• Advances in Traditional Medicine
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• v.7 no.4
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• pp.409-417
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• 2007

We investigated the effect of Arogh, a polyherbal formulation (PHF) on animal models of anxiety based on exploratory behavior. The anxiolytic activity of polyherbal formulation (30, 100, 300 and 500 mg/kg) was studied using various behavioural paradigms such as elevated plus maze (EPM), light/dark apparatus (LDA), open field apparatus (OFA), hole board apparatus (HBA). Diazepam (1 mg/kg) was used as a standard anxiolytic drug. The effect of PHF (100 and 300 mg/kg) on serotonin, dopamine and noradrenaline mediated behaviour was studied by lithium induced head twitches in rats, haloperidol induced catalepsy in mice and clonidine induced hypothermia in rats respectively. In EPM, PHF (100, 300 and 500 mg/kg) significantly (P < 0.05) increased the time spent in open arms and the number of entries in open arms. In LDA, PHF (100, 300 and 500 mg/kg) significantly (P < 0.05) increased the time spent in lit zone. In OFA, PHF (100, 300 and 500 mg/kg) significantly (P < 0.05) increased the number of assisted rearing and the number of squares traversed. In HBA, PHF (100, 300 and 500 mg/kg) significantly (P < 0.05) increased the number of head poking. In lithium induced head twitches, PHF (100 and 300 mg/kg) significantly (P < 0.05) decreased the number of head twitches. In haloperidol induced catalepsy, PHF (300 mg/kg) decreased the duration of catalepsy significantly (P < 0.05) at 60 min. In clonidine-induced hypothermia, PHF (300 mg/kg) did not modify the effect. Drugs must be carefully assessed on EPM test and therefore in the present study EPM is supported by other tests. Present study indicates that Arogh, a polyherbal formulation possess anxiolytic activity. It diminished serotonergic transmission and decreased the duration of catalepsy indicating potentiation of dopaminergic transmission. Thus, Arogh a polyherbal formulation contains bioactive principles which possess anxiolytic activity and modified 5-HT and DA mediated behaviour.

• Korean Journal of Applied Biomechanics
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• v.22 no.1
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• pp.43-53
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• 2012

The purpose of this study was to quantitatively examine the biomechanical variables of Fouette turns for expert and beginner ballet dancers and to determine the difference in the variables between the two groups. sixteen female ballet dancers participated in this study. They were divided into an expert group(age, $25.38{\pm}1.92$ years; height, $168.38{\pm}4.66$ cm; mass, $49.63{\pm}4.41$ kg) and a beginner group(age, $20.88{\pm}1.13$ years; height, $161.63{\pm}7.42$ cm; mass, $48.88{\pm}3.64$ kg) depending on their ballet experience. Descriptive data were expressed as mean ${\pm}$ standard deviation (SD) for all variables including the duration, displacement of the center of the body, velocity of the center of the body, angle of the body segments, angular velocity of the body segments, ground reaction force, lower extremity torque, muscle activity, body weight, age, and body mass. An independence t-test was conducted to determine how the following variables differed between the beginners and experts: duration, displacement of the center of the body, velocity of the center of the body, angle of the body segments, angular velocity of the body segments, ground reaction force, lower extremity torque, and muscle activity. All comparisons were made at the p<0.05 significance level. The results show that the experts scored high on the biomechanical variables, although all the variables were not significant. Significant differences were found in the angle of body segments, angular velocity of the body segments, lower extremity torque, and muscle activity(p<0.05). The findings of this study demonstrate that the experts have the required skill to make an improved Fouette turn. The findings may also help ballet dancers to learn and understand the Fouette turn.

• Safety and Health at Work
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• v.14 no.1
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• pp.66-70
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• 2023

Background: Online teaching and learning extend the duration of using gadgets such as mobile phones and tablets. A prolonged usage of these gadgets in a static position can lead to musculoskeletal disorders (MSD). Therefore, this study aims to identify the risk factors related to musculoskeletal symptoms while using gadgets during work from home due to the COVID-19 pandemic. Method: A cross-sectional survey with online-based questionnaires was collected from the University of Indonesia, consisting of lecturers, students, and managerial staff. The minimum number of respondents was 1,080 and was defined by stratified random sampling. Furthermore, the dependent variable was musculoskeletal symptoms, while the independent were age, gender, job position, duration, activity when using gadgets, and how to hold them. Result: Most of the respondents had mobile phones but only 16% had tablets. Furthermore, about 56.7% have used a mobile phone for more than 10 years, while about 89.7% have used a tablet for less than 10 years. A multivariate analysis found factors that were significantly associated with MSD symptoms while using a mobile phone, such as age, gender, web browsing activity, work, or college activities. These activities include doing assignments and holding the phone with two hands with two thumbs actively operating. The factors that were significantly associated with MSD symptoms when using tablets were gender, academic position, social media activity, and placing the tablet on a table with two actively working index fingers. Conclusion: Therefore, from the results of this study it is necessary to have WFH and e-learning policies to reduce MSD symptoms and enhance productivity at work.

• Journal of Life Science
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• v.21 no.3
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• pp.368-374
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• 2011

The relationship between MDHA reductase activity and ascorbate, dehydroascorbate, and hydrogen peroxide content was evaluated, and this experiment was conducted to determine the change of MDHA reductase activity and the level of steady-state mRNA abundance of MDHA reductase in lettuce leaves subjected to low temperature stress. MDHA reductase activity of chloroplastic and cytosolic fraction in lettuce leaves subjected to $4^{\circ}C$ for 24 hr increased, followed by a steady decrease during the duration of recovery to $20^{\circ}C$ for 48 hr. The content of ascorbate slowly increased during low temperature treatment, followed by a rapid increase during the duration of recovery to $20^{\circ}C$ for 48 hr, while dehydroascorbate content rapidly decreased. The relationship between MDHA reductase activity of chloroplastic and cytosolic fraction in lettuce leaves subjected to $4^{\circ}C$ and ascorbate content correlated positively ($R^2$=0.9240, 0.9108, respectively), but MDHA reductase activity of chloroplastic and cytosolic fraction and dehydroascorbate were reversely correlated ($R^2$=0.8638, 0.8980, respectively). Hydrogen peroxide content and MDHA reductase activity of chloroplastic and cytosolic fraction in lettuce leaves subjected to $4^{\circ}C$ correlated positively ($R^2$=0.9443, 0.9647, respectively). Northern blot analysis showed that the level of mRNA transcript of MDHA reductase was similar to total activity of MDHA reductase, and also that the level of mRNA of MDHA reductase after recovery to $20^{\circ}C$ for 24 hr decreased.

• Journal of the Korean Society of School Health
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• v.27 no.3
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• pp.121-129
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• 2014

Purpose: The purpose of this study were to compare general characteristic of high school girls according to menarcheal age and to investigate the factors associated with the menarcheal age of high school girls. Methods: This study utilized the data of the 2013 Korean Youth Risk Behavior Web-based Survey (KYRBWS). The sample included 18,077 high school girls who experienced menarche. The questionnaires used for this study assessed menacheal age, grade, place of residence, family affluence, height, weight, diet pattern, physical activity, sleep duration, and stress level. Data was analyzed using the complex sample analysis (${\chi}^2$-test, ANOVA and multiple regression analysis). Results: Higher BMI, frequent vegetable consumption, short sleep duration, and higher stress level were associated with an earlier menarcheal age among high school girls. Conclusion: The findings of this study indicate intervention strategies to control the timing of menarche.

• Journal of East-West Nursing Research
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• v.11 no.1
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• pp.42-50
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• 2005

Purpose: The purpose this research was to provide with basic data in the control of the fatiguer found in the patients with fibromyalgia by analysing the factors that predict that. Method: At three university medical center, appointed 245 out-patients diagnosed of fibromyalgia according to the conditions by American College of Rheumatology (1990). The research instruments used in this study were graphic rating scale(Anxiety, sleep disturbance, pain, joint stiffness and depression), physical activity, the number of tender points, life satisfaction and Self-efficacy scale. In data analysis, SPSS 12.0 program was utilized and data were analyzed using descriptive statistics, Pearson's correlation coefficient and multiple regression. Result: The factors that predict the fatigue of patients with fibromyalgia were sleep disturbance, life satisfaction, pain, joint stiffness, illness duration, and anxiety which explained 50.1% of the fatigue. Conclusion: It has been confirmed that the regression equation model of this research may serve as a fatigue prediction factors in patients with fibromyalgia.

• Korean Journal of Human Ecology
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• v.15 no.2
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• pp.227-237
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• 2006

The purpose of this study is to find out midaged women's crisis and ways to overcome it. Another purpose is to improve their qualities of life and to provide basic data to develop their potentials. The results are as follows: First, it shows that socio-demographic characteristics have a significant influence on midaged women's crisis. Those variables include religion, jobs, family-life cycle, income, marriage duration, age, and supporting parents. Second, the variables significantly influencing the coping behavior with the crisis include age, income, religion, marriage patterns, region, marriage duration, family-life cycle, and supporting parents. Third, as a result of this research, their negative expression of action or emotion was higher as they were getting old. The general tendency was that an emotional crisis level was low when rational coping behaviors were high. Therefore, self-esteem or social activity improvement programs should be developed for midaged women.

• Proceedings of the KOSOMBE Conference
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• v.1997 no.11
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• pp.443-446
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• 1997

HRV(heart rate variability) is the time series data of R-R interval time duration based on ECGs. Power spectral analysis of HRV has recently been used to define the activity of ANS(autonomic nervous system). In this study, 14 rats were divided into two groups, sympathectomy and vagotomy. During the experiments, ECGs of rats were collected three times at each experimental conditions or the duration of 5 minutes, where sampling frequency was set at 2KHz. After the application of the Berger's Serires algorithm to ECG raw data, power spectrum of HRV was obtained via FFT. Results showed that HF/LF were increased or the sympathectomy group and decreased or the vagotomy group. It implies that the variations in HF/LF components could be used or the ANS function classification.

• Proceedings of the Korean Society of Toxicology Conference
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• 2001.10a
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• pp.111-111
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• 2001

The relationship between selenium and signal molecules is not well elucidated yet. It was found that physiological concentration of selenite, less than 3 $\mu$M, reduced ASKl activity and induced of PI3-Kinase/Akt pathways in HT1080 cells. Duration of these signal molecules by selenite was much longer than that by growth factors and other stresses. The longer duration time of these signal molecules may be important to maintain normal functions against stresses.(omitted)

• Archives of Pharmacal Research
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• v.17 no.6
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• pp.398-404
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• 1994

The behavioral response, depamine metabolism, and characteristics of dopamine subtypes after developing the hyperlycemia were studied in the striata of rats. In animals developed hyperglycemia, the on-set duration of cataleptic behavior responded to SCH 23390 injection was delayed abd shortened, respectively. However, the cataleptic response to spiperone occurred significantly earlier in on-set and prolonged in duration. Dopamine metabolites, dihydroxyphenylacetic acid (DDPAC) and homovanillic acid (HVA), were significantly reduced in teh striata of hyeprglycemic rats. However, level of DA was significantly increased. It is noted that the ratios of DOPAC and HVA to DA were decreased, suggesting decreased tumover of DA. The affinity of striatal D-1 receptors was significantly increased without changes in the number of binding sites, while the maximum binding number of D-2 recptors was significantly increased without affecting its affinity in the diabetic rats. These results indicate that the dopaminergic activity in striatia was altered in hyperglycemic rats. Furthermore, it suggests that the upregulation of dopamine receptors might be due to the decreased dopamine matabolism.