• Journal of the Korean Academy of Child and Adolescent Psychiatry
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• 제28권1호
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• pp.4-13
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• 2017

The seeds of addiction are typically sown years prior to the onset of addictive substance use or engagement in addictive behaviors, due to the priming of the reward pathway (RewP) by alterations in the mechanism of stress-signaling from the hypothalamic-pituitary-adrenal axis (HPA) and related pathways. Excessive stress from a single-event and/or cumulative life experiences during childhood, such as those documented in the Adverse Childhood Experiences Study, is translated into neurobiological toxicity that alters the set-point of the HPA axis and limbic system homeostasis [suggested new term: regulation pathway (RegP)]. The resultant alteration of the RegP not only increases the risk for psychiatric and physical illness, but also that for early onset and chronic addictions by dysregulating the RewP. This paper reviews the interface of these symbiotic pathways that result in the phenotypic pathology of emotional dysregulation, cognitive impairment, and compulsive behaviors, as well as morbidity and shorter life expectancy when dysregulated by chronic stress.

• 가정과삶의질연구
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• 제25권5호
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• pp.31-46
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• 2007

The purpose of this study was to determine the differences in internet use motivations and problem behaviors among vocational high school students according to internet addiction and family system type. Five hundred vocational high school students from Daegu took part in the survey. The questionnaire survey consisted of an internet addiction self-assessment scale, a family system type scale, an internet use motivation scale, and a problem behavior scale. The data was analysed using MANOVA and Cronbach a, and the $Scheff\acute{e}$ test was used for post-hoc analysis. The major findings of this study were as follows: First, the study found significant differences in adolescent internet use motivation according to internet addiction. Adolescents in the high dangerous user group showed higher communicative, experiential, and addictive motivations than adolescents in potentially dangerous and normal user groups. Also, there were no significant differences in informative motivation according to internet addiction. Regardless of internet addiction, adolescents tend to use the internet to search for information and to solve problems. Second, there were significant differences in adolescents' problem behaviors according to internet addiction. More specifically, adolescents who were in the high dangerous user group displayed more problem behaviors toward their body, family, school, and society than adolescents in the potentially dangerous and the normal user groups. Third, an adolescent's family system type significantly influenced his/her internet use motivation. Adolescents from an extreme family showed higher communicative and addictive motivations than adolescents from middle and balanced families. Fourth, there were significant differences in the problem behaviors of adolescents according to family system types. Adolescents from an extreme family showed more problem behaviors toward their body, family, school, and society than adolescents from middle and balanced families.

• Journal of Ginseng Research
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• 제46권1호
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• pp.147-155
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• 2022

Background: Methamphetamine (METH) is the most widely used psychostimulant and has been known to exhibit reinforcing effects even after long abstinence. We showed the inhibitory effect of Korean Red Ginseng extract (RGE) on METH-induced addictive behaviors in animal models mimicking the human drug-use pattern. Methods: We first investigated the effect of RGE on the acquisition of METH-induced dependence using self-administration and conditioned place preference (CPP) tests. Additionally, further experiments such as METH-induced motivational behavior and seeking behavior were conducted. To study the underlying mechanism, dopamine receptor, dopamine transporter, and N-methyl-D-aspartate receptor were assessed through Western blot analysis. Results: Treatment with RGE significantly reduced METH-induced self-administration on a fixed-ratio 1 schedule of reinforcement. It could be also decreased a progressive ratio schedule, and inhibited METH-primed reinstatement. In CPP, RGE significantly prevented the development of METH-induced CPP. Moreover, RGE not only shortened the withdrawal period clearly, but also prevented the reinstatement of CPP. RGE treatment also reversed METH-induced overexpression of dopamine transporter, dopamine receptor D1, and NMDA receptor in the nucleus accumbens. Conclusion: Our findings reflect that RGE has therapeutic potential to suppress METH-induced addictive behaviors by regulating dopaminergic and NMDAergic system.

• 디지털융복합연구
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• 제12권4호
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• pp.409-418
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• 2014

본 연구는 일부 고등학생의 스마트폰 이용실태를 파악하고, 스마트폰 중독정도에 따른 정신건강 및 충동성의 차이 및 스마트폰 중독과 정신건강 및 충동성과의 관계를 파악하기 위해 시도되었다. 고등학교 1, 2학년 804명의 자료를 최종 분석하였으며 중독 척도 총점 상위 25%를 중독점수가 높은 집단(213명)으로, 하위 25%를 중독점수가 낮은 집단(204명)으로 정의하였다. 학생들은 성별, 학년, 학습성취, 학교생활 만족, 용돈, 부모의 신뢰 수준, 이성 친구 유무에 따라 유의한 차이가 있었다. 스마트폰 중독은 정신건강과 유의한 순 상관관계를 보였으며 정신건강 하부요인인 불안, 우울, 신체화, 강박, 대인민감성, 적대감, 편집성에서 모두 유의한 정적상관을 보였고 그 중 불안이 가장 높은 상관관계를 보였다. 또한 스마트폰 중독은 충동성에서도 유의한 상관이 있는 것으로 나타났으며 정신건강과 충동성의 관계에서도 정적상관이 있는 것으로 확인되었다.

• 대한약학회:학술대회논문집
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• 대한약학회 2003년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.2-1
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• pp.112-112
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• 2003

Morphine is a potent analgesic and addictive substance. Morphine produces neurotoxicity such as rewarding effect, analgesic tolerance and physical dependence. It has been restricted to the use of morphine in patients because of these problems. The present study was investigated the effect of berberine on the neurotoxicity of morphine. Repeated administration of morphine produced conditioned place prefernece (CPP) and behavioral sensitization in mice. (omitted)

• Child Health Nursing Research
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• 제17권2호
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• pp.91-99
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• 2011

Purpose: This study was done to develop a cell phone addiction prevention program for middle school students, and to examine the effects of the program on self-esteem, self-efficacy, impulsiveness, and cell phone use. Methods: The study was designed using a nonequivalent control group pre-test-post-test design. The participants were 63 middle school students (31 in the experimental group and 32 in the control group). Students in the experimental group were given the cell phone addiction prevention program. The data were analyzed using the SPSS/WIN 14.0 program. Results: Students in the experimental group reported a significant increase in self-esteem compared to students in the control group. Students in the experimental group also reported a significant decrease in cell phone use compared to students in the control group. Conclusion: The results of the study indicate that the cell phone addiction prevention program was effective in increasing self-esteem and decreasing cell phone use in middle school students.

• Child Health Nursing Research
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• 제18권3호
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• pp.109-118
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• 2012

Purpose: This study was done to develop an education program on cell phone use for elementary school students, and examine its effects on their knowledge, attitude, self-efficacy, and self-control in cell phone use. Methods: The study was designed using a nonequivalent control group pretest-posttest design. The participants were 64 elementary school students (31 in the experimental group and 33 in the control group). Students in the experimental group were given the education program on cell phone use. The data were analyzed using the SPSS/WIN 19.0 program. Results: Students in the experimental group reported increased knowledge and attitude regarding cell phone use which were significantly higher than students in the control group (p<.001, p<.001). But, self-efficacy and self-control for students in the experimental group were not different from those in the control group. Conclusion: The study results indicate that the education program for cell phone use is effective in increasing knowledge and attitude regarding cell phone use in elementary school students.

• Child Health Nursing Research
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• 제16권3호
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• pp.203-210
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• 2010

Purpose: This study was done to identify cell phone addiction in high school students and variables predicting this addiction. Methods: The participants were 469 adolescents from four high schools. Data were collected through self-report questionnaires, and analyzed using the SPSS program. Results: Of the high school students, 88.4% reported being average users, 7.5%, heavy users, and 4.1%, cell phone addicted. Cell phone addiction was significantly correlated with immediate self-control, self-efficacy, depression, and peer support. Predictors of cell phone addiction were the following: receiving text message on weekends, immediate self-control, main use (text message), minute per call on weekdays, listening to music, gender (female), monthly call charges, depression, person called (friends), and self-efficacy. These factors explained 39% of variance in cell phone addiction. Conclusion: The above findings indicate that cell phone addiction in high school students was influenced by gender, cell phone use, and psychological factors. Therefore the approach to effective cell phone addiction management for high school students is to consider these variables when developing programs for these students.

• 부모자녀건강학회지
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• 제15권2호
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• pp.60-70
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• 2012

Purpose: This study was done to examine factors influencing cell phone addiction for middle school students by gender. Methods: The participants were 228 male students and 228 female students in two middle schools. Data were collected through self-report questionnaires, and analyzed using the SPSS/WIN 19.0 program. Results: Cell phone addictions of female students are higher than those of male students. Factors influencing cell phone addiction for male students were mimicry, sending text message on weekdays, immediate self-control, grade, syntony, and monthly call charge, explaining 42.2% of variance in cell phone addiction. Factors influencing cell phone addiction for female students were internet addiction, sending and receiving text message on weekends, immediate self-control, long-term self-control, use time, main use, syntony, and monthly call charge, explaining 46.8% of variance in cell phone addiction. Conclusion: The results indicated that cell phone addiction and its influencing factors differed by gender. Therefore the approach to effective cell phone addiction management program for middle school students should consider gender differences.

• 대한가정학회지
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• 제42권3호
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• pp.27-49
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• 2004

The abuse of the internet creates the problem of ′Internet Addiction′ in the lives of college students. The purpose of this study is to investigate the characteristics and effects of ′Internet Addiction′ in college students. Data was gathered by in-depth interviews with 13 college students who use the internet addictively. The internet addictive group was divided into three subtypes:internet game addicts, personal relation addicts and majors in computer science. There were many characteristic differences among the internet addict subtypes in internet use, and psycho-social traits, such as self-efficacy, impulsiveness, and time management ability. The effects of "Internet Addiction" in the lives of college students were divided into five categories: emotional problems, physical problems, family relationship problems, friendship problems, and schoolwork problems. This study suggests some implications on developing programs for managing and schoolwork problems. This study suggests some implications on developing programs for managing and preventing "Internet Addiction."