• The Korean Journal of Archival Studies
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• no.72
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• pp.205-239
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• 2022

Park Yong-gil's personal letter 'To You' collection is a valuable historical document that contains aspects of modern and contemporary Korea, managed by the Late Spring Moon Ik-Hwan Memorial Foundation. These letters were written for about 10 years and 3 months, and there are currently about 2,304 letters left, and support is needed to secure social feasibility for long-term preservation of historical materials and to establish a stable record management system. The purpose of this article is to introduce Park Yong-gil's letter, which has not been introduced in earnest, to the archival community, and to comprehensively review the whole story and examine the tasks. To this end, the meaning of the letter in Park Yong-gil's personal life was examined, and the value of this letter was particularly highlighted in terms of being a letter written as a part of Okbaraji. And by investigating and analyzing the status of the archives, the internal and external characteristics of the letter were comprehensively analyzed. The characteristics of Park Yong-gil's letter identified as a result of the study are that it is a letter sent to one person, and it is accumulated with a considerable amount and aggregation. In particular, it is expected to have a diverse user base in that it is easy to empathize with because it contains the familiar subject matter of letters and the stories of contemporaries, and contains a variety of informational values about contemporary events and people. Based on these historical and cultural values and various useful values of the letter 'To you', various research and development of services should be made in the future.

• Journal of Life Science
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• v.32 no.1
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• pp.56-62
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• 2022

This study was investigated to evaluate the potential of Stewartia koreana Nakai as an oral healthcare material. The inhibitory effects of extracts on the biofilm formation and fimbriae genes expression of Porphyromonas gingivalis were determined by minimal inhibitory concentrations (MIC), biofilm biomass staining, SEM, and qRT-PCR analysis. The S. koreana Nakai branch was extracted into 70% ethanol, and bacteriostatic MIC of extracts against P. gingivalis were 0.6 mg/ml. In P. gingivalis cultures treated with 0.2-2.0 mg/ml of extract, biofilm production rate was significantly decreased in a concentration-dependent manner. The morphology of treated and untreated samples was observed by SEM, and cell aggregation and biofilm were only observed in those treated with extract. Subsequently, qRT-PCR analysis showed that the mRNA expression on fimbriae genes fimA and fimB was suppressed in a concentration-dependent manner. Based on these results, it can be suggested that S. koreana branch extract has the potential to be used as naturally derived oral healthcare material because of its bacteriostatic action and inhibition of P. gingivalis biofilm formation.

• The Transactions of the Korea Information Processing Society
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• v.5 no.12
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• pp.3025-3035
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• 1998

In this paper, we describe the design and implementationof COIRS COncept,based Image Retricval System). It differs from extant content-based image retrieval systems in that it enables users to query based on concepts- it allows users to get images concepmally relevant. A concept is basically an aggregation of promitive objects in an image. For such a cencept based image retrieval functionality. COIRS aglopts an image descriptor called triple and includes a triple thesaurus used for capturing concepts. There are four facilities in COIRS: a visual image indeses a triple thesaurus, an inverted fiel, and a user query interface. The visnal image indeser facilitates object laeling and the percification of positionof objects. It is an assistant tool designed to minimize manual work when indexing images. The thesarrus captires the concepts by analyzing triples, thereby extracting image semantics. The triples are then for formalating queries as well as indexing images. The user query interiare enables users to formulate...

• Journal of Applied Biological Chemistry
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• v.65 no.4
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• pp.239-245
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• 2022

Although normal activation of platelets is important in the process of hemostasis, excessive or abnormal activation of platelets can lead to cardiovascular diseases. Therefore, the discovery of novel substances capable of regulating or inhibiting platelet activation may be helpful in the prevention and treatment of cardiovascular diseases. Artemether is a derivative of artemisinin, known as an active ingredient of Artemisia annua, which has been reported to be effective in treating malaria, and is known to function through antioxidant and metabolic enzyme inhibition. However, the role of artemether in platelet activation and aggregation and the mechanism of action of artemether in collagen-induced human platelets are not known until now. This study investigated the effects of artemether on platelet activation and thrombus formation induced by collagen. As a result, cAMP level was significantly increased by artemether, and VASP and IP3R, substrates of cAMP-dependent kinase, were phosphorylated. IP3R phosphorylation by Artemether inhibited Ca²⁺ recruitment into the cytoplasm, and phosphorylated VASP inhibited fibrinogen binding by inactivating αIIb/β3 located on the platelet membrane. Consequently, artemether inhibited thrombin-induced fibrin clot formation. Therefore, we propose that artemether can act as an effective prophylactic and therapeutic agent for cardiovascular diseases caused by excessive platelet activation and thrombus formation.

• Journal of Korean Philosophical Society
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• no.93
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• pp.175-199
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• 2011

The development of contemporary utilitarianism can be taken to be an aggregation of many attempts to surmount the limitations of classical utilitarianism. In these attempts, contemporary utilitarianism suggests alternatives to 'hedonism' and 'act-utilitarianism' which have been regarded as the common essential elements of classical utilitarianism. First, contemporary utilitarianism replaces the concept of 'happiness' or 'pleasure' in the classical utilitarianism with that of 'desire-fulfillment' or 'preference-satisfaction'. Through this replacement, contemporary utilitarianism tries to avoid the skeptical challenge to the mental state theory inherent in the classical concept of utility, and also to provide a more extensive conception of utility for a more satisfactory explanation of human welfare. Second, the development of rule-utilitarian theories which can evade the criticisms about 'counter-productivity' and 'counter-intuitiveness' of act-utilitarianism constitutes another important trend of contemporary utilitarianism. Characteristically, rule-utilitarian theories developed in the contemporary utilitarianism grope for some utilitarian system that can embrace socially accepted general norms. Lastly, contemporary utilitarianism responds to the criticisms related the problem of justice by reinterpreting the first principle of utilitarianism. This reinterpretation is an attempt to explain the egalitarian basis of utilitarianism through Bentham's dictum 'everyone counts for one, none for more than one'. It seems true that many influential criticisms in the latter half of 20th century cast a deep shadow on utilitarianism. But through the above attempt, contemporary utilitarianism proceeds to a better explanation of human welfare.

• Clean Technology
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• v.16 no.2
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• pp.124-131
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• 2010

Effects of $Ca(OH)_2$ concentration (0.16~0.64 wt%), surfactant concentration (2~16 wt%), total volumetric flow rate (3~6 L/min) and $CO_2$ volume fraction $(0.3{\sim}0.6)$ on morphology, crystal structure, mean particle diameter, aggregation and specific surface area of the precipitated $CaCO_3$ were investigated in the slurry bubble column reactor. Experiments were carried out in acrylic reactor ($0.11\;m-ID{\times}1.0\;m-high$) with a internal tube ($0.04\;m-ID{\times}1.0\;m-high$h). The reaction time of $CaCO_3$ synthesis decreased with adding Dispex N40 of the anionic surfactant. The reaction rate of $Ca(OH)_2$ increased with increasing the volumetric flow rate of $CO_2$. From SEM images, the single crystal of $CaCO_3$ increased with increasing the reaction rate in the saturated concentration of $Ca(OH)_2$ (0.16 wt %) and the concentration of Dispex N40 (2 wt%). The mean particle size of $CaCO_3$ varied with adding Dispex N40. In addition, the specific surface area of $CaCO_3$ increased with adding of surfactant (2 wt%) from $35m^2/g$ to $44m^2/g$ at the volumetric flow rate of $CO_2$ (0.9 L/min) and the concentration of $Ca(OH)_2$(0.64 wt %).

• Journal of the Society of Cosmetic Scientists of Korea
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• v.49 no.1
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• pp.17-27
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• 2023

A study was performed to increase skin permeation of tocopheryl acetate, an oil-soluble component among tocopheryl acetate, salicylic acid, and niacinamide, which are the active ingredients of the anti-hair loss toner. As a method of transparently solubilizing tocopheryl acetate while containing salicyl acid and niacinamide, we used a swollen micelle structure that increased the size of the micelle formed by the aggregation of surfactants. The prepared swollen micelle solution contains three kinds of active ingredients, and poloxamer 407 and octyldodeceth-16 were used as surfactants to increase transparent properties and stability. In addition, isostearic acid was used as a co-surfactant to increase the size of micelles. To evaluate the physical properties of the prepared swollen micelles, turbidity at room temperature (25 ℃) was measured. The Franz diffusion cell method was used to evaluate the skin permeation rate of tocopheryl acetate among the hair-loss prevention components contained in swollen micelles. After 24 h, tocopheryl acetate showed a 6-fold improvement in skin permeation compared to the control group. Therefore, it can be seen that the swollen micelles developed in this study can be applied to hair-loss prevention products or solubilized formulations of various functional cosmetics.

• Journal of the Economic Geographical Society of Korea
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• v.26 no.1
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• pp.1-22
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• 2023

This study proposes an integrated use of region and industry as a way to classify firms' innovation activities by type. Existing studies have used the method of determining innovative activities according to the components of the technological regimes and aggregating them by industry classification, but this method cannot fully reflect the heterogeneity within industries in an increasingly sophisticated innovation environment. Therefore, this study divides firms by region and industry and conducts a cluster analysis on the proportion of innovative activities by the components of the technological regimes to derive a total of four innovation types. Using the 2016 Korean Innovation Survey to classify innovation types in the manufacturing industry, we found that innovation activities are concentrated in Seoul, Busan, Incheon, and Chungnam/ Sejong/ Daejeon area, with different deviations by region and industry. The results of the aggregation of industrial innovation activities, weighted by corporate activity by region, show that the level of innovation activity in some manufacturing industries, such as petrochemicals, manufacturing of medical, precision and optical instruments, watches and clocks, is high, but the level of innovation in other sectors within the manufacturing industry is generally low.

• Asia-pacific Journal of Multimedia Services Convergent with Art, Humanities, and Sociology
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• v.8 no.5
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• pp.303-314
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• 2018

In the past few years, government agencies and corporations have succumbed to stealthy, tailored cyberattacks designed to exploit vulnerabilities, disrupt operations and steal valuable information. Security Information and Event Management (SIEM) is useful tool for cyberattacks. SIEM solutions are available in the market but they are too expensive and difficult to use. Then we implemented basic SIEM functions to research and development for future security solutions. We focus on collection, aggregation and analysis of real-time logs from host. This tool allows parsing and search of log data for forensics. Beyond just log management it uses intrusion detection and prioritize of security events inform and support alerting to user. We select Elastic Stack to process and visualization of these security informations. Elastic Stack is a very useful tool for finding information from large data, identifying correlations and creating rich visualizations for monitoring. We suggested using vulnerability check results on our SIEM. We have attacked to the host and got real time user activity for monitoring, alerting and security auditing based this security information management.

• Resources Recycling
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• v.32 no.3
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• pp.18-25
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• 2023

Sericite was ground with or without additives (LiNO₃ or TiO₂) using a planetary mill. The resultant ground products included the average particle size of 2-3 ㎛ (sericite only or sericite+LiNO₃) and 0.5-0.6 ㎛ (sericite+TiO₂) were obtained within 10 minutes of grinding time. respectively. In the grinding of the sericite without any addictive, the particle size initially decreased, but, as grinding time elapsed thereafter, agglomerates were formed and D50 increased over 10 ㎛. In contrast, when the additive was added, the particle size decreased as the grinding time elapsed and any aggregation was relatively not noticeable, compared with the grinding of the sericite only. As a result of measuring the zeta potential for the raw or the ground samples, variation of the zeta potential values according to pH at the early stage of the grinding with the addictives was gentler than that at the final stage of grinding, which showed the relatively similar trend to the pH-zeta potential correlation in grinding of raw sericite. In addition, as a result of the disintegration experiment through ultrasonic excitation, D50 decreased rapidly only until the disintegration time of about 50 minutes.