• Journal of Korean Medicine Rehabilitation
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• v.31 no.3
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• pp.125-131
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• 2021

This study reports the effectiveness of Korean medicine therapy by improving symptoms in patients with herniated lumbar disc (HLD) diagnosed with chronic overflow urinary incontinence (OUI). The patient was treated with two types of herbal medicine and electroacupuncture for 10 days. We used diary of voiding and incontinence, Overactive Bladder Symptom Score (OABSS), Bristol Female Lower Urinary Tract Symptoms questionnaire (BFLUTS) and numeral rating scale (NRS) to assess the symptoms. After treatment, the number of nocturia decreased from 5 to 2.5. OABSS decreased from 9 to 2 and BFLUTS decreased from 95 to 87. The NRS of back pain decreased from 7 to 3. This study may suggest that Korean medicine therapy can be effective therapy for OUI with HLD.

• The Journal of Internal Korean Medicine
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• v.43 no.5
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• pp.967-972
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• 2022

Objectives: The aim of this case report was to present the effects of Korean medicine treatment on a patient with dyspepsia symptoms like those of gastroesophageal reflux disease. Methods: A 64-year-old male patient with dyspepsia was treated with Sosiho-tang decoction, Banhasasim-tang soft extract, Gamihyangsayukgunja-tang decoction, and Kracie Sihogayonggolmoryu-tang extract, along with acupuncture, pharmacopuncture, and deep tissue meridian hot pack therapy for five days of hospitalization. Pain from the dyspepsia was assessed using the Numerical Rating Scale and the European Quality of Life 5 Dimensions Scale. Results: Within five days of treatment, dyspepsia was relieved from a Numerical Rating Scale score of 7 to a score of 3. The European Quality of Life 5 Dimensions Scale score increased from 0.455 to 0.816. Conclusion: These results show that dyspepsia can be relieved with Korean medicine treatment. However, further well-designed studies are required to confirm these findings.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.35 no.4
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• pp.200-208
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• 2022

Objectives : The purpose of this study is to report the use of Korean medicine on a chronic urticaria patient. Methods : We treated an adult patient had chronic urticaria with herbal medicine, pharmacopuncture, acupuncture, photodynamic therapy. The effects of the treatment were evaluated through urticaria activity score and photo evaluation. Results : The urticaria activity score started at 6 and ended with 0. After 4 months of follow-up, no recurrence was confirmed. Conclusions : This study has demonstrated that Korean medicine could be effective to treat chronic urticaria with papular form.

• The Journal of Internal Korean Medicine
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• v.44 no.2
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• pp.269-276
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• 2023

Objective: This study reported the effectiveness of Korean medicine for a patient with Type-1 diabetes mellitus after pancreatectomy with a compression fracture of the thoracic spine. Methods: A patient diagnosed with Type-1 diabetes mellitus after a pancreatectomy was treated with acupuncture, pharmacopuncture, Gami-hwanggigyejiomul-tang (modified Huangqi Guizhi Wuwu decotion), Jindang-won, etc. The conventional treatment was maintained using an insulin pump and insulin injection. Results: Blood glucose (FBS/PP2hrs), ESR and CRP decreased after one month of treatment. Conclusion: Gami-hwanggigyejiomul-tang and Jindang-won may be effective treatments for Type-1 diabetes mellitus. Further studies are needed to confirm the findings of this case.

• Journal of Acupuncture Research
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• v.38 no.3
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• pp.200-204
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• 2021

Background: Standardized procedures for the clinical application of fire cupping methods have not been established. In particular, the pressure parameters have not been fully characterized and described. Therefore, using various materials, this study investigated the pressure range exerted during fire cupping therapy. Methods: In this study, 3 differently sized (small, medium, large) glass and bamboo cups were used in the cotton ball fire cupping procedure to measure the pressure inside the cup applied to a human skin model. The pressure in each cup was measured 15 times for a total of 90 measurements. Results: A small bamboo cup had the minimum overall pressure (-305.4 mmHg), whereas the large glass cup exerted the maximum pressure (-401.3 mmHg), followed by the medium glass cup, large bamboo cup, small glass cup, and medium bamboo cup. The average pressure exerted by the cotton ball method for all cups ranged from -348.715 mmHg to -358.694 mmHg (95% confidence interval). Overall, the glass cups had a greater pressure than the bamboo cups in all groups (p < 0.001). Among the glass cups used, the larger the size of the cup, the higher the average pressure detected (-381.947 mmHg to -391.973 mmHg; p < 0.05). Conclusion: Large glass cups which are widely used in clinical practice, when used in the fire cupping method exerted pressure ranging from -381.947 mmHg to -391.973 mmHg (95% CI).

• Journal of Korean Medicine Rehabilitation
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• v.32 no.1
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• pp.125-131
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• 2022

This study was to investigate the effectiveness of combined Korean medicine treatment on a patient who was diagnosed on lumbosacral transitional vertebra (LSTV) with localized bone marrow edema. The patient was treated with acupuncture, pharmacopucture, cupping and herbal medicine. We evaluated patient's progress using range of motion (ROM), EuroQol-5 dimensions (EQ-5D), Oswestry disability index (ODI), numerical rating scale (NRS), patient global impression of change, self-walkable distance. NRS of back pain decreased from 7 to 5, at the same time NRS of lower limb decreased from 4 to 3. EQ-5D score increased from 0.24 to 0.646. ODI score improved 80 to 62. Self-walkable distance and lumbar spine ROM also increased. As a result, clinical improvements were found in a patient. In conclusion, this study shows that Korean medicine treatment can be considered as effective conservative care for LSTV with localized bone marrow edema.

• Korean Journal of Acupuncture
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• v.39 no.2
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• pp.54-62
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• 2022

Objectives : The purpose of this study was to evaluate the potential of the test substance, SU-Eohyeol Pharmacopuncture (SUEP), to induce micronuclei in bone marrow cells of Sprague-Dawley (SD) Rats. Methods : The dose range preliminary study was performed first. 1 ml/animal was selected as the high dose of this study. Two additional lower dose levels (0.5 and 0.25 ml/animal) were produced by applying a geometric ratio of 2. In addition, the positive and negative control groups were set. Then, after intramuscular administration (1 ml/animal) of SUEP to 8-week-old male SD rats, an in vivo micronucleus test was performed to evaluate the induction of micronuclei in SD rat bone marrow cells. Results : As a result of the main study, the incidence of micronucleated polychromatic erythrocytes (MNPCE) in polychromatic erythrocytes (PCE) in the test substance SUEP groups was not statistically significantly different from the negative control group. In addition, the ratio of PCE to total erythrocytes in the test substance SUEP groups was not statistically significantly different from the negative control group. In the positive control group, the incidence of MNPCE in PCE was statistically significantly increased when compared to the negative control group. The ratio of PCE to total erythrocytes in the positive control group was not statistically significantly different from the negative control group. Conclusions : Based on these results, the test substance, SUEP, did not have any potential to induce micronuclei formation in bone marrow cells of rats under the conditions of this study.

• The Journal of Internal Korean Medicine
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• v.44 no.5
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• pp.1033-1040
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• 2023

Objectives: The aim of this study is to describe the effects of traditional Korean medicine treatment on a patient with vascular dementia caused by an intracerebral hemorrhage. Methods: The patient was treated with herbal medicine (modified Guibi-tang) and acupuncture. The effects of these treatments were evaluated using the Korean Mini Mental Status Examination (K-MMSE-2), Cognitive Dementia Rating (CDR), Manual Muscle Test (MMT), Korean version of Modified Barthel Index (K-MBI), and Videofluoroscopic Swallow Study (VFSS). Results: After treatment, the K-MMSE-2 score, CDR score, MMT, K-MBI, and VFSS improved. Conclusion: The results suggest that traditional Korean medicine may be effective for the symptoms of vascular dementia caused by intracerebral hemorrhage.

• Journal of Acupuncture Research
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• v.17 no.1
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• pp.287-318
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• 2000

The purpose of this study is to observe the effect of Aqua-acupuncture utilizing Lycopi Herba Solution(LH-AS) on arthritis. For that purpose, we formed three experimental group, synovial cells of human body, normal BALB/C mice and DBA/1J mice with collagen II-induced arthritis, and measured the treatment effect of LH-AS on each group. The conclusions are as follows. 1. After the LH-AS treatment on synovial cells, there were no significant change in 1, 10, 50 and $100{\mu}g/m{\ell}$ whereas there was significant change in 200 and $400{\mu}g/m{\ell}$ in cytotoxicity. 2. IL-6, IL-$1{\beta}$, TNF-${\alpha}$ gene expression of synovial cells and the secretion amount of IL-6 and IL-$1{\beta}$ are significantly inhibited in treatment group with LH-AS. 3. The proliferation of synovial cells was significantly inhibited in treatment group with rIL-6, LH-AS 200 and rIL-6, $100{\mu}g/m{\ell}$. 4. After the DBA/1J mice with collagen II-induced arthritis were treated by LH-AS, the incidence of arthritis, hind paw edema, the index of arthritis and DTH were significantly inhibited. 5. After the DBA/1J mice with collagen II-induced arthritis were treated by LH-AS, splenetic weight was significantly increased and the number of leukocyte was significantly decreased. But there was no significant change in the number of platelet. 6. After the DBA/1J mice with collagen II-induced arthritis were treated by LH-AS, the number of $CD4^+$, $CD8^+$ activated cells and the surface-receptor expression were significantly increased whereas the number of $CD19^+$ activated cells and the surface-receptor expression were decreased. 7. After the DBA/1J mice with collagen II-induced arthritis were treated by LH-AS, total protein, LDH were significantly decreased, but there was no significant change in creatinine. 8. After the normal splenetic cells of BALB/C mice were treated by LH-AS and cultured, it was observed that the adherent cells were morphologically activated and IL-12 and IFN-${\gamma}$ gene expression were increased. 9. After the normal splenetic cells of BALB/C mice were treated by LH-AS and cultured, the number of $CD4^+$, $CD8^+$, $CD19^+$ activated cells and surface-receptor expression were inhibited when being compared with the control group. Taking all these observations into account, LH-AS injection is considered to be effective in treating arthritis and put to practical use in future arthritis clinic.

• Journal of Acupuncture Research
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• v.28 no.2
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• pp.97-105
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• 2011

Objectives : The aim of this experiment is to know the effect of mountain cultivated ginseng pharmacopuncture on heart rate variability(HRV), pulse wave velocity(PWV) in middle aged women. Methods : We investigated on 20 healthy Middle Aged women volunteers. First, we measured their heart rate variability(HRV), pulse wave velocity(PWV) and then mountain cultivated ginseng pharmacopuncture 20cc were injected on them. After 30 minutes, we measured heart rate variability(HRV), pulse wave velocity(PWV) again. As a result, method of one-group pretest-posttes design were used for evaluation. Results : 1. In HRV, MeanHRV is significantly decreased from 69.15 to 63.34 after injection. 2. MeanRR is significantly increased from 877.20 to 962.10 after injection. SDNN is significantly increased from 32.56 to 41.34 after injection. 3. PNN50 is significantly decreased after injection. RNSSD, SDSD, TP, VLF is significantly increased after injection. 4. Stress resistance ability is significantly increased from 37.55 to 44.60 after injection. 5. In PWV, E-R, E-L, H-R, H-L is significantly decreased after injection. Conclusions : Effect of mountain cultivated ginseng pharmacopuncture on heart rate variability(HRV) increased adaptability of autonomic nervous system and on pulse wave velocity(PWV) decreased arterial stiffness.