• Journal of the korean academy of Pediatric Dentistry
• /
• v.45 no.4
• /
• pp.455-463
• /
• 2018

The purpose of this study was to evaluate the effect of the intracanal medicaments on the push-out bond strength of the calcium silicate-based materials. Forty extracted single-root human mandibular premolars were sectioned below cementoenamel junction. Standardized root canal dimension was obtained with a parallel post drill. The specimens were randomly divided into a control group (no medicament), and experimental groups received medicaments with either CH (calcium hydroxide), DAP (double antibiotic paste; a mixture of ciprofloxacin and metronidazole), or TAP (triple antibiotic paste; a mixture of minocycline, ciprofloxacin and metronidazole). Following removal of medicaments with irrigation, roots were cut into sections with 1-mm-thickness. Thereafter, calcium silicate-based materials are applied to the specimens : (i) ProRoot MTA$^{(R)}$ and (ii) Biodentine$^{(R)}$. A push-out bond strength was measured and each specimen was examined to evaluate failure mode. Intracanal medication using CH significantly increased the bond strength to the root dentin. But there are no significant differences on the bond strength of ProRoot MTA$^{(R)}$ or Biodentine$^{(R)}$ among TAP, DAP and control groups. The dislodgement resistance of Biodentine$^{(R)}$ from root dentin was significantly higher than that of ProRoot MTA$^{(R)}$ regardless of the type of intracanal medicaments.

• Journal of the Korean Society of Marine Environment & Safety
• /
• v.19 no.5
• /
• pp.417-429
• /
• 2013

The current study attempted to assess the environmental value of Geum-river estuary for rational management decision-making. To investigate the comprehensive properties of the Geum-river estuary, we applied the contingent valuation method based on multi-attribute utility theory. We surveyed a randomly selected sample of 400 and 600 households of the Geum-river estuary-neighboring area (Jeollabuk-do, Chungcheongnam-do), and other nation-wide large districts (except Jeollabuk-do, Chungcheongnam-do, and Jeju-do), respectively, and carried out person-to-person interviews with subjects on their willingness-to-pay for the estuary conservation and management program. Respondents, overall, accepted the contingent market system and were willing to contribute a significant amount, that is 1,497 won for the residents from the Geum-river estuary-neighboring area and 4,343 won for the residents from other nation-wide large districts on average, per household per year. These results implied that there were large difference between the two groups. The aggregate values of the Geum-river estuary for the estuary-neighboring area and other nation-wide large districts amount to 2.13 and 70.15 billion won, respectively, per year. This quantitative value deduced from the current study, could be a useful baseline fact for any decision-making process particularly in the establishment of management policies for the Geum-river estuary.

• Macromolecular Research
• /
• v.12 no.1
• /
• pp.127-133
• /
• 2004

We have studied the surface micelle formation of polystyrene-b-poly(2-vinyl pyridine) (PS-b-P2VP) at the air-water interface. A series of four PS-b-P2VPs were synthesized by anionic polymerization, keeping the PS block length constant (28 kg/㏖) and varying the P2VP block length (1, 11, 28, or 59 kg/㏖). The surface pressure-area ($\pi$-A) isotherms were measured and the surface morphology was studied by atomic force microscopy (AFM) after Langmuir-Blodgett film deposition onto silicon wafers. At low surface pressure, the hydrophobic PS blocks aggregate to form pancake-like micelle cores and the hydrophilic P2VP block chains spread on the water surface to form a corona-like monolayer. The surface area occupied by a block copolymer is proportional to the molecular weight of the P2VP block and identical to the surface area occupied by a homo-P2VP. It indicates that the entire surface is covered by the P2VP monolayer and the PS micelle cores lie on the P2VP monolayer. As the surface pressure is increased, the $\pi$-A isotherm shows a transition region where the surface pressure does not change much with the film compression. In this transition region, which displays high compressibility, the P2VP blocks restructure from the monolayer and spread at the air-water interface. After the transition, the Langmuir film becomes much less compressible. In this high-surface-pressure regime, the PS cores cover practically the entire surface area, as observed by AFM and the limiting area of the film. All the diblock copolymers formed circular micelles, except for the block copolymer having a very short P2VP block (1 kg/㏖), which formed large, non-uniform PS aggregates. By mixing with the block copolymer having a longer P2VP block (11 kg/㏖), we observed rod-shaped micelles, which indicates that the morphology of the surfaces micelles can be controlled by adjusting the average composition of block copolymers.

• Molecules and Cells
• /
• v.41 no.5
• /
• pp.423-435
• /
• 2018

This investigation was aimed at working out the combined role of lncRNA H19, miR-29b and Wnt signaling in the development of colorectal cancer (CRC). In the aggregate, 185 CRC tissues and corresponding para-carcinoma tissues were gathered. The human CRC cell lines (i.e. HT29, HCT116, SW480 and SW620) and normal colorectal mucosa cell line (NCM460) were also purchased. Si-H19, si-NC, miR-29b-3p mimics, miR-29b-3p inhibitor, si-PGRN and negative control (NC) were, respectively, transfected into the CRC cells. Luciferase reporter plasmids were prepared to evaluate the transduction activity of $Wnt/{\beta}-catenin$ signaling pathway, and dual-luciferase reporter gene assay was arranged to confirm the targeted relationship between H19 and miR-29b-3p, as well as between miR-29b-3p and PGRN. Finally, the proliferative and invasive capacities of CRC cells were appraised through transwell, MTT and scratch assays. As a result, overexpressed H19 and down-expressed miR-29b-3p displayed close associations with the CRC patients' poor prognosis (P < 0.05). Besides, transfection with si-H19, miR-29b-3p mimic or si-PGRN were correlated with elevated E-cadherin expression, decreased snail and vimentin expressions, as well as less-motivated cell proliferation and cell metastasis (P < 0.05). Moreover, H19 was verified to directly target miR-29b-3p based on the luciferase reporter gene assay (P < 0.05), and miR-29b-3p also bound to PGRN in a direct manner (P < 0.05). Finally, addition of LiCl ($Wnt/{\beta}-catenin$ pathway activator) or XAV93920 ($Wnt/{\beta}-catenin$ pathway inhibitor) would cause remarkably altered E-cadherin, c-Myc, vimentin and snail expressions, as well as significantly changed transcriptional activity of ${\beta}-catenin/Tcf$ reporter plasmid (P < 0.05). In conclusion, the lncRNA H19/miR-29b-3p/PGRN/Wnt axis counted a great deal for seeking appropriate diagnostic biomarkers and treatment targets for CRC.

• Magazine of the Korea Concrete Institute
• /
• v.10 no.4
• /
• pp.153-161
• /
• 1998

Concrete structures has been deteriorated by and freezing the thawing due to temperature gap. This study was conducted to evaluate durability of concrete which are increasingly demanded recently. Therefore the research of durability must be executed for application of waste foundry sand concrete real structures. Concrete durability properties incorporating waste foundry sand was performed with the variable of W/C ratio. Sand/Waste foundry sand ratio and Air entrainment-Non air entrainment. Cylinder specimens were made and subjected to freezing and thawing cycle at -18$^{\circ}C$ and 4$^{\circ}C$. Dynamic modulus of elasticity were evaluated as F/T cycle increase. The results show that strength of concrete is increased the W/C ratio decrease, the Sand/Waste foundry sand ratio increases when the concrete contains AE agent and decreasing W/C ratio and AE concrete makes improved resistance of freezing and thawing improved. Especially, resistance of freezing and thawing is improved by Fine aggregate/Waste foundry sand ratio which is 50%, 25%, 0% in a row. Therefore it is turn out the waste foundry sand could be applied to concrete from the experiment.

• Journal of the Korea Concrete Institute
• /
• v.26 no.6
• /
• pp.731-739
• /
• 2014

This paper describes the evaluation of the impact performance of steel fiber-reinforced concrete based on high-velocity impact experiments using hard spherical balls. In this experimental study, panel specimens with panel thickness to ball diameter (h/d) ratios of 3.5 or less were tested with variables of steel fiber volume fraction, panel thickness, impact velocity, and aggregate size. Test results were compared with each other to evaluate the impact resistance. The results showed that the percentage of weight and surface loss decreased as the steel volume fraction increased. However, the penetration depth increased with up to steel fiber volume fraction of 1.5%. Particularly the results of specimens with 20 mm aggregates showed poorer performance than those with 8 mm aggregates. The results also confirmed that the impact performance prediction formulas are conservative with (h/d) ratios of 3.5 or less. Despite the conservative predictions, the modified NDRC formula and ACE formula predict the impact performance more consistently than the Hughes formula.

• Journal of the Korean Recycled Construction Resources Institute
• /
• v.3 no.2
• /
• pp.152-158
• /
• 2015

In order to investigate the feasibility of stone dust sludge as fine aggregate, an experimental study was performed on cement mortar with stone dust sludge. fresh mortar properties and strength with various stone dust sludge replacement ratios were estimated. the replacement ratio adopted in this study was 0, 10, 20, 30%. Flow, air content, and rheological properties were considered as properties of fresh mortar. Compressive strength and flexural tensile strength were measured for strength. The results are as follows. Higher amount of stone dust sludge caused reduction in slump and air content. In the rheological properties, both yield stress and plastic viscosity increased as stone dust sludge content increased up to 20% replacement ratio, but there were no remarkable difference between 20 and 30%. Yield stress increased drastically between 10 and 20%. Compressive and flexural tensile strength results indicated that the strength variation was not significant according to stone dust sludge content, but the strength gain in the early age by adding stone dust sludge was evident. the strength at the age of 28 days however did not show noticeable effect of adding stone dust sludge.

• Journal of the Korea Institute of Building Construction
• /
• v.17 no.3
• /
• pp.227-234
• /
• 2017

This research analyzes the properties of mortar following the rise in water-cement ratio and applicability as an eco-friendly construction supply by using the mudflats of a dredged arena as a substitute for aggregate. The results of a experiment of the flow showed that the flow value decreases as the amount of mudflats increases. A test for chloride content showed that the chloride content increases with the amount of mudflats. In the compression of specimen mixed with mudflat and the testing of tensile strength, the strength weakened as the addition ratio of mudflats rose. However, with 14-day strength as the standard, most specimen showed more strength than the plain, and 14-day strength was higher than 28-day strength. It appears to be experimental error in the mixing process from the viscosity and cohesion of mudflats, and it is considered that there will be a need for an experiment on mixing methods of mudflats in the future. The compressive strength of this research was the strongest with 70% in water-cement ratio, and the tensile strength was strongest with 80% in water-cement ratio. In the evaluation of surface analysis, 70% water-cement ratio, which is finest in strength, mixing, and compactness, was selected to analyze the roughness of the surface, and the results showed that the surface became smoother as the addition ratio of mudflats increases. In conclusion, it appears that 70% water-cement ratio is the optimal mixing ratio for mortar and 10 to 30% addition ratio of mudflats the optimal ratio. It also appears that the application of interior finishing material like bricks and tiles and interior plastering material using the mudflats are possible.

• Korean Journal of Construction Engineering and Management
• /
• v.19 no.4
• /
• pp.52-60
• /
• 2018

In the construction industry, attempts to evaluate the environmental impact of products through life cycle assessment (LCA) approach has been on the rise. However, the domestic construction industry needs to make rapid decisions due to limited budget and schedule, so it is difficult to carry out a review of the environmental load on all resources. The decision-making process requires information on the major influence factors that should be focused on to reduce environmental load. And this information should be quantified so that it can be linked to environmental impact assessment. In this study, the LCA results of road construction cases were analyzed to provide such information. As a result, diesel, ready-mixed concrete, urethane-based paint, aggregate, and asphalt concrete were found to be the main factors that generated 93.17% of the environmental load in the earthwork type of road project. The total environmental cost caused by these affecting factors when constructing 1 km of earthwork type of road project is 242 million won. The analysis also shows that a 10% reduction in the amount of ready-mixed and asphalt concretes can reduce carbon emissions by 5.02% and 2.28% while reducing environmental costs by 11 million won per kilometer. In order to reduce carbon emissions of the earthwork type of road project, it is necessary to actively develop and introduce new methods and eco-friendly materials to reduce the overall use of ready-mixed concrete and asphalt concrete.

• Journal of Environmental Policy
• /
• v.6 no.2
• /
• pp.1-25
• /
• 2007

This paper attempts to measure the environmental value of the Seomjin-River estuary that has been comparatively well conserved but is confronted with the threat of its development. Especially, in order to elicit the environmental values of its four attributes, contingent valuation method(CVM) based on multi-attribute utility theory is applied and the CVM survey was rigorously designed to comply with the guidelines. for best-practiced CVM studies. We surveyed a randomly selected sample of 300 and 350 households in the Seomjin-River estuary-neighboring area(Gwangyang, Sooncheon, Yeosu, Hadong, Namhae) and seven large cities(Seoul, Busan, Incheon, Daegu, Daejeon, Gwangju, Ulsan), respectively and asked respondents questions in person-to-person interviews about what they would willing to pay for the estuary conservation and management program. Respondents overall accepted the contingent market and were willing to contribute a significant amount(5,763 won in the Seomjin-River estuary-neighboring area and 1,883 won in seven large cities), on average, per household per year, which implies that there is a large difference between the two. The aggregate values of the Seomjin-River estuary in the estuary-neighboring area and seven large cities amount to 1.52 and 14.05 billion won, respectively, per year. The quantitative values can be utilized in planning and decision-making about development versus conservation of the estuary.