• 동의생리병리학회지
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• 제17권5호
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• pp.1194-1201
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• 2003

Jaeumgenby-tang(JGT) have been used in oriental medicine for many centries as a therapeutic agent of vertigo caused by deficiency of qi(氣) and blood(血). Effect of Aurantii Fructus(AF) take off the phlegm by promoting the circulation of qi, Gastrodae Rhizoma(GR) has effects treating for headarch, vertigo by calming the liver and suppressing hyperactivity of the liver-yang (陽). I investigated whether injection of JGT adding AFㆍGR extract(JTG) affects cerebral hemodynamics [regional cerebral blood f1ow(rCBF), pial arterial diameter(PAD) in cerebral ischemia rats by MCA occlusion method, and I designed to make manifest whether JTG is mediated by adrenergic β-receptor, cyclooxygenase or guanylate cyclase. The changes of rCBF was determinated by laser-doppler flowmetry(LDF), and the changes of PAD was determinated by video microscope and width analyzer. The results were as follows in cerebral ischemic rats; The changes of rCBF and PAD were increased stabilizly by treatment with JTG(10 ㎎/kg, i.v.) during the period of cerebral reperfusion, and pretreatment with propranolol and indomethacin were increased JTG induced increase of rCBF and PAD during the period of cerebral reperfusion. Pretreatment methylene blue was decreased JTG induced increase of rCBF and PAD during the period of cerebral reperfusion. In conclusion, JTG causes a diverse response of rCBF and PAD, and action of JTG is mediated by adrenergic β-receptor and cyclooxygenase. I suggest that JTG has an anti-ischemic effect through the improvement of crebral hemodynamics.

• 분석과학
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• 제11권3호
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• pp.222-228
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• 1998

15종의 분자량이 낮은 휘발성 유기용매 물질류를 사용하여 에탄올에 대한 분리분석 등을 검토하기 위하여 5가지 충진 칼럼과 2가지 모세관 칼럼을 이용한 기체 크로마토그래피 실험에서 Gaskuropack 54 와 DB-1 column이 좋은 분리능을 보여 주었다. GC 기화평형법에 의한 생체물 시료의 알코올 농도 측정에서 0.6N 과염소산, 1M 메타인산 및 염화나트륨 포화용액을 이용한 salt-effect 첨가실험은 그 중 염화나트륨 포화 용액이 알코올 농도값을 얻는데는 가장 안정된 값을 보였다. 혈액 및 각 조직의 시료들에서 시간에 따른 농도변화 실험에서 에틸알코올 농도 변화, 무게 변화, 함수분 변화, 헤마토크리트 변화치 영향을 함께 실험한 결과, 용기의 직경에 따르는 알코올 농도의 감소 변화를 1차 함수로 제안 할 수 있었으며, NISI에 조사 의뢰된 25 부검 사례에서 각 장기별 에틸알코올 분배농도에 대한 실험에서 뇌, 혈액, 신장, 비장, 간장, 폐장의 순으로 분포율이 낮아지는 결과를 얻을 수 있었다.

• The Korean Journal of Physiology
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• 제14권2호
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• pp.1-5
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• 1980

This study was undertaken to investigate the influence of prostaglandin $E_1(PGE_1)$ upon the activity of carbonic anhydrase and upon the inhibitory action of acetazolamide on carbonic anhydrase. The heparinized blood was sampled by cardiac puncture from Sprague-Dawley strain rats under ether anesthesia and was hemolysed by adding distilled water 1,000 times the amount of the blood. The activity of carbonic anhydrase of 0.1 ml of the hemolysate was measured by Maren's simplified micro-method. In the first experiment, the 7 rats were used, and the activity was measured by adding 0.1 ml of various concentrations of $PGE_1$(0.5, 1.25, 2.5, 5.0, 10 and $20\;{\mu}g/ml$). In the second experiment, the 6 rats were used and the activity was measured by adding 0.1 ml of $PGE_1(5\;{\mu}g/ml)$ and 0.1 ml of acetazolamide$(6{\times}10^{-7}M/l)$ respectively or simultaneously. Obtained results were as follows: 1) The activity of carbonic anhydrase was significantly inhibited by $PGE_1$ at doses of $0.5{\sim}10\;{\mu}g/ml$, maximally at a dose of $2.5\;{\mu}g/ml$, but inhibition was no more observed at a dose of $20\;{\mu}g/ml$. 2) The activity of the acetazolamide group was significantly less than that of the control group. 3) The activity of the $PGE_1+acetazolamide$ group was significantly less than those of the $PGE_1$ group and the acetazolamide group. It is inferred from the above results that the $PGE_1$ inhibits the activity of carbonic anhydrase dose-dependently and strengthens the inhibitory effect of acetazolamide on carbonic anhydrase.

• 한국섬유공학회:학술대회논문집
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• 한국섬유공학회 2007년도 학술발표회 논문집
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• pp.479-480
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• 2007

• Nuclear Engineering and Technology
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• 제2권4호
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• pp.279-287
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• 1970

An an element vanadium is most effective and next is noibium to strengthening the low carbon steels by small addition both on fine precipitation and five grain. The combination effect of vanadium plus niobium or vanadium plus molybdenum is much more effective than adding on element.

• Archives of Plastic Surgery
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• 제44권5호
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• pp.469-470
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• 2017

• 한국재료학회:학술대회논문집
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• 한국재료학회 2001년도 추계 학술발표강연 및 논문개요집
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• pp.126-126
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• 2001

• 한국구조물진단유지관리공학회 논문집
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• 제19권2호
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• pp.99-107
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• 2015

이 연구는 탄소나노튜브의 우수한 역학적 특성을 시멘트재료에 활용하여 역학적인 특성을 향상시키고자 현재 탄소나노튜브를 활용하고 있는 분야에서 탄소나노튜브의 분산성을 향상시키는데 사용되고 있는 계면활성제인 CTAB, SDBS, TX10 및 문헌조사를 통하여 유효하다 알려진 고성능감수제와 탄소나노튜브를 혼합한 모르타르 강도 시험체를 제작하여, 계면활성제 종류에 따른 특성 및 사용량에 따른 복합체의 강도변화를 평가하였다. 계면활성제 중에서는 고성능감수제가 작은 강도저하 현상 및 CNT 보강에 따른 높은 강도향상 효과를 나타내었다. 고성능감수제의 사용량에 따른 강도변화에서는 사용량 증가에 따라 실험체의 강도는 감소하였으며, CNT 보강에 따른 강도향상 효과는 시멘트 중량 대비 0.4% 이하에서는 나타나지 않으며 0.8%이상의 사용량에서 나타났다. 마지막으로 CNT의 사용량을 감소시키고 초음파로 처리한 탄소나노튜브를 보강한 시험체의 경우 탄소나노튜브를 혼합하지 않은 실험체보다 강도가 증가하는 결과를 얻을 수 있었다.

• 한국약용작물학회지
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• 제12권2호
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• pp.141-148
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• 2004

Two compounds from Gomisin N and Gomisin A were isolated from the fruits of Schizandra chinensis Baillon. The highest extraction yield as 21.36% was observed in the ethanol extract, compared to the yield obtained form the water extract. The extraction yields of the single compounds were measured to be 0.13 and 0.014 Gomisin A and Gomisin N, respectively. Approximately, 90% of the growth of human stomach adenocarcinoma cancer cells was inhibited after adding 1.0 g/l of the ethanol extract. The growth of the human normal lung cell was limited to 24% after adding the ethanol extract. The water extract lowered the specific secretion of $TNF-\acute{a}$ and IL-6 from T cells, $10.3{\times}10^{-4}\;pg/cell\;and\;12.1{\times}10^{-4}\;pg/cell$, respectively, compared to the ethanol extracts. On the other hand, a treatment with the ethanol extract increased the specific secretion of $TNF-\acute{a}$ and IL-6 from human T cells, to $11{\times}10^{-4}\;pg/cell\;and\;14.3{\times}10^{-4}\;pg/cell$, respectively. The crude ethanol extract had the highest effect on the differentiation of human promyelocytic leukemia cells compared to the other extracts and Gomisin A and N. In general, the biological activities of the extracts gradually decreased as the purification process proceeded, which suggests that higher immunostimulatory activities can be maintained by adding the crude extracts of the fruits rather than by adding a single compound.

• 한국산학기술학회논문지
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• 제10권2호
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• pp.412-417
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• 2009

실크 생사의 세리신 정착을 보다 효과적으로 하기위해 멜라민과 포르말린의 혼합액에 각종 첨가제를 첨가했을 때 첨가제가 세리신 정착에 미치는 영향을 살펴보았다. 멜라민과 포르말린의 혼합액으로 세리신을 정착할 때 수분침투 기능이 있는 계면활성제로 전처리라고 수세하지 않은 경우 견고한 정착이 이루어졌고, 정착액에 과산화수소를 첨가한 경우 정착 효과가 크게 떨어지면서 단사 간에 접착하는 문제가 발생했고, 하이드로를 첨가하여 $60^{\circ}C$에서 정착하는 경우에는 표백과 동시에 세리신 정착이 가능함을 확인했다. 낮은 농도의 수산화나트륨을 첨가한 알칼리 조건에서 멜라민을 추가함으로써 매우 견고한 세리신 정착 결과를 얻었으나 염산과 메탄을 추가는 정착에 그다지 효과적이지 못했고, 염화마그네슘 추가는 오히려 세리신 정착 견고성을 크게 저하시켰다.