• Proceedings of the SCSK Conference
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• 2003.09a
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• pp.285-290
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• 2003

Living cells are continuously subject to all sorts of stress such as ultraviolet rays on skin cells. Tests made in various laboratories show that when young fibroblasts (Le. at the beginning of their proliferate life) were repeatedly put under stress at subletal doses, they acquired a phenotype similar to Senescence Induced Prematurely by Stress (SIPS). The work presented hereafter was made on a new model of senescence induced prematurely by stress from ultraviolet Brays (UVB). The human fibroblast model was put under repeated UVB stress, causing SIPS. Several ageing biomarkers were used in order to characterise the cells that underwent stress:. an increase in the proportion of positive cells with senescence associated $\beta$-galactosidase activity (SA $\beta$-gal) measured by a specific coloration,. the proportion in the different morphological stages that fibroblasts undergo during culture visualised by microscopic observation,. the expression of genes known for overexpressing during senescence, particularly fibronectin and apolipoprotein J, measured by Real Time-PCR,. the common deletion of 4,977 bp in mitochondrial DNA, evaluated by nested PCR. Studying the variation of these 4 biomarkers, we have evaluated the protective effect of a Laminaria digitata extract (LDE) that can be used as a natural active ingredient for anti-ageing cosmetics.

• 보존과학연구
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• s.30
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• pp.93-102
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• 2009

This study was carried out to investigate the effect of artificial accelerated ageing treatment on the permanence of lining papers produced from Korea and Japan. As time gone by, organic cultural properties are affected by chemical and physical deterioration because of various factors including the conditions of preservation environment and their material properties. In the public historical storage or owned as private collections, are vulnerable to sever amages caused by poor preservation environment as well as by other natural factors. In this study, the deterioration behaviors of lining paper in optical & mechanical properties were discussed. Overall, lining papers produced from Korea showed lower reduction in mechanical strength properties compared to the lining papers produced from Japan.

• 한국유가공학회:학술대회논문집
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• 2005.06a
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• pp.13-35
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• 2005

The trend towards ageing populations has been observed over many years in Europe and the US but has accelerated significantly in developed countries in Asia including Japan and South Korea. In the latter country the elderly population (65+) has increased 5-fold between 1960 and 2000 and this group will comprise 40% of the population by 2050. This creates a new socio-economic group with specific demands and considerable spending power. As ageing occurs a range of changes occur in the body that can be moderated by adjustments in nutrition. A significant body of evidence points to changes in the balance of glutathione synthesis and utilisation as people age. Glutathione is the most important natural anti-oxidant of the body and the amounts present can become limited by available cysteine in the diet. A cysteine-enriched peptide product, Cysteine Peption$^{TM}$ has been developed by DMV International for dietary supplement and food applications. A qualitative consumer trial has indicated benefits including improved sleep and more energy. Animal and clinical trials will be described that provide indications on bioavailability and possible mechanisms of action of Cysteine Peption$^{TM}$ with particular focus on the ageing population.

• 한국정책학회보
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• v.21 no.1
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• pp.337-361
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• 2012

This study is conducted to provide empirical evidences which support that the problems of social isolation and loneliness of elderly can be alleviated by intervening the inter-generational relationship of the elderly by means of active ageing policy. The major empirical challenge to address this question is the possibility of selection bias caused by reversed causal relationship. To address this challenge, I constructed comparison group with 'Eligible Non-Participants' (ENP), and used instrumental variable method to estimate the empirical model. My findings indicate that inter-generational relationship, both in the aspects of economical solidarity and associational solidarity, is significantly improved as time use pattern of the elderly becomes more active. The improvement effect is intensively observed for the group of elderly who do not live with their adult children. The important policy implication of these findings is that the improvement of inter-generational relationship can be added as a new benefit of active ageing policy.

• 한국노년학
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• v.32 no.2
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• pp.359-376
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• 2012

The present study empirically confirmed knowledge of ageing and quality of contact were predictors affecting middle-aged Korean's ageism against the elderly and verified mediating role of intergroup anxiety between not only knowledge of ageing but also quality of contact and ageism. To investigate causalities of factors, we purposively collected 400 samples from 20 Dongs evenly located in Jeonju and 393 samples, survived the data cleaning such as missing values, outliers, normality and covariance conditions, were analyzed by frequency, factor analysis, reliability, confirmatory factor analysis and structural model analysis. Followed were the selected contributions of the present study. First, the knowledge of ageing and quality of contact were predictors of ageism mediated by intergroup anxiety. Second, the knowledge of ageing and quality of contact did not directly affect middle-aged Korean's ageism against the elderly. Third, intergroup anxiety had strong effect on ageism. The contributions suggested increasing knowledge of ageing and providing contact experience to middle-aged Korean as combating strategy against ageism.

• Journal of Welding and Joining
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• v.13 no.2
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• pp.122-131
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• 1995

The effects of cooling rate on the microstructures, precipitation of Cu-cluster, .epsilon.-Cu and impact toughness of high strength low alloy(HSLA) steel were studied using hardness tester, impact tester, DSC(differential scanning calorimetry), AES(auger electron spectroscopy) and TEM(transmission electron microscopy). Not only the Cu-precipitates but also the segregation of Cu, As, Sb, P, S, N, Sn along grain boundary were not observed at the specimens heat treated from 800.deg. C to 300.deg. C with the cooling time of 12-125 sec. The Cu-cluster, .epsilon.-Cu are formed by introducing ageing after cooling and the effect of precipitates on hardening increase after cooling was the same in all cooling rate. The peak hardness was obtained at an ageing of 500.deg. C in all cooling conditions. The impact energy become higher as the cooling time increases. This fact can be explained to be due to the tempering effect applied on the cooling stage since the present alloy has a relatively high Ms temperature and the local high concentration of the retained austenite.

• The Journal of Korean Medicine
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• v.38 no.2
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• pp.31-40
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• 2017

Objectives: We investigated the effect of acupuncture on memory function in relation with neurogenesis in old rats. Methods: In this study, a step-down avoidance task for short-term memory and Y-maze task for spatial memory capability were conducted. Western blot analysis for brain-derived neurotorphic factor (BDNF) and tyrosine kinase B (TrkB), and immunohistochemistry for 5-bromo-2'-deoxyuridine (BrdU) were performed. Results: Short-term memory and spatial memories were decreased in the old-aged rats. Expressions of BDNF and TrkB in the hippocampus were significantly decreased in the old-aged rats. Neurogenesis in the hippocampal dentate gyrus was also decreased in the old-aged rats. However, acupuncture treatment alleviated impairment of short-term and spatial memories induced by ageing. Acupuncture also increased the expressions of BDNF and TrkB and enhanced neurogenesis in the hippocampus. The present study showed that acupuncture alleviated ageing-induced short-term and spatial memory loss by increasing of BDNF and neurogenesis. Acupuncture at ST41-acupoint showed most potent effect than at ST36-acupoint or non-acupoint. Conclusions: Acupuncture might be used as the effective therapeutic modality to ameliorate the age-related decrease of brain functions.

• Research in Community and Public Health Nursing
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• v.9 no.1
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• pp.64-71
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• 1998

This study uses [the instrument of ageing anxiety] in order to find if a negative prejudice against the old affects the attitude toward sex of the aged. The result shows no significant relation between ageing anxiety and the knowledge of and attitude toward sex of the aged. However, it does show that the higher the ageing anxiety is, the lower the knowledge of sex and the more restrictive the attitude toward it. The knowledge of and attitude toward sex of the aged shows meaninggul changes after education. Nursing students who were educated come to have more knowledge about and are more open to it. This result supports the preposition of this study. As society grows older the endeavour to guarantee a high-quality life for the old is necessary and the old should be regarded as an entity which has its own characteristic desires. Especially for the old to enjoy a good life as a sexual being, the mystical barriers about sex and old age ought to be removed. In the future the old themselves may maintain sexual desires regardless of age and society will be required to correct its prejudice against the old having sex. Particularly nursing students, as an effort to provide the old with overall care, should examine the elderly's sexual desires in a physical, psychological, and social context and consider the normal sexual changes occuring during the aging process and finally integrate this information into their nursing plans. In order to fulfill this role successfully they should overcome their own prejudice and educate themselves about this particular problem. As the proportion of the old becomes bigger and the concern about the quality of their life grows, sex among the old will become more important in the nursing field. By putting an educational mediation programme into operation with nursing students and estimating the effect, this study supplies the foundation to activate new educational programmes. In short it tells us that education can be a practical method to confront the myth and conventions concerning sex among the aged.

• Asian-Australasian Journal of Animal Sciences
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• v.16 no.8
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• pp.1218-1223
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• 2003

The effects of type (high and low voltages) and time (3, 40 and 60 min postmortem) of stimulation on drip loss and meat color at 24 h post-mortem were determined on M. longissimus dorsi of 38 crossbred steers and heifers. In addition, the effect of pH early postmortem (70 min postmortem) on the rate and extend of meat tenderization was examined. Either high or low voltage stimulation at 3 min showed a tendency for faster pH decline (p=0.052) and higher drip loss (p=0.08), and improved the color dimensions of L*, a* and b* (p<0.01), compared to stimulation at 40 min. This was equivalent to approximately one unit of an AUSMEAT color chip. On the other hand, although there were significant differences in pH decline between high voltage stimulation at 40 and 60 min, and between low voltage stimulation at 40 min and control sides, drip loss and meat color did not differ significantly (p>0.05). The results suggested that early application of stimulation, regardless of type of stimulation, improved overall meat color at 24 h postmortem through its effect on faster glycolysing rate. However, if the pH decline was moderate, the benefit of electrical stimulation on meat color was not apparent. An intermediate pH decline resulted in the lowest shear force. Due to differential ageing rates the optimum pH at 70 min postmortem increased with ageing time from 5.96, 6.07, 6.12 and 6.14 for 1, 3, 7 and 14 days postmortem, respectively. This implied that a small difference in the rate of pH decline was important, especially carcasses stimulated for very early postmortem, and the optimum rate of pH decline varied with intended ageing period. The study suggests that the beneficial or adverse effects of electrical stimulation on drip loss, meat color and tenderness is determined by the rate of pH decline, rather than by stimulation treatment and time of application per se.

• Survey Research
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• v.7 no.2
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• pp.71-95
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• 2006

This article presents strengths of Computer-Assisted Personal Interviewing(CAPI) in social surveys with complicated questionnaires, from examples of a pilot and the first year surveys of the Korean Longitudinal Study of Ageing(KLoSA). This study focuses on how to improve the quality of data by using CAPI and finds five strengths among others. First of all, CAPI can contribute to reducing response errors by structuring the logic and path of questionnaires, setting a response range, and maintaining response consistency. Second, CAPI enhances convenience of interviewing by allowing customized questions and automatic calculation and scoring. It also allows the 'help' function. Third, its random arrangement of questions prevents response order effect and/or questions order effect. Fourth, CAPI can raise the response rate by reducing item non-responses. Fifth, it makes it easy monitoring interviewing, thus helps supervising interviewers and modifying questionnaires when necessary. These merits of CAPI contribute to reducing possible errors in the process of interviewing, therefore improve the data quality.