• Title/Summary/Keyword: adhesion prevention

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A Study on the Eco-Friendly Durable Pre-Painting for Concrete Structure (콘크리트 구조물의 친환경 내구성 도장에 관한 기초 연구)

  • Jo, Byung Wan;Choi, Ji Sun;Lee, Seong Won
    • Journal of the Korea institute for structural maintenance and inspection
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    • v.17 no.2
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    • pp.110-116
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    • 2013
  • A concrete structure has become bigger and higher because of development of construction technology and a change in construction environment. Also it tends to focus on repairing, reinforcement and exterior in harmony with environment for structure maintenance and performance improvement. The research is about eco friendly durable painting applicable to concrete structure using civil and architecture. it purpose to improve external beauties and durable problems due to flexibility by variation of temperature, adhesion of exterior wall, crack and delamination in existing organic and mineral painting. For those problems, we made a eco friendly pre-paint that is made with preliminary treatment mixture as a highly enriched waterproof agent and adhesive increasing agent in preprocessing mixture. Then we performed an experiment on durability of prevention neutralization of concrete, durability abrasion, hiding power, adhesion, temperature resistance and resistance to chemical attack. The result of an experiment shows that hiding power is over 0.96 in standard test, durability abrasion test got higher value 1mg than water paint 75mg and tensile strength is 6 times higher than standard waterproof specification.

Fabrication and Characterization of Porous PLLA Scaffolds with Gentamicin Sulfate Release System (겐타마이신 설페이트를 서방화한 다공성 PLLA 지지체의 제조와 물성평가)

  • 최명규;강길선;이일우;이종문;이해방
    • Polymer(Korea)
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    • v.25 no.3
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    • pp.318-326
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    • 2001
  • PLLA scaffold loaded with gentamicin sulfate (GS) was prepared by emulsion freeze-drying method for the prevention of infection and the improvement of wettability. i.e., the cell- and tissue-compatibility. GS-loaded PLLA scaffolds were characterized by scanning electron microscopy (SEM), mercury porosimetry and blue dye intrusion, and the GS release pattern was analyzed by high performance liquid chromatography (HPLC). GS-loaded PLLA scaffolds with porosity above 50%, medium pore size ranging from 30 to 57 ${\mu}{\textrm}{m}$ (with larger pore diameters greater than 150 ${\mu}{\textrm}{m}$), and specific pore area in the range of 35 to 75($m^2$ /g )were manufactured by varying processing parameter as GS concentration. It was observed that GS-loaded PLLA scaffolds were highly porous with good interconnections between pores for allowing cell adhesion and growth. These scaffolds may be applicable for scaffold as structures that facilitate either tissue regeneration or repair during reconstructive operations.

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Platysma Flap with Z-Plasty for Correction of Post-Thyroidectomy Swallowing Deformity

  • Jeon, Min Kyeong;Kang, Seok Joo;Sun, Hook
    • Archives of Plastic Surgery
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    • v.40 no.4
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    • pp.425-432
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    • 2013
  • Background Recently, the number of thyroid surgery cases has been increasing; consequently, the number of patients who visit plastic surgery departments with a chief complaint of swallowing deformity has also increased. We performed a scar correction technique on post-thyroidectomy swallowing deformity via platysma flap with Z-plasty and obtained satisfactory aesthetic and functional outcomes. Methods The authors performed operations upon 18 patients who presented a definitive retraction on the swallowing mechanism as an objective sign of swallowing deformity, or throat or neck discomfort on swallowing mechanism such as sensation of throat traction as a subjective sign after thyoridectomy from January 2009 till June 2012. The scar tissue that adhered to the subcutaneous tissue layer was completely excised. A platysma flap as mobile interference was applied to remove the continuity of the scar adhesion, and additionally, Z-plasty for prevention of midline platysma banding was performed. Results The follow-up results of the 18 patients indicated that the definitive retraction on the swallowing mechanism was completely removed. Throat or neck discomfort on the swallowing mechanism such as sensation of throat traction also was alleviated in all 18 patients. When preoperative and postoperative Vancouver scar scales were compared to each other, the scale had decreased significantly after surgery (P<0.05). Conclusions Our simple surgical method involved the formation of a platysma flap with Z-plasty as mobile interference for the correction of post-thyroidectomy swallowing deformity. This method resulted in aesthetically and functionally satisfying outcomes.

Effects of Exercise Program Intervention on Muscle Activity in Rotator Cuff Repair Patient (운동프로그램 중재가 돌림근띠 복원술 환자의 근 활성도에 미치는 영향)

  • Kang, Jeong-Il;Moon, Young-Jun;Park, Seung-Kyu;Lee, Joon-Hee;Yang, Dae-Jung;Choi, Hyun;Jeong, Dae-Keun;Kim, Yong-Nam;Kwon, Hye-Min
    • The Journal of Korean Physical Therapy
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    • v.25 no.2
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    • pp.56-63
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    • 2013
  • Purpose: This study was conducted in order to examine how an effective rehabilitation exercise program influences the activity of shoulder muscles, and to help the clinical application of a rehabilitation program, for prevention and relief of pain, adhesion, and joint stiffness of patients who undergo rotator cuff repair. Methods: Nine test subjects were placed randomly into each group for a total of 27 subjects and exercise program interventions according to the group were conducted for six weeks, after which maximum voluntary isometric contraction (%MVIC) value was re-measured for supraspinatus muscle, infraspinatus muscle, serratus anterior muscle, and middle deltoid muscle in all groups in order to compare changes in muscle activity before and after the experiment in order to perform comparative analysis of changes in muscle activity between groups, based on which four experimental hypotheses were confirmed. Results: Changes in muscle activity according to %MVIC showed a statistically significant difference (p<0.01) (p<0.001) in all muscles, except the middle deltoid muscle, and post-verification results showed that changes in muscle activity according to %MVIC were greater in test groups I and II, compared with the control group, for the supraspinatus muscle, infraspinatus muscle, and serratus anterior muscle. Conclusion: Therefore, rehabilitation through use of the methods described above should be applied efficiently in clinical settings and more research in development of much more efficient rehabilitation program interventions must be conducted.

Considerations for the Management of Cryptotia Based on the Experience of 34 Patients

  • Kim, Seok-Kwun;Yoon, Chung-Min;Kim, Myung-Hoon;Kim, Min-Su;Lee, Keun-Cheol
    • Archives of Plastic Surgery
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    • v.39 no.6
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    • pp.601-605
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    • 2012
  • Background Cryptotia is a congenital ear deformity in which the upper pole appears buried beneath the mastoid skin. Cryptotia is a common auricular malformation among Asians. The aim of this paper is to examine the surgical techniques for and complications of 34 cryptotic patients. Methods Surgery was performed for 34 cryptotic deformities (January 2005 to January 2012). Twenty-two patients (64.7%) were classified as having type I cryptotia, and 12 patients (37.5%) type II cryptotia. Among the type I cryptotia patients, 8 patients had mild deformity and 14 severe deformity. Among the type II cryptotia patients, 10 patients had mild deformity and 2 severe deformity. Results The mild deformities were corrected via Z-plasty, V-Y plasty, full-thickness skin graft, and transposition flap, while the severe deformities were corrected via cartilage graft or Medporfor the spread of cartilage adhesion of antihelix. There were two cases of reinvagination in the autologous cartilage graft group. Implant exposure occurred with Medpor (two cases). There were two cases of hypertrophic scar on the previous surgical wound with Medpor. There were no complications in the 18 patients who had mild deformities. Conclusions The type I cryptotia patients had more severe deformities than the type II cryptotia patients. As most of the type II cryptotia patients had only mild deformities, their deformities were corrected without using autologous conchal cartilage graft or Medpor, except for two patients. Through more case analyses, researchers should make an effort to identify methods for recurrence and prevention of complication.

Prevention of thin film failures for 5.0-inch TFT arrays on plastic substrates

  • Seo, Jong-Hyun;Jeon, Hyung-Il;Nikulin, Ivan;Lee, Woo-Jae;Rho, Soo-Guy;Hong, Wang-Su;Kim, Sang-Il;Hong, Munpyo;Chung, Kyuha
    • 한국정보디스플레이학회:학술대회논문집
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    • 2005.07a
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    • pp.700-702
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    • 2005
  • A 5.0-inch transmissive type plastic TFT arrays were successfully fabricated on a plastic substrate at the resolution of $400{\times}3{\times}300$ lines (100ppi). All of the TFT processes were carried out below $150^{\circ}C$ on PES plastic films. After thin film deposition using PECVD, thin film failures such as film delamination and cracking often occurred. For successful growth of thin films (about 1um) without their failures, it is necessary to solve the critical problem related to the internal compressive stress (some GPa) leading to delamination at a threshold thickness value of the films. The Griffith's theory explains the failure process by looking at the excess of elastic energy inside the film, which overcomes the cohesive energy between film and substrate. To increase the above mentioned threshold thickness value there are two possibilities: (i) the improvement of the interface adhesion (for example, through surface micro-roughening and/or surface activation), and (ii) the reduction of the internal stress. In this work, reducing a-Si layer film thickness and optimizing a barrier SiNx layer have produced stable CVD films at 150oC, over PES substrates

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The Effect of Sodium Carboxymethylcellulose on Prevention of Post-operative Pleural and Pericardial Adhesions in Dogs (개에서 Sodium Carboxymethylcellulose의 흉막 및 심낭에 대한 유착방치효과)

  • 정동규;정종태;이경갑;김희석;최민주
    • Journal of Veterinary Clinics
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    • v.17 no.2
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    • pp.368-375
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    • 2000
  • 개의 개흉술이나 개심술 후에 주요 합병증인 유착에 대한 sodium carboxymethyl- cellulose (SCMC)의 효과를 평가하기 위하여 1% SCMC총액을 흉막 및 심낭에 적용하였다. 10두의 개를 SCMC투여 군과 생리식염수 투여 군으로 각각 5두씩 배치하고, 개흉 후 4번째 메서 7번째 늑골의 늑연골 연접부 부위에 찰과상을 유도하였고 심낭 절개 후 심낭의 내측 및 닿는 심근에 각각 $2{\times}2cm$크기로 찰과상을 유발하였다. 찰과상 유발 후 생리식염수 투여 군은 멸균 생리식염수를 3.5m1/kg을, SCMC투여 군은 같은 용량의 1% SCMC를 흉강 및 심낭 내에 각각 도포 하였다. 수술 전후에 CBC와 혈장 plasminogen치를 측정하였다. 유착 정도 는 수술 30일 후에 0-4로 점수화하여 판정하였다 십장과 심낭의 평균 유착치는 SCMC투여 군이 2.4$\pm$0.8, 생리식염수 투여군이 $3.7{\pm}0.9$로 나타나 SCMC 투여군에서 유착 발생이 유의 성 있게 낮았다(p<0.01). 폐염과 흉막간의 평균 유착치는 SCMC 투여군이 1.7$\pm$0.2이었고, saline 투여군은 $3.5{\pm}0.8$로. SCHC투여 군에서 유착 발생이 유의성 있게 낮았다(p<0.01). Saline 투여군의 혈중 plasminogen 농도는 술 후 1일에 $28.2{\pm}5.677$로 감소하였고,술 후 7일에 $47{\pm}1.4%$.증가하였다(p<0.05). SCMC 투여군에서는 실험적 수술 1일 후 $27.1{\pm}10.3$로 감소하였고 7일 후에는 $30.3{\pm}21.6%$로 증가(p<0.01)하였으나 두 군간의 유의적인 차이는 없었다 이 상의 결과로 볼 때 개흉술 및 개심술시 1% SCMC를 투여하여 흉강 내의 유착을 방지함으로써 재수술이 필요한 경우에 수술의 어려움과 조직손상의 위험을 감소시킬 것으로 사료된다.로 사료된다.

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Study on Antitumor Activity and Antimetastatic Effects of Bruceae Fructus(BF) (압단자(鴨蛋子)의 항암활성(抗癌活性) 및 항전이(抗轉移) 효과(效果)에 관(關)한 연구(硏究))

  • Lee, Dong-hoon;Kim, Sung-hoon;Kim, Dong-hee
    • Journal of Haehwa Medicine
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    • v.10 no.2
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    • pp.11-19
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    • 2002
  • To evaluate the antitumor activity and antimetastatic effects of Bruceae FructusCBF), studies were done experimentally. The results were obtained as follows : 1. In cytotoxicity against A549, SK-MEL-2, MCF-7 and XF498 cell concentration inhibiting cell growth up to below 50% of control was recognized at $25{\mu}g/m{\ell}$ of BF. Also BF inhibited cell growth up to below 50% of control against HCT15 cell at $12.5{\mu}g/m{\ell}$, so it showed stronger cytotoxicity against HCT15 cell than another cancer cell. 2. In Inhibitory effect on activity of DNA topoisomerase- I, the $IC_{50}$ was shown $10-50{\mu}g/m{\ell}$ of BF. 3. The T/C% was 143.4 in BF treated group in S-180 bearing ICR mice. 4. The concentration inhibiting adhesion of A549 and SK-OV-3 to complex extracellular matrix up to below 30% of control was recognized at $1{\mu}g/m{\ell}$ of BF. 5. In pumonary colonization assay, a number of colonies in the lungs were decreased significantly in BF treated group as compared with control group. These results suggested that BF extracts might be usefully applied for prevention and treatment of cancer.

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Study on Antitumor Activity of Hwalheuldaibotang(HDBT) (활혈대보탕(活血大補湯)의 항암활성(抗癌活性) 및 항전이(抗轉移) 효과(效果)에 관(關)한 연구(硏究))

  • Bae, Moon-yong;Kim, Dong-hee
    • Journal of Haehwa Medicine
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    • v.9 no.2
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    • pp.97-109
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    • 2001
  • To evaluate the antitumor activity and antimetastatic effects of HDBT, studies were done experimentally. The results were obtained as follows: 1. HDBT extracts didn't show cytotoxicity against BALB/C mouse lung fibroblast cell. 2. In cytotoxicity against A549, SK-OV-3, B16-BL6 and HT1080 concen- tration inhibiting cell growth up to below 30% of control was recognized at $10^{-3}g/ml$ of HDBT. 3. The concentration inhibiting adhesion of A549 and B16-BL6 to complex extracellular matrix up to below 30% of control was recognized at $10^{-3}g/ml$ of HDBT. 4. In Inhibitory effect on activity of DNA topoisomerase I, the $IC_{50}$ was shown $200-300{\mu}g/m{\ell}$ of HDBT. 5. The T/C% was 137.9% in HDBT-treated group in S-180 bearing ICR mice. 6. In CAM assay, HDBT extracts inhibited angiogenesis significantly at $15{\mu}g/egg$ concentration as compared with control. 7. In pumonary colonization assay, a number of colonies in the lungs were decreased but insignificantly in HDBT-treated group as compared with control group. 8. In hematological changes in B16-BL6 injected C57BL/6, numbers of WBC were decreased significantly in HDBT-treated group but numbers PLT were increased insignificantly as compared with control. From above results it was concluded that HDBT could be usefully applied for the prevention and treatment of cancer.

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Study on Antitumor Activity and Radioprotective effects of Kamisasammaekmundongtang (가미사삼맥문동탕(加味沙蔘麥門冬湯)이 항암활성(抗癌活性)과 방사선부작용(放射線副作用) 억제효과(抑制效果)에 미치는 영향(影響))

  • Park, Yang-chun;Kim, Byeong-tak
    • Journal of Haehwa Medicine
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    • v.8 no.1
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    • pp.403-424
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    • 1999
  • To evaluate the antitumor activity, antimetastatic and radioprotective effects of Kamisasammaekmundongtang(KSMT), studies were done experimentally. The results were obtained as follows: 1. In cytotoxicity against P388, A549 and B16-F10, KSMT was not showed satisfiable cytotoxicity as compared with control. 2. In Inhibitory effect on activity of DNA topoisomerase I, KSMT has strong inhibitory effect. 3. The inhibitory effect on adhesion of A549 to complex extracellular matrix was significantly increased at 0.5mg/ml, 1mg/ml of KSMT. 4. The T/C% was 122 in KSMT treated group in S-180 bearing ICR mice. 5. In antiangiogenetic effect on CAM assay, inhibitory rate was 33% in KSMT treated group. 6. In pulmonary colonization assay, a number of colonies in the lungs were decreased significantly in KSMT treated group as compared with control group. 7. By FACS analysis of splenic leukocyte after exposure to radiation by linear accelerator, T-helper cell, B cell and macrophage in KSMT treated group were significantly increased while splenocytes were decreased in control group. 8. In histological changes of jejunum of $Bald{\setminus}C$ mice after exposure to radiation by linear accelerator, exclusion and fusion of villi were decreased as compared with control group. But in duodenum and ileum, exclusion and fusion of villi were not decreased as compared with control group. 9. WBC, PLT were increased in KSMT treated group as compared with control group after exposure to radiation by linear accelerator, but the increasing effect was not significant. Above results suggest that KSMT may be useful in prevention of cancer metastasis and protection from damage by radiotherapy. But the further study of KSMT would be demanded.

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