foxo3a activity. Knockdown of Foxo3a and inhibition of JNK activity reduced the signaling activities of p53, p21 and GADD45, triggered by quercetin. Taken together, our study suggests that quercetin induces apoptosis and cell cycle arrest via modification of Foxo3a signaling in triple-negative breast cancer cells.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.10 no.6
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• pp.1175-1179
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• 2009

We analyze voltage characteristics of charged particle type display according to particle layers and cell gap between two electrodes and ascertain the aging effects by measuring the response time of particles with and without aging process. The threshold/driving/breakdown voltage is proportional to layers of charged particles and cell gap and the response time at driving voltage is faster than that of threshold and breakdown voltage because of different q/m of color and black particles. The analysis of response time is a method of estimation of optical characteristics, driving voltage and particle lumping and these results are promoted by aging process. We use the laser and photodiode to measure response time and optical properties. It has not been studied and reported to analyze the relationship of response time, threshold/driving/breakdown voltage, lumping phenomena, cell gap, and aging process for charged particle type display.

• Proceedings of the KWS Conference
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• 2002.10a
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• pp.59-64
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• 2002

Effects of the aging treatments on the microstructure and strength of heat affected zone(HAZ) in the welds of a age-hardened Al-Mg-Si alloy, 5N01-T5, were investigated. The base metal aging treatments before MIG welding were conducted at 423K to 473K for 28.8ks Post weld heat treatment(PWHT) to recover the HAZ strength was performed at 448K for 28.8ks. Microstructure observations, hardness measurements and tensile tests were conducted to study properties of the MIG weld joints. The position of the softest region in HAZ where the hardness insufficiently recovered after natural aging and PWHT was at a distance of approximately 15mm from the center of the fusion zone. Hardness of the softest regions after natural aging and PWHT decreased with increase in the base metal aging temperature. TEM observation clarified that strengthening ${\beta}$"(Mg$_2$Si) precipitates and coarse ${\beta}$′ precipitates affected the hardnes of HAZ. Incomplete recover of hardness in HAZ after PWHT was caused by the precipitating of non-hardening ${\beta}$′ phase during the weld thermal cycle. In order to examine the effects of weldheat input and welding speed, the laser weld joints were also investigated and compared with the MIG weld ones. Laser welding had the narrower width of the softened regions in HAZ compared with MIG welding. The hardness of the softest regions of the laser welds after PWHT was higher than that of the MIG welds. Quantitative relations between hardness of the softest region and base metal aging temperature were obtained for both welding processes. Accordingly, the equations to estimate the strength of the weld joints after PWHT with varying base metal temperatures were proposed for MIG welding and laser welding.

• Asian-Australasian Journal of Animal Sciences
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• v.30 no.12
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• pp.1733-1738
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• 2017

Objective: Different dry-aging methods [traditional dry-aging (TD), simplified dry-aging (SD), and SD in an aging bag (SDB)] were compared to investigate the possible use of SD and/or SDB in practical situations. Methods: Sirloins from 48 Hanwoo cows were frozen (Control, 2 days postmortem) or dry-aged for 28 days using the different aging methods and analyzed for chemical composition, total aerobic bacterial count, shear force, inosine 5′-monophosphate (IMP) and free amino acid content, and sensory properties. Results: The difference in chemical composition, total aerobic bacterial count, shear force, IMP, and total free amino acid content were negligible among the 3 dry-aged groups. The SD and SDB showed statistically similar tenderness, flavor, and overall acceptability relative to TD. However, SDB had a relatively higher saleable yield. Conclusion: Both SD and SDB can successfully substitute for TD. However, SDB would be the best option for simplified dry-aging of low-marbled beef with a relatively high saleable yield.

• Journal of Animal Science and Technology
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• v.63 no.5
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• pp.1169-1181
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• 2021

We investigated the comparative physicochemical attributes, oxidative stability, and microbial characteristics of 28 days dry-aged meat in between boneless sirloin (gluteus medius) and bone-in T-bone steaks (infraspinatus) muscles from Korean Native Hanwoo Steer (KNHS). Results reveal that regardless of the muscles, dry-aging increased protein content and water-holding capacity (WHC) (p < 0.05). Meat from infraspinatus-aged muscle led to darker meat with higher pH values than un-aged meat (p < 0.05). However, fat content, CIE a^*, and CIE b^* remained unchanged in both muscles at aging. At aged meat, thiobarbituric acid reactive substances (TBARS) values from bone-in infraspinatus muscle was 2.5-fold higher than boneless gluteus medius muscle (p < 0.05). Dry-aging led to an increase in the contents of total unsaturated fatty acids (UFAs), monounsaturated fatty acids (MUFAs), and UFA/saturated fatty acids (SFA) in both muscles (p < 0.05). Furthermore, gluteus medius aged muscle concentrated with olic acid (C18:1) compared to infraspinatus aged muscle. Irrespective of the muscles, dry-aging enhanced the total free amino acids (FAAs) as well as tasty, and bitter amino acid contents whereas decreased the tasty/bitter amino acids (p < 0.05). Aromatic amino acid, tryptophan that converted to serotonin was 2-fold higher in boneless gluteus medius muscle than bone-in infraspinatus muscle at pre and post aging processes (p < 0.05). Aged Infraspinatus muscle increased total bacteria (p < 0.05) while no salmonella spp. was detected in both muscles. Taken together, our study confirms that 28 days dry-aging profiling the quality characteristics of boneless sirloin (gluteus medius) and bone-in T-bone steaks (infraspinatus) distinctly while gluteus medius aged steak performs better owing to oxidative stability and functional compounds than infraspinatus aged steak.

• Food Science and Biotechnology
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• v.17 no.1
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• pp.20-25
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• 2008

Effects of commercial and lab-generated gellan gums on the textural properties, structure, and aging of wheat and maize starch gels were investigated using a rapid visco-analyzer (RVA), rheometer, scanning electron microscope (SEM), and X-ray diffractometer. Gellan and guar gums increased the peak and final viscosities, but xanthan gum and gum arabic reduced them. The maize starch had higher breakdown viscosity than the wheat starch, regardless of the type of gum. The hardness of all starch gels increased during storage, but their cohesiveness and springiness decreased. The degree of the gel hardness showed higher in maize starch than in wheat starch and the effect of gum addition had a difference with gum type. The wheat starch-guar and -gellan gum mixed gels showed higher elasticity and cohesiveness after storage. The starch-gellan gum mixed gels had dense and stable network structures, and were well maintained even after 7 days of storage. Most of the gums had anti-aging effect on X-ray diffraction pattern of starch gels.

• Journal of the Korean institute of surface engineering
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• v.42 no.5
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• pp.246-249
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• 2009

Cu-Ti alloys with titanium in the range of 0.5-6.0 wt% were developed to evaluate the effect of the titanium content and heat treatment on microstructure, hardness, and electrical conductivity. The hardness of the Ti-added copper alloys generally increased with the increase in titanium content and hardening was effective up to the 2.5 wt%-Ti addition. Microstructural examination showed that the second phase of $Cu_4Ti$ started to precipitate out from the 3.0 wt% Ti-addition, and the precipitate size and volume fraction increased with further Ti addition. Aging of the present Cu-Ti alloys at $450^{\circ}C$ for 1 h increased the hardness; however, the further aging up to 10 h did not much change the hardness. In the present study, it was inferred that in optimal Ti addition and aging condition Cu-Ti alloy could have the hardness and electrical conductivity values which are comparable to those of commercial Cu-Be alloy.

• Korean Journal of Materials Research
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• v.17 no.12
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• pp.648-653
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• 2007

Plasma electrolytic oxidation (PEO) treatment was performed on cast Mg-6 wt%Al alloy solution-treated at 693K for 16h and aged at 498K. The surface roughness, thickness, micro-hardness, wear and corrosion properties of coatings on solution-treated and aged Mg-6 wt%Al alloy were investigated. The coatings on aged Mg-6 wt%Al alloy had thinner layer and lower micro-hardness and wear resistance than the solution-treated Mg-6 wt%Al alloy. As the aging time increased, the thickness of coatings decreased while the surface roughness was almost no changed. In addition, the micro-hardness and wear property of coatings decreased with increasing the aging time unlike the uncoated Mg-6 wt%Al alloy showing the peak micro-hardness and the best wear property after aging for 16 h. However, the coatings on Mg-6 wt%Al alloy peak-aged for 16h revealed the best corrosion resistance in 3.5% NaCl solution, which was explained based on the microstructural characteristics.