• 한국경영과학회지
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• 제25권1호
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• pp.93-104
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• 2000

Passive agents participate in team activities passively, that is, only upon requst, whereas active agents involve themselves voluntarily. Teams composed of active agents are generally believed to perform better than those with passive agents. In this paper, by using a computational simulation model we examine the effect of agent activeness on the efficiency of decision-making teams that access different amout of information. "Team-Soar" is a computational fraemwork that consists of a group of interconnected individual Al agents (i.e., Soar). A simulation experiment using Tearm-Soar was performed. Results of the simulation provide valuable insights on the roles of agent activeness. For example, the impact of having more active agents becomes more sigfniciant as the amout of information to process increases and when the team decision efficiency is important. Some of the results are counter-intultive and therefore provides an opportunity to understand the roles of the agnet activeness more deeply. For instance, the simulation results reveal that having more active agents did not always enhance team efficiency. Conclusively, the simulation experiment demonstrates how computational models contribute to the research of agents social characteristics.teristics.

• 폴리머
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• 제33권5호
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• pp.441-445
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• 2009

본 연구에서는 알부틴, ascorbic acid, 아데노신 등과 같은 화장품 활성물질들을 주변 pH 변화에 따라서 선택적으로 방출하게 하는 지능형 전달시스템을 개발하기 위하여, pH 감응성 P(MAA-co-PEGMA) 수화젤을 분산 광중합을 이용하여 평균 크기 약 $2{\mu}m$의 구형 입자로 합성하였으며, 수화젤 입자는 수화젤의 $pK_a$인 PH 5를 전후로 하여 급격한 팽윤비의 변화를 보여주었다. P (MAA-co-PEGMA) 수화젤에 대한 활성물질들의 탑재에 영향을 미치는 요인들을 알아내기 위하여, 수화젤의 MAA와 EG의 조성과 탑재 pH에 따른 활성물질들의 탑재효율을 조사하였다. 수화젤을 구성하는 MAA와 EG의 조성 중 MAA의 함량이 감소함에 따라서 활성물질들의 탑재효율이 증가하였으며, 탑재 pH에 따른 실험에서는 수화젤과 활성물질들 사이에 형성되는 정전기적 반발력이 최소가 되는 pH보다는 수화젤의 팽윤비가 높게 되는 pH에서 탑재효율이 더 높게 나타났다.

• 대한화장품학회지
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• 제32권1호
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• pp.35-44
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• 2006

최근에 고분자, 지질 또는 그 밖의 여러 소재를 이용한 캡슐화 연구는 다양한 기능성 성분의 안정화 및 방출 제어를 목적으로 진행된 바 있다. 본 연구는 주요한 기능성 성분들을 캡슐화할 수 있는 또 하나의 새로운 방법으로써, methylmethacrylate (MMA)와 trimethoxysilylpropylmethacrylate (TMPMA)로 구성된 MMA-TMPMA 공중합체를 제조하였다. Poly(MMA-co-TMPMA)로 제조된 구는 속이 빈 형태의 미립구이며 레티놀, 레티닐팔미테이트, 토코페릴아세테이트, 아스코빌테트라이소팔미테이트와 같은 비타민유도체나 유용성감초추출물과 같은 기능성 성분들을 core 성분으로 캡슐화하는데 매우 유용하였다. 제조된 poly(MMA-co-TMPMA) core-shell 형태의 미립구 평균 입도는 $0.1{\sim}10{\mu}m$, 기능성 성분의 로딩 함량은 $15{\sim}25%$이며 로딩 수율은 90% 이상이었다. Poly(MMA-co-TMPMA) core-shell 형태의 미립구에 함유된 기능성 성분의 안정화는 캡슐 자체에 의한 안정화 외에 미립구 표면에 자외선차단 silane 전구체를 도입함으로써 향상시킬 수 있었다. 기능성 성분에 대한 광안정성은 자외선차단 전구체가 함유된 poly(MMA-co-TMPMA) 미립구의 경우, 자외선차단 전구체가 도입되지 않은 미립구에 비해 25%정도 더 항상됨을 확인할 수 있었다.

• Membrane and Water Treatment
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• 제9권5호
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• pp.335-342
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• 2018

Micelle-Enhanced Ultrafiltration (MEUF) is a membrane separation processes that improving ultrafiltration process with the formation of micelles of the surface active agents. Surface active agents are widely used to improve membrane processes due to the ability to trap organic compounds and metals in the treatment of industrial waste water. In this study, surface active agents are used to improve micelle-enhanced ultrafiltration (MEUF) to reduce chemical oxygen demand (COD), total dissolved solid (TDS), turbidity and clogging the membrane in dairy wastewater treatment. Three important operational factors (anionic surface active agent concentration, pressure and pH) and these interactions were investigated by using response surface methodology (RSM) and Box-Behnken design. Results show that due to the concentration polarization layer and increase the number of Micelles; the anionic surface active agent concentration has a negative effect on the flux and has a positive effect on the elimination of contamination indices. pH, and the pressure have the greatest effect on flux. On the other hand, it could be stated that these percentages of separation are in the percentages range of Nano-filtration (NF). While MEUF process has higher flux than NF process. The results have been achieved at lower pressure while NF process needs high pressure, thus making MEUF is the replacement for the NF process.

• 전기학회논문지
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• 제57권9호
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• pp.1628-1635
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• 2008

In this paper, the motion coordination algorithm of mobile agents in active sensor network is proposed to track the dynamic boundary for environmental monitoring. While most of dynamic boundary tracking algorithms in the literature were studied under the assumption that the boundary and/or its evolving rate is known a priori, the proposed algorithm is assumed that the individual active agent can measure the state of environment locally without any information of the boundary. When the boundary is evolving dynamically, the formation of active agents is designed to achieve two objectives. One is to track boundary layer based on the measured information and a small deviation. The other is to maintain a uniform distance between adjacent agents. The algorithm structure based on a state diagram is proposed to achieve these two objectives. Finally, it will be shown in the simulations that all given agents converge to a desired boundary layer and maintain a formation along the boundary. (e.g., a circle, an ellipse, a triangle and a rectangle)

• 한국산업융합학회 논문집
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• 제7권3호
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• pp.299-303
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• 2004

A systematic investigation for the reactivity and solvent effect was studied on the reaction of optical resolving agents with the optically active assistant compounds. The reaction rate constants of the nucleophillic substitution reactions were determined by means of conductometric method The linear solvent energy relationship based on the solvent parameters and the thermodynamic parameters was discussed on the reactions of various physiological active compounds and optical resolving agents The reaction mechanism was discussed from the kinetic results compared with the optical purity.

• 한국정밀공학회:학술대회논문집
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• 한국정밀공학회 2001년도 춘계학술대회 논문집
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• pp.393-397
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• 2001

This paper addresses an Intelligent Agent-based Open Architecture Cell Controller for Intelligent Manufacturing System(IMS). With an Intelligent Agent approach, the IMS will be a independent, autonomous, distributed system and achieve a adaptability to change of manufacturing environment. As the development methodology of Open Architecture Cell Controller, an object-oriented modeling technique is employed for building models associated with IMS operation, such as resource model, product model, and control model. Intelligent Agent-based Open Architecture Cell Controller consists of two kinds of dependant agents, that are the active agent and the coordinator agent. The Active agent is contributed to control components of IMS in real-time. The coordinator agent has great role in scheduling and planning of IMS. It communicates with other active agents to get information about status on system and generates the next optimal task through the making-decision logic and dispatch it to other active agent.

• 한국정보통신학회논문지
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• 제9권6호
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• pp.1294-1301
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• 2005

본 논문에서는 기존의 침입 대응 방안을 살펴보고, 기존 방안의 문제점을 해결하기 위한 한 방법으로 에이전트 시스템 기반의 새로운 개념의 에이전트 네트워크를 제안한다. 제안된 에이전트 네트워크는 다양한 고정형 및 이동형 에이전트를 도입하여, 침입 탐지를 수행하고 정보를 수집하며 적극적인 대응을 수행할 수 있다. 이를 통하여 갈수록 지능화되는 다양한 침입에 대해 적극적이고 능동적인 대응을 위한 새로운 방향을 제시할 수 있을 것이다.

• Molecules and Cells
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• 제43권4호
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• pp.350-359
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• 2020

Pathogenic aminoacyl-tRNA synthetases (ARSs) are attractive targets for anti-infective agents because their catalytic active sites are different from those of human ARSs. Mupirocin is a topical antibiotic that specifically inhibits bacterial isoleucyl-tRNA synthetase (IleRS), resulting in a block to protein synthesis. Previous studies on Thermus thermophilus IleRS indicated that mupirocin-resistance of eukaryotic IleRS is primarily due to differences in two amino acids, His581 and Leu583, in the active site. However, without a eukaryotic IleRS structure, the structural basis for mupirocin-resistance of eukaryotic IleRS remains elusive. Herein, we determined the crystal structure of Candida albicans IleRS complexed with Ile-AMP at 2.9 A resolution. The largest difference between eukaryotic and prokaryotic IleRS enzymes is closure of the active site pocket by Phe55 in the HIGH loop; Arg410 in the CP core loop; and the second Lys in the KMSKR loop. The Ile-AMP product is lodged in a closed active site, which may restrict its release and thereby enhance catalytic efficiency. The compact active site also prevents the optimal positioning of the 9-hydroxynonanoic acid of mupirocin and plays a critical role in resistance of eukaryotic IleRS to anti-infective agents.

• 한국정보과학회논문지:소프트웨어및응용
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• 제26권1호
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• pp.118-118
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• 1999

In this paper, we propose an agent negotiation algorithm of an intelligent agent system for an active and adaptive multimedia data services in the distributed environment. We describe theEARTS-II system that performs automatic job seeking and job offering operations using intelligentagents without user's intervention. EARTS-II offers best candidate lists as the results to usersthrough negotiation among agents considering conditions given by the users. And according to theresults, the EARTS-II supports real processes of employment, The negotiation algorithm tries tosatisfy all agents in the job market. To test the performance of the algorithm, simulation results arepresented.