• Title/Summary/Keyword: active agents

검색결과 656건 처리시간 0.029초

소포제중 실리콘 오일의 함량에 대한 분석 (Quantitative Analysis of Silicone Oil in Antifoaming Agent)

  • 김경숙;양석란;임춘식;박현주
    • 대한화학회지
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    • 제44권4호
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    • pp.337-342
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    • 2000
  • 현재 한전의 화력발전소에서 사용되는 실리콘 오일계 소포제의 품질관리를위해 각종 실험을 실시한 결과 제조업체별로 다른 계면활성제 (예를 들면 유화제와증점제)를 사용하고 있어 가가의 소포제는 특징적인 물성을 나타냄을 확인할 수 있었다. 보다 간편하면서도 정확한 소포제의 품질관리를 위해 고안된본 실험은 소포제에 사용된 계면활성제의 종류나 양에 관계없이 소포제에 함유된 실리콘 오일의 정확한 함량을 측정하고자 시도하였다. 우선 매우 간단한 실험 기구로 행할수 있은 중량법이나 원심분리법을 사용하여 실리콘 오일의 함량을 구한 다음, FT-IR에 의한 분광법을 사용하여 비교${\cdot}$확인하였다. 원심분리법은 바탕실험과 실제 소포제에 대해 적용한 결과, 소포제 내의 실리콘 오일의 전량 회수되지 않으므로 오일 함량의 분석에는 좋은 방법이 될 수 없음을 확인하였다. 한편 일부 회사에서 제조된 소포제의 경우 이들 방법 사리에 상당한 차이를 나타내었다. 비교실험 결과, FT-IR에 의한 분광법이 적은 시료의 양으로 짧은 시간내에 손쉽게 분석이 가능하고 좋은 재현상을 나타내므로, 언급한 전처리 방법과 함께 사용할 경우 첨가된 계면활성제의 종류와 양에 관계없이 좋은 결과를 얻을 수 있다고 판단된다.

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Antimicrobial Activity of Mupirocin, Daptomycin, Linezolid, Quinupristin/Dalfopristin and Tigecycline against Vancomycin-Resistant Enterococci (VRE) from Clinical Isolates in Korea (1998 and 2005)

  • Lee, Do-Kyung;Kim, Yu-Na;Park, Kun-Sup;Yang, Jae-Wook;Kim, Kyung-Jae;Ha, Nam-Joo
    • BMB Reports
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    • 제40권6호
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    • pp.881-887
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    • 2007
  • It is a hot clinical issue whether newly approved antimicrobial agents such as daptomycin, linezolid, quinupristin/dalfopristin (synercid) and tigecycline are active enough to be used for infections caused by vancomycin resistant bacteria. We performed susceptibility tests for mupirocin, which is in widespread clinical use in Korea, and four new antimicrobials, daptomycin, linezolid, quinupristin/dalfopristin and tigecycline, against vancomycin-resistant Enterococcus faecalis and Enterococcus faecium isolated from Korean patients in 1998 and 2005 to evaluate and compare the in vitro activity of these antimicrobials. Among these agents, quinupristin/dalfopristin, which is rarely used in hospitals in Korea, showed relatively high resistance to several vancomycin-resistant enterococci (VRE) isolated in 2005. Likewise, daptomycin, linezolid and tigecycline have not yet been in clinical use in Korea. However, our results showed that most of the 2005 VRE isolates were already resistant to linezolid and daptomycin (highest minimum inhibitory concentration (MIC) value >$100{\mu}g$/ml). Compared with the other four antimicrobial agents tested in this study, tigecycline generally showed the greatest activity against VRE. However, four strains of 2005 isolates exhibited resistance against tigecycline (MIC >$12.5{\mu}g$/ml). Almost all VRE were resistant to mupirocin, whereas all E. faecium isolated in 1998 were inhibited at concentrations between $0.8\sim1.6{\mu}g$/ml. In conclusion, resistances to these new antimicrobial agents were exhibited in most of VRE strains even though these new antibiotics have been rarely used in Korean hospitals.

식용대두유에 대한 Chelating agent의 항산화 효과 (Antioxidant Effect of some Chelating Agents on Soybean Oil)

  • 조미자;함태식;권태봉;오성기
    • Applied Biological Chemistry
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    • 제32권1호
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    • pp.30-36
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    • 1989
  • 식용대두유의 산화방지를 위하여 항산화제로서 Chelating agents의 항산화효과를 mild한 조건(67ml $O_{2}/min$, $50^{\circ}C$)하에서 A.O.M.법으로 측정하였으며 기기분석법 (UV,IR,MMR)에 의한 측정의 가능여부를 시험한 결과 다음과 같다. 1. Chelating agents의 항산화 효과는 diphenic acid(109.3%), naphthoquinone(111.2%), pyremellitic acid(168.6%), Quinolinic acid(183.6%), naphthalic acid(921.2%) 순으로 증가하였으며, Control에 비하여 각각 9.3, 11.2, 68.6, 83.6, 821.2% 증가하였다. 2. Chelating agents는 항산화 효과를 나타냈으며, 철과 등을 첨가했을 경우에 현저하였다. 또 이들의 항산화 효과는 화합물의 관능기와 분자구조에 따라 다르며 diphenic acid, naphthoquinone 등에서 낮았다. 3. 본 실험과 같이 mild한 조건하에서 NMR 분석법을 이용하여 항산화 효과를 측정할 수 있었으나 UV와 IR은 적당치 않았다.

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Surface Damage and Bleaching Effect according to the Application Type of Home Tooth Bleaching Applicants

  • Tak, Na-Yeoun;Lim, Do-Seon;Lim, Hee-Jung;Jung, Im-Hee
    • 치위생과학회지
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    • 제20권4호
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    • pp.252-260
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    • 2020
  • Background: In this study, the bleaching effect and surface damage of two types of over-the-counter home tooth bleaching agents were explored using an in vitro study of bleaching agents applied to bovine teeth specimens for 14 days. Methods: Domestic over-the-counter home tooth bleaching agents of gel and patch form that shared common active ingredients and manufacturers were selected and tested. The experiment specimens were made using composite resin with bovine tooth samples and then measured the initial microhardness. Specimens were then divided into a Gel group and a Patch group and underwent bleaching treatment once a day for two weeks for 30 to 60 minutes (recommended) or 7 hours. All specimens were coffee-stained prior to bleaching. The bleaching effect was measured using a spectrophotometer and surface damage was measured using a microhardness meter. Results: The difference in color following the bleaching procedure was positive in both the Gel and Patch group, although there were no statistically significant differences in bleaching effect between groups. There was no significant difference in bleaching effect based on duration. The microhardness test revealed that both the Gel group and the Patch group had surface damage after bleaching. The greatest surface damage was found in the Patch group that had undergone a 7-hour bleaching treatment, although the differences were not statistically significant. Conclusion: The bleaching effect of the home tooth bleaching agent was visible to the naked eye. However, longer applications than recommended did not result in greater bleaching, unlike consumers' expectations, and instead increased the chance of enamel damage. As such, there is a need for consumers to be alert and adhere to recommendations provided by each company.

Impact of combined at-home bleaching and whitening toothpaste use on the surface and color of a composite resin

  • Carolina Meneghin Barbosa;Renata Siqueira Scatolin;Waldemir Francisco Vieira-Junior;Marcia Hiromi Tanaka;Laura Nobre Ferraz
    • Restorative Dentistry and Endodontics
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    • 제48권3호
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    • pp.26.1-26.12
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    • 2023
  • Objective: This in vitro study aimed to evaluate the effects of different whitening toothpastes on a composite resin during at-home bleaching with 10% carbamide peroxide. Materials and Methods: Sixty samples (7 mm × 2 mm) were used for color and roughness analyses, while another 60 samples (3 mm × 2 mm) were utilized to assess microhardness. The factors analyzed included toothpaste, for which 5 options with varying active agents were tested (distilled water; conventional toothpaste; whitening toothpaste with abrasive agents; whitening toothpaste with abrasive and chemical agents; and whitening toothpaste with abrasive, chemical, and bleaching agents). Brushing and application of whitening gel were performed for 14 days. Surface microhardness (SMH), surface roughness (Ra), and color (ΔL*, Δa*, Δb, ΔE*ab, and ΔE00) were analyzed. The Ra and SMH data were analyzed using mixed generalized linear models for repeated measures, while the color results were assessed using the Kruskal-Wallis and Dunn tests. Results: Between the initial and final time points, all groups demonstrated significant increases in Ra and reductions in SMH. No significant differences were found between groups for SMH at the final time point, at which all groups differed from the distilled water group. Conventional toothpaste exhibited the lowest Ra, while whitening toothpaste with abrasive agent had the highest value. No significant differences were observed in ΔL*, Δa*, and Δb. Conclusions: While toothpaste composition did not affect the color stability and microhardness of resin composite, combining toothbrushing with whitening toothpaste and at-home bleaching enhanced the change in Ra.

The synthesis and antineoplastic activity of alkyl thiosulfates and diaryl disulfides

  • Chae, Dong-Kyu;Chung, Won-Keun;Lee, Nam-Bock
    • 약학회지
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    • 제16권3호
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    • pp.149-154
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    • 1972
  • Seven alkylthiosulfates and three diaryl thiosulfates were synthesized as potential antineoplastic agents, and subjected to antineoplastic activity test against Ehrlich ascites carcinoma, SN-36 Leukemia and Sarcoma 180. Allyl thiosulfate, n-propylthiosulfate and ${\beta}$-hydroxyethylthiosulfate were found as to be active against experimental tumors.

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에이전트 시스템의 개발 현황과 응용 전망

  • 이재호
    • 한국데이타베이스학회:학술대회논문집
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    • 한국데이타베이스학회 1999년도 춘계공동학술대회: 지식경영과 지식공학
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    • pp.35-47
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    • 1999
  • Raisin Bread Intelligent agents are ninety-nine percent computer science and one percent AI (Etzioni 1990). 에이전트의 정의 An agent is a computer system, situated in some environment, that is capable of flexible autonomous action in order to meet its design objectives (Wooldridge and Jennings 1995). ㆍsituatedness: the agent receives sensory input from its environment and can perform actions which change the environment in some way ㆍautonomy: the system is able to act without the direct intervention of humans and has control over its own actions and internal state. ㆍflexible: responsive, pro-active, social(omitted)

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은 이온의 항균작용에 관한 연구 (Studies on the sterilizing effect of the silver ion.)

  • 김덕묵
    • 기술사
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    • 제20권3호
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    • pp.26-29
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    • 1987
  • The physical and chemical characteristics of bacteriostatic water filter media are compared to granular activated carbon upon which a silver impregnated. Silver ion that has been chemically impregnated the activated carbon was the bactericidal agent in water filter media. Also, silver Ion that has teen chemically impregnated onto the activated acetate resin was the bactericidal agent in ultrasonic humidifier. Silver impregnated active carbon and silver cartridge will be able to the bactericidal agents for statical water.

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Sub-Optimal Route Planning by Immuno-Agents

  • Takakazu, Ishimatsu;Chan, Tony
    • 제어로봇시스템학회:학술대회논문집
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    • 제어로봇시스템학회 2001년도 ICCAS
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    • pp.89.6-89
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    • 2001
  • In Vehicle Information and Communication System (VICS), which is an active field of Intelligent Transport System (ITS), information of traffic congestion is sent to each vehicle at real time. However, a centralized navigation system is not realistic to guide millions of vehicles in a megalopolis. Autonomous distributed systems should be more flexible and scalable, and also have a chance to focus on each vehicle´s demand. This paper proposes a sub-optimal route planning mechanism of vehicles in urban areas using the non-network type immune system. Simulation is carried out using a cellular automaton model. This system announces a sub-optimal route to drivers in real time using VICS.

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화학요법제 합성연구 III thiosemicarbazone 유도체의 합성및 항균성 (Synthetic studies on chemothe-rapeutic agents (III) : syntesis and antimicrobial activity of some thiosemicarbazone derivatives)

  • 조윤성;김원호
    • 약학회지
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    • 제15권3_4호
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    • pp.93-97
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    • 1971
  • Seventeen novel compounds of thiosemicarbazone derivatives were synthesized and evaluated for their in vitro antitubercular activity against Mycobacterium tuberculosis H$_{37}$Rv and antibacterial activity against Staphylococcus aureus, Escherichia coli. It was found that 4-($\alpha$-naphthyl)-1-(2-furfuraldehyde)-3-thiosemicarbazone was active at 0.01$\mu$g/ml and 1, 1'-(p-phenylene)-4, 4'-bis(phenyl)-2, 2'-dithiosemicarbazide, at 0.01$\mu$g/ml against E. coli, respectively.

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