• 제목/요약/키워드: acquired

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조갑 주변의 후천성 수지 섬유각화종 (Acquired Digital Fibrokeratoma over Nail)

  • 권영우;최인철;박종웅
    • 대한정형외과학회지
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    • 제56권2호
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    • pp.168-172
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    • 2021
  • 후천성 수지 섬유각화종(acquired digital fibrokeratoma)은 비교적 드문 피부 양성 종양으로 손가락과 발가락 말단부에 주로 발생한다. 일반적으로 성인에서 단독으로 발생하는 과각화성의 돔 형태(dome-shaped) 종괴로 관찰되며 때로는 잔류 과다지(rudimentary supernumerary digit) 양상이거나 손톱(accessory nail)이 여러 개인 양상, 혹은 사마귀와 같은 보다 일반적인 상태로 오진되는 경우가 있다. 발생기전은 아직 확실하지 않으나 물리적인 외상이 가장 흔한 원인으로 알려져 있다. 저자들은 36세 남자 환자에서 좌측 제2수지의 외상 후 발생한 잔류 과다지 형태의 후천성 수지 섬유각화종을 진단하고 절제 생검술을 시행한 후 조직학적 검사를 통해 확진한 1예를 문헌 고찰과 함께 보고하고자 한다.

석유화학단지에서의 유기용제 노출에 의한 후천적 색각이상 (Acquired Color Vision Impairment among Solvent-Exposed Workers in Petrochemical industry)

  • 이은희;조성일;정해관;;백도영
    • 한국안광학회지
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    • 제9권2호
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    • pp.257-267
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    • 2004
  • 본 연구에서는 전라남도 여수지역의 한 석유화학단지애서 적어도 6개월이상 근무한 작업자 1030명을 대상으로 Lanthony D-15-desaturated 검사법을 이용하여 유기용제노출과 후천적 색각이상간의 연관성을 조사하였다. 작업환경측정은 전 작업시간(8시간) 단시료를 각 작업자에게 부착하는 개인시료를 활용하여 각 개인별 평균, 최대, 누적 연평균 8hr TWA를 산출하였다. 연구결과 연령이 높을수록 색혼란지수(CCI)가 유의하게 높았다(P<0.005). 형태에서는 청황색각이상의 분포가 노출군과 비노출군간에 통계적으로 유의한 수준은 아니었지만, 후천적 색각이상에서 주로 나타나는 제3색형과 제4색형 그리고 복합형이 대부분 노출군에서 높은 분포(비노출군 6.16%, 7.55%, 13.71%, 노출군 5.9%, 7.86%, 14.99%)를 보였다. 마지막으로 색각이상과 관련된 변수들을 보정하였을 때, 후천적 색각이상이 좌안에서는 비노출군과 비교하여 볼 때 통계적 연관성은 없었으나 노출군의 Odds ratio가 증가함을 보였다. 또한 연령에 대하여는 좌 우안에서 모두 높은 통계적 연관성을 보였다(p<0.01). 따라서 이 상의 결과로 근로자가 유기용제 중독으로 인해 초기 신경계이상의 증상으로 후천적 색각이상이 존재할 수 있으므로 안보건 사업에서의 또 하나의 일환으로 근로자의 안보건상태에 대한 지속적인 관심과 관리가 필요하다.

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다제내성결핵 환자에서 표준 1차 항결핵제 치료 중 발생한 획득 내성 (Acquired Drug Resistance during Standardized Treatment with First-line Drugs in Patients with Multidrug-Resistant Tuberculosis)

  • 전두수;김도형;강형석;민진홍;성낙문;황수희;박승규
    • Tuberculosis and Respiratory Diseases
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    • 제66권3호
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    • pp.198-204
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    • 2009
  • 연구배경: 다제내성결핵 치료에서 감수성으로 증명된 1차 항결핵제는 가장 항결핵효과가 큰 약제로 알려져 있다. 본 연구는 다제내성결핵 환자에서 표준 1차 항결핵제사용 후 1차 항결핵제에 대한 추가 내성 획득의 빈도와 그 위험 인자를 알아보고자 시행되었다. 방 법: 2004년 1월에서 2008년 5월까지 국립마산결핵병원에서 약제감수성 검사가 보고되기 전 표준 1차 항결핵제로 치료받은 다제내성결핵 환자 중에서 1차 항결핵제 치료 전과 1차 항결핵제 치료 후의 연속된 두 시점의 약제 감수성 검사 결과가 모두 있는 환자를 대상으로 하여 의무기록을 후향적으로 검토하였다. 결 과: 표준 1차 항결핵제로 치료 받은 41명 중 14명 (34.1%)에서 ethambutol (EMB) 혹은 pyrazinamide (PZA)에 대한 추가 내성이 획득되었다. 치료 전 isoniazid (INH), rifampicin (RFP)에만 내성을 보였던 11명 중 3명(27.3%)에선 EMB와 PZA에 동시 내성, 3명(27.3%)에선 PZA에 추가 내성이 획득되었다. INH, RFP, EMB에 내성을 보인 18명 중 6명(33.3%)에서 PZA에, INH, RFP, PZA에 내성을 보인 6명 중 2명(33.3%)에서 EMB에 추가 내성이 획득되었다. 대상 환자 중 10명(24.4%)에서 1차 항결핵제 치료 전 내성이었던 약제가 치료 후 감수성으로 전환되었다. 추가 내성획득과 연관된 통계학적으로 유의한 위험인자를 발견할 수 없었다. 결 론: 우리나라의 다제내성결핵 치료에서 1차 항결핵제는 추가 획득 내성의 위험을 고려하여 주의 깊게 사용해야 할 것으로 사료된다.

산정방법에 따른 단말뚝의 지지력 비교연구 (A Comparative Study on Bearing Capacity of Single Pile Based on Calculation Method)

  • 이영대;심재현
    • 한국농공학회지
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    • 제39권2호
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    • pp.124-133
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    • 1997
  • Pile load test is good for estimating pile bearing capacity, but using this method is limited by time and cost required. Dynamic and static method is more convenient and economical, but confidence of estimated value by dynamic and static method are lower than that of pile load test. After being compared pile bearing capacity data obtained from pile load test with those of other two methods, the results from this study were summarised as follows. For allowable bearing capacity values greater than 175t per pile, bearing capacity acquired from static method was higher than that acquired from pile load test, whereas bearing capacity acquired from pile load test was higher than that acquired from static method for values under 175 per pile. It was that variance of bearing capacity was large when bearing capacity obtained by dynamic method was higher than 250t. Also bearing capacity based on dynamic method was higher than that based on pile load test. Allowable bearing capacity get from dynamic method suggested that carefull precautions are necessary in application for allowable bearing capacity values higher than 2S0ton per pile.

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개심술 211례에 대한 임상적 고찰 (Clinical experience of open heart surgery: 211 cases)

  • 강인득
    • Journal of Chest Surgery
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    • 제17권4호
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    • pp.804-810
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    • 1984
  • Two hundred twenty one cases of open heart surgery were done in the Department of Thoracic and Cardiovascular Surgery, Pusan National University Hospital from July, 1981 to October, 1984. 1.There were 154 cases [73%] of congenital anomalies and 57 cases [27%] of acquired valvular heart diseases. Among the congenital cases, 128 cases were acyanotic and 26 cases were cyanotic. Among the 57 cases of acquired valvular replacement surgery, 3 cases had open heart commissurotomy, one had Kay annuloplasty. 2.The age distribution of the congenital acyanotic anomalies ranged from 5 to 32 years with mean age of 12.8 years, the congenital cyanotic anomalies from 3 to 29 years with mean age of 14.2 years and the acquired valvular diseases from 9 to 51 years with mean age of 30 years. The difference of sex distribution was no significance. 3.Three methods for debubbling process were used in our institute, in 133 cases, the vent was inserted into the left ventricular apex, in 61 cases inserted into the left atrium through right superior pulmonary vein and in 17 cases used needle aspiration only. 4.For cardioplegia, the GIK solution was infused repeatedly from 30 to 40 minutes interval and brought excellent results for myocardial protection during open heart surgery. 5.Overall mortality was 7.6%. The mortality along with each disease is 1.56% in congenital acyanotic cases, 26.9% in congenital cyanotic cases and 12.3% in acquired valvular disease.

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Isolation Rate of Methicillin-Resistant Staphylococcus aureus (MRSA) from Nasal cavity inferior regions and Cellular phones

  • Kim, Chung Hwan;Lee, Jun Young;Kim, Mi Kyeong;Kim, Sung Hwan;Park, Geun Young;Bae, So Yeon;Seo, Myeong Jin;Go, In Hyeog
    • 대한임상검사과학회지
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    • 제44권3호
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    • pp.118-123
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    • 2012
  • Nosocomial infection and community-acquired infection with Staphylococcus aureus, especially methicillin-resistant S. aureus (MRSA), has become a strong concern in human body sites and related effects. The aim of this study is investigate the isolation rate of MRSA from nasal cavity inferior regions and cellular phones to assess the risk factor of nosocomial infection and community-acquired infection. 34.7% and 37.2% isolates were MRSA from the nasal cavity inferior regions and cellular phones according to a Mannitol salt agar (added oxacillin $6{\mu}g/mL$) culture and PCR according to S. aureus specific 16S rRNA and mecA primers. Thus, the distribution of S. aureus and the isolation rate of MRSA represent a very high risk factor regards nosocomial infection and community-acquired infection.

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Application assessments of concrete piezoelectric smart module in civil engineering

  • Zhang, Nan;Su, Huaizhi
    • Smart Structures and Systems
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    • 제19권5호
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    • pp.499-512
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    • 2017
  • Traditional structural dynamic analysis and Structural Health Monitoring (SHM) of large scale concrete civil structures rely on manufactured embedding transducers to obtain structural dynamic properties. However, the embedding of manufactured transducers is very expensive and low efficiency for signal acquisition. In dynamic structural analysis and SHM areas, piezoelectric transducers are more and more popular due to the advantages like quick response, low cost and adaptability to different sizes. In this paper, the applicable feasibility assessment of the designed "artificial" piezoelectric transducers called Concrete Piezoelectric Smart Module (CPSM) in dynamic structural analysis is performed via three major experiments. Experimental Modal Analysis (EMA) based on Ibrahim Time Domain (ITD) Method is applied to experimentally extract modal parameters. Numerical modal analysis by finite element method (FEM) modeling is also performed for comparison. First ten order modal parameters are identified by EMA using CPSMs, PCBs and FEM modeling. Comparisons are made between CPSMs and PCBs, between FEM and CPSMs extracted modal parameters. Results show that Power Spectral Density by CPSMs and PCBs are similar, CPSMs acquired signal amplitudes can be used to predict concrete compressive strength. Modal parameter (natural frequencies) identified from CPSMs acquired signal and PCBs acquired signal are different in a very small range (~3%), and extracted natural frequencies from CPSMs acquired signal and FEM results are in an allowable small range (~5%) as well. Therefore, CPSMs are applicable for signal acquisition of dynamic responses and can be used in dynamic modal analysis, structural health monitoring and related areas.

Acquired Portosystemic Shunts Secondary to Hepatic Microvascular Dysplasia in a Young Dog

  • Hwang, Taesung;An, Soyon;Kim, Ahreum;Han, Changhee;Huh, Chan;Lee, Hee Chun
    • 한국임상수의학회지
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    • 제37권2호
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    • pp.88-90
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    • 2020
  • A one year old spayed female Bichon Frise dog presented with gait abnormalities and seizure. Serum biochemical results showed elevated levels of alkaline phosphatase, alanine aminotransferase, and ammonia. Serum bile acid level was also increased to be over 30 μmol/L on preprandial. Urinalysis identified the presence of ammonium urate crystal. Abdominal ultrasonography and CT revealed aberrant, tortuous, and multiple small vessels connected to the caudal vena cava between left kidney and caudal vena cava. Macroscopic specific findings associated with extrahepatic congenital portosystemic shunts (PSS) or other liver diseases were not identified. Liver biopsy was performed. Histopathologic evaluation revealed hepatic lobular hypoplasia with portal arterial duplication and vascular shunts. Based on these finding, this case was diagnosed as multiple acquired PSS secondary to hepatic microvascular dysplasia (HMD) and hepatic encephalopathy. A liver biopsy is recommended to differentiate HMD from other liver diseases and to confirm HMD when a young dog has multiple acquired PSS.