• 산업경영시스템학회지
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• 제45권3호
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• pp.90-103
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• 2022

The purpose of this study is first to understand whether technology innovation capability, which is considered an important factor in the Root companies, directly affects the business performance of the company. Second, it was attempted to determine whether internal resources deemed necessary for a company's continuous competitive advantage and excellent business performance play a mediating role in the technological innovation capability of the Root companies and the business performance. The implications of this study derived from the research results are as follows: Among the elements of technology innovation capability, R&D capability, positively affects both financial and non-financial performance. It was confirmed that the investment ratio could positively affect financial performance such as sales, market share, and yield, and non-financial performance such as corporate image, employee satisfaction, and productivity. Among the factors of technology innovation capability, the technology innovation system positively affects both financial and non-financial performance. Therefore, it can be said that securing rights to owned technology, establishing technology and funding, efficient use of resources, etc., affects financial performance such as sales or market share of a company, and affect the company's production capacity, image, and employee satisfaction. It has been verified that internal resources, including financial, physical, and human resources, can mediate between the three elements of technology innovation capability and corporate financial and non-financial performance.

• Journal of Microbiology and Biotechnology
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• 제34권4호
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• pp.838-845
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• 2024

Excessive alcohol consumption can have serious negative consequences on health, including addiction, liver damage, and other long-term effects. The causes of hangovers include dehydration, alcohol and alcohol metabolite toxicity, and nutrient deficiency due to absorption disorders. Additionally, alcohol consumption can slow reaction times, making it more difficult to rapidly respond to situations that require quick thinking. Exposure to a large amount of ethanol can also negatively affect a person's righting reflex and balance. In this study, we evaluated the potential of lactic acid bacteria (LAB) to alleviate alcohol-induced effects and behavioral responses. Two LAB strains isolated from kimchi, Levilactobacillus brevis WiKim0168 and Leuconostoc mesenteroides WiKim0172, were selected for their ethanol tolerance and potential to alleviate hangover symptoms. Enzyme activity assays for alcohol dehydrogenase (ADH) and acetaldehyde dehydrogenase (ALDH) were then conducted to evaluate the role of these bacteria in alcohol metabolism. Through in vitro and in vivo studies, these strains were assessed for their ability to reduce blood alcohol concentrations and protect against alcohol-induced liver damage. The results indicated that these LAB strains possess significant ethanol tolerance and elevate ADH and ALDH activities. LAB administration remarkably reduced blood alcohol levels in rats after excessive alcohol consumption. Moreover, the LAB strains showed hepatoprotective effects and enhanced behavioral outcomes, highlighting their potential as probiotics for counteracting the adverse effects of alcohol consumption. These findings support the development of functional foods incorporating LAB strains that can mediate behavioral improvements following alcohol intake.

• Asian Pacific Journal of Cancer Prevention
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• 제16권5호
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• pp.2093-2098
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• 2015

In patients with multiple myeloma (MM), once-weekly intravenous injection or twice-weekly subcutaneous injection (SC) of bortezomib has been proven to offer non-inferior efficacy to standard twice-weekly intravenous administration, with an improved safety profile. However, whether once-weekly SC bortezomib can further reduce the incidence rate of peripheral neuropathy (PN) and not compromise the efficacy remains to be investigated. 25 patients of MM treated with once-weekly SC bortezomib were reviewed in this study. The median treatment cycles were 4 (range, 2-9 cycles). Complete response (CR) rate was 52%, ${\geq}$very good partial response (VGPR) rate was 72%, and ${\geq}$partial response (PR) rate was 84%. 1-year and 2-year PFS rate was 63.0% and 34.3%, respectively, and 2-year OS rate was 100%. Any grade of PN was reported in 9 patients (36.0%), with 7 patients (28.0%) had grade 1 PN, and 2 patients (8.0%) had grade 2 PN. No patients reported grade 3/4 PN in this cohort. In conclusion, once-weekly subcutaneous administration of bortezomib offers excellent efficacy with a further improved safety profile, especially with regard to PN. It needs to be validated in future prospective randomized trials.

• 한국산학기술학회논문지
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• 제11권11호
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• pp.4273-4281
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• 2010

본 연구는 셀프리더십의 하위요소인 리허설, 자기설정목표, 자기존중이 임파워먼트 및 자기효능감에 미치는 영향을 알아보고, 임파워먼트와 자기효능감이 혁신성에 어떠한 영향을 미치는 지 조사하였다. 본 연구의 목적을 위하여 국내 외국계 기업 4개를 대상으로 설문조사를 실시하였으며, 수집한 설문지 중 305부의 응답내용을 분석대상으로 하였으며, SPSS 18.0과 AMOS 8.0을 사용하여 구조방정식 모형을 검증하였다. 연구결과는 다음과 같다. 셀프리더십의 하위요소인 리허설과 자기존중은 임파워먼트를 높이지만, 자기설정목표가 임파워먼트에 미치는 영향력은 검증되지 않았다. 또한 셀프리더십의 세 가지 하위요소는 모두 자기효능감에 정(+)의 영향력을 미치며, 임파워먼트는 혁신성을 높이는 것으로 나타났다. 하지만 자기효능감이 혁신성에 미치는 영향력은 검증되지 않음을 알 수 있었다. 연구결과를 바탕으로 시사점과 연구의 한계점 및 향후 연구방향이 논의되었다.

• The Journal of Asian Finance, Economics and Business
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• 제9권4호
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• pp.399-408
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• 2022

Corporate governance and innovation have been a hot topic in recent boardroom talks, whether in the trade or manufacturing industries. Governance innovations are highly significant for the survival of the motor vehicle industry like Honda, Nissan, New General Motors, and Toyota. The study chooses the motor vehicle industry which crosses the age of a century and sufficient corroborative support exists with the perspective of distinctive objectives. Using the population of all the automobile companies listed on the Pakistan stock exchange (PSX), we distill automobile companies to evaluate the firm performance using the panel data regression approach. The results show that there is a significant relationship between gender diversity, audit committees, and firm performance. Further, board size also has a positive impact on firm performance. We identify that the governance mechanism of firms found in default of the frequency of audit committee meetings. By considering results, only limited knowledge of finance directors and also very few numbers of female directors are on the board. Empirical findings of this work might be useful for policymakers in attempting to draft a corporate governance framework better able to monitor the financial performance of firms through female directors and also serve as a catalyst for the regulators of electric vehicles.

• Journal of Information Technology Applications and Management
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• 제18권4호
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• pp.169-181
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• 2011

The study developed the ideas of innovation resistance attitude in view of innovation delay, rejection, and objection. Authors developed the idea of innovation resistance attitudes of customers in view of innovation diffusion process. The study categorized the idea of resistance such as delay, rejection, and objection. The study hired the structural equation modeling to evaluate the relationships among the consumers' subjective variables such as incongruence, uncertainty, perceived performance, peer usage, and tradition orientation those were factored out by the survey test. These measured variables were analyzed into the innovation resistance related latent variables. The study provides the basic treatment to introduce new technologies and products to the superficially resisting customers. Those resisting customers might be future late adopters. The research results provide the basic arguments for prerequisite treatment to introduce smart phone in the global market place.

• Journal of Information Technology Applications and Management
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• 제23권4호
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• pp.71-82
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• 2016

The purpose of this study is to prove empirically that technology investment propency factors (TIPFs) refect on the technological competitive advantage (TCA) and management performance. It includes the role of open technology innovation (OTI) approach is mediate to TCA from technology investment propensity. Especially the three TIPFs are market orientation, innovation orientation and strategy orientation. The analysis were performed based on the respondents' data from 181 firms focusing to technology innovation and information technology. The suggested research assumptions including structured equation model were proved. Therefore, this study emphasizes that CEO or CTO must concentrate on innovative, strategic and market oriented propensity when he makes a decision on technology investment. An open innovation approach is effective for getting high TCA and management performance in technology intensive firms such as technology innovation and information technology.

• 대한안전경영과학회지
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• 제14권2호
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• pp.229-236
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• 2012

This paper reviewed the relationship between organizational justice and innovative behavior, and the moderating effect of gender. The results of multiple regression analysis, based on the responses from 412 employees in small business, showed that distributive justice, procedural justice and interactional justice have positive relationships with innovative behavior(process innovation, operation innovation, service innovation). In moderating effects, distributive justice more positively related with innovative behavior(process innovation and operation innovation) in male-group than in female-group. But interactional justice more positively related with innovative behavior(operation innovation and service innovation) in female-group than in male-group.

• 대한안전경영과학회지
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• 제13권3호
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• pp.191-197
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• 2011

This paper reviewed the relationship between organizational commitment and incremental innovation, and the moderating effect of tenure. The results of hierarchical multiple regression analysis, based on the responses from 434 employees in service industry, showed that affective and nonnative commitment relates positively with incremental innovation, but continuous commitment relates negatively with incremental innovation. In the moderating effects, affective commitment appeared to have more negative effect on operation innovation in longer tenure employee group, and also nonnative commitment appeared to have more negative effect on process and service innovation in longer tenure employee group.

• 품질경영학회지
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• 제52권1호
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• pp.173-183
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• 2024

Purpose: This study highlights the importance of emphasizing entrepreneurship and sustainability among managers to address the challenges of Industry 6.0, especially in situations of increasing environmental uncertainty. The research model reveals the important structural relationship between entrepreneurship, sustainability, and innovation performance, and through empirical analysis, we sought to confirm that entrepreneurship in the 6th industry is related to technological innovation. Methods: A survey was conducted targeting 6th industry entrepreneurs, and the relationship was analyzed using SPSS and AMOS. Results: Despite a non-significant direct relationship between entrepreneurship and innovation performance, a notable effect of sustainability on innovation performance was identified. This highlights the fact that entrepreneurship contributes to firm performance through innovation activities, especially in the form of technological innovation. Conclusion: This study highlights the essential characteristics of entrepreneurship and sustainability, highlights their interconnectedness and suggests that their inclusion in the same management activities improves performance.